Exam 4 Ilardi Flashcards

1
Q

ADHD DSM-5

A

Six or more symptoms -children up to age 16 or
Five or more for adolescents 17 and older
1. Fails to give close attention to details or makes careless mistakes.
2. Has trouble holding attention on tasks or play activities.
3. Does not seem to listen when spoken to directly.
4. Does not follow through on instructions and fails to finish tasks.
5. Trouble with organization tasks and activities.
6. Avoids, dislikes, or is reluctant to do tasks that require mental effort.
7. Loses things necessary for tasks and activities.
8. Is easily distracted
9. Is forgetful in daily activities.

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2
Q

Hyperfocus

A

Will lock in on something until they reach the top level. Will not be interrupted.

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3
Q

Hyperactivity and Impulsivity DSM-5

A

Six or more symptoms for children up to age 16, or five or more adolescents 17 and older and adults; symptoms have been present for at least 6 months to an extent that is disruptive and inappropriate for the person’s developmental level:
1. Fidgets with or taps hands or feet, or squirms in seat.
2. Leaves seat in situations when remaining seated is expected.
3. Runs about or climbs in situations where it is not appropriate (adolescents or adults may be limited to feeling restless).
4. Unable to play or take part in leisure activities quietly.
5. Is “on the go” acting as if “driven by a motor”
6. Talks excessively
7. Blurts out an answer before a question has been completed
8. Has trouble waiting his/her turn.
9. Interrupts or intrudes on others (e.g., butt into conversations or games)
ADHD diagnosis requires either AD or HD (or both)
Several symptoms present before age 12

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4
Q

ADHD Prevalence

A

~10% of school age population; ~5% of adult population
Gender ratio ~3:1 (male/female)
Only about half of people who have ADHD diagnostic in school have it as an adult

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5
Q

ADHD Causes

A
Heritability ~50% 
Frontal cortex (impulse control, attentional focus, logical sequencing)
Reward/pleasure circuits
Dopamine function (DRD2, DBH genes)
Norepinephrine – helps regulate alertness, mental stamina, attentional focus
Omega03, zinc deficiency
Food additives (elimination diet)
Screen time?
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6
Q

ADHD Treatments

A

•Stimulants (Ritalin/Concerta [methylphenidate], Adderall/Vyvanse, Strattera) [less addictive than benzos but way more highly monitored]
o MTA Study 8-Year Results
o Ritalin quickly metabolized; Adderall slow (half-life 10 hours)
•Cognitive-behavior therapy (CBT), behavior therapy (BT)
•Omega-3
•Exercise
•Light Therapy
•Elimination diet (avoid processed foods)
•Meditation

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7
Q

Hyper Paradox

A

already hyper + stimulant

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8
Q

Major Eating Disorders

A
  • Anorexia nervosa
  • Bulimia nervosa
  • Binge Eating disorder
  • OSFED
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9
Q

Anorexia Nervosa

A
  1. Restricted energy intake -> clinically underweight
  2. Intense fear of becoming “fat” / gaining weight
  3. Disturbance of body image
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10
Q

Anorexia Subtypes

A
  1. Restricting

2. Binge/Purge

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11
Q

Anorexia Nervosa Prevalence

A
  • Lifetime Prevalence ~ 1% female, 0.3% Male
  • 10-15% die of starvation, medical complications, or suicide
  • Prominent medical difficulties include: malnutrition, dry yellow skin, amenorrhea (loss of menstruation), cold sensitivity, slow heartbeat, dehydration, loss of potassium (risk of heart or kidney failure),
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12
Q

Anorexia Co-morbidity

A

• 35% co-morbidity with OCD
oAnorexia is genetically linked with OCD
• Stimulus → Obsessional thoughts → Anxiety → Rituals → [Reduce Anxiety]
• Stimulus (look in the mirror, try on clothes) → Obsessional thoughts (I’m going to get fat) → Anxiety → Rituals (Count calories –hard limit – around 400-600 calories/day) → [Reduce Anxiety]

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13
Q

Bulimia Nervosa

A

A. Recurrent episodes of binge eating (“amount of food that is definitely more than most people would eat”)
B. Sense lack of control
C. Recurrent compensating behavior(s) to prevent weight gain (vomiting, laxative use, diuretics, enemas, exercise)
D. Binges/purges occur at least once a week for 3 months
E. Self-evaluation unduly influences by body shape/weight
F. No diagnosis of anorexia (typically average weight, often slightly overweight)

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14
Q

Bulimia Prevalence

A

• Lifetime Prevalence: ~2% (women), < 1% (men)
• Up to 20% of college-age women may exhibit binge/purge symptoms
G. People with Bulimia are typically not thin (usually a little overweight).
• Have a genetic overlap with addictive disorders

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15
Q

Binge Eating Disorder

A
  1. Recurrent and persistent episodes of binge eating
  2. Binge eating episodes are associated with three (or more) of the following:
    •Eating much more rapidly than normal
    •Eating until feeling uncomfortably full
    •Eating large amounts of food when not feeling physically hungry
    •Eating alone because of being embarrassed by how much one is eating
    •Feeling disgusted with oneself, depressed, or very guilty after overeating
  3. Marked distress regarding binge eating
  4. Absence of regular compensatory behaviors (such as purging).
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16
Q

Substance Dependance

A
  • What we typically think of as “addiction”
  • Involves physiological dependence, tolerance, withdrawal
  • Use is frequent, interferes with functioning, but they can’t stop using
17
Q

Substance Abuse

A
  • Less severe than dependence

* Use is typically sporadic, but causes functional impairment

18
Q

Substance Use Disorder Prevalence

A
  • Nicotine ~ 24% * pure nicotine is not very addictive – it’s everything else mixed with it. Tobacco is insanely addictive.
  • Alcohol ~ 14-17% (20% males; 8% female)
  • Illicit drugs ~ 6-10%
19
Q

What causes addiction?

