Excretion Flashcards

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1
Q

what is excretion

A

process of removing metabolic waste products, toxic substances and excess substances from the body

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2
Q

why is excretion necessary

A

so that harmful substances will not build up in the body to cause harm

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3
Q

what are the 2 functions of kidney

A

1) excrete metabolic waste products such as urea, excess water and mineral salts

2) regulates water potential and solute concentration in the blood to maintain a constant water potential in the body

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4
Q

what are ureters

A

narrow tubes connecting the kidneys to the urinary bladder

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5
Q

what is the urinary bladder

A

elastic muscular bag that stores urine

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6
Q

what is the urethra

A

duct which urine passes from the bladder to the outside of the body

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7
Q

what are the 4 parts that make up a kidney nephron

A

1) Bowman’s capsule
2) proximal convoluted tubule
3) loop on Henlé
4) distal convoluted tubule

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8
Q

describe the process of ultrafiltration

A
  • afferent arteriole being wider than the efferent arteriole creates a high blood pressure in the glomerulus to ensure a pressure difference
  • blood plasma is forced of the glomerular blood capillaries into the Bowman’s capsule
  • filtered blood plasma (glomerular filtrate) contains small, soluble substances forced out into the Bowman’s capsule
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9
Q

what are 3 adaptations of the glomerulus blood capillaries?

A

1) network of blood capillaries
- provides large surface area for ultrafiltration

2) one-cell thick walls with tiny pores
- shorter diffusion distance, allows small soluble substances to be filtered into the Bowman’s capsule

3) covered by a thin, partially permeable membrane (basement membrane)
- only allows very small, soluble molecules/ions to pass through
- impermeable to blood cells, platelets and large molecules (e.g. proteins)

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10
Q

what happens at the proximal convoluted tubule during selective reabsorption

A
  • most water reabsorbed by osmosis
  • most mineral salts reabsorbed by diffusion and active transport
  • all glucose and amino acids reabsorbed by active transport
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11
Q

what happens at the loop of Henlé during selective reabsorption

A
  • some water reabsorbed by osmosis
  • some mineral salts reabsorbed by active transport
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12
Q

what happens at the distal convoluted tubule during selective reabsorption

A
  • some water reabsorbed by osmosis
  • some mineral salts reabsorbed by active transport
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13
Q

what happens at the collecting duct during selective reabsorption

A
  • some water reabsorbed by osmosis
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14
Q

what is osmoregulation

A

maintenance of constant body water potential by controlling the water potential and solute concentration in the blood

*controlled by antidiuretic hormone (ADH)
*secreted/produced by hypothalamus, released into bloodstream by pituitary gland

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15
Q

what could happen if water potential in the blood is too high

A

water could enter the RBCs via osmosis and the RBCs would swell and may lyse

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16
Q

what could happen if water potential in the blood is too low

A

water could leave the RBCs via osmosis and the RBCs would shrink and crenate

17
Q

what happens if the water potential in the blood is too high

A
  • pituitary gland releases less antidiuretic hormone (ADH)
  • cells in the walls of the collecting ducts become less permeable to water; less water reabsorbed from collecting ducts into blood capillaries
  • larger volume, lower concentration of urine produced
  • water potential of blood returns to normal
18
Q

what happens if the water potential in the blood is too low

A
  • pituitary gland releases more antidiuretic hormone (ADH)
  • cells in the walls of the collecting ducts become more permeable to water; more water reabsorbed from collecting ducts into blood capillaries
  • smaller volume, higher concentration of urine produced
  • water potential of blood returns to normal
19
Q

what are 3 causes for kidney failure

A

1) high blood pressure
2) diabetes
3) alcohol abuse

20
Q

what is the process of kidney dialysis

A
  • blood drawn from vein in patient’s arm is pumped through tubing in dialysis machine
  • tubing bathed in a specially-controlled dialysis machine, walls of tubing partially permeable
  • small molecules diffuse out of the tubing into the dialysis fluid; blood cells, platelets and large molecules (e.g. proteins) remain in the blood
21
Q

what are 3 features of dialysis machines

A

1) dialysis tubing is narrow, long and coiled
- increases surface-area-to-volume ratio to speed up rate of exchange of substances between blood and dialysis fluid

2) blood flows in the opposite direction of dialysis fluid
- maintains concentration gradient for complete removal of urea from blood into dialysis fluid

3) dialysis fluid (37°C) has the same composition as blood but lacks nitrogenous waste
- prevents essential molecules (e.g. glucose and amino acids) from diffusing out of the blood into the dialysis fluid due to the lack of a concentration gradient
- absence of nitrogenous waste maximises concentration gradient for fast removal of such waste from blood via diffusion
- set at 37°C to prevent loss/gain of body heat