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Pharm exam 4 > Exam 4 > Flashcards

Exam 4 Flashcards

1
Q

Inflammatory response

A

protects the body from injury and pathogens

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2
Q

Hageman Factor

A

factor 12

tissue injury

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3
Q

Kinin System

A

Initiate

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4
Q

Bradykinin

A

Arachidonic- stimulates prostaglandins (stimulate or block inflammation response)
Leukotrienes- vasodilation (healing element) Throbaxanes- extremely potent vasoconstrictor

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5
Q

Corticosteriods

A

Prednisone

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6
Q

Salicylates

A 
Aspirin (Bayer)  (fever blocking), (pain blocking)
Excedrin Migraine  (Ringing in ears)
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7
Q

Salicylates Prototype

A

Aspirin- Anti inflammatory, anti pain (mild to moderate), anti pyretic, anti platelet

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8
Q

A person who does not respond to one salicylate may respond to a different one? True or False

A

True

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9
Q

Propionic Acids

A

Ibuprofen most common OTC

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10
Q

Oxicam Derivative

A

Meloxicam (Mobic) chronic inflammation 1Tab

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11
Q

Cyclooxygenase-2 inhibitors

A

Celecoxib (Celebrex) Cox 2 Rheumatoid arthritis helps them function

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12
Q

Acetic Acids

A

Ketoralac (Toradol) Pain IV, PO, only use 3 days cause bleeding

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13
Q

NSAIDS

A

Provide strong anti-inflammatory and analgesic effects
COX 1,2
Ibuprofen (Motrin), Naproxen (Aleve)

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14
Q

NSAIDS drug-drug interaction

A

Loop diuretics, Beta blockers, Lithium toxicity

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15
Q

NSAIDS prototype

A

Ibuprofen (Motrin)

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16
Q

Cyclooxygenase 1 (COX 1)

A

found in many tissues all over the body

converts arachidonic acid to inflammatory prostaglandins

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17
Q

Cyclooxygenase 2 (COX 2)

A

at the site of inflammation
highly caution
celebrex PO only

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18
Q

Acetaminophen

A

most commonly taken

used to treat pain/fever

19
Q

Acetaminophen antidote

A

Acetylsysteine for ppl who over dose inhale or Iv smell like rotten eggs

20
Q

When are NSAIDs contraindicated?

A

Allergy to sulfonamides

21
Q

DMARDs

A

Disease modifying anti-rheumatic drugs

22
Q

Why DMARDs early in the diagnosis

A

before damage to the joints has occurred

23
Q

DMARD drug

A

Etanercept (Enbrel)

24
Q

Adrenal Glands location

A

flattened bodies which sit on top of each kidney

25
Q

Adrenal medulla

A

an inner core part of the SNS

26
Q

Adrenal cortex

A

an outer shell, produces hormones called corticosteroids

27
Q

Types of corticosteroids

A

Androgens (male & female sex hormones)
Glucocorticoids (stimulate an increase in glucose levels for energy)
Mineralocrticoids (affect electrolyte levels and homeostasis)

28
Q

Glucocorticoids prototype

A

Prednisone (replacement therapy)

29
Q

Mineralocorticoids prototype

A

Fludrocortisone (partial replacement therapy)

30
Q

Mineralocorticoids are used to block inflammation and the immune response. What is another example of their use?

A

Stimulate fat deposition

31
Q

The glucocorticoids are used systemically in endocrine disorders. There are multiple contraindications and cautions associated with their use. True or false?

A

True

32
Q

Thyroid Gland

A

Produce two thyroid hormones using iodine found in the diet
Tetraiodothyronine or Levothyroxine T4
Triiodothyronine or Liothyronine T3

33
Q

Hypothyroidism

A 
Levothyroxine (Synthroid)
Thyroid Desiccated (Armour thyroid and others)
34
Q

Thyroid hormone prototype

A

Levothyroxine (Synthroid) Hypothyroidism

35
Q

Antithyroid prototype

A

Propylthiouracil Hyperthyroidism

36
Q

Iodine Prototype

A

Strong Iodine products

37
Q

What does the thyroid gland use iodine for?

A

To produce the thyroid hormones

38
Q

Antihypocalcemic prototype

A

Calcitriol Hypocalcemia

39
Q

Bisphosphonates prototype

A

Alendronate (Fosamax) (osteoporosis)

40
Q

Calcitonins Prototype

A

Calcitonin Salmon (paget disease, postmenopausal, osteoporosis)

41
Q

The hormones PTH and calcitonin work together to maintain the delicate balance of serum calcium levels in the body and to keep serum calcium levels within the normal range.

A

True

42
Q

Antidiabetic safe for children

A

Metformin

43
Q

Endocrine gland

A

produces hormones in the islets of langerhans

44
Q 
Hyperglycemia
glycosuria
polyphagia
polydipsia
lipolysis
ketosis
acidosis
A 
increased blood sugar
sugar is spilled into urine
increased hunger
increased thirst
fat breakdown
ketones cannot be removed  effectively 
liver cannot remove all of the waste products

Pharm exam 4 (1 decks)

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