Exam II Flashcards
risks associated with a thoracic epidural anesthetic.
- Because of the proximity to cardiac accelerator fibers, smaller bolus doses of local anesthetic should be used and response checked carefully before redosing to prevent large drops in heart rate or blood pressure.
- hypotension can occur in nearly all patients with a high thoracic epidural blockade.
Identify why a thoracic epidural is technically more difficult to insert.
- Spinous processes are more angled
- Spinal canal is closer to the skin (shallow)
- there is a greater incidence of false loss of resistance in the midline thoracic approach
S/S of LA toxicity?
- Circumoral numbness (numbness ot the tongue or lips)
- Metalic taste
- tinnitus
- Lightheaded, Slurred speech, Visual Disturbances
- Muscle twitching
- Vertigo
- Seizures soon afterwards and unconsciousness
- CNS depression and Coma
- Respiratory Arrest
- Cardiovascular collapse
Why are opioids mixed with LA’s in epidurals?
They increase the duration of the sensory block, but not the motor block.
What are side effects of opioid given in epidurals?
Resp depression N&V Pruritis Urinary Retention CNS effects (sedation, dysphoria)
Which is more hydrophillic Morphine or Fentanyl and what effects does this have?
Morphine is more hydrophillic (longer duration)
Fentanyl is hydrophobic (shorter duration is epidural space)
What is the duration and dosing for Fentanyl in epidurals?
Bolus dose= 50-100mcg
Continuous= 1-2mcg/ml added to LA
Duration= 2-6 hrs
What is the duration and dosing for Morphine in epidurals?
Bolus= 2-5
Duration=12-24 hrs
Why should extra caution be used when morphine is administered in epidural (spinal also)?
Can be associated with delayed biphasic resp depression
- Early depression from venous absorption
- Late depression from CSF absorption and spread to medullary centers in brain
What does Clonidine do when added to epidural?
Prolongs sensory but not motor block
What is the dose for clonidine in an epidural?
150-300mcg
What does the addition of Epinephrine do when added to epidural?
prolongs both sensory and motor for short and intermediate LA’s
What is the dose for Epinephrine to be added to epidural?
5mcg/ml (1:200,000)
Why will epinephrine in low doses cause more of a drop in MAP?
due to beta 2 vasodilation
What does the addition of bicarb to to LA?
Speeds onset
What is the dose of Bicarb for epidurals?
0.1mEq/ml
Identify the differences in motor, sympathetic, and sensory blockade between SABs and epidurals?
- Spinals have a more rapid onset than epidurals
- Spinals sensory and motor block quality is better
- Epidurals will have less hypotension
Sympathetic 2 above and Motor 2 below sensory for both SAB’s and epidurals
How long should NSAIDs and aspirin be held before Regional anesthesia
No need to hold. do not increase hematoma risk, assuming the pt does not have any coagulopathy
How long should Herbals such as ginko, garlic, ginseng, and fish oil be held before Regional anesthesia
recommended to d/c for 1 week, but no research on this
How long should low dose heparin (Lovenox) be held before and after Regional anesthesia
hold for 12 hours prior to a block. (Wait 12 hrs) before inserting a SAB). Do not remove a epidural catheter for 12 hours after dose of lovenox. Do not restart lovenox for 12 hours after removing
How long should low dose heparin (unfractionated/Sub-Q) be held before and after Regional anesthesia
Wait to do a block for 2 hours after the patient was dosed. Get a PTT to confirm. Do not restart heparin for 2 hours after SAB. If a epidural catheter needs to be removed, wait 2 hours after last dose
What are the recomendations for coumadin levels prior SAB insertion?
INR < 1.3 = safe
INR > 1.5 = NO!
INR 1.3 -1.5 = must weigh the risk vs. benefits
What are the recomendations for platlet levels prior SAB insertion?
Platelets > 100,000 = OK
Platelets < 50,000 = NO!
Platelets 50,000 -100,000 = weigh risks vs. benefits, but NOT recommended
How long should Plavix and Ticlid be held before and after Regional anesthesia
Plavix- d/c for 7 days
Ticlid- d/c for 14 days