Exam 4_ABID & Compatibility Flashcards
Compatibility Testing
involves all the steps in the identification and testing of a donor unit and a proposed recipients blood
Crossmatching
part of compatibility testing
-involves mixing donor RBC and recipient serum or plasma
-no agglutination or hemolysis indicates compatibility
-agglutination or hemolysis indicates incompatibility (positive result)
What is the purpose of crossmatching?
-double check of ABO ERRORS
-PROVIDES a second means of detecting Antibodies
according to AABB stds: “shall use methods that demonstrate ABO incompatibility and clinically significant antibodies to red cells antigens and shall include an antiglobulin phase” so type and screen show ABO…
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What are the two serologic crossmatching?
-IS cross match
-Extended Crossmatch
What is IS Crossmatch?
performed when the recipient has no evidence of an antibody in the current sample or in pt hx
-recipient serum and donor RBC suspension are mixed and immediately centrifuged
-Fullfills AABB stds for detecting ABO incompatability
What is an extended crossmatch?
What can cause a positive result in the serologic crossmatch
- ## incorrect ABO grouping of the pt or donor-
What is alloantibody?
What are warm-reactive autoantibody?
What are limitations to crossmatching?
Pretransfusion will if performed correctly…
Transfusion Request Form
-oral, written, electronic,
-two identifiers:
-blood is a drug and requires physician prescription
-special neds: CMV negative…
Specimens: general pts
Specimens: neonates
Specimens: Elective Surgery pts