Examination of Smell, Taste, and Hearing Flashcards
Where is the olfactory epithelium located at the mucous membrane lining of the nasal cavity?
Inferior portion of the cribriform plate at the ethmoidal plate
What cells are responsible for olfaction?
Bipolar sensory cells
What is the main relay station for olfaction?
Olfactory bulb
What are the 3 olfactory striae (axons of olfactory bulb)? Which of these striae is the most important for smelling bcos this is where smells are pereceived?
Lateral olfactory striae - most important
Intermediate olfactory striae
Medial olfactory striae
What CN can be stimulated if u use alcohol or perfume for CN exam?
CN V1 - opthalmic division of the trigeminal nerve
What are the 4 conditions that can affect CN I?
- Fractures of cribriform plate of ethmoid bone
- Hemorrhage at base of frontal lobes
- Meningitis or abscess of frontal lobe
- Hypophyseal tumors
What condition is noted in px with olfactory groove or sphenoid ridge masses (meningiomas) or space occupying lesions of the frontal lobe?
Foster-Kennedy syndrome
What condition is noted in px w/ olfactory groove or sphenoid ridge masses (menangiomas) or space in the lesions of the frontal lobe?
Foster-Kennedy syndrome
What are the clinical presentation of Foster-Kennedy syndrome?
Ipsilateral anosmia
Ipsilateral optic atrophy
CL papilledema -> affected visual pathway
What CN I disorder is caused by a rare mutation that presents with congenital anosmia and hypogonadotropic hypogonadism?
Kallman syndorme
What gene is affected/mutated in Kallman syndrome?
KAL 1 gene
What are the imaging findings seen in Kallman syndrome?
Complete agenesis of the olfactory bulbs and sulci, OR medial orientation of the sulfatory sulci
What are the causes of Anosmia in COVID-19?
- Direct affectation of the virus through the Transmural pathway
- Hematogenous spread: breaking through the BBB
WHere are taste cells located?
Within the tongue epithelium
What is the innervation of the Anterior 2/3 of the tongue?
Chorda tympani (branch of CN VII)
What is the innervation of the posterior 1/3 of the tongue?
Afferents of the petrosal ganglion: CN IX
What innervates the epiglottis and larynx?
SUperior laryngeal nerve
Explain the GUstatory pathway?
Afferent tracts enter the brainstem —> synapses with ROSTRAL NUCLEUS OF THE SOLITARY TRACT —> gives afferent fibers to the IPSILATERAL pontine taste area as the CENTRAL TEGMENTAL TRACT —> IL Ventral-posteromedial nucleus of the thalamus —> IL primary gustatory area —> L hypothalamus & amygdala —> emotions with diff tastes
What are the objects used in examination of Gustation?
Sugar & salt soln
Disposable cotton applicator
Sterile gauze
H2O for drinking and gargling
What are the main indicators of localization for gustatory pathway?
Loss of appetite, smell, or taste
Bell’s palsy or idiopathic peripheral facial palsy
What CN is usually affected by UL loss of taste & at what side?
Ipsilateral CN VII
What is the medical torm for loss of taste due to affectation of taste buds?
Ageusia
Why is the sense of taste affected by COVID 19?
Virus binds to sialic acid receptors (taste bud) —> inflam & edema -> degradation & apoptiosis of taste receptors —> reduced salivary flow
What are the structures of the external/outer ear?
Pinna/Auricule
External auditory canal
Tympanic membrane
Where is the middle ear/tympanic cavity located?
within the temporal bone
What structure in the middle ear separates the middle and inner ear?
Oval and round windows
What are the parts of the bony ossicles?
Malleus
Stapes
Incus
What are the muscles found in the middle ear/tympanic cavity?
Tensor tympani
Stapedius
Where is the inner ear found?
Petrous portion of the temporal bone
What are the 2 systems of canal in the inner ear/
Osseus/bony labryinth
Membranous labyrinth
In the perilymph found in the Osseus/bony labyrinth, what cation is found in high concentraiton?
Na+
In the endolymph found in the Membranous labyrinth, what cation is found in high concentration?
K+
What are the 2 cavities of the membranous labyrinth?
Utricle - posterior with semicircular canal
Saccule - anterior with cochlea
What are the sensory areas of the membranous labyrinth and what part of the inner membrane are they located?
Maccule utriculi - L wall of the utricle
Maccule sacculi - floor of the saccule
What is the Organ of corti composed of?
Hair cells + Supporting cells
What are the main sensory/auditory receptors of the ear?
Hair cells
What are the main sensory/auditory receptors of the ear?
Hair cells
What stimulates hair cells near the oval window & hair cells near the apex of the cochlea?
Hair cells near apex of the cochlea -> LOWER frequencies/tone
Hair cells near oval window -> HIGHER frequencies/tone
What is the first order neuron in the auditory pathway?
neurons of spiral ganglion
What are the second order neuron in the auditory pathway?
Cochlear nuclei
in the cochlear nuclei, what structure receives fibers that innervate HIGH FREQUENCY basal hair cells?
Dorsal Cochlear nucleus
in the cochlear nuclei, what structure receives fibers that innervate LOW FREQUENCY basal hair cells?
Ventral cochlear nucleus
What are the structures found in the central nucleus of the inferior colliculus?
- Dorsal acoustic striae -> from DORSAL COCHLEAR NUCLEUS
- Intermediate acoustic striae -> from DORSAL PART OF VENTRAL COCHLEAR= NUCLEUS
- Ventral acoustic striae -> from the VENTRAL COCHLEAR NUCLEUS
Where does the ventrial acoustic striae terminate?
IL & CL reticular formation, superior olivary nuclei, and nuclei of the trapezoid body
Where are the third order neurons found?
Inferior colliculus
Where in the medial geniculate body of the thalamus can LOW.& HIGH freq fibers end up?
Apical & L areas = LOW FREQ fibers
Middle portion of the nuclear mass = HIGH FREQ fibers
Where are the fourth order neurons found?
Medial geniculate nucleus
What cortex does the fourth order neuron project to?
primary auditory cortex (BA 41, 42) in the superior temporal gyrus
In the primary auditory cortex, where do high & low frequencies terminate?
Medially = HIGH freq
Laterally = LOW freq
How do you diagnose if it is a Conductive hearing loss?
Weber test = Lateralizes to the ABNORMAL ear
Rinne test = Bone conduction > Air conduction
What part of the ear is affected in Conductive hearing loss?
conduction of sound waves in the middle ear
What causes Conductive hearing loss?
impacted cerumen
chronic otitis media
otosclerosis
How do you diagnose Sensorineural hearing loss?
Weber test = lateralizes to the NORMAL side
Rinne test = AC > BC
Where is the problem in sensorineural hearing loss?
inner ear = Organ of corti, CN VIII, cochlear neuclei of the pons, central auditory pathway
What are the causes of sensorineural hearing loss?
any central cause for the hearing loss