Exam I Flashcards

1
Q

IL- 1

A
  • T cell development
  • B cell development
  • E-selectin expression
  • Inflammation
  • Fever
  • APP
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2
Q

IL-2

A

T cell development

Aka: T cell growth factor

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3
Q

IL-6

A
  • T cell development

- B cell development

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4
Q

IL-7

A
  • T cell development

- B cell development

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5
Q

IFN - alpha and beta

A

Antiviral activities

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6
Q

TNF

A
  • E-selectin expression
  • Inflammation
  • Fever
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7
Q

CCL/MCP-1

A

Leukocyte recruitment

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8
Q

CCL5

A

Mixed leukocyte, monocyte recruitment

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9
Q

CCL19/MIP-3beta

A

T cell + DC migration to parafollicular LNs

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10
Q

CCL21/SLC

A

T cell + DC migration to parafollicular LNs

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11
Q

CXCL8/IL-8

A

Neutrophil recruitment

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12
Q

CXCL10/IP-10

A

Effector T cell recruitment

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13
Q

CXCL12/SDF-1alphabeta

A

Homing of naive B cells into LNs

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14
Q

CXCL13/BCA-1

A

B cell migration into follicle

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15
Q

CCR7

A

Activation of integrins + chemokines is when CCL19/CCL21 binds

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16
Q

IFN-gamma

A

Macrophage activation

17
Q

IL-12

A

IFN-gamma production by NK + T cells

18
Q

IL-15

A

Proliferation of NK cells

19
Q

IL-1beta

A

Inflammation

20
Q

IL-18

A

Inflammation

21
Q

IL-4

A

B cell proliferation

22
Q

TNF-alpha

A

Inflammation

23
Q

IL-10

A

Control of inflammation

24
Q

TGF-beta

A

Control of inflammation

25
Q

IL-5

A

B cell proliferation

26
Q

Abs from IFN-gamma

A
  • IgG2a

- IgG3

27
Q

Abs from TGF-beta

A
  • IgA

- IgG2b

28
Q

Abs from IL-4

A
  • IgE

- IgG1

29
Q

Abs from IL-2, IL-4, IL-5

A

IgM