Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Locomotor & Exercise > Exercise Phys: Oxygen, Heat, & Fluids > Flashcards

Exercise Phys: Oxygen, Heat, & Fluids Flashcards

1
Q

T/F At a given PO, oxygen uptake differs between trained and untrained individuals on a cycle ergometer

A

False; mechanical efficiency for cycling is about the same tf oxygen uptake is the same

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the maximal oxygen uptake?

A

Point at which an increase in PO does not result in ay further increase in oxygen uptake

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Oxygen uptake is dependent on

A

exercise intensity; slow increase to steady state, then no further increase beyond maximal O2 uptake

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the cardiovascular response to exercise?

A

increase O2 supply to skeletal and cardiac muscle; facilitate CO2 and heat removal (generated in aerobic metabolism); maintain MAP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Fick equation

A

VO2 = Q x (CaO2 - CvO2) = whole body O2 uptake is equal to whole body CO times difference between arterial and venous concentrations of O2 (AvO2 difference)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Only ___% of O2 consumption is used in mechanical work; extra energy is ____________

A

20%; dissipated as heat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which tissues increase metabolic rate during exercise?

A

Skeletal and cardiac muscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Increase in CO is about _____ per L of O2 uptake increase

A

5-6L

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What happens to muscle blood flow in exercise?

A

Increases; 90% of CO at max exercise

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What happens to coronary circulation during exercise??

A

Increases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the purpose of vasoconstriction of vascular beds during exercise?

A

increase in muscle bloodflow occurs via peripheral vasodilation; CO increases to maintain MAP but because MAP = CO x TPR, TPR must also be increased to maintain MAP - this is achieved by vasoconstricting other vascular beds to oppose peripheral vasodilation to muscles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What happens to splanchnic blood flow during exercise?

A

decreases; vascular bed can be severely constricted and endanger the GIT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What happens to renal blood flow during exercise?

A

decreases; kidney is vasoconstricted tf reduced urine concentration; GFR is also reduced to decrease urine production and conserve water

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What happens to skin blood flow during exercise?

A

increased early on (vasodilation) to dissipate heat; reduced approaching max CO/intensity (vasodilation) to maintain TPR - can no longer dissipate heat!!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

T/F Muscle blood flow is a target of vasoconstriction in exercise

A

True; approaching max, muscles can become a target for vasoconstriction - muscle wins out over skin but brain wins out over muscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Why do we get an increase in muscle blood flow during exercise?

A

Metabolic vasodilators from contracting skeletal muscle, endothelium (NO), and/or RBCs; muscle pump; conducted vasodilation; functional sympatholysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What role does the endothelium play in vasodilation?

A

Initial increase in flow causes shear stress on the endothelium that stimulates NO release

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What role do RBCs play in vasodilation?

A

as Hb becomes desaturated, red cells release ATP which binds to purinergic receptors on vascular smooth muscle causing vasodilation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is conducted vasodilation?

A

local depolarisation releases ACh which depolarizes local vascular smooth muscle causing proximal spread via gap junctions leading to upstream dilation in resistance arterioles in larger vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What is functional sympatholysis?

A

Giving a vasoconstrictor stimulus to a muscle is much less effective if the muscle is contracting and much more effective if it is at rest - some dilators desensitize sympathetic nerve endings and receptors such that the sympathetic vasoconstrictor effect is blunted

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What is the difference in CO between trained and untrained individuals during exercise?

A

CO increases similarly but trained individuals reach a much higher CO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What is the difference in A-VO2 difference between trained and untrained individuals during exercise?

A

Similar; even at max trained is only slightly higher

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What is thought to be the reason for increased VO2 max in trained individuals vs untrained?

A

Increase in CO - trained can reach a higher CO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

How is a higher CO attained in trained individuals?

A

lower HR and higher SV due to larger chamber size and expanded blood volume

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Systolic blood pressure reflects

A

CO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Diastolic blood pressure reflects

A

TPR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

What happens to DBP as you approach maximum intensity?

