Exam 3 Lecture 19 (4-11-23) Airway Anatomy Flashcards
All of the neurological control of breathing happens in the _________.
Brainstem
(11:44)
Name the 3 parts of the brainstem
What is another name for the midbrain?
Mesencephalon
Which part of the brainstem will predominantly regulate the control of respiration?
Medulla
What does PRG stand for?
Pontine Respiratory Group
PRG regulates respiration.
What are the two main parts of the medulla?
- Ventral Respiratory Group (Front)
- Dorsal Respiratory Group (Back)
(14:10)
Where are the Botzinger (BOT) and Pre-Botzinger Complex (Pre-BOT) located?
How does the Botzinger and Pre-Botzinger Complex contribute to respiration?
VRG of the medulla.
Pace the respiratory rate.
Where is the Apneustic Center located?
What does the Apneustic Center stimulate?
What is the result of overstimulation of the Apneustic center?
Lower Pons
Apneustic Center stimulates the inspiratory neurons of the DRG in the medulla.
Overstimulation of the Apneustic Center will result in a prolonged inspiration and brief expiration.
What are two factors that Dr. Schmidt mentioned will control our respiratory drive?
- Planned movement
- Feedback from sensors and blood gas-related products
(18:00)
An increase or decrease in the following blood gas products will result in an increase in respiratory drive.
______ CO2
______ H+
______ O2
______ pH
- ↑ CO2
- ↑ H+
- ↓ O2
- ↓ pH
All these factors will increase respiratory drive.
An increase or decrease in the following blood gas products will result in a decrease in respiratory drive.
______ CO2
______ H+
______ O2
______ pH
- ↓ CO2
- ↓ H+
- ↑ O2
- ↑ pH
All these factors will reduce respiratory drive.
Where are the locations of our chemoreceptor?
- Central (brainstem)
- Periphery
The central chemoreceptors in the brainstem will typically respond to ________, _________, and _______.
- Protons
- CO2
- pH
The central chemoreceptors in the brainstem will typically not respond to changes in ______.
- Oxygen
Where are peripheral chemoreceptors located?
- Carotid Body (one on each side of the neck)
- Aortic Bodies (3 or 4 spread across the aortic arch)
Where are the baroreceptors located?
- Carotid Sinus
Chemoreceptors are in the bodies
(20:40)
How do chemoreceptors work?
Blood gas changes drive chemoreceptors (CO2, O2, H+, pH) to either increase or decrease respiratory drive.
When PAO2 drops below normal (100 mmHg), carotid body nerve impulses will increase, increasing respiratory drive.
High blood flow through the carotid bodies allows them to “see” changes in the body and make adjustments fairly quickly.
What is the primary driver of the peripheral chemoreceptors?
PCO2
↑ PCO2 ,↑ Respiratory Drive
↓ PCO2, ↓ Respiratory Drive
(23:00)
↑ PCO2 will _______ MAP.
increase MAP
Short-term response
(23:30)
How do the aortic bodies relay information back to the medulla?
Vagus Nerve (X)
This will be the same route as the baroreceptors
What pathway does the carotid body take to get back into the brainstem?
Carotid body → Hering’s nerve → Glossopharyngeal Nerve (IX) → Medulla (Nucleus Tractus Solitarius)
(24:30)
The trachea extends from the base of the ________ down to the bifurcation and splitting of the left/right bronchi.
larynx
(25:00)
What is the length of a typical trachea (range)?
By tilting the head back, how much can the trachea elongate?
11 to 13 cm
+2 cm (elongation)
(25:40)
What will happen to the internal diameter of the trachea if there is elongation?
Decreased internal diameter of the trachea.
(26:00)
The width of the trachea is similar to the width of what body part, according to Dr. James Schmidt?
Index Finger