Exam II Flashcards
Myasthenia Gravis patho
Autoimmune - acetylcholine receptors in muscle = nerve impulse not transmitted
Multiple Sclerosis patho
Autoimmune - mylein sheath (CNS so does not regenerate)
Guillian Barre patho
Autoimmune - myelin sheath destroyed (PNS so regenerates = recovery)
Amyotrophic Lateral Sclerosis patho
Autoimmune - muscle atrophy from loss of spinal cord nerves = scar tissue, motor neurons
Myasthenia Gravis S&S
Early - facial / occular, chewing and swallowing difficulty, diplopia - double vision, ptosis - drooping of eyelids
Late - limb weakness, general muscle weakness, respiratory impairment
Multiple Sclerosis S&S
Early - nystagmus - involuntary eye movement, fatigue, spasticity
Late - motor and sensory impairments in trunk and limbs, numbness and weakness
symptoms come and go, onset gradual / chronic
Guillian Barre S&S
Ascending - lower extremity paresthesia, paresis to quadreplegia with 50% respiratory compromise, does not affect LOC
Descending - eye, facial and jaw muscle weakness, diplopia, dysphagia
sudden onset, acute, 3 stages
acute phase - onset, ends when no further deterioration 1-4 weeks
plateau phase - little change, several days to 2 weeks
recovery phase - remyelination and axonal regeneration 4-6 months
Amyotrophic Lateral Sclerosis S&S
Early - fatigue, dysphagia & dysarthria - difficulty articulating, extremity weakness
Late - flacid quadreplegia, atrophy extremities, respiratory impairment
gradual onset - no cure
Myasthenia Gravis diagnostics
AChR antibodies, thyroid function tests, Tensilon Test, EMG - repetitive nerve stimulation, pattern of response, serum blood test - acetylcholine receptor antibody
Multiple Sclerosis diagnostics
lumbar puncture - detect oligoclonal bands, CSF, MRI - plaques in brain, nerve sheath demyelination, CT
Guillian Barre diagnostics
Lumbar puncture, Leukocytosis, EMG, MRI, CT
Amyotrophic Lateral Sclerosis diagnostics
Elevated CK, muscle biopsy
Myasthenia Gravis nursing priorities
Risk for ineffective breathing pattern, activity intolerance related to fatigue / muscle weakness, self care deficit, deficient knowledge
Multiple Sclerosis nursing priorities
fatigue, impaired physical mobility, urinary retention, constipation, disturbed sensory perception - visual, deficient knowledge
Guillian Barre nursing priorities
airway, cardiac, acute pain, impaired physical mobility, self care deficit, risk for aspiration
Amyotrophic Lateral Sclerosis nursing priorities
speech therapy, dietician, hospice, advance directives