A

relatively stable, may fall slightly due to vasodilation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

What happens to SBP as you approach maximum exercise intensity?

A

increases bc CO is increasing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

What happens to MAP as you approach maximum exercise intensity?

A

increases slightly bc increase in SBP is greater than decrease in DBP and bc length of time in diastole is decreasing (due to increased HR)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Does MAP track more with SBP or DBP?

A

SBP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

What is unique about MAP and HR in exercise?

A

only situation where MAP and HR both increase; normally baroreflex will decrease the HR but this is reset during exercise to a higher operating level

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

What happens to HR in prolonged exercise?

A

Increases

33
Q

What happens to TPR in prolonged exercise?

A

increases to offset the big decrease in SV, meaning CO falls slightly

34
Q

What happens to blood volume in prolonged exercise?

A

decreases due to sweating and volume loss but is reasonably protected; interstitial and intracellular volumes are challenged to a greater extent

35
Q

What happens to MAP in prolonged exercise?

A

might fall slightly; if this drops when you stop exercising you get postural hypotension

36
Q

What is meant by cardiovascular drift?

A

MAP and SV decrease while HR increases; HR increases due to reduction in SV and displacement of blood to the periphery - decrease in SV may also be due to shorter diastole w/increased HR tf shorter filling tf less blood is ejected

37
Q

Cardiovascular drift (inc HR, decreased SV) is related to

A

hyperthermia, dehydration, increased plasma adrenaline, and somewhat to peripheral displacement of blood volume due to cutaneous vasodilation

38
Q

What is the risk of exercising in water in cardiac failure?

A

Hydrostatic pressure opposes peripheral displacement of blood volume to the skin - this causes an increase in central blood volume and tf can volume overload the patient

39
Q

How is circulation controlled neurally?

A

central command - HR and MAP increase in anticipation of exercise; feedback from peripheral sensors about muscle etc.; feed-forward command resets baroreceptor to a higher level to allow some increase in BP

40
Q

How does the ANS affect HR in exercise?

A

Initial increase in HR is due to vagal (PSNS) withdrawal; then an increase in SNS activity

41
Q

What are the mechanisms of increased CO following training?

A

expanded blood volume (= diluted haematocrit, hence EPO doping); Frank-Starling mechanism; increased heart size; increased LV mass and chamber size; increased adrenergic sensitivity (SA node may change intrinsic properties = lower HR)

42
Q

What is considered to be the hallmark of training?

A

Decreased HR

43
Q

What microvascular adaptations occur in response to exercise training?

A

increased capillary density and increased capillary recruitment

44
Q

How is oxygen delivery enhanced in trained muscle?

A

increased capillary density and recruitment - even though AvO2 doesn’t change much from UT to T, the total mass of O2 delivered is enhanced bc of this

45
Q

What are the respiratory responses to exercise?

A

maintain arterial O2 saturation; CO2 removal; acid-base balance compensating for metabolic acidosis; fluid and temperature balance (heat and fluid are lost in hyperventilation)

46
Q

What happens to ventilation with increasing exercise intensity?

A

early exercise: VE tracks with increasing O2; ventilatory threshold 1 (VT1): VE increases slightly, starting to get metabolic acids; at higher intensities (VT2) further stimuli increase VE =relative hyperventilation

47
Q

How do arterial paO2 and paCO2 change during incremental exercise?

A

Until VT2, arterial paO2 and paCO2 are constant at resting levels; once you start hyperventilating paO2 increases a little while paCO2 drops significantly due to hyperventilation = relative hyperventilation

48
Q

At rest, mixed venous PvO2 is

A

~40mmHg

49
Q

At rest, arterial PaO2 is

A

~100mmHg

50
Q

Alveolar PAO2 is

A

~150mmHg

51
Q

PiO2 is

A

~100mmHg

52
Q

What happens to PvO2 with exercise?

A

drops because more O2 is extracted

53
Q

How is ventilation controlled?

