exam 4 Flashcards

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1
Q

Amphibian b-catenin activity becomes stabilized at a site opposite that of sperm entry..

A
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2
Q

Formation of the amphibian Organizer involves high level expression of

A

high nodal: high Xnr on dorsal ( high translation of Vgt1 and VegT)

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3
Q

Which of the following are present in the Organizer?

A

Chordin, Noggin, Follistan, Xnr3

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4
Q

The left side of the Xenopus embryo is determined by

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5
Q

Which of the following can inhibit or block Wnt expression?

A

Cerberus, Dickkopf, Frzb, IGF, Tiki, Notum, Xwnt8

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6
Q

During Mid Blastula transition in Xenopus

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7
Q

The area where gray crescent forms will determine…

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8
Q

The Nieuwkoop Center is

A
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9
Q

Beta-catenin in the dorsal portion of the amphibian egg is stabilized after

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10
Q

Which of the following describes organizer Functions in Xenopus

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11
Q

Sox2 is expressed in the neural plates. Which of the following phenotypes would you expect to
observe after BMP inactivation in Xenopus embryos

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12
Q

Which of the following molecules plays a role in controlling Wnt signaling?

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13
Q

Under the influence of high levels of BMP ectoderm

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14
Q

Low levels of BMP can induce

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15
Q

Which of the following can inhibit BMP?

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16
Q

During the formation of the head and brain in Xenopus

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17
Q

The “Organizer” functions to

A
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18
Q

In the diagram at right which adhesion protein is expressed in the area labeled

A
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19
Q

During dorsal-ventral specification of the neural tube of vertebrates the protein that regulates
the formation and position of the floor plate is

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20
Q

Which of the following belongs to the TGF-b gene family?

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21
Q

Which region of the neural tube contains the least amount of sonic hedgehog?

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22
Q

Frog egg microtubule are reorganized to form the Gray Crescent during the

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23
Q

The amphibian Organizer is in the

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24
Q

The Pitx2 molecule

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25
Q

The experiment of Hemmati Brivanlou in which he tested the role of Follistatin on Activin lead to
the discovery that

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26
Q

The vegetal pole in Xenopus is a source of

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27
Q

Which of the following molecules have a conserved role in defining anterior posterior axis?

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27
Q

Which of the following phenotypes would you expect to observe inducing Noggin expression in
a ventralized embryo

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28
Q

Which of the following sentences about Xenopus Nodal Related (Xnr-1) are correct

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29
Q

Ventral tube formation can be experimentally induced

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30
Q

Which of the following factors can affect neural tube closure

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31
Q

Genetic abnormality involving motile cilia

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32
Q

During the process of garstrulation Hox genes are

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32
Q

What molecule density does the diagram on the right illustrate? Choose it from the list

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33
Q

Which of the following sentences is correct

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33
Q

Ectopic expression of Pitx2 in the developing Xenopus can

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34
Q

Spina bifida

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35
Q

During the process of dorsal ventral specification of the neural tube

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36
Q

Ectopic notochord can induce

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37
Q

Homeotic selector genes …

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37
Q

The pattern of expression of the genes that define the distinct populations of the neural tube are defined by

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38
Q

Epiboly of the ectoderm in Xenopus is a process

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39
Q

The Niewkoop center

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40
Q

Transplant of the dorsal blastopore lip (early gastrula) to another gastrula ….

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41
Q

Dorsal ventral axis in drosophila….

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41
Q

Frzb

A
42
Q

BMP gradients define dorsal-ventral axis of developing Xenopus embryo

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43
Q

Transplants of blastomers from the dorsal portion of the vegetal pole to the ventral vegetal pole
of another embryo leads to

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44
Q

Noggin plays an important role in defining the

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45
Q

During the definition of the anterior posterior axis in amphibians what defines the head

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45
Q

Second neurulation

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46
Q

Folic acid is important

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47
Q

What is the doral lip and what produces the gastrulation

A

Organizer