Exam 3 Solubility Coefficients

Question 1

Name the Poorly Soluble in order of smallest to largest Blood:Gas Partition Coefficient

Answer 1

Desflurane (Suprane) (Least)
Nitrous Oxide
Sevoflurane (Ultane) (Most)

Question 2

Name the intermediately Soluble in order of smallest to largest Blood:Gas Partition Coefficient

Answer 2

Isoflurane (Forane) (Least)
Enflurane (Ethrane)
Halothane (Fluothrane) (Most)

Question 3

Name all the volatile anesthetics in order of smallest to largest Blood:Gas Partition Coefficient

Answer 3

Desflurane (Suprane) (Least)
Nitrous Oxide
Sevoflurane (Ultane)
Isoflurane (Forane)
Enflurane (Ethrane)
Halothane (Fluothane) (Most)

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Question 4

Desflurane (Suprane)
Intermediate or poor solubility?
What is the Blood:Gas Partition Coefficient?
What is the Fat:Blood Partition Coefficient?

Answer 4

Poorly Soluble
Blood:Gas Partition Coefficient: 0.42
Fat:Blood Partition Coefficient: 27.2

Question 5

Nitric Oxide
Intermediate or poor solubility?
What is the Blood:Gas Partition Coefficient?

Answer 5

Poorly Soluble
Blood:Gas Partition Coefficient: 0.46
Fat:Blood Partition Coefficient: 2.3

Question 6

Sevoflurane (Ultane)
Intermediate or poor solubility?
What is the Blood:Gas Partition Coefficient?
What is the Fat:Blood Partition Coefficient?

Answer 6

Poorly Soluble
Blood:Gas Partition Coefficient: 0.69
Fat:Blood Partition Coefficient: 47.9

Question 7

Isoflurane (Forane)
Intermediate or poor solubility?
What is the Blood:Gas Partition Coefficient?
What is the Fat:Blood Partition Coefficient?

Answer 7

Intermediately Soluble
Blood:Gas Partition Coefficient: 1.46
Fat:Blood Partition Coefficient: 44.9

Question 8

Enflurane (Ethrane)
Intermediate or poor solubility?
What is the Blood:Gas Partition Coefficient?
What is the Fat:Blood Partition Coefficient?

Answer 8

Intermediately Soluble
Blood:Gas Partition Coefficient: 1.90
Fat:Blood Partition Coefficient: 36.2

Question 9

Halothane (Fluothane)
Intermediate or poor solubility?
What is the Blood:Gas Partition Coefficient?
What is the Fat:Blood Partition Coefficient?

Answer 9

Intermediately Soluble
Blood:Gas Partition Coefficient: 2.54
Fat:Blood Partition Coefficient: 51.1