Exam 4 Flashcards
Sandra is 70 years old and has just been diagnosed with leukemia. She is complaining of bone and joint pain. Which type of leukemia is most likely the culprit? A. Acute lymphoblastic leukemia (ALL) B. Acute myelogenous leukemia (AML) C. Chronic myelogenous leukemia (CML) D. Chronic lymphocytic leukemia (CLL)
D. Chronic lymphocytic leukemia (CLL)
Which type of bone marrow transplant is obtained from an identical twin? A. Xenograft B. Autologous C. Allogeneic D. Syngeneic
D. Syngeneic
During treatment for anaphylaxis, which site is used for the initial injection of epinephrine? A. Antecubital vein B. Abdomen C. Upper lateral thigh D. Deltoid
C. Upper lateral thigh
After the initial treatment for anaphylaxis, which medication should be added to prevent late-phase anaphylactic reactions? A. Albuterol B. Diphenhydramine C. H2 blocker D. Corticosteroid
D. Corticosteroid
When analyzing synovial fluid, if it has 10,000 white blood cells/mcL with 80% polymorphonuclear neutrophils (PMNs), it may be indicative of which of the following conditions? A. None, this is a normal result B. Scleroderma C. Rheumatoid arthritis D. Sickle cell disease
C. Rheumatoid arthritis
Which of the following disease-modifying antirheumatic drugs is a folic acid antagonist? A. Methotrexate (Rheumatrex) B. Etanercept (Enbrel) C. Rituximab (Rituxan) D. Anakinra (Kineret)
A. Methotrexate (Rheumatrex)
Which statement about HIV postexposure prophylaxis (PEP) for health-care workers is the most accurate?
A. PEP treatment regimens contain two antiretroviral medications.
B. PEP should be started within 72 hours of exposure.
C. PEP follow-up requires renal function tests at 6 weeks after beginning PEP.
D. PEP will prevent potential hepatitis C infection, if present.
B. PEP should be started within 72 hours of exposure.
For which patient would the clinician recommend annual HIV testing?
A. One who is in a mutually monogamous relationship that engages in anal sex
B. One who is a migrant worker
C. One who is diagnosed with viral hepatitis
D. One who is pregnant with second child from another male
C. One who is diagnosed with viral hepatitis
Reuben, age 24, has HIV and just had a routine viral load test done. The results show a falling viral load. What does this indicate?
A. A favorable prognostic trend
B. Disease progression
C. The need to be more aggressive with Reuben’s medications
D. Drug resistance mutations
A. A favorable prognostic trend
A patient with atrial fibrillation is taking warfarin (Coumadin) and has an international normalized ratio (INR) of 4.0 with no active bleeding. How should the clinician manage this patient?
A. Stop the medication for 1 week, and then repeat the INR.
B. Withhold 1 or more days of anticoagulant therapy.
C. Restart therapy at a lower dose immediately.
D. Slowly increase the dose over 3 days.
B. Withhold 1 or more days of anticoagulant therapy.
The patient with severe iron deficiency anemia is eating ice chips. Which term should the clinician use to document this finding? A. Cheilosis B. Anorexia C. Hypochromasia D. Pica
D. Pica
As a rule of thumb, the estimated level of hematocrit is how many times the value of the hemoglobin? A. Two B. Three C. Four D. Five
B. Three
What is the most common cause of microcytic anemia? A. Anemia of chronic disease B. Sideroblastic anemia C. Iron-deficiency anemia D. Pernicious anemia
C. Iron-deficiency anemia
Which symptom is the cardinal subjective symptom of sickle cell crisis? A. Pain B. Nausea C. Light-headedness D. Palpitations
A. Pain
Which phrase describes rheumatoid arthritis (RA)?
