exam2 Flashcards
cow fetal death of less than 8 weeks
early embryonic death
fetal death greater than 260 days in cows
still birth
intervention level of abortions in cow herd
> 5%
1 diagnosis of abortions in cows
unknown
tissue submissions for abortion dx in cows
placenta
fetus
maternal blood
cow ate old silage and then aborted baby in last trimester
fetus was all autolysed
listeria
bacterial cause of abortion which shows a clinically ill mamma cow
listeria
predilection site for lepto
renal tubules
T/F
all serovars of leptospirosis are zoonotic
true
treatment for outbreak of lepto
long term tetracyclines
when to collect cow urine to test for lepto
2nd pee after furosemide
zoonotic form of brucella abortus
undulant fever
T/F
brucella abortus is commonly transmitted via coitus
false
what follows abortion from brucella abortus
metritis and retained fetal membranes
tissues needed to diagnose brucella abortus
fetus lungs and abomasum
dx requires virus isolation
sign on fetus that brucella was the cause of the abortion
moroccan leather placentitis
dry thickened and cracked intercotyledon areas
vaccination for bruclla
heifers
What is the treatment for brucella and how do you handle it
reportable dz
no tx cull cow
also known as vibrio
campylobacter foetus veneralis
*obligate parasite of bovine gentalia
campylobacter foetus veneralis
transmission and pathogenesis
coitus or AI fomites
causes early embryonic death
campylobacter foetus veneralis
clinical signs in cow and in bull
cow - delayed return to estrus. will return to normal
bull - no signs. cull bull
GI tract inhabitant of cattle – not venereally transmitted – causes sporadic abortions in cattle
c. fetus fetus/c fetus jejunum
where does tritichomonas fetus like to live
preputial crypts - expecially in older bulls
transmitted by coitus – bulls are primary reservoir
what type of histogram will you see for diagnosing tritrichomonas
reverse stair step
dogs are the definitive host –
nespora caninum
diagnose neospora caninum
IHC of fetal tissues and placenta
what is the other name for bovine herpes virus 1
infectious bovine rhinotracheitis
dx bovine herpes virus 1
intranuclear inclusion bodies on IHC
abortion storms
autolysed foci necrosis on fetus liver
primary source of spreading bovine viral diarrhea viurs
persistently infected cattle
*virus isolation = gold standard dx
how is bluetongue virus transmitted
cuilcoides - to sheep and cows
*causes teratogenesis
only vax for bluetongue/orbivirus are
MLV - could propagate the virus
causes 70% of fungal abortions in cattle
aspergillus fumigatus
3 teratogenic plants
poison hemlock - conium maculatum
tobacco - nicotinia gluaca
lupines - anagryine
first green forage to appear, when ingested between day 50 and 75 of gestation, it will cause crooked calf syndrome
poison hemlock
causes severe spinal and limb deformities in cattle as well as cleft lips
lupines
T/F
lupines are teratogenic to cattle and small ruminants
false - not small ruminants
tx by rotation of pasture
when ingested between day 50-75 of gestation will cause curvature of the spine and forelimb arthrogryposis
tobaccos
causes more economic losses than any other plant
locoweed
toxin in locoweed
swainsonine
toxin in ponderosa pine
isocupressic acid
what does ponderosa pine do
vasoconstriction at caruncles
hemorrhagic placenta
abortions
plant that produces toxic alkaloids and causes peripheral vasoconstriction
fescue – leads to summer slump
what are those oats wheat corn sudan grass johnson grass
nitrate producing plants – seen in drought periods
test hay, >1% is toxic
test ocular fluid or aborted fetus
methemoglobinemia in cows
fetal hypoxia and late term abortions
insecticides that have a harmful effect on bull fertility
pyrethroids
accumulation of allantoic fluid during last trimester
hydrallantois
inducing an abortion in a cow at day 5 - 150 of gestation
single injection of pgf
abortion in 5-7 days and estrus 3-5 later
inducing an abortion in a cow at day 150 - 240 of gestation
must remove ovarian and placental p4
25mg DEX and 25mg Lutalyse
induced parturition
25 mg dex and 25mg pgf = delivery in 40 hours
4 parts of a bull soundness exam
- physical exam
- minimum scrotal circumference based on age
- minimum progressive motility of 30%
- minimum of 70% morpholocially normal cells
T/F
test mating is included in a bull soundness exam
false
T/F
bull scrotum should be pendulous
true
a 2 yr old cow should have a scrotal circumference of what min to pass the BSE
