Exam 3 (Lectures 7-9) Flashcards
Strengthening exercise for CF patients
Mode: Free weights, machines, body weight
Frequency: 3-5 days/wk
Intensity: not high for children; 50-60% 1 RM for adults, 3 sets of 12 reps (physician clearance required for adults)
Duration: For adults, 30 min of strength training with inspiratory muscle training
For children, 10 - 30 min depending on # of muscle groups
U.S. prevalence of CF
30,000 cases
Volume in lungs after maximum expiration
Residual Lung Volume (RLV)
Sympathetic control of the heart
Releases norepinephrine
Has a gradual effect
US prevalence of spinal cord injury
237,000 - 301,000 cases
Combining FES leg cycling and arm cycling
May cause pain if lower extremity sensation is preserved
Systemic adaptations to spinal cord injury (8)
1) cardiovascular
2) autonomic dysreflexia
3) pulmonary
4) bowel & bladder function
5) spasticity
6) thermoregulation
7) endocrine
8) osteopenia
Sympathetic neurons synapse with
The paravertebral ganglia
3rd leading cause of death in U.S.
COPD
Effects of CF on GI Tract (4)
1) Exocrine pancreatic insufficiency
2) CF related diabetes
3) Liver disease
4) Gallbladder disease
Progression of COPD (8)
- ) enlargement of bronchial mucus glands
- ) lung parenchyma
- ) less elastic recoil of lungs
- ) greater RLV & lung hyper-inflation
- ) shortened diaphragm
- ) loss of expiratory capacities
- ) dyspnea
- ) skeletal muscle dysfunction
Chronic inflammation of the bronchi
Bronchitis
20 year old spinal cord patient life expectancy
Tetraplegia: 40+ years
Paraplegia: 45+ years
< 30% FEV1 or symptoms of chronic respiratory failure
Very severe COPD
Special considerations for CF patients based on medical history and a physical exam (5)
1) Level of pulmonary disease
2) Peripheral factors (scoliosis, kyphosis, etc.)
3) Liver disease
4) CF related diabetes (hyper or hypoglycemia)
5) Hydration level
Permanent enlargement of the bronchioles and alveoli
Emphysema
Sympathetic neurons exit the spinal column at
T1 - T6
An airway obstruction causing breathing problems
Chronic Obstructive Pulmonary Disease (COPD)
Other complications of CF
Bone disease (20% of CF patients)
Sinusitis and/or nasal polyposis
Depression (2% in children, 25% in 35+ year olds)
Volume in lungs after maximum inspiration
Total Lung Capacity (TLC)
Causes of spinal cord injury
Alcohol (25%)
Pediatric (usually congenital like spina bifida or myelomeningocele)
Modern life expectancy of CF patients
30’s, 40’s, and beyond
Diagnostic value of GXT for COPD (5)
1) symptoms may present only with exertion
2) evaluate disease progression
3) evaluate hypoxemia during activity
4) determine need for O2 supplementation
5) evaluate response to treatment
Indirect lifetime cost of spinal cord injury
> $2.1 million/person
This is characterized by mucus plugging, inflammation, and an increase in smooth muscle
Lung parenchyma
CF symptoms (11)
1) salty tasting skin
2) wheezing or shortness of breath
3) persistent cough & excessive mucus
4) frequent lung infections
5) frequent sinus infections
6) nose growths
7) poor weight gain & growth
8) foul smelling, greasy stools
9) swollen belly
10) abdominal gas & discomfort
11) broadening of fingertips & toes
Absolute contraindications to SCI GXT (5)
1) autonomic dysreflexia
2) orthostatic hypotension
3) recent deep vein thrombosis
4) pulmonary embolism
5) pressure ulcers causing autonomic dysreflexia
Functional value of exercise testing in SCI
Design an exercise program
Return to work
This is used in a diffusion test
Carbon monoxide
Cost of initial hospitalization for tetraplegia
> $80,000 (60 days)
Worldwide prevalence of CF
70,000 cases
Annual number of spinal cord injuries
40 new cases per million people
Modes for SCI exercise testing
Arm-cycling (with Velcro straps)
Wheelchair ergometry (usually higher VO2 peaks than arm-cycling)
Customized equipment
Treadmill
Rollers
2 causal mechanisms of COPD
Oxidative stress
Inflammation
Shortened diaphragm = ?
