Exam 3 - Inhaled Anesthetics, NMBD Flashcards
Halothane
Blood:Gas Partition Coefficient
MAC
Vapor Pressure
B:G = 2.54
MAC = 0.75%
Vapor Pressure = 243 torr
Enflurane
Blood:Gas Partition Coefficient
MAC
Vapor Pressure
B:G = 1.90
MAC = 1.63%
Vapor Pressure = 175 torr
Isoflurane
Blood:Gas Partition Coefficient
MAC
Vapor Pressure
B:G = 1.46
MAC = 1.17%
Vapor Pressure = 238 torr
Nitrous Oxide