exam 6

Question 1

hodgkins lymphomas have

Answer 1

reed sternberg cells, which makes it much more serious

Question 2

lymphoma is

Answer 2

an idiopathic malignancy of the lymph system

viruses, carcinogens, smoking, genetics, immunocompromised (AIDs/transplants)

Question 3

Hodgkins is

Answer 3

more treatable with radiation and chemo

alopecia

Question 4

patients with lymphoma will take

Answer 4

immunosuppressants to kill of the WBC and give your body a “fresh start”

Question 5

normal amount of blast cells in the bone marrow

Answer 5

1-2%

Question 6

amount of blast cells of someone with leukemia

Answer 6

20% or higher
the blasts will “crowd out” of the bone marrow
high or low or normal wbc

Question 7

myeloid stem cells

Answer 7

Positive myelopyroxidase

Question 8

lymphoblastic stem cells

Answer 8

Positive TdT

B or T cells

Question 9

what type of alterations to the CBC occur in leukemia

Answer 9

Panocytopenia

Question 10

clinical manifestations of acute myeloid leukemia

Answer 10

Develops without warning
Symptoms develop over a few weeks
Fever and infection from neutropenia
Weakness, fatigue, dyspnea on exertion an pallor from anemia
Petechiae, ecchymosis and bleeding from thrombocytopenia
The proliferation of leukemic cells within organs leads to additional symptoms of pain from enlarged liver or spleen, hyperplasia of the gums and bone pain** from expansion of marrow
Petechiae are common

Question 11

medical management of Aml

Answer 11

Neupogen
PRBC
Platlets
Chemotherapy- given in large dosages this helps prevent a relapse

Question 12

what is chronic myeloid leukemia?

Answer 12

the same as acute over a long period of time
presence of chromosome 22 or philideaphea chromosome
life expectancy 5+ years
in men 30-50

Question 13

clinical manifestations of Chronic myeloid leukemia

Answer 13

leukocyte count can exceed 100,00

leukocyte statis in lungs of other parts of the body, can cause shortness of breath

Question 14

Acute lymphocytic leukemia

Answer 14

common in young boys peak age is 4yo

after 50 chances increase

Question 15

clinical manifestations of ALL

Answer 15

panocytopenia
high or low WBC but they are immature
enlarged liver or spleen and bone pain
CNS is a frequent site for leukemic cells, nerve palsies and head ache s
patients may experience nerve palsies or H/A and vomiting because of menigeal involvement
pain in breasts and testies

Question 16

main difference between ALL and AML**

Answer 16

CNS invasion

Question 17

dexamethasone is given to leukemia patients because

Answer 17

it is toxic to lymphoid cells