Exam 4 Flashcards
Most of the available antimicrobial agents are effective against:
bacteria
More than half of our antibiotics are produced by:
bacteria
True or false
Penicillin G was isolated from bacterium of the genus Streptomyces.
False
In what way semisynthetic and natural penicillins are alike?
Both have β-lactam ring in its structure
What is false about drug resistance
its found only in gram -
Which of the following antimicrobial agents is recommended for use against fungal infections?
nystatin
What does NOT affect eukaryotic cells?
semisynthetic penicillins
What is phage therapy?
The use of viruses to kill bacteria
What is NOT true about septicemia
It is caused by bacteria being present in the blood or lymph
Which of the following are Gram-positive bacteria?
1. Bacillus
2. Staphylococcus
3. Streptococcus
All
Which of the following is NOT caused by a bacterium?
1. malaria
2. plague
3. tickborne typhus
4. scarlet fever
malaria
Human-to-human transmission of Plague is usually by:
the respiratory route
A characteristic symptom of Bubonic plague is:
swollen lymph nodes
What is considered a zoonosis?
Syphilis
Most dangerous form of anthrax infection:
pulmonary anthrax
Infection with Streptococcus pyogenes can cause all of the following EXCEPT:
buboes
What about mycoplasmal pneumonia is FALSE?
treatment with Penicillin G
Tuberculosis is caused by
Gram-positive bacteria
Which one of the following is NOT a typical symptom of influenza?
diarrhea
The most effective means of preventing influenza is:
annual vaccination
The patient is suffocating because of the accumulation of dead tissue and fibrin in her throat. What is the etiology of the symptoms?
Corynebacterium
A patient has a severe cough due to mucus accumulation and is suspected to have pertussis. What is the etiology of the symptoms?
Bordetella
Which of the following is NOT an intracellular parasite?
1. Chlamydia
2. Neisseria
3. Influenza virus
4. Rickettsia
Neisseria
Mycoplasma infection causes:
Walking pneumonia
True or false
A positive tuberculosis skin test indicates that the patient has active tuberculosis.
False
True or false
Treponema pallidum is a causative agent of Syphilis.
True
Which one of the following is NOT a sexually transmitted pathogen?
1. Neisseria gonorrhoeae
2. Treponema pallidum
3.Chlamydia trachomatis
4. Varicella-Zoster
Varicella-Zoster
What organisms would MOST likely be sensitive to natural penicillin?
Streptococcus pyogenes
Which of the following pairs is NOT correctly matched for Gram reaction?
Neisseria gonorrhoeae – Gram-positive
Which statement is correct concerning penicillin?
1. it inhibits protein synthesis
2.it functions as an enzyme to cleave cell wall peptidoglycan
3. it acts on the cytoplasmic membrane
4.it prevents formation of lipopolysaccharide
5.it prevents crosslinking of peptidoglycan strands
it prevents crosslinking of peptidoglycan strands
Anthrax comes from what bacteria
Bacillus anthracis
Lyme disease comes from what bacteria
Borrelia burgdorferi
Bubonic Plaque comes from what bacteria
Yersinia pestis
Rocky Mountain spotted fever comes from what bacteria
Rickettsia rickettsii
Malaria comes from
Plasmodium falciparum
True or False
Bacteria are generally 1-2 micrometer in size.
True
Which one of the following is incorrect about viruses?
1.can have either RNA or DNA genome (but never both)
2.use host cellular machinery for replication
3.not cells
4.are usually visible under a standard light microscope
are usually visible under a standard light microscope
Which of the following have a membrane enclosed nucleus?
3. archaeal cell
1. bacterial cell
2 and 3
2. yeast cell
1 and 3
yeast cell
True or False
Peptidoglycan is part of the cell wall of all living cells.
False
Which one of the following is incorrect about bacteria?
lack nucleus
peptidoglycan cell wall
binary fission
contain mitochondria
contain mitochondria
Cell wall of a Gram-negative bacterial cell consists of:
cytoplasmic membrane and thick layer of peptidoglycan
thin layer of peptidoglycan between cytoplasmic and outer membranes
cytoplasmic membrane and thin layer of peptidoglycan
cytoplasmic membrane only
thin layer of peptidoglycan between cytoplasmic and outer membranes
Which of the statements regarding enzymes is false?
Enzymes are specific
Enzymes are proteins that function as catalysts
Enzyme activity can be regulated
Enzymes increase an activation energy of reactions
enzymes increase an activation energy of reactions
True or False
During the aerobic metabolism of glucose to CO2, the process that produces the most ATP for the cell is oxidative phosphorylation.
True
True or False
During aerobic respiration of glucose, the terminal electron acceptor is oxygen.
True
True or False
In the molecule ATP, useful energy for the cell is stored in carbon-carbon bonds.
False
True or False
Most bacteria reproduce by binary fission.
True
RNA is made of:
amino acids
ribonucleotides
lipids
deoxyribonucleotides
Ribonucleotides
Which molecules are composed of a chain of amino acids?
RNA
DNA
carbohydrates
proteins
lipids
proteins
Transcription followed by translation are the steps of:
transduction
conjugation
gene expression
replication
gene expression
Ribosomes are made of:
proteins and RNA
RNA, DNA and proteins
RNA only
Nucleic acid, proteins, and lipids
RNA and proteins
Which of the following statements about viruses is FALSE?
Viruses have genes
Viruses contain a protein coat
Viruses contain DNA or RNA but never both
Viruses use their own catabolic enzymes
Viruses use their own catabolic enzymes
Phagocytic cells of the immune system are:
all of these are phagocytic cells
neutrophils
macrophages
dendritic cells
all
Which of the following makes IgG antibodies?
monocyte
neutrophil
B cell
Plasma B cell
basophil
plasma B cell
IgG antibodies:
first produced during initial infection
most abundant in blood
pentamers
present in mother’s milk
promote allergies
most abundant in blood
Lymphocytes involved in “cell-mediated” adaptive response are:
B cells
macrophages
T cells
neutrophils
T cells
Which one of the following statements about genital warts is FALSE?
it is transmitted by direct contact
it is caused by papillomaviruses
it can lead to cervical cancer in women
lesions are always precancerous
lesions are always precancerous
An example of a latent viral infection is:
genital herpes
smallpox
flu
rhinovirus infection
rabies
genital herpes
Most of the normal microbiota of the digestive system are found in the:
small intestine and large intestine
stomach
stomach and small intestine
mouth
small and large intestine
Which of the following is directly involved in the initiation of dental caries?
crevicular fluid
sucrose
lactic acid
lysozyme
lactic acid
Streptococcus mutants that cause dental caries are:
Gram +
Gram -
gram +
Periodontitis (and possible Alzheimer’s) is caused by:
Candida albicans
Porphyromonas gingivalis
Rickettsia ricketsii
Pseudomonas aeruginosa
Staphylococcus aureus
porphyromonas gingivalis
Shigella species are a common cause of gastrointestinal ________.
intoxications
infections
infections
Staphylococcus aureus is a common cause of gastrointestinal _________.
infections
intoxications
intoxications
The most common cause of traveler’s diarrhea is:
Salmonella enterica
Helicobacter pylori
Escherichia coli
Shigella species
E. coil
Salmonella typhi is a causative agent of:
Botulism
Cholera
Typhoid fever
Shigellosis
Typhoid fever
How Dysentery is different from Diarrhea?
it is a severe diarrhea
all of the above
usually due to infection of the large intestine
mucus and blood can be present in the stools
all
“Rice water” stools and dehydration are characteristic of:
bacillary dysentery
amebic dysentery
cholera
salmonellosis
cholera
Many bacterial infections of the lower digestive tract are treated with:
antitoxin
penicillin
quinacrine
water and electrolytes
thorough cooking
water and electrolytes
Intestinal flu is caused by
flu virus
rotavirus
Escherichia coli
coronavirus
rhinovirus
rotavirus
Helicobacter pylori is responsible for:
dysentery
peptic ulcer disease
pneumonia
cholera
peptic ulcer disease
Enzyme urase:
secreted by Helicobacter pylori
all is correct
important for Helicobacter pylori survival in the stomach
involved in neutralization of stomach HCl
all is correct
Disease caused by fecal-oral transmission are:
all of these are transmitted by fecal-oral route
Shigellosis
Typhoid fever
Hepatitis A
Cholera
all of these
Epidemics related to bacterial infection of the digestive system are typically caused by:
biological vectors
contaminated food and water
unpasteurized milk
exposure to contaminated soil
contaminated food and water
Which of the following causes inflammation of the liver?
Salmonella enterica
Vibrio cholerae
Escherichia coli
Shigella spp.
Hepatitis A virus
hepatitis A virus
Infection of the brain is also called:
meningitis
encephalitis
hepatitis
colitis
encephalitis
Bacterial encephalitis difficult to treat because:
-the infections move along peripheral nerves
-antibiotics damage nervous tissue
-many antibiotics cannot penetrate the blood-brain barrier
-no medications exist for treatment of these infections
-it is very difficult to determine the causative microbe
many antibiotics cannot penetrate the blood-brain barrier
All of the following can directly cause meningitis EXCEPT:
Neisseria meningitidis
Mycobacterium leprae
Streptococcus pneumoniae
Mycobacterium leprae
Arboviruses cause ________ and are transmitted by ________.
encephalitis; mosquitoes
encephalitis; dog bites
meningitis; mosquitoes
both meningitis and encephalitis; mosquitoes
meningitis; bee stings
encephalitis; mosquitoes
Which of the following statements about rabies is FALSE?
-it is caused by Lyssavirus
-results in formation of Negri bodies in infected neurons
-most infections in the U.S. are the result of bites from infected dogs
-virus infects the cells of the nervous system
-diagnosis is based on immunofluorescent techniques
most infections in the U.S. are the result of bites from infected dogs
Botulism and Tetanus is caused by a member of which genus?
Clostridium
Mycobacterium
Vibrio
Bacillus
Lactobacillus
clostridium
Tetanus and Botulism toxins are “AB toxins”. Which of the following describes the enzymatic activity of tetanus toxin and of botulism toxin?
reverse transcriptase
DNA ligase
protease
ATPase
beta-galactosidase
protease
Which of the following pairs is mismatched?
-rabies virus – destroys cells of the CNS
-botulism – stimulates transmission of nerve impulse
-poliomyelitis – multiplication of virus occurs in throat and small intestine
-tetanus – releases potent neurotoxin
-leprosy – deformation of nose and hands can occur
botulism – stimulates transmission of nerve impulse
A pathologist detects Negri bodies while examining a brain section taken at autopsy. What was the cause of death?
bacterial meningitis
poliomyelitis
Hansen’s disease
viral encephalitis
rabies
rabies
Streptococcus pyogenes infection may cause:
warts
erysipelas
scaled skin syndrome
otitis
erysipelas
Exfoliative toxin secreted by Staphylococcus aureus is responsible for:
scalded skin syndrome
impetigo
otitis externa
fever blisters
scalded skin syndrome
Tinea pedis infection results in:
warts
diaper rash
ringworm disease
rabies
ringworm disease
A 65-year-old woman has a red, raised rash on the inside of her thighs. Stained skin scrapings show large budding cells with pseudo-hyphae. The infection is caused by:
Staphylococcus aureus
Candida albicans
Varicella-Zoster virus
Herpes simplex virus
Streptococcus pyogenes
candida albicans