Exam 4 Flashcards
Define premenopausal
The time period of endocrine changes BEFORE cessation of menstruation
Define perimenopausal
The Period of endocrine changes SURROUNDING the menopause
Define postmenopausal
The time period of endocrine changes AFTER cessation of menstruation
What are the three types of treatment for menopausal symptoms?
Nonpharmacologic therapy, menopausal hormone therapy, non-hormonal alternatives
What are the three indications for menopausal hormone therapy?
Vasomotor symptoms, vulvovaginal atrophy, osteoporosis prevention
Absolute contraindications to MHT
unexplained vaginal bleeding, pregnancy, estrogen-dependent cancer, stroke, active or history of thromboembolic disorders, active liver disease
Relative contraindications to MHT
uterine leiomyoma, migraine with aura, seizure disorder, diabetes, hypertriglyceridemia, active gallbladder disease, high risk for heart disease, family history of breast cancer
In MHT, estrogen monotherapy is only for
women without an uterus
Women with an intact uterus should be prescribed a progestin in addition to estrogen in order to
decrease the risk of endometrial hyperplasia and endometrial cancer
Initiation of MHT treatment should be limited to women…
age < 60 or within 10 years of last period
Three methods of combined estrogen and progestin administration
continuous cyclic therapy, continuous long cycle, continuous combined
Design an individualized treatment plan using pharmacologic options for menopausal symptoms
Evaluate a treatment plan on the basis of a patient’s response to pharmacologic management of menopausal symptoms
Describe the circumstances under which non-hormonal therapies for menopausal symptoms should be considered