A. Localized synovial joint destruction
B. Chronic exocrine dysfunction
C. Systemic inflammatory disease
D. Antibody-mediated cellular cytotoxicity response
C. Systemic inflammatory disease
Which blood test is a nonspecific method and most helpful for evaluating the severity and course of an inflammatory process? A. Erythrocyte sedimentation rate B. White blood cell count C. Polymorphonuclear cells D. C-reactive protein (CRP)
D. C-reactive protein (CRP)
Infectious mononucleosis results from an acute infection with which of the following? A. Epstein-Barr virus B. Acute HIV infection C. Guillain-Barré D. Hepatitis
A. Epstein-Barr virus
Which condition is the most common cause of generalized musculoskeletal pain in women ages 20 to 55? A. Chronic fatigue syndrome B. Anemia C. Fibromyalgia syndrome D. Sports-related injuries
C. Fibromyalgia syndrome
After returning from visiting his grandchildren in Connecticut, George, age 59, complains of a flulike illness, including fever, chills, and myalgia. He reports having discovered a rash or red spot that grew in size on his right leg. Which disease should the clinician be considering? A. Rubella B. Lyme disease C. Fibromyalgia syndrome D. Shingles
B. Lyme disease
Dryness of the eyes and mouth is typical of which condition? A. Sjögren’s syndrome B. Allergic reaction C. Hypothyroidism D. Sideroblastic anemia
A. Sjögren’s syndrome
Exposure to ultraviolet (UV)-B and UV-A rays is a triggering factor for acute exacerbations of which condition? A. Rheumatoid arthritis B. Gout C. Systemic lupus erythematosus D. Sjögren’s syndrome
C. Systemic lupus erythematosus
What is the current goal of treatment for a patient with HIV infection?
A. Viral suppression to undetectable levels
B. Compete eradication of the virus
C. Limit contact with uninfected individuals
D. Total abstinence
A. Viral suppression to undetectable levels
Which test should the clinician use to initially screen for HIV?
A. Western blot
B. Enzyme-linked immunosorbent assay
C. HIV-1/2 antigen/antibody combination immunoassay
D. Nucleic acid amplification testing
C. HIV-1/2 antigen/antibody combination immunoassay
Which lab test would the clinician order to monitor for a significant side effect from tenofovir disoproxil fumarate? A. Urine protein B. Allele genetic testing C. Sodium level D. Hemoglobin
A. Urine protein
Which drug category of antiretroviral (ARV) therapy is generally effective in crossing the blood–brain barrier and may be useful in managing HIV-associated dementia?
A. Nucleoside reverse transcriptase inhibitors
B. Protease inhibitors
C. Integrase inhibitors
D. Nonnucleoside reverse transcriptase inhibitors
D. Nonnucleoside reverse transcriptase inhibitors
Spontaneous bruising may be seen with platelet counts below what level? A. 100,000 cells/mL B. 75,000 cells/mL C. 50,000 cells/mL D. 30,000 cells/mL
D. 30,000 cells/mL
Which type of fatigue may improve with exercise after awakening? A. Functional B. Acute C. Persistent D. Anemia associated
A. Functional
Which assessment finding presents with early rheumatoid disease?
A. Pain and swelling in both small and large peripheral joints
B. Rigid joints with diminished range of motion
C. Joint swelling and immobility on rising
D. A cardiac rub with pulmonary friction rub
C. Joint swelling and immobility on rising
Which test is diagnostic of RA? A. Rheumatoid factor B. Erythrocyte sedimentation rate C. C-reactive protein D. Anti-citrulline-containing peptide titers
D. Anti-citrulline-containing peptide titers
What is the mainstay of management for infectious mononucleosis? A. Antivirals B. Symptom control C. Corticosteroids D. Isolation
B. Symptom control
Chronic fatigue syndrome (CFS) tends to occur in which individuals?
A. Active, highly functional adults
B. Depressed middle-aged adults
C. Individuals with a depressed immune system
D. Individuals who are hypochondriacs
A. Active, highly functional adults
What is the bulls-eye rash of Lyme disease called? A. Erythema infectiosum B. Viral exanthem C. Erythema migrans D. Morbilliform exanthem
C. Erythema migrans
Which condition if left untreated will progress to complaints that include multiple joint arthritis? A. Sjögren’s syndrome B. HIV/AIDS C. Guillain-Barré D. Lyme disease
D. Lyme disease
Keratoconjunctivitis sicca is a classic sign of which condition? A. Systemic lupus erythematosus B. Sjögren’s syndrome C. Fibromyalgia syndrome D. Lyme disease
B. Sjögren’s syndrome
Which person is four times more likely to develop systemic lupus erythematosus (SLE) than a Caucasian? A. One of African descent B. An Asian C. A Hispanic D. One from the Middle East
A. One of African descent
