Exam 3 Multipe Choice Flashcards
What is the configuration of the asymmetric center in each of the following compounds?
R, S, R
What is the relationship between the compounds shown below?
Enantiomer
Which are identical compounds?
a-c
Which of the following molecules will rotate the plane of polarization of plane-polarized light?
1 only
(S)-Mendelic acis has a specific rotation of -158 degrees. What would be the observed specific rotation of (R)-Mendelic acid?
+158
Which compound has different stereoisomers?
CH3CH(OH)CH2CH(Br)CH3
Which one of these is the most appropriate definition of enatiomers?
Non-superimposable molecules that are mirror images of each other
Which of these centers can never be a chirality center as described?
An uncharged sp3-o with inly 2 bonds
Which of these when present eliminates the possibility for streoisomerism in molecules?
Plane of symmetry
Which one of these is not correct about meso compounds?
The stereoisomer must rotate plane polarized light.
Which of the following best describes a racemate or racemic mixture?
50-50% mixture of enantiomers
Which of the following structures correspond to (S)-(+)-enantiomer?
Structure A
What is the benefit of prescribing a drug as a single enantiomer?
A single enantiomer spares the patient from having to metabolize the less potent enantiomer and decreases the chance of unwanted drug interactions.
In 1992 the FDA recommended the use of modern synthesis and separation techniques to produce single enantiomer drugs. Which of the following is not a technique to separate enantiomers?
Chiral chromatography
How many chrality centers are there in the structure of penicillamine shown below?
1
