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NUR123 > Exam 4 Pharma > Flashcards

Exam 4 Pharma Flashcards

1
Q

UTI Abx - Floroquinolone

A

Uncomplicated UTI: Rhabdo, Rash, GI, C diff, seizures . 1 hr pre or 2 hr post meal

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2
Q

UTI Abx - Nitrofurantoin

A

Not for GFR < 50

Periph neuropathy

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3
Q

UTI Abx- Amoxicillin

A

Allergy

Highly resistant

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4
Q

UTI Analgesic - Phenazopyridine

A

Dark orange urine

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5
Q

Pyelonephritis Abx

A 
TMP-SMX
Ciprofloxacin
gentamicin
3rd generation cephalosporin
Oral or IV
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6
Q

Pyelonephritis NSAID

A

For fever and discomfort

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7
Q

BPH 5-alpha Reductase inhbitors

A

Finasteride, dutasteride
Interfere w/ testosterone to DHT conversion, shrink
Se: low libido and ejaculate, ED

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8
Q

BPH - Alpha Blockers

A

doxazosin, terazosin, tamsulosin

Relax smooth muscle, NOT shrink, helps w/ sx
Se: Ortho hypo, dizzy, retrograde ejac, nasal cong

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9
Q

BPH Herbals

A

Saw Palmetto
Relief, stops conversion
Se: GI, bleeding (stop before surgery)
Better tolerated and as effective

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10
Q

Gout - Anti inflammatories

A

colcichine - it Interferes with the functions of the WBCs in initiating and perpetuating inflammatory response
SE: GI Upset, diarrhea, NV, abd pain, aplastic anemia
Take w/ meals NOT with grapefruit juice

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11
Q

Gout NSAIDS

A

indomethacin

Ibuprofen

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12
Q

Gout Uricosuric

A

Probenecid - inhibits renal absorption of urates and increases excretion, decreases serum uric acid
SE: kidney stones, GI upset, aplastic anemia, flusing. Action decreased by salicylates

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13
Q

Gout combo drug

A

Colbenemid - colchicine + probenecid

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14
Q

Gout Xanthine Oxidase Inhibitors

A

febustat - interrupts purine breakdown

Allopurinol - Prevents uric acid in blood by blocking formation
Se: Increases action of antidiabetic agents, hypotension, hepatitis, bone marrow depression, NV flusing, rash, increases theopyhlline toxicity

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15
Q

Gout ARB

A

Losarten- good for elderly with HTN and gout, promotes excretion

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16
Q

Gout others

A

ASA and Thiazide diuretics- block renal excretion of uric acid

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17
Q

OA Pharma

A

Acetominophen max dose 2600 /day
Topical creams - capsaicin, methyl salicate
NSAIDS - misoprostol w/ GI complications

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18
Q

OA Viscosupplementation

A

hyaluronic acid injection

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19
Q

OA COX 2 Inihbitors

A

celecoxib SE: CV disease and GI distress

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20
Q

RA DMARDS

A

methotrexate- drug of choice, rapid anti inflammatory
SE: myelosuppression, aplastic anemia and GI toxicity, teratogenic
Sulfasalazine
Leflunomide

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21
Q

RA Biologics:

A

Serious Infection risk, no live vaccines
etanercept, adalimumab, infliximab: injectable
SE: bacterial sepsis, invasive fungal infection and TB
Mantoux before tx recommend

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22
Q

RA Antimalarial

A

Hydroxychloroquine
Antiinflammatory works w/ methotrexate
SE: BM Suppression, GI ulcers, infection risk, rashes, alopecia, bladder toxicity

23
Q

RA Sx Treatment

A 
NSAIDs
Glucocorticoids
Antibiotics
Gold Salts
Antidepressants
Sleep aids
24
Q

SLE Pharma

A 
Immunosuppressant - imuran, cyclophosphamide, steroids
NSAIDS
DMARDS
Antimalarial
Anticonvulsants
25
Q

OP Biphosphonates

A

alendronate, risendronate,
ibandronate,
zoledronic acid
SE: GI, ulcers, jaw necrosis

26
Q

OP Selective Estrogen Receptor Modulator SERMs

A

Raloxifene

SE: Increased risk thromboembolism, allergy, chest tightness

27
Q

OP Calcitonin

A

Nasal application

Se: Nasal irritation, flushing, GI, urinary frequency

28
Q

MS Interferons

A

beta 1a

Beta 1b

29
Q

MS Synthetic Immunomodulator

A

glatiramer acetate

30
Q

MS Steroids

A

prednisone, methylprednisone

31
Q

MS Antispasmodics

A

baclofen

32
Q

Parkinsons Dopaminergics

A

Carbidopa/Levadopa - unpredictable, wears on and off, paradoxical intoxication

33
Q

Parkinsons Dopamine agonists

A

bromocriptine

34
Q

Parkinsons Catechol O methyltransferase COMT inhibitors

A

entacapone

35
Q

Parkinsons MAO-B inhibitors

A

rasagiline

36
Q

Parkinsons Anticholinergics

A

benztropine

37
Q

MG Anticholinesterase inhibitors

A

pyridostigmine bromide

38
Q

MG Corticosteroids

A

prednisone

39
Q

MG Tensilon

A

edrophonium

40
Q

Spastic Bladder Anticholinergic

A

propantheline

oxybutynin

41
Q

Spastic BLadder Skeletal muscle relaxants

A

baclofen

42
Q

Flaccid Bladder Cholinergic

A

bethanechol

43
Q

Constipation - bulk forming laxatives

A

polyethylene glycol

Psyllium

44
Q

Constipation - Stool softener

A

docusate sodium

45
Q

Diarrhea - antidiarrheal

A

loperamide

diphenoxylate w/ atropine

46
Q

Diarrhea - anticholinergic

A

propantheline

47
Q

IBD Aminosalycates

A

sulfasalazine
mesalamine
Decrease mild/mod inflammation and MAINTAIN REMISSION
SE: orange urine, photosensitivity (sulfasalazine), decreased urine output, flu like sx

48
Q

IBD Abx and CS

A 
DONT MAINTAIN REMISSION
metronidazole (tx secondary infections)
CS: Prednisone PO
Hydrocortisone IV
budesonide PR
49
Q

IBD Immunosuppressant

A

6-mercaptopurine
azathioprine
methotraxate
MAINTIAIN REMISSION

50
Q

IBD Biologic

A

natizumab
infliximab
MAINTAIN REMISSION

51
Q

Lower GI Saline agent

A

magnesium hydroxide

52
Q

Lower GI stimulant

A

bisacodyl

53
Q

Lower GI Vit B12

A

cobalamin

54
Q

Lower GI chloride channel activator

A

lubiprostone

NUR123 (6 decks)

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