Exam 4 Drugs Flashcards
- Used for dimentia
- Medical food
- Must stay in fridge for up to 24 hours
Axona
- Claims “imporved aspects of cognitive function over a 90 day period”
- EXPENSIVE
- 1 capsule/day
- Prevagen (apoaequorin)
- Shown to decrease aggression/agitation
- Aromatherapy
- Lemon balm
- Lavender
- Tea Tree Oil
- Key for caregivers
- Support group for dementia
- Alzheimer’s association
- Not recommended for anxiety
- Most studied herb for depression
- Major drug interactions
- 300mg TID
St. John’s Wort
- Dietary synthetic supplement for depression maybe anxiety
- Likely safe
- Peak effect within 2 weeks
- 1600-3000mg/day
Same
- Possibly effective for depression
- Likely safe
- Anti-platelet activity
- 30 mg daily
- Takes 6 - 8 weeks to be effective
Saffron Spice
- Sedative for restlessness/anxiety
- Likely safe
- 150mg daily
- Not the best trials
- Only take for four weeks
Valerian
- Most imporvement in women and younger adults
- Maybe effective in GAD
- Placebo is better
- Inhibitor of CYPs
- 250mg/day
- 3 week use
Kava
- For depression
- 15mg PO dialy
- Really just a multivitamin
- Medical food
Deplin
What are the exclusions to self treatment for tobacco cessation?
- Serious heart disease
- High blood pressure not controlled with medications
- Pregnant/Breastfeeding
- Active peptic ulcer disease (PUD)
What age excludes a patient to self treatment for tobacco cessation?
< 18 years old
- Nicotine replacement gum
- TTFC < 30 minutes after waking = 4mg
- TTFC > 30 minutes after waking = 2mg
- Max 24pieces/day
- Week 1-6: 1 piece q 1-2 hours while awake
- Week 7-9: 1 piece q 2-4 hours while awake
- Week 10-12: 1 piece q 4-8 hours while awake
- Sugar free
Nicotine polacrilex gum (Nicorette)
- Nicotine replacement lozenge
- TTFC < 30 minutes after waking = 4mg
- TTFC > 30 minutes after waking = 2mg
- Max 20 lozenges/day
- Week 1-6: 1 lozenge q 1-2 hours while awake
- Week 7-9: 1 lozenge q 2-4 hours while awake
- Week 10-12: 1 lozenge q 4-8 hours while awake
- Sugar free
Nicotine polacrilex formulation (Nicorette)
- > 10 cigarettes/day
- 21mg/day x 4-6 weeks then:
- 14mg/day x 2 weeks then:
- 7mg/day x 2 weeks
Nicotine transdermal system (NicoDerm CQ): Step 1, step 2, step 3
- < 10 cigarettes/day
- 14mg/day x 6 weeks
- 7mg/day x 2 weeks
Nicotine transdermal system (NicoDerm CQ): Step 2, step 3
What are the exclusion to self treatment for insomnia?
- < 12 or > 65 years old
- Pregnant
- Frequent nocturnal or early morning awakenings
- Chronic > 3 weeks
- Secondary insomnia
- Insomnia treatment
- Antihistamines (2)
- 25 - 50mg taken 30-60 minutes before bed
- CNS effects
- Diphenhydramine
- Doxylamine
- Alternative medicine for insomnia
- 400-600mg 60 minutes before bed
- Do not use in pregnancy or lactation
Valerian Root
- Insomnia & jet lag treatment
- Insomnia: 3-5mg 30 minutes before bed x 4 weeks
- Jet lag: 0.5-2mg pre-flight and 5mg post-flight up to 4 days
Melatonin
What are the exclusion for treatment of drowsiness/fatigue?
- < 12 years old
- Pregnant or breastfeeding
- Heart disease
- Anxiety disorder
- Chronic fatigue
- No response after 7-10 days of OTC treatment
- Drowsiness/fatigue treatment
- Only FDA approved stimulant
- 100-200mg every 3-4 hours
- DIs: aspirin, theophylline, MAOIs
Caffeine tablets
Non-viable food component that confer health benefits on the host associated with the modulation of the microbiota
Prebiotics
- Resistance to digestion in the upper part of the alimentary tract
- Beneficial effect on host’s health
- Selective stimulation of growth of probiotics
- Stability in various food/feed processing conditions
- Fermentation by intestinal microbiota
Ideal Prebiotic Characteristics