Exam 3: Renal/Digestive/Reproductive Flashcards
which of the following is not a function of the kidney?
a. excretes metabolic wastes
b. regulates blood gas concentration
c. synthesizes some hormones
d. regulates acid base balance
e. regulates water balance
b. regulates blood gas concentration
if a substance is reabsorbed from the renal tubule, where is it traveling?
into the blood
which of the following does not get filtered across the glomerular capillaries?
a. vitamins
b. RBCs
c. electrolytes
d. water
e. more than one of the above
b. RBCs
Of the 3 forces (pressures) involved in filtration, which pressure most strongly opposes filtration?
a. fluid pressure in Bowman’s space
b. glomerular capillary hydrostatic pressure
c. osmotic forces due to the protein in the plasma
c. osmotic forces due to the protein in the plasma
the structure that connects the kidney to the bladder is the
a. urethra
b. renal corpuscle
c. nephron
d. ureter
d. ureter
glomerular filtration is driven by
a. active transport
b. cotransport
c. diffusion
d. bulk flow due to capillary hydrostatic pressure
d. bulk flow due to capillary hydrostatic pressure
What are the kidney’s 2 sets of arteries and 2 sets of capillaries?
Arteries: efferent arteriole and afferent arteriole
capillaries: glomerular capillaries and peritubular capillaries
fluid in the proximal convoluted tubule is __ compared to interstitial fluid
a. hypo-osmotic
b. hyper-osmotic
c. iso-osmotic
a. hypo-osmotic
without the action of ADH, what would happen?
a. increased amount of water in the urine
b. increased amount of glucose in the urine
c. increased amount of salt in the urine
d. all are correct
a. increased amount of water in the urine
these aquaporins have consistent expression (unregulated by ADH) and are found on the basolateral membrane of the collecting duct epithelial cells
APQ3 and APQ4
sodium excreted is equal to..
a. the sodium reabsorbed plus the sodium filtered
b. the sodium filtered plus the sodium secreted plus the sodium reabsorbed
c. the sodium reabsorbed minus the sodium filtered
d. the sodium filtered plus the sodium secreted minus the sodium reabsorbed
e. the sodium filtered minus the sodium reabsorbed
e. the sodium filtered minus the sodium reabsorbed
T/F: water freely crosses cell membranes
false
If you have a concentration of 500mOsm in tubular fluid and a concentration of 700mOsm in interstitial fluid which way will water flow?
a. from the interstitial fluid to the tubular fluid
b. from the tubular fluid to the interstitial fluid
c. not enough information
b. from the tubular fluid to the interstitial fluid
Fluid in the distal convoluted tubule is ________ compared to interstitial fluid.
a. hyper-osmotic
b. hypo-osmotic
c. iso-osmotic
b. hypo-osmotic
Most of the water that goes to the renal tubule…
a. continues through circulation to the efferent arteriole
b. ends up in our pee
c. gets reabsorbed back into our blood
c. gets reabsorbed back into our blood
Which limb of the loop of Henle is impermeable to water?
ascending
What ensures that sodium stays low inside cells, thereby helping to drive sodium into the tubular epithelial cells from the tubular lumen?
Na/K pump
sodium is actively transported
a. across the apical membrane of the tubular epithelium into the epithelial cell
b. from the interstitial space into the peritubular capillaries
c. across the basolateral membrane of the tubular epithelium into the interstitial fluid
d. across the apical membrane of the tubular epithelium into the tubular lumen
e. across the basolateral membrane of the tubular epithelium into the epithelial cell
c. across the basolateral membrane of the tubular epithelium into the interstitial fluid
the proximal tubule of the nephron
a. reabsorbs HCO3- but not Cl-
b. produces a filtrate with varying osmolarity depending on plasma aldosterone
c. reabsorbs about 2/3 of the filtered Na+ at high and normal GFR
d. is important in regulating urine volume (ml/min)
e. participates in the juxtaglomerular apparatus
c. reabsorbs about 2/3 of the filtered Na+ at high and normal GFR
if a substance is freely filtered and 70% of it is reabsorbed, assuming no additional secretion, what percentage of the substance is excreted into urine?
30
Because of the active transport of sodium and chloride out of the ascending limb of the loop of Henle and its impermeability to water…
a. fluid in the distal tubule is hypo-osmotic compared to plasma
b. fluid in the ascending limb in the loop of Henle is hpo-osmotic compared to the surrounding environment
c. water is able to passively reabsorbed in the medullary collecting duct
d. two of these are correct
e. all of these are correct
e. all of these are correct
T/F: in a healthy individual, glucose can be observed in the descending loop of Henle
false
glucose travels across the basolateral membrane
a. pasively down its gradient through a transporter via facilitated diffusion
b. actively through a transporter
c. contransported with sodium, up its (glucose) gradient
d. passively through a leak channel permeable to glucose
e. none of these
a. pasively down its gradient through a transporter via facilitated diffusion
t/f: if alpha adrenergic receptors are present on the afferent arteriole, then they would also likely be present on the efferent arteriole
false
t/f: water is actively transported out of the nephron only in the medullary collecting duct
false
in the process of secretion of HCl, the primary active transporting pump is on the ___ membrane of the stomach epithelial cells, unlike the renal epithelial cells
apical
what percentage of the pancreatic cells are devoted to its exocrine digestive function?
