Exam 4

Question 1

Inflammatory response

Answer 1

protects the body from injury and pathogens

Question 2

Hageman Factor

Answer 2

factor 12

tissue injury

Question 3

Kinin System

Answer 3

Initiate

Question 4

Bradykinin

Answer 4

Arachidonic- stimulates prostaglandins (stimulate or block inflammation response)
Leukotrienes- vasodilation (healing element) Throbaxanes- extremely potent vasoconstrictor

Question 5

Corticosteriods

Answer 5

Prednisone

Question 6

Salicylates

Answer 6

Aspirin (Bayer)  (fever blocking), (pain blocking)
Excedrin Migraine  (Ringing in ears)

Question 7

Salicylates Prototype

Answer 7

Aspirin- Anti inflammatory, anti pain (mild to moderate), anti pyretic, anti platelet

Question 8

A person who does not respond to one salicylate may respond to a different one? True or False

Answer 8

True

Question 9

Propionic Acids

Answer 9

Ibuprofen most common OTC

Question 10

Oxicam Derivative

Answer 10

Meloxicam (Mobic) chronic inflammation 1Tab

Question 11

Cyclooxygenase-2 inhibitors

Answer 11

Celecoxib (Celebrex) Cox 2 Rheumatoid arthritis helps them function

Question 12

Acetic Acids

Answer 12

Ketoralac (Toradol) Pain IV, PO, only use 3 days cause bleeding

Question 13

NSAIDS

Answer 13

Provide strong anti-inflammatory and analgesic effects
COX 1,2
Ibuprofen (Motrin), Naproxen (Aleve)

Question 14

NSAIDS drug-drug interaction

Answer 14

Loop diuretics, Beta blockers, Lithium toxicity

Question 15

NSAIDS prototype

Answer 15

Ibuprofen (Motrin)

Question 16

Cyclooxygenase 1 (COX 1)

Answer 16

found in many tissues all over the body

converts arachidonic acid to inflammatory prostaglandins

Question 17

Cyclooxygenase 2 (COX 2)

Answer 17

at the site of inflammation
highly caution
celebrex PO only

Question 18

Acetaminophen

Answer 18

most commonly taken

used to treat pain/fever

Question 19

Acetaminophen antidote

Answer 19

Acetylsysteine for ppl who over dose inhale or Iv smell like rotten eggs

Question 20

When are NSAIDs contraindicated?

Answer 20

Allergy to sulfonamides

Question 21

DMARDs

Answer 21

Disease modifying anti-rheumatic drugs

Question 22

Why DMARDs early in the diagnosis

Answer 22

before damage to the joints has occurred

Question 23

DMARD drug

Answer 23

Etanercept (Enbrel)

Question 24

Adrenal Glands location

Answer 24

flattened bodies which sit on top of each kidney

Question 25

Adrenal medulla

Answer 25

an inner core part of the SNS

Question 26

Adrenal cortex

Answer 26

an outer shell, produces hormones called corticosteroids

Question 27

Types of corticosteroids

Answer 27

Androgens (male & female sex hormones) Glucocorticoids (stimulate an increase in glucose levels for energy) Mineralocrticoids (affect electrolyte levels and homeostasis)

Question 28

Glucocorticoids prototype

Answer 28

Prednisone (replacement therapy)

Question 29

Mineralocorticoids prototype

Answer 29

Fludrocortisone (partial replacement therapy)

Question 30

Mineralocorticoids are used to block inflammation and the immune response. What is another example of their use?

Answer 30

Stimulate fat deposition

Question 31

The glucocorticoids are used systemically in endocrine disorders. There are multiple contraindications and cautions associated with their use. True or false?

Answer 31

True

Question 32

Thyroid Gland

Answer 32

Produce two thyroid hormones using iodine found in the diet Tetraiodothyronine or Levothyroxine T4 Triiodothyronine or Liothyronine T3

Question 33

Hypothyroidism

Answer 33

``` Levothyroxine (Synthroid) Thyroid Desiccated (Armour thyroid and others) ```

Question 34

Thyroid hormone prototype

Answer 34

Levothyroxine (Synthroid) Hypothyroidism

Question 35

Antithyroid prototype

Answer 35

Propylthiouracil Hyperthyroidism

Question 36

Iodine Prototype

Answer 36

Strong Iodine products

Question 37

What does the thyroid gland use iodine for?

Answer 37

To produce the thyroid hormones

Question 38

Antihypocalcemic prototype

Answer 38

Calcitriol Hypocalcemia

Question 39

Bisphosphonates prototype

Answer 39

Alendronate (Fosamax) (osteoporosis)

Question 40

Calcitonins Prototype

Answer 40

Calcitonin Salmon (paget disease, postmenopausal, osteoporosis)

Question 41

The hormones PTH and calcitonin work together to maintain the delicate balance of serum calcium levels in the body and to keep serum calcium levels within the normal range.

Answer 41

True

Question 42

Antidiabetic safe for children

Answer 42

Metformin

Question 43

Endocrine gland

Answer 43

produces hormones in the islets of langerhans

Question 44

``` Hyperglycemia glycosuria polyphagia polydipsia lipolysis ketosis acidosis ```

Answer 44

``` increased blood sugar sugar is spilled into urine increased hunger increased thirst fat breakdown ketones cannot be removed effectively liver cannot remove all of the waste products ```