34cm
t/F
on rectal exam of a bull, you should be able to place your finger into the inguinal ring
false - indicates hernia
minimum acccepted cow sperm motility
30%
semen is stained with __ to assess morphology
eosin-nigrosin
normal = 70%
primary sperm abnormality
originates in testes during spermatogenesis
production problem
involves head and middle
secondary sperm abnormality
originates in the tail/epidiymis
transit defect
morphological defect that can be compensated for by additional sperm
compensable
abnormality that will express a decrease in fertility at the 1% level of occurrence
non-compensable
body hair accumulation on the penis
penile hair rings
incomplete separation of penis and prepuce
persistent frenulum
heritable
tx - excision
penile warts
young bulls with bovine papilloma virus from homosexual riding
- can cause hesitancy to breed or scant hemorrhage post coitus
penile hematoma - sexual rest for __ days
60
S shaped penile deviation
apical ligament is too shorts
T/F
epididymitis is usually unilateral
true
when sheep and goats come into puberty
60% body weight
*short day fall breeders
ewe estrous cycle
17 dys
ewe estrus period
30 hours
ewe gestation
147 days
ewe p4 production
placenta
doe estrous cycle
21 days
doe estrus period
36 hours
doe gestation
150 days
doe p4 production
CL dependents
does estrus period behavior
from when the stand to be mounted til they refuse
shorten diestrus phase
prostaglandin
what is flushing in a ewe
increasing nutrients 2-3 weeks prior to breeding
mimic diestrus phase
progesterone
synchronize follicular wave
gnrh
CIDR in sheep and goats
12-14 days
T/F
prostaglandins only work during the breeding season
true – must have a CL
give 2 doses 9 days apart in sheep
what is involved in the maternal recognition of sheep pregnancy
interferon tau
when can a fetal heartbeat be seen on US in sheep
25 days
how to confirm sheep twins
must see both on the same screen
what is “bagging up”
after 100 days pregnant in sheep udders start to develop
why are sleeves and gloves so important when pulling a lamb or goat in dystocia
a lot of zoonotic diseases in sheep cause abortions
heritable trait in sheep where the cervix fails to completely dilate
ringwomb
sheep/goat uterine involution takes how long
30 days
sheep/goat uterine prolapse tx
elevate hind legs to aid in reduction
placenta should be expelled by how many hours in goat/sheep
6 hours – if not give pgf2a or oxytocin to help
causes cyclops babies if ingested between day 12-14 of gestation
veratrum californicum – skunk cabbage
can lower spermatogenesis and lead to ram infertility if ingested
locoweed
estrogen producing plant that causes vaginal prolapse in sheep and goats
subterranean clover and alfalfa
prolonged luteal phase in goats that leads to a retained CL so the uterus fills up with hyperechoic fluid
cloud burst – pseudopregnancy
tx- pgf2a
clinical signs of blue tongue in sheep
swollen face ear tongue
coronary band ulceration/lameness
mouth and nose ulcerations - call authorities
causes hairy shaker lamb
border disease virus
border disease virus transmission and signs
oral transmission – infects fecal placental unit
can cause persistently infected animals
hydrencephaly and cerebellar hypoplasia
disease transmitted by mosquitoes in SW US that causes still births, fevers, arthrogryposis and brachygnathia
cache valley disease
virus in africa that is transmitted by mosquitos and culicoides that causes arthrogryposis and hydrocephalus
akabane virus
brucella in goats that causes abortion
meletensis
brucella in sheep causes epididymitis in rams
ovis
most significant cause of abortion in sheep
campylobacter fetus fetus zoonotic transmitted in fetal fluids hepatic necrosis/donut lesions in liver tx tetracyclines or vaccinate before breeding
most important cause of abortion in goats
chlamydophila abortus – zoonotic
also enzootic abortion of ewes
nectrotic placentitis - late term abortions
histopath for chlamydophila abortus
zeil nelson stain
“Q fever”
coxiella burnetii
obligate intracellular rickettsia
suclinical + abortions
tx tetracyclines
T/F
intercotyledonary areas in aborted fetuses from toxiplasma gondii in sheep and goats will be normal
true – cotyledons will have yellow necrosis foci though
T/F
do not breed polled goats
true
**associated with intersex
use ____ to measure scrotal circumference in buck or ram
yellow tape
surrounds ovary of the bitch
adipose tissue
ability of hypothalamic neurons to produce significant gnrh