Less force development
Why do we tend to avoid upper body exercise with COPD?
It may cause dyspnea
These supply blood to the spinal cord
Spinal arteries
Secondary spinal cord injury causes (6)
1) limits to blood supply
2) infarction of grey matter 4-8 hours after injury
3) necrosis (possible up to 1-2 levels above injury)
4) fibrous & scar tissue formation
5) obstruction of neural transmission
6) nervous system dysfunction (both somatic & autonomic)
Most COPD patients have both of these
Chronic bronchitis and emphysema
Components of a Pulmonary Rehabilitation program (4)
Assessment, education, exercise training, psychosocial interventions
Parasympathetic control of the heart
Predominates at rest
Releases acetylcholine
Has a rapid effect
Shortened diaphragm = ?
Less force development
Airway clearance therapies
Exercise
High frequency chest wall compressions (i.e.: the vest)
What is cystic fibrosis (CF)?
A genetic disorder
Components of pulmonary rehabilitation for CF (6)
1) exercise training
2) nutritional counseling
3) education on managing lung disease
4) energy-conserving techniques
5) breathing strategies
6) psychological counseling and/or group support
Volume in lungs after tidal expiration
Functional Residual Capacity (FRC)
Location of the alveoli
End of respiratory tract
Life expectancy of CF patients in the 1950’s
Few lived to attend elementary school
How are spinal cord injuries classified?
Complete vs incomplete
Level
Limbs affected
X-Ray of over-extended lungs and a flattened diaphragm would indicate
Positive diagnosis of COPD
Direct lifetime medical costs of complete tetraplegia
> $1.7 million/person
Role of exercise in COPD treatment
Aerobic training of the lower body
Resistance training in whole body
Ventilatory muscle training
Incomplete spinal cord injury
Some nervous signal can be conducted through the effected area
Protocol for SCI exercise testing
Start at 5-25 Watts
Increase power 5-10 Watts per stage
1-3 minutes per stage
CFTR mutation results from
A genetic mutation on chromosome 7
FES provides improvements in (8)
1) Muscular strength and endurance
2) Energy expenditure
3) Stroke volume
4) VO2 peak and peak power
5) Lower extremity bone mineral density
6) HDL
7) Self perception
8) Body composition
In 2005, there were this many deaths in COPD patients older than 25
126,000 deaths
Accommodations for exercise testing with CF
May have to modify to allow O2 tanks
CF is inherited recessively
1 CF gene is inherited from each parent
The vagus nerve is part of which system?
Parasympathetic nervous system
Comorbidities of spinal cord injury (8)
1) cardiovascular diseases (coronary & peripheral artery disease), which may lead to amputations
2) pressure soles
3) pulmonary problems
4) obesity (lower bmr)
5) type 2 diabetes
6) osteoporosis & osteopenia
7) shoulder overuse injuries
8) bony overgrowth in joints
Causes of COPD
- ) Chronic bronchitis - excessive mucus
2. ) Emphysema - loss of functional alveoli
Medications for CF
Mucolytic agents
Antibiotics for bacterial lung infections
Other tests for diagnosing CF (10)
1) Clinical examination
2) Sputum culture
3) Chest X-Ray
4) Sinus CT scan
5) Static & dynamic lung assessment (if age appropriate)
6) Blood sampling for complete cell count
7) Liver function test
8) Renal function test
9) Nutritional parameters (total protein, albumin, fat soluble vitamins, glucose)
10) Pulmonary function testing
How to modify existing protocols for COPD (4)
1) Extend stages
2) Slower progression
3) Ramping protocols
4) Smaller increments
Sputum producing cough
Bronchitis
Median age of death in CF patients
Late 30’s
Direct cost of cystic fibrosis
> $900 million/year
Maximum volume inspired following tidal expiration
Inspiratory Capacity (IC)
Chronic inflammation of the bronchi
Bronchitis
Exocrine pancreatic insufficiency results in
Malabsorption of nutrients including fats & proteins
The spinal cord is protected by
33 vertebrae
Flexibility training in SCI
Contractures
Spasticity
Initial hospitalization costs for paraplegia
> $50,000 (50 days)