Excipients

Question 1

Glidant/Lubricant for powders

Answer 1

magnesium sterate

Question 2

Surfactant for powders

Answer 2

sodium lauryl sulfate

Question 3

Magnesium Oxide

Answer 3

adsorbent powder

Question 4

Magnesium carbonate

Answer 4

adsorbent powder

Question 5

Kaolin

Answer 5

adsorbent powder

Question 6

Eutectic mixtures

Answer 6

when two components are mixed they melt at a lower temperature than the melting temperature of the individual component

Question 7

Glycerol

Answer 7

plasticizers

Question 8

Sorbitol

Answer 8

plasticizers

Question 9

hard lozenges

Answer 9

sucrose or syrup

Question 10

soft lozenges

Answer 10

PEG

Question 11

chewable lozenges

Answer 11

glycerin or gelatin

Question 12

Emulsion

Answer 12

liquid dispersed in a liquid.
heterogeneous.
need emulsifier to bring two phases closer together

Question 13

Suspension

Answer 13

solid dispersed in a liquid.
heterogeneous.
wetting agent/levigating agent is a surfactant used to incorporate insoluble drug into a liquid to make suspension.

Question 14

Levigating agents

Answer 14

Glycerin
Mineral oil
Polyethylene glycol
Propylene glycol

Question 15

Surfactants

Answer 15

help two compounds that resist each other to move closer together by reducing the surface tension

Question 16

Emulsifier

Answer 16

Surfactant that reduces surface tension between oil/water

Question 17

HLB number

Answer 17

Low HLB <10: oil soluble and used for water in oil emulsions

High HLB >10: water soluble and used for oil in water emulsions

Question 18

Adsorbents

Answer 18

Keep powders dry

Magnesium oxide, magnesium carbonate, kaolin

Question 19

Anti-adherent

Answer 19

Prevents tablet ingredients from sticking to punches

Magnesium stearate

Question 20

Anti-foaming agent

Answer 20

Simethicone

Question 21

Antioxidant

Answer 21

Ascorbic acid

Question 22

Coatings

Answer 22

Prevent degradation due to oxygen, light, moisture

Shellac, gelatin, gluten

Question 23

Diluents

Answer 23

Add size to small dosages

lactose, starches, calcium salts, mannitol, sorbitol, cellulose

Question 24

Disintegrant

Answer 24

Alginic acid, polacrilin potassium (amberlite), cellulose products, starches, Nu-Tab

Question 25

Emollient

Answer 25

Provides a barrier and acts as a vehicle for drug delivery

Petroleum jelly, Aquaphor, Vaseline

Question 26

Enteric-coating

Answer 26

Cellulose acetate phthalate shellac

Question 27

Flavoring agent

Answer 27

Artificial, sugar free: aspartame and saccharin

glycerin, dextrose, lactose, mannitol, sorbitol, phenylalanine

Question 28

Gelling (Thickening) agent

Answer 28

agar, alginates, guar gums, acacia, GELATINS, tragacanth BENTONITE, carbomer, cellulose, starches

Question 29

Gildant in tablet/caps

Answer 29

Colloidal silica

Question 30

Hydrophilic solvent

Answer 30

dissolves solvents in liquids with high miscibility with water

PEG, alcohols

Question 31

Hydrophobic solvent

Answer 31

dissolves solvents in liquids with low miscibility with water

Oils, Fats

Question 32

Levigating agent

Answer 32

Mineral oil, glycerin

Question 33

Lubricants

Answer 33

keep ingredients from sticking together

calcium and magnesium stearate

Question 34

Preservatives

Answer 34

prevent growth of bacteria and other pathogens

chlorhexidine, EDTA, sodium benzoate, benzoic acid, benzalkonium chloride, thimerosal

Question 35

Oil soluble suppository base

Answer 35

cocoa butter, vegetable oil, glycerin

Question 36

water soluble suppository base

Answer 36

PEG, mineral oil

Question 37

Continental Gum Method (Dry Gum Method)

Answer 37

Levigate gum with oil, add water all at once, shake until cracking sound heard, add other ingredients, add water to final volume

Question 38

English Gum Method (Wet Gum Method)

Answer 38

Triturate the gum and water, add oil slowly, add other ingredients, add water to final volume