99%
which macromolecule(s) do you begin to chemically break down in the mouth?
a. carbs only
b. fats only
c. carbs and fats
d. carbs and proteins
e. proteins only
c. carbs and fats
which cells in the epithelial lining of the stomach secrete pepsin?
chief cells
T/F: heartburn is associated with stomach acid reaching some myocardial cells and creating a burning sensation
false
which of the following is not a way that GI processes are regulated?
a. distention of the wall by the volume of contents
b. chyme concentrations of specific digestive products
c. the overall protein content in the body
d. chyme osmolarity
e. chyme acidity
c. the overall protein content in the body
the purpose of the convoluted surface area of the lumen wall of the digestive tract
a. is to aid optimal digestion
b. is to assure that things don’t get stuck in the digestive tract
c. is so that things move really slowly in the digestive tract
d. is to provide a very high surface area for absorption
d. is to provide a very high surface area for absorption
parasympathetic control of digestion..
a. ensures that saliva is more sparse and produces a dry mouth
b. ensures that saliva is plentiful and rich in enzymes
c. dampens motility of smooth muscle cells in digestive tract
d. shuts down production of stomach acid
b. ensures that saliva is plentiful and rich in enzymes
In the digestive tract, endocrine secretions end up in the ___________ while exocrine secretions end up in the _____________.
blood, intestinal lumen
right after the stomach experiences an influx of food, which of the following would then occur?
a. increase in HCl production
b. closing of the cardiac sphincter
c. gastrin release
d. two are correct
e. all are correct
e. all are correct
in addition to sodium reabsorption, aldosterone promotes
a. hydrogen ion reabsorption
b. hydrogen ion secretion
c. potassium reabsorption
d. potassium secretion
d. potassium secretion
an aldosteron receptor blocker
a. would block the action of aldosterone on the distal tubule cells
b. would block the vasoconstriction effects of angiotensin II
c. works with an ACE inhibitor to raise blood pressure
d. would turn the entire RAAS system off
a. would block the action of aldosterone on the distal tubule cells
t/f: as blood pressure rises, baroreceptor firing rate rises too
true
furosemide, a loop diuretic, blocks what?
a. Na channels in the proximal tubule apical membrane
b. NKCC transporter on ascending limb of the loop of Henle
c. AQP2 channels
d. Na/K pump
b. NKCC transporter on ascending limb of the loop of Henle
t/f: promoting sodium retention or reabsorption would most likely increase blood pressure
true
which of the following would occur if a person lost the ability to synthesize vasopressin?
a. the ability to reabsorb water in the proximal tubule would be lost
b. the excretion of glucose in the urine would increase
c. the urine production would decrease dramatically and the urine osmolarity would be hypertonic compared to plasma
d. blood pressure would increase significantly
e. the urine would become hypo-osmotic
e. the urine would become hypo-osmotic
which of the following is true regarding ANP?
a. it is secreted by macula dense cells
b. it promotes Na+ reabsorption
c. it is secreted in response to increased plasma volume
d. it decreases GFR by vasoconstricting the afferent arteriole
c. it is secreted in response to increased plasma volume
You have a patient with extensive birth defects that affect the kidney anatomy. Nevertheless, she does have some kidney function. One thing you’ve noticed in her labs is extremely low renin secretion. Which of the following anatomical locations is likely to exhibit abnormal development?
the juxtaglomerular apparatus
what does the term alkalosis mean?
a. hydrogen ion content is higher than usual
b. hydrogen ion content is higher than usual and plasma pH is low
c. plasma pH is low
d. hydrogen ion content is lower than usual
e. hydrogen ion content is lower than usual and plasma pH is low
d. hydrogen ion content is lower than usual
Lactic acid was generated by the leg muscles after a bunch of hard squats and is now circulating in the blood. Which of the following is likely to occur as a compensation of this lactic acid buildup?
a. increased plasma PCO2
b. decreased renal secretion of hydrogen ion
c. decreased urinary pH
d. decreased renal absorption of bicarbonate ion
c. decreased urinary pH
the juxtaglomerular cells
a. will secrete renin in response to low blood volume in the afferent arteriole
b. receive input from the macula densa cells about the water content of the distal tubular fluid
c. act as intra-neural baroreceptors
d. two of these are correct
e. all of these are correct
d. two of these are correct
the hydrogen ions that participate in making stomach, or gastric, acid enter the stomach lumen…
a. through active transport on apical membrane of a parietal cell, on a transporter coupled with K+
b. through active transport across the basolateral membrane of a parietal cell, on a transporter coupled with K+
c. through secondary active transport on the basolateral membrane of a parietal cell, on a transporter coupled with K+
d. through a secondary active transporter on the apical membrane of a parietal cell, on a transporter coupled with Na+
e. through active transport on the apical membrane of a parietal cell, on a transporter coupled with Na+
a. through active transport on apical membrane of a parietal cell, on a transporter coupled with K+