A
  1. Drugs more reinforcing for some individuals
    A. When addicted, low dopamine responses to everyday highs
    B. Dopamine receptors (D2)
    • Genetics (h~.50)
    • Childhood abuse/trauma/neglect
    • Depression
    • Exercise
    • Social connection
    • Stimulating environment
  2. Toxic metabolites (e.g. acetaldehyde) more “punishing” for some
20
Q

Schizophrenia

A

• Term literally means “split mind” – but doesn’t mean multiple personality
• Bleuler (Swiss psychiatrist) coined term in 1911. Observation of “split” between thoughts & feelings, also between different thoughts These splits are known collectively as formal thought disorder.
• The hallmark of the disorder is psychosis – a split with reality. Delusions and hallucinations are the two varieties of psychosis.
• Language disturbances – e.g., disorganized speech
- is heterogeneous

21
Q

Medical disease model of Schizophrenia

A

Genetic Evidence
• Monozygotic concordance rate about 40-50%
• Dizygotic concordance about 10%
• Heritability (H): 50-60% (best estimates)
• Adoption studies – interaction of genetics & family environment
B. Disordered Brain Development
• Maternal influenza during 2nd trimester of pregnancy
• Maternal malnutrition
• Low birth-weight
• Subtle neurological deficits (eye-tracking, motor incoordination)
• Excessive neural pruning during late adolescence

22
Q

Hypofrontality

A
  • Dorsolateral PFC – logical thinking, reality testing, working memory
  • Ventromedial PFC – self awareness, consciousness, emotion processing
23
Q

Dopamine Hypothesis (increased cerebral dopamine activity)

A
  • All anti-psychotic drugs block DA transmission
  • Amphetamines increase DA transmission (and cause psychosis at high doses)
  • Overall, model helpful but too simplistic. DA has complex interaction with other transmitters and peptides in brain.
  • Important new findings links DA with loss of glutamate NMDA receptors
24
Q

Disordered Lipid Metabolism in Brain

A
  • Excessive breakdown (oxidation) of lipids in neuron membrane
  • Reduced transport of lipids into neuron membrane
  • EPA from Omega-3 helps correct both problems
25
Q

Medical Treatment

A
  • Neuroleptic drugs (Haldol, Thorazine, Melloril, etc.)
  • Novel antipsychotic drugs (Clozaril, Seroquel, Zyprexa, Geodon, Risperdol, Abilify*)
  • 80-90% achieve some short-term response (reduced psychosis)
  • only 5-15% recover and stay full remitted for a decade
  • Side Effects: weight gain, sedation, motor spasms, brain shrinkage
26
Q

Family Therapy

A
  • “Expressed Emotion” from family (critical and emotionally overinvolved)
  • Reduces relapse risk
27
Q

Cognitive-Behavioral Model

A
  • Focus on specific behaviors associated with schizophrenia

* Moderately successful for functional deficits, not for psychoses

28
Q

Histrionic

A

Crave attention, loud, dress provocatively, “drama queens”, extreme but shallow emotional reactions (Ex. Madonna, Dennis Rodman, Reality TV)

29
Q

Narcissistic

A

sense of entitlement (think they deserve “special” treatment); self-absorbed, crave admiration, grandiosity (Drama of the Gifted Child) (Ex: Kanye, certain unnamed politicians, movie stars)
• Epically egotistical and insecure at the same time – feel they are so special, but have pressure to be perfect (need to be uniquely wonderful)

30
Q

Borderline

A
intense emotions (highly reactive), self-mutilation, extreme black-and-white thinking (love/hate relationships), intense fear abandonment, impulsive, confused self-image (Linehan’s Dialectical Behavior Therapy)
•Tend to have a genetic wiring so their amygdala is super active. Mixed with mistreatment (sexual or emotional abuse) (Core is invalidation)
31
Q

Anti-social

A

violate other’s rights, violent behavior, lack of remorse/empathy, violate social norms, impulsive (Hare: Psychopathy Checklist), oxytocin
• Majority of people in state penitentiary have this
• Psychopaths are sometime criminal (usually just manipulate people) – two things wrong with the brain: no release of oxytocin when interacting with people & no receptors for oxytocin in the reward center of the brain.
• Anti-social are often criminal (gang members, are cruel to those they don’t care about, but care about those they love)

32
Q

Obsessive-Compulsive

A

perfectionistic, unrelenting standards can’t delegate, “anal” sometimes major procrastinators (Steve Jobs)

33
Q

Dependent

A

feel like can’t live or function without significant other, clingy, often in abusive relationships, extremely poor self-image
• Often end up in abusive relationships

34
Q

Avoidant

A

chronic social anxiety, anxious about negative evaluation by others in social situations, feel like they’re ugly/uninteresting/undesirable, intensely shy, unwilling to open up unless certain of being liked (Michael Jackson)

35
Q

Jeffrey Young

A

schema-based model of personality disorders (self-help book: Reinventing Your Life)

36
Q

Delusions

A

beliefs that don’t conform with reality

37
Q

Hallucinations

A

perceptions that don’t conform with reality