A

chemical inputs from central and peripheral chemoreceptors; stretch receptors in the lung; mechanoreceptors in muscle

54
Q

What drives ventilation during exercise?

A

motor cortical activation (same as +HR); muscle afferents from spindles and type III & IV fibres; CO2 flux to the lung (mixed venous chemoreceptor?); increased K+, H+, lactate, catecholamines, and temperature; NOT O2

55
Q

What happens to exercise ventilation with training?

A

ventilation is lower for a given PO; reduced lactate/H+, K+, plasma catecholamines, activation of muscle afferents, and central drive; can achieve same arterial saturation for relatively less VE input

56
Q

What factors determine VO2 max potential?

A

training, genetics

57
Q

Sedentary VO2max

A

30mL O2/kg body mass/minute

58
Q

Normally active-conditioned VO2max

A

40-50mL O2/kg/min

59
Q

Endurance VO2max

A

80mL O2/kg/min

60
Q

What factors determine VO2 max in exercise?

A

primarily by O2 delivery (respiration, ventilation, ventilation-perfusion matching, diffusion); central circulation (Hb, BP, max CO); peripheral circulation (local BF, capillary density); metabolism in muscle (mitochondria)

61
Q

VO2 max is primarily determined by

A

O2 delivery

62
Q

T/F O2 consumption in the muscle is the major determinant of VO2 max

A

False; O2 delivery is the major determinant of VO2 max

63
Q

What are the mechanisms of heat exchange during exercise?

A

conduction (major heat loss in water), convection, radiation, evaporation of sweat (major heat loss mechanism in air)

64
Q

T/F Sweating causes heat loss

A

False; the evaporation of sweat causes heat to be lost - there MUST be a phase change - tf in humidity sweating is not an effective mechanism, lose fluid but not heat

65
Q

What happens to heat loss in humid environments?

A

Fluid is lost to sweating but not heat because it cannot be evaporated

66
Q

At lower temperatures, heat is primarily lost by

A

convection and conduction, some radiation

67
Q

As temperature increases, heat is predominantly lost by

A

evaporation of sweat; less of a contribution from convection & conduction, and radiation

68
Q

T/F Respiration contributes significantly to heat loss

A

False, relatively less significant than evaporation, convection, conduction, radiation

69
Q

Heat is transferred from muscle via

A

overlying skin and via cardiovascular system (vasodilation)

70
Q

What is the risk of heat to elderly people with cardiac problems?

A

In the heat, skin vascular beds vasodilate - tf a lot of CO is going to the skin, so CO is increased, but as activity increases the muscle demands more blood flow and you get vasoconstrction at the skin, making it harder to lose heat

71
Q

How does the brain auto-regulate body temperature and power output?

A

The brain reduces power output in hotter temperatures to maintain body temperature

72
Q

What is the benefit of pre-cooling?

A

Can lower the core body temperature so it takes longer to get to a temperature that is too hot to sustain exercise - maintain bloodflow to muscles for longer, longer duration before flow has to be diverted to the skin to lose heat

73
Q

T/F Blood volume decreases in dehydration

A

False; blood volume is reasonably well protected but interstitial and intracellular dehydration occurs

74
Q

What are the benefits of fluid ingestion relative to no fluids?

A

increased blood volume; decreased HR; increased SV and CO; lower core temperature; lower plasma sodium and osmolality; reduced muscle glycogen use; enhanced exercise performance

75
Q

How is blood volume maintained or restored following exercise?

A

during exercise renal BF and GFR are reduced to retain fluid; in recovery, RAAS is activated which increases plasma aldosterone (salt retention), renin (Na and fluid), and ADH (fluid retention)

76
Q

What is critical to restoring water balance?

A

Restoring Na balance

77
Q

Sodium is the main cation of ECF or ICF?

A

ECF

78
Q

What is the importance of diuretics in exercise?

A

Need to closely monitor fluid replacement if exercising while taking diuretics because fluid is being lost through sweat

Locomotor & Exercise (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions