Exam I Flashcards
IL- 1
- T cell development
- B cell development
- E-selectin expression
- Inflammation
- Fever
- APP
IL-2
T cell development
Aka: T cell growth factor
IL-6
- T cell development
- B cell development
IL-7
- T cell development
- B cell development
IFN - alpha and beta
Antiviral activities
TNF
- E-selectin expression
- Inflammation
- Fever
CCL/MCP-1
Leukocyte recruitment
CCL5
Mixed leukocyte, monocyte recruitment
CCL19/MIP-3beta
T cell + DC migration to parafollicular LNs
CCL21/SLC
T cell + DC migration to parafollicular LNs
CXCL8/IL-8
Neutrophil recruitment
CXCL10/IP-10
Effector T cell recruitment
CXCL12/SDF-1alphabeta
Homing of naive B cells into LNs
CXCL13/BCA-1
B cell migration into follicle
CCR7
Activation of integrins + chemokines is when CCL19/CCL21 binds
IFN-gamma
Macrophage activation
IL-12
IFN-gamma production by NK + T cells
IL-15
Proliferation of NK cells
IL-1beta
Inflammation
IL-18
Inflammation
IL-4
B cell proliferation
TNF-alpha
Inflammation
IL-10
Control of inflammation
TGF-beta
Control of inflammation
IL-5
B cell proliferation
Abs from IFN-gamma
- IgG2a
- IgG3
Abs from TGF-beta
- IgA
- IgG2b
Abs from IL-4
- IgE
- IgG1
Abs from IL-2, IL-4, IL-5
IgM
