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1
Q

CN III compression

A

Ptosis
Mydriasis
Down ^ out
Paralysis of accommodation (cycloplegia)

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2
Q

MAO inhibitors

MAO Takes Pride In Shanghai

A

Tranylcypromine
Phenelzine
Isocarboxazid
Selegiline (selective MAO-B inhibitor)

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3
Q

Sclerosing cholangitis is assoc w/

A

Ulcerative colitis = bloody diarrhea ^ inflammatory “pseudopolyps”

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4
Q

Stroke volume = ?

A

LVEDV - LVESV

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5
Q

Aortic stenosis leads to

A

⬆️LVEDV
⬆️LVESV
⬆️peak systolic pressure

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6
Q

Doxorubicin

Which drug prevent cardiotoxicity ?

A

Anthracycline ATB

Dexrazoxane: derivative of EDTA

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7
Q

Cisplatin

A

Amifostine: ⬇️renal toxicity

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8
Q

Methotrexate

A

Leucovorin diminish toxicity

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9
Q

Cyclophosphamide ^ ifosfamide

A

Mesna reduce incidence of hemorrhagic cystitis

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10
Q

Cholera toxin interacts w/ ?

A

G protein

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11
Q

Ewing sarcoma

A

S-100

Homer-wright pseudorosettes

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12
Q

Nerve that courses around the medial malleolus

A

Posterior tibial nerve

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13
Q

Blood supply of the pancreas

A

Body ^ tail: splenic artery SPLENIC ARTERY

Head: inf pancreaticoduodenal artery SMA

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14
Q

Specialized transduction

A

All of the progeny phage would be identical and able to transduce

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15
Q

Drug that blunt postprandial increase in plasma glucose

A

Acarbose

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16
Q

Lesion that damages the common peroneal nerve

A

A lesion near the neck of the fibula

Superficial: eversion, dorsum
Deep: dorsiflexion

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17
Q

44yo rapid onset of hematuria, HTN ^ renal failure

A

RPGN: proliferation of cells in the urinary space of most of the glomeruli

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18
Q

Glucokinase

A

Hepatocytes and pancreas

Glucose phosphorylation, trapping ^ insulin release

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19
Q

Epidural hematoma

A

Regain consciousness and have a Lucid period that lasts several hours

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20
Q

Drugs w/ alfa blocking activity

A

Antipsychotics: chlorpromazine

TCA

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21
Q

Withdrawal sx that causes life threatening symptoms ?

A

Barbiturates

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22
Q

SIADH

A

⬇️plasma osmolarity

⬇️plasma sodium

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23
Q

Alexia w/o agraphia

Left PCA

A

Lef occip cortex

Splenium of the corpus callosum

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24
Q

Intestinal granulomatous diseases (2)

A 
Crohn disease (acid fast -)
Intestinal tuberculosis (acid fast +)
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25
Q

MCH I associated protein ?

A

B2-microglobulin

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26
Q

MCH II

associated protein ?

A

Invariant chain

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27
Q

Most important predictor of early and late stage HIV infection

A

Early: viral load
Late: CD4 count

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28
Q

Churg-Strauss syndrome

P-ANCA

A

Granulomas ^ vasculitis: lung, skin, peripheral nerves

Bronchial asthma, eosinophilia

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29
Q

bcl-2 overexpression

A

B cell lymphomas : follicular ^ undifferentiated

18 chrom

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30
Q

Aminoacids negatively charged at body pH? (2)

A

Aspartate

Glutamate

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31
Q

Which cell type develop sensitization to lepromin test ?

A

TH1 cell

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32
Q

Lead poisoning

Antidote ?

A

Succimer

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33
Q

Unilateral deafness

A

Cochlear nucleus deafness

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34
Q

Weber test

Vibrating tuning 🍽 in the middle of the head

A

Conductive: louder in the affected ear
Sensorineural: louder in the unaffected ear

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35
Q

Weber test

Vibrating tuning 🍽 in the middle of the head

A

Conductive: louder in the affected ear
Sensorineural: louder in the unaffected ear

36
Q

Schüffner’s dots
P vivax ^ ovale
Drug against hypnozoites ?

A

Primaquine

37
Q

Paget disease result from underlying?

38
Q

Drug to treat pregnant women w/gonorrhea who cannot tolerate a cephalosporin atb ^ children < 45 kg w/ uncomplicated gonococcal infections

A

Spectinomycin

39
Q

Oxybutynin

A

Muscarinic antagonist. Used to treat incontinence

40
Q

Glycogen molecules w/short outer branches

A

Cori disease

Debranching enzyme

41
Q

Long Chain acyl CoA dehydrogenase LCAD

A

Muscle weakness and cardiomiopathy

Fasting hypoglycemia ^ hypoketosis

42
Q

Hypoventilation

A

Does not produce A-a Po2 difference

⬆️A-a Pco2

43
Q

HUS

A

Occurs in children after infections w/E. Coli
Mild hemolytic anemia
Glomerular thrombosis ^ collapse

44
Q

Marantic endocarditis

A

Sterile vegetations
Fibrin precipitations
Along the line of closure of the mitral valve

45
Q

Chest trauma (2)

A

Cardiac contusion

Cardiac tamponade

46
Q

CCK functions ? (2)

A

Gallbladder contraction

Sphincter of Oddi relaxation

47
Q

Adrenocorical insufficiency

A

Weakness
Weight loss
Skin pigmentation

48
Q

Broad based budding yeast found in rotten wood

A

Blastomyces dermatitidis

49
Q

Initial therapy for septic shock?