The older adult patient has an infection. The clinician should assess for which clinical manifestation? A. Fever B. Dementia C. Confusion D. Ecchymosis
C. Confusion
Which aspect should the clinician consider when trying to determine the cause of lymphadenopathy? A. Prothrombin time B. Marital status C. Patient’s age D. Blunt trauma
C. Patient’s age
The patient has a fever of 104.2°F (40.1°C). Which condition should the clinician be considering as the etiology of the fever? A. Urinary tract infection B. Infectious hepatitis C. Tuberculosis D. Pancreatitis
D. Pancreatitis
Which type of hypersensitivity reaction should the clinician suspect in a patient who has an elevated IgE level? A. 1 B. 2 C. 3 D. 4
A. 1
In which area would the clinician evaluate a tender point in a patient with suspected fibromyalgia syndrome (FMS)? A. Fifth rib B. Trapezius C. Maxillary D. Midforearm
B. Trapezius
A patient has CFS. Which strategy should the clinician consider to manage this patient? A. Bedrest B. High-impact exercise C. Thermal biofeedback D. Cognitive-behavioral therapy
D. Cognitive-behavioral therapy
Which classic rash should the clinician assess for in a patient with SLE? A. Butterfly B. Bulls-eye C. Ringworm D. “Slapped” cheeks
A. Butterfly
Which blood cell is excessively elevated in a person who has polycythemia? A. Platelets B. Neutrophils C. Red blood cells D. All types of blood cells
C. Red blood cells
Which treatment would the clinician recommend for a patient who has relative polycythemia? A. Rehydration B. Antihistamines C. Weekly phlebotomies D. Referral to hematologist
A. Rehydration
Which behavior would the clinician advise the patient with sickle cell anemia to avoid? A. Becoming overhydrated B. Taking folic acid supplements C. Becoming physically overtaxed D. Taking rest periods during the day
C. Becoming physically overtaxed
The clinician must differentiate chronic vitamin B12 deficiency anemia from folate deficiency anemia. Which action should the clinician take?
A. Obtain a complete blood count
B. Assess for peripheral neuropathy
C. Inspect for smooth surface on tongue
D. Determine the size of the red blood cell
B. Assess for peripheral neuropathy
Which finding from the bone marrow aspiration is typical in a patient with CML? A. Schistocytes B. Howell-Jolly bodies C. Hemoglobin S gene D. Philadelphia chromosome
D. Philadelphia chromosome
How long would the clinician inform the patient to rest after onset of infectious mononucleosis? A. 4 days B. 10 days C. 2 weeks D. 4 weeks
D. 4 weeks
A patient presents with symptoms of infectious mononucleosis. Which lab chemistry test should the clinician order? A. Viral load B. Hemoglobin A1c C. Western blot assay D. Heterophile antibody test
D. Heterophile antibody test
The advance practice registered nurse (APRN) is providing a community health program for the prevention of Lyme disease. Which information should be included? A. Safe sex practices B. Hiking precautions C. Smoking cessation D. Vaccination schedules
B. Hiking precautions
The effectiveness of benzodiazepines in treating anxiety disorders suggests that which of the following neurotransmitters plays a role in anxiety? A. Acetylcholine B. Gamma-aminobutyric acid (GABA) C. Dopamine D. Serotonin
B. Gamma-aminobutyric acid (GABA)
The criteria for diagnosing generalized anxiety disorder in the American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders, 5th edition (text revision) state that excessive worry or apprehension must be present more days than not for at least: A. 1 month B. 3 months C. 6 months D. 12 months
C. 6 months
A patient presents to the clinician after experiencing four episodes in the last month of sweating, palpitations, chest pain, nausea, and shaking. Each episode lasted about 10 minutes. The patient is now becoming very fearful of future events and has been reluctant to leave the house. The clinician suspects panic disorder but wants to rule out any possible medical causes. Which of the following medical conditions can mimic the symptoms of a panic attack? A. Pheochromocytoma B. Hyperthyroidism C. Cardiac arrhythmias D. All of the above
D. All of the above
Which of the following is considered first-line treatment for panic disorders?
A. Benzodiazepines
B. Selective serotonin reuptake inhibitors (SSRIs)
C. Tricyclic antidepressants
D. Cognitive behavioral therapy
D. Cognitive behavioral therapy
Which of the following symptoms is NOT part of the diagnostic criteria for post-traumatic stress disorder (PTSD)?
A. Hypersomnolence
B. Blunted feelings
C. Loss of interest in significant activities
D. Intrusive recurrent recollections of the event
A. Hypersomnolence
Which of the following neuroendocrine abnormalities is implicated in depression?