puberty
initiation of overt activity in canine
proestrus
in canine time from one estrus to the next
about 7 months
inestrus period
amount of progesterone that indicates LH peak in bitch
2 ng/ml
amount of progesterone that indicates ovulation starting in the bitch
5 ng/ml
amount of progesterone that confirms bitch ovulation
> 15 ng/ml
**rise in P4 of 3 ng/ml in 24 hours
**failure to confirm is a common mistake
when to breed for natural or shipped canine semen
when to breed for frozen canine semen
shipped/natural : 48 - 96 hours after ovulation
frozen: 72 hours after ovulation
embryos remain in oviduct __ days post ovulation
9 - 10 days
canine oocyes are good for up to ___ hours post ovulation
108 hours
more definitive than progesterone —
LH assays
3 fractions of canine sperm
pre sperm
sperm rich
prostatic portion
normal dog should have > __ % progressively motile sperm
80%
sperm concentration dog
4-400 x 10^6 / ml
methods to breed dog to ensure sperm goes into uterus
transcervical or surgical (midline laparotomy)
2 males breed same female during a single estrus
superfecundation
1 female gets pregnant 2x - diff age fetuses in her
superfetation
neonate puppy heartbeats need to be above `
200bpm
ultrasound can detect puppy at what day
22 - 25
pregnant puppy can be detected using relaxin asssay at what days
21 - 28
where does relaxin come from
placenta
drops 24 hours prior to dog whelping
body temp – indicates drop in progesterone
how to treat fetal wastage
evacuate uterine contents - pgf2a
1 cause for canine dystocia
primary uterine inertia – P4 < 2 nb/ml = no labor
4 signs of canine parturtion
- progesterone falls rapidly to <2 ng/ml
- transient drop in temp
- milk evident in glands 1-7 days prior
- nesting behavior 12-24 hours prior
green black discharge in canine pregnancies
uteroverdin – placental marginal hematoma = provides fetus with iron
intervention criteria in dog parturtition
active contractions >1 hour
rest periods > 4 hours
black thick discharge without fetus
dog placenta
5 layers
zonary endotheliochorial
signal to quit in dam bitch
pressure in glands
puppies are what for the first 2-3 weeks
poikilothermic need to keep them warm day 1-7 85-90* day 8-28 80* day 29+ 70-75*
daily weigh gain for puppy
10% birth weight daily
inflammation of the uterus (endo and myometrium)
metritis
what phase does pyometra occcur
diestral disease - occurs during progesterone pahse of the cycle
cystic endometrial hyperplasia
downregulation of estrogen receptors dur to increasing P4 may be defective so there are prolonged effects of estrogen on the endometrium
can lead to secondary e coli infection and endotoxemia
treatment of choice for both open and closed pyo
ovariohysterectomy - spay
T/F
medical therapy is used in closed pyos only
false - open pyo only
firm tubular mass protruding from the vulva during or following parturition
prolapsed uterus
T/F
galactorrhea is a proestrus condition
FALSE - diestrus
spontaneous flow of milk from the mammary gland unassociated with pregnancy, 2-3 months after estrus
galactorhea
spontaneous development of mammary gland
false pregnancy
2nd most common tumor in the dog
mammary
intact females risk compared to spayed females for developing mammary tumors
7x
is spayed before 1st estrus cycle, risk of malignant mammary tumor is
0.5%
is spayed after 2nd estrus cycle, risk of malignant mammary tumor is
26%
is spayed after 1st estrus cycle, risk of malignant mammary tumor is
8%
persistent uterine bleeding
subinvolution of placental sites (sips)
lesions, histo and treatment for SIPS
erosions in endometrium
multinuclear giant trophoblast cells
self limiting
T/F
any progesterone can masculinize the female fetuses
TRUE – wait until after 45 days pregnancy to supplement to avoud fetus masculizination
angrogenic contraceptive for dogs - not for breeding bitches
mibolerone
drug to decrease unwanted uterine contractions in dog
beta 2 agonist - terbutaline
ovarian remnant syndrome
recurrent estrus after ohe
cytology will show proestrus/estrus
estradiol > 20ng/ml in diestrus
tx - exp lat and remove ovary leftovers
surgery to correct adult dog vaginitis
episioplasty – removal of skin flappage around vulva
screening test for brucella canis
rapid slide agglutination test
what test confirms brucella canis
culture = absolute
causes abortion due to placentitis and orchitis/epididymitis in dogs
brucella canis
if positive result for brucella canis on routine screening ?