A

Dopamine

Alfa 1 ^ beta 1

50
Q

Which drug causes livedo reticularis (purplish red mottling)

A

Amantadine: local release of NE

51
Q

Warfarin

A

Inhibit hepatic synthesis of vit K (2,7,9,10,C,S)

52
Q

Scopolamine

A

Antimuscarinic: tachycardia, constipation, urinary retention, dry mouth

53
Q

Lab test for confirmation of Borrelia burgdorferi infection ?

A

Western blot for detection of antibodies

54
Q

Shunt that affects arterial o2 content ?

A

Right to left

55
Q

⬆️AFP

A

Marked ⬆️: hepatocellular ca, germ cell tumors w/yolk sac component

Small ⬆️: GI ^ lung tumors

Prenatal neural tube defects

56
Q

Pinworm: enterobius vermicularis

Treatment ?

A

Mebendazole

57
Q

Patchy infliltrates after lung transplant

Lymphocytes, inflammatory response

A

ACUTE REJECTION: can occur between 2wks-2yrs

58
Q

Nerve injured during radical mastectomy

A

Long thoracic nerve: serratus anterior

59
Q

Low Na
Low plasma osmolarity
Normovolemia

A

Hypothyroidism
SIADH
hypoadrenalism
Diuretic use

60
Q

Blood volume formula

A

BV= Plasma volume/(1 - fractional hematocrit)

FH=40% ➡️0.4

61
Q

Alfa 1 antitrypsin

Emphysema ?

62
Q

Aorticopulmonary septum

A

Neural crest cells

63
Q

Axilary nerve innervates ?

A

Teres minor
Deltoid
Triceps brachii

64
Q

Cremasteric reflex

65
Q

Digoxin

A 
HF(⬆️contractility)
Atrial fibrillation (⬇️conduction AV node)
66
Q

High levels can be measured within an hour after exercise

67
Q

Conotruncal ridges participates in the formation of

A

The membranous IV septum

Aorticopulmonary septum

68
Q

BB contraindicated in angina

A

Pindolol: it does not ⬇️ myocardial O2 demand

ISA

69
Q

⬆️DBP

A

⬆️SVR: alfa 1

70
Q

Refractory Crohn disease

A

Infliximab

Monoclonal ab against TNF

71
Q

OH withdrawal (4)

A

Minor tremulousness
Anxiety
Headache
Palpitations

72
Q

Delirium tremens

A 
Hallucinations 
Tachycardia 
Disorientation
HTN 
Fever 
Agitation 
Diaphoresis 
Grand mal seizures
73
Q

ACEI contraindication ?

A

Renovascular HTN

74
Q

3rd pharyngeal arch

A

Stylopharyngeus muscle

75
Q

Best evidence that the anemia is due to a primary deficiency of B12 ?

A

⬆️ methylmalonate

76
Q

Acyclovir

Mechanism of action ?

A

Inhibit viral DNA polymerase

77
Q

Retroperitoneal organs

A

Ascending ^ descending colon
Duodenum
Kidneys

78
Q

Pulmonary vascular resistance

Formula ?

A

R= (pulm art pressure - pulm venous pressure)/CO

79
Q

Dopamine antagonist

A

Haloperidol

80
Q

Uncontrolled HTN + BPH

treatment ?

A

Alfa 1 receptors blockers
Prazosin
Terazosin
Doxazosin

81
Q

Oxygen consumption

Fick equation

A

Oxygen consumption = CO * (arterial O2 content - venous O2 content)

82
Q

Drugs that inhibit P-450 system ?

A

Ketoconazole
Cimetidine
Isoniazid

83
Q

Drugs that induce P-450 system?

A

Barbiturates
CBZ
Phenytoin
Rifampin

84
Q

Neoplastic diseases caused by virus

A 
Adult T-cell leukemia/lymphoma➡️HTLV-1
Burkitt lymphoma➡️EBV
Hepatocellular carcinoma➡️HBV
cervical ca➡️HPV
Kaposi sarcoma➡️HIV
85
Q

Inulin

PAH

A

Inulin: freely filtered, 🚫secreted, 🚫 reabsorbed
PAH: freely filtered ^ secreted, 🚫 reabsorbed

86
Q

Competitive inhibitor

87
Q

Hemochromatosis

A

HLA-A3 allele
Iron
Prussian blue

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