A. Decrease in adrenal size
B. Hypersecretion of cortisol
C. An exaggerated response of thyrotropin (TRH) to infusion of thyroid-releasing hormone
D. Increased inhibitory response of glucocorticoids to dexamethasone
B. Hypersecretion of cortisol
The clinician has chosen to prescribe an SSRI instead of a tricyclic antidepressant (TCA) for a patient fitting the diagnostic criteria for depression. Which of the following is NOT true concerning SSRIs in comparison to tricyclic antidepressants?
A. SSRIs are more effective than TCAs.
B. SSRIs take less time to work than TCAs.
C. SSRIs have a more favorable side-effect profile than TCAs.
D. SSRIs are not lethal in overdose.
A. SSRIs are more effective than TCAs.
After discontinuing fluoxetine, how long must a person wait before starting a monoamine oxidase inhibitor? A. 2 weeks B. 3 weeks C. 4 weeks D. 5 weeks
D. 5 weeks
It is important to educate patients with depression and their family members about reporting signs of increasing depression and suicidal thoughts. This is especially true during which time period?
A. Prior to the antidepressant reaching therapeutic levels
B. As the mood lifts in response to antidepressant treatment
C. During dosage or medication adjustments
D. After the patient reveals suicidal thoughts or plans
B. As the mood lifts in response to antidepressant treatment
A patient is experiencing extrapyramidal side effects from his antipsychotic medications. The clinician would most likely take which of the following approaches to treating these side effects?
A. Give the patient a “drug holiday” until the symptoms resolve and then restart the medication.
B. Switch the patient to a different antipsychotic.
C. Treat the patient with anticholinergics.
D. Treat the patient with anticonvulsants.
C. Treat the patient with anticholinergics.
According to Kübler-Ross, the stages of grief occur in which order?
A. Anger, denial, depression, bargaining, acceptance
B. Anger, denial, bargaining, acceptance, depression
C. Denial, anger, depression, bargaining, acceptance
D. Denial, anger, bargaining, depression, acceptance
D. Denial, anger, bargaining, depression, acceptance
The clinician is educating a patient about the effects of marijuana. The patient stated that she has been smoking for years and believes the use does not interfere with her life. What is the potential long-term sequelae of marijuana use that the clinician should educate this patient about?
A. Memory impairment
B. Sexual dysfunction
C. Dry mouth
D. There are no long-term consequences of marijuana use
A. Memory impairment
Cocaine acts as a stimulant by blocking the reuptake of which neurotransmitter? A. GABA B. Acetylcholine C. Dopamine D. Serotonin
C. Dopamine
What blood alcohol level corresponds with the signs of stupor and confusion? A. 0.05 B. 0.1 C. 0.2 D. 0.3
D. 0.3
Rapid eye movement (REM) sleep occurs how frequently during non-REM sleep? A. Every 30 to 40 minutes B. Every 60 to 80 minutes C. Every 90 to 100 minutes D. Every 180 to 200 minutes
C. Every 90 to 100 minutes
Which of the following is a laboratory finding commonly found in patients with anorexia nervosa? A. Hypophosphatemia B. Hypermagnesmia C. Leukocytosis D. Decreased TRH
A. Hypophosphatemia
Which of the following is the only drug used to treat bulimia that is approved by the U.S. Food and Drug Administration? A. Sertraline B. Fluoxetine C. Citalopram D. Imipramine
B. Fluoxetine
Which of the following would be important to monitor in a child receiving methylphenidate for treatment of attention deficit-hyperactivity disorder (ADHD)? A. Liver function B. Vision C. Growth parameters D. Renal function
C. Growth parameters
It is important for the clinician to discuss the long-term effects of sexual assault with survivors. Which of the following is the most common long-term effect of sexual assault? A. Depression B. Obsessive-compulsive disorder C. Substance abuse D. PTSD
D. PTSD
Women are at the highest risk for developing peripartum depression for up to how long after childbirth? A. 1 to 3 weeks B. 1 month C. 3 to 6 months D. 7 months to 1 year
A. 1 to 3 weeks
Which is the most prevalent psychiatric condition in the United States? A. Depression B. Anxiety C. Substance-related addictions D. Gambling addiction
B. Anxiety
What is recorded as clinical category two of the American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders, 5th edition (text revision)?
A. Clinical disorder or focus of clinical attention
B. Personality or environmental problems
C. Environmental and psychosocial stressors
D. Global assessment of functioning
C. Environmental and psychosocial stressors
Which of the following may be used to evaluate a person’s suicide risk? A. CAGE B. SANE C. SAD PERSONAS D. DIGFAST
C. SAD PERSONAS
What is the essential feature of bipolar-I? A. Hyperactivity B. Mania C. Depression D. Anxiety
B. Mania
Bipolar disorder requires differential diagnosis from all of the following except?
A. Substance abuse and medication effects
B. Medical and neurological disorders
C. Cluster B personality disorders and depression
D. Obsessive-compulsive disorder
D. Obsessive-compulsive disorder
All benzodiazepines are associated with: A. Potential anterograde amnesia B. Dopamine-related movement disorders C. Serotonin syndrome D. Xerostomia and agitation
A. Potential anterograde amnesia
Which medication is used as a first-line treatment in the management of bipolar disorder? A. Gabapentin B. Lamotrigine C. Carbamazepine D. Topiramate
C. Carbamazepine
HITS is a validated instrument used to identifying intimate partner violence. What does HITS stand for?
A. Hit, Injured, Threatened, Scared
B. Hurt, Insult, Threaten, Scream
C. Humiliated, Isolated, Tortured, Scarred
D. Harm, Injury, Terror, Shame
B. Hurt, Insult, Threaten, Scream
Emotional dysregulation is common in:
A. Children with obsessive-compulsive disorder
B. Adults with schizophrenia
C. Adults with attention deficit-hyperactivity disorder
D. Children with tic disorders
C. Adults with attention deficit-hyperactivity disorder
The stooped posture, motor slowness, and minor cognitive impairments of patients with major depressive disorders are similar to the signs of disorders of the basal ganglia, such as: A. Parkinson’s disease B. Stevens-Johnson syndrome C. Neurological disease D. Huntington’s disease
A. Parkinson’s disease
A serious physical illness in any organ category is:
A. An independent risk factor for geriatric suicide
B. Likely to occur with body dysmorphic disorder
C. Associated with mood disorders
D. Likely to produce anxiety or panic disorders
A. An independent risk factor for geriatric suicide
Suicide plans are assessed on all of the following, EXCEPT: A. Specificity B. Possibility C. Availability D. Lethality
B. Possibility
What is the median reduction in life expectancy among those with mental illness? A. 15.4 years B. 10.1 years C. 5.7 years D. 9.2 years
B. 10.1 years
Which of the following is a potential adverse reaction to clozapine (Clozaril)? A. Prolonged QT interval B. Hyperprolactinemia C. Postural hypotension D. Myocarditis
D. Myocarditis
Each of the following antidepressants does NOT have significant liver CYP P450 interaction effects? A. Paroxetine B. Fluoxetine C. Fluvoxamine D. Olanzapine
D. Olanzapine
What term describes random quick jerking movements that flow from joint to joint? A. Dystonia B. Chorea C. Myoclonus D. Compulsions
B. Chorea
Instead of reporting symptoms of body dysmorphic disorder (BDD) to the primary-care provider, patients often request which of the following?
A. Referrals to plastic surgeons, orthodontists, or dermatologists
B. Antidepressant medications
C. Nutritional counseling services
D. Unnecessary laboratory tests
A. Referrals to plastic surgeons, orthodontists, or dermatologists
What is the leading preventable cause of death and disability? A. Opioid addiction B. Obesity C. Tobacco use D. Stress
C. Tobacco use
What is a common adverse reaction for children prescribed Risperdal for autism-associated irritability? A. Gynecomastia B. Parkinsonian-like syndrome C. Bradycardia D. Rebound hypertension
B. Parkinsonian-like syndrome
What is the advantage of guanfacine (i.e., Tenex, Intuniv) over clonidine (i.e., Catapres, Kapvay) for the treatment of ADHD?
A. Tapering off is not required on discontinuation
B. Therapeutic effect is instantaneous
C. Wider range of available dosages
D. Less sedation and longer duration of action
D. Less sedation and longer duration of action
What is a differential diagnosis of autism spectrum disorder? A. Speech sound disorder B. Duchenne muscular dystrophy C. Structural brain malformations D. Hypoxic ischemic brain injury
A. Speech sound disorder
Which intervention has been shown to diminish feelings of isolation, improve coping skills, and decrease the need for hospitalization in schizophrenia?
A. Cognitive behavioral therapy
B. Peer-delivered services
C. Family-based therapy
D. Assertive community treatment (ACT) model of care
B. Peer-delivered services
What is the likely result of the over-prescription, over-supply, and over-production of opioids? A. Opioid use B. Opioid abuse C. Opioid dependence D. Opioid resistance
B. Opioid abuse