Exam 4

Question 1

What are the main type of channels that contribute to membrane repolarization?

Answer 1

Kv channels

Question 2

What three parts of the cell encode information?

Answer 2

cell bodies, axon hillock and dendrites

Question 3

What function do axons play in information?

Answer 3

they transmit it

Question 4

Spike rate is a function of what?

Answer 4

depolarization current

Question 5

A higher current equals a what?

Answer 5

higher firing rate

Question 6

How is spike rate modulated?

Answer 6

by frequency

Question 7

Some parts of neurons encode stimulus intensity through what?

Answer 7

Firing frequency

Question 8

Dendritic/presynaptic delayed rectifier expression patterns are what?

Answer 8

A type (eg Kv4 of Kv 1.4)

Question 9

Soma/nodes/presynaptic delayed rectifier expression patterns are what?

Answer 9

high voltage activated (eg Kv3)

Question 10

nodes/paranodes delayed rectified expression patterns are what?

Answer 10

low voltage activated (eg Kv1)

Question 11

K-type channels _______ neuron after action potential, allowing A-type chanels to ____ from ______.

Answer 11

hyperpolarize, recover, inactivation

Question 12

A-type channels activate, generating _____ current that _____ neuron depolarizing.

Answer 12

outward; stops

Question 13

A-type channels slowly inactivates, so neuron depolarizes to ____ ____.

Answer 13

spike threshold

Question 14

I(a) or K(a) is ___-_____ current.

Answer 14

transient-outward

Question 15

What K subtypes are A-type?

Answer 15

Kv4s and Kv1.4

Question 16

A type: sensitive or insensitive to voltage?

Answer 16

sensitive

Question 17

A type: fast or slow inactivating?

Answer 17

fast

Question 18

Where are A type channels activated?

Answer 18

at subthreshold voltages AFTER hyperpolarizations

Question 19

slide 18

Answer 19

slide 18