Excitable cell Flashcards

1
Q

Forces that control ion movement

A

diffusion and electrical field

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2
Q

How much current depends on

A
electrical potential (V)
Electrical conductance - how easy it is for charge to more from on point to another 

there is no flow if either of these = 0

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3
Q

conductance measured in ?

A

siemens

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4
Q

nernst equation vs goldmans

A
N = just 1 ion taken into account. calculates equilibrium potential
G = looks at relative permeabilities of more than 1 ion
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5
Q

Action of calcium

A

pumps transpot calcium out of neuroness maintaining low intracellular. changes detected by many proteins used as a signalling ion
high intracellular concentration is toxic

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6
Q

Eion?

A

equilibrium potential

if membrane where selectively permeable to that ion calculated using nernst equation

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7
Q

Graded vs action potential

A

graded - variable size, pass both ways along neurone membrane. vary according to strength to stimulus
action - all or nothing, fixed size, propagate in 1 direction

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8
Q

resting potential ?

A

set up by pumps that maintain distribution of charge molecules. sodium potassium atpase transport 2k into cell and 3na out

set up negative membrane potential

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9
Q

Sodium channels

A

open in response to a depolarisation
need to repolarise so can remove the innactivation ball so can go again= refractory period
K channels lead to repolarisation
Na channels behind are closed s lead to unidirectional

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10
Q

Factors affecting velocity ?

A

diameter - greater diameter the greater V

Myelin - insulate to stop leaking by saltatory conduction

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11
Q

EPSP +IPSP

A

excitatory post synaptic potential and inhibitor.

eps can be shunted by the activation of a nipsp

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12
Q

temporal vs spatial summation

A

spatial - multiple presynaptic

temporal - 1 over time

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