EXP 9 Flashcards
CONTAINERS A.K.A.
PHARMACEUTICAL PACKAGING
PACKAGING IS DEFINED AS THE
COLLECTION OF DIFFERENT
COMPONENTS WHICH SURROUNDS THE
PHARMACEUTICAL PRODUCT FROM THE
TIME OF PRODUCTION UNTIL ITS USE
PRIMARY PACKAGING- a.k.a
immediate/sales packaging
direct contact with the drug product; should be inert
PRIMARY PACKAGING
PRIMARY PACKAGING EXAMPLES
blister packs, strips, bottles
covering that follows the primary packaging
SECONDARY PACKAGING
used to provide bulk handling or shipping of pharmaceutical from one place to another
TERTIARY PACKAGING
COMPOSITION OF PACKAGE
CONTAINER
CLOSURE
CARTON
CARGO BOX
storage device in which the product is enclosed in
CONTAINER
- part of a container, tightly packed the container to prevent oxygen, co2, and moisture to be released or absorb by and to the drug product
CLOSURE
- secondary protection (secondary packaging); from environmental haZards
CARTON
made of cardboard or wood, prime
protection against external hazards
CARGO BOX
ACCORDING TO THE USP, A
CONTAINER
IS
“THAT WHICH
HOLDS THE ARTICLE AND IS OR MAY
BE IN DIRECT CONTACT WITH THE
ARTICLE.”
THE IDEAL CONTAINER OR
PACKAGE SHOULD:
- PROTECT THE CONTENTS FROM THE FOLLOWING ENVIRONMENTAL
HAZARDS - PROTECTS THE CONTENT FROM
THE FOLLOWING MECHANICAL
HAZARDS - THEY MUST NOT ADD OR
PERMIT LOSS TO ITS CONTENTS: - MUST HAVE A PHARMACEUTICALLY
ELEGANT APPEARANCE. - MUST BE CONVENIENT AND EASY
TO USE BY THE PATIENT. - MUST BE CHEAP AND ECONOMICAL
- MUST NOT REACT WITH THE CONTENT (INERT)
- MUST BE BIODEGRADABLE (IDEAL)
ENVIRONMENTAL
HAZARDS:
LIGHT
TEMPERATURE
MOISTURE
ATMOSPHERIC GASES
PARTICLES
MICROORGANISMS
MECHANICAL HAZARDS
VIBRATION
COMPRESSION
SHOCK
PUNCTURE
ABRASION
PROTECT THE CONTENTS FROM BOTH
LOSS AND
GAIN OF WATER.
PROTECT THE CONTENTS FROM
LOSS OF VOLATILE
MATERIALS
MUST _____ INTO THE CONTENTS.
MUST NOT LEACH ANYTHING TO THE CONTENTS.
NOT SHED PARTICLES; NOT LEACH
FOUR TYPES OF CONTAINER
WELL CLOSED CONTAINER
TIGHT CONTAINER
HERMETIC CONTAINER
LIGHT-RESISTANT CONTAINER
- PROTECTS AGAINST EXTRANEOUS SOLIDS AND LIQUIDS E.G. AMPULES AND VIALS
WELL CLOSED CONTAINER
PROTECTS FROM EXTRANEOUS SOLIDS, LIQUIDS
OR VAPORS
TIGHT CONTAINER
FROM LOSS OF DRUG AND FROM EFFLORESCENCE, DELIQUESCENCE, OR EVAPORATION
TIGHT CONTAINER
- GENERALLY STERILE
- IMPERVIOUS TO AIR OR ANY OTHER GASES UNDER ORDINARY CONDITIONS OF HANDLING, SHIPMENT, STORAGE AND DISTRIBUTION
HERMETIC CONTAINER
PROTECTS THE CONTENTS FROM PHOTOCHEMICAL
DETERIORATION
LIGHT-RESISTANT CONTAINER
LIGHT-RESISTANT CONTAINER e,g,
LIGHT-RESISTANT CONTAINER
EXAMPLES OF DRUG
CONTAINERS:
- BLISTER PACK
- SIFTER-TOP CONTAINER
- PRESCRIPTION BOTTLE
- AMBER FLUTED BOTTLE
- COLLAPSIBLE TUBE
- OINTMENT JAR
- NASAL SPRAY
- METERED DOSE INHALER
- ROUND VIALS
- WIDE-MOUTH BOTTLE
- DROPPER BOTTLE
- APPLICATOR BOTTLE
- SLIDE BOXES
- AMPOULE
- VIAL
- AUTO-INJECTOR
- PENS
- DROP COUNTER
COMMONLY USED AS UNIT DOSE; TABLETS CAPSULES, LOZENGES
BLISTER PACK
A DISPOSABLE PACKAGE
CONSISTING OF A CLEAR PLASTIC
OVERLAY AFFIXED TO A
CARDBOARD BACKING FOR
PROTECTING AND DISPLAYING A
PRODUCT
BLISTER PACK
IDEAL CONTAINER FOR POWDERS TO BE APPLIED BY SPRINKLING
SIFTER-TOP CONTAINER
SIFTER-TOP CONTAINER EXAMPLE
E.G. DUSTING POWDERS, GRANULAR PRODUCTS
USED FOR
HOLDING PILLS
OR MEDICINES
PRESCRIPTION BOTTLE
PRESCRIPTION BOTTLE SHAPE
CYLINDRICAL
PRESCRIPTION BOTTLE A.K.A
MEDICINAL BOTTLES; CHEMICAL/ DRUGGIST BOTTLES
IDEAL FOR LIGHT
SENSITIVE
MEDICINES.
AMBER FLUTED BOTTLE
AMBER FLUTED BOTTLE HAVE A PRESENCE OF?
FLUTE
FLUTE A.K.A.
RIB