do AGID to rule out false positives
if positive for brucella canis and showing clinical signs..
do blood or discharge cultures
if negative for brucella canis on routine screen
no other test needed
if negative for brucella canis but showing clinical signs ?
3 monthly tests are required to rule out false negative..
what test will rule out false positive for brucella canis
agar gel immunodiffusion test (AGID)
T/F
mycoplasma in dogs can be treated using tetracycline
true
temperature sensitive virus that replicates in the oropharynx of dogs
canine herpes virus
what is the time frame for herpes virus to infect a naive bitch to cause issues to the pups
last 3 weeks of pregnancy and first 3 weeks of neonatal life
clinical signs of canine herpes virus
fading puppy syndrome
crying, greenish stool, abdominal pain, high mortality
on necropsy and histopath what are pathognomonic for canine herpes virus
petechial hemorrhage on liver, kidney, lung, spleen
intranuclear inclusion bodies !!!
dog testes descend into the scrotum by when
10 days – both should be there by 16weeks
not considered cryptorchid until 6 months old
testicular torsion tx of choice
bilateral orchidectomy
most common tumor after skin tumors in male dogs
testicular tumors
sertoli = 44%
leydig/interstial cell = 25%
both cause paraneoplastic syndrome
T/F
tumor that causes dog to have hyperestogenism behaviors produces estrogen
FALSE -
T/F
TVT is a cause of azoospermia
false
TVT is treatable with what chemo drug
vincristine
dog with red pea appearance at tip of penis
urethral prolapse – do a urtheropexy
persistent erection
priapism
constipation and flat ribbon feces in male dog
benign prostatic hyperplasia
on a prostatic wash how can you differentiate benign from malignant tumors
benign - uniform cells
tumor - variable cells
septic - inflammatory cells
most common cause of prostatitis
e coli
acute bacterial prostatitis
fever depression pain on rectal palp pyuria neutrophilia
may occur along with BHP
chronic bacterial prostatitis
recurrent UTIs and concurrent BHP
prostate adenocarcinoma
poor appetite weight loss hind limb weakness
carcinoma cells in urine sediment
protatitis and paraprostatic cyst
palpable abdominal cyst mass filled with yello orange fluid
estrus in a cat
vocal
3-16 days
high estrogen
cat copulation - needs neck bit
period when queen was not mated
post - estrus
8-10 days
cat gestation
65 days
camelid luteal phase
short - 9 days
camelid luteolysis
left horn/ side control is ipsilateral
mating in camelids
occurs in sternal recumbency and lasts 25-45 minutes
T/F
>95% of gestation in a camelid is on the right uterine horn
false – LEFT
camelid gestation length
11.5 months
induces the pre-ovulatory LH surge in camelids
ovulation inducing factor
phase when female camelid is non receptive and does not accept mating
luteal phase
fourth membrane cria are born with covering them
epidermal membrane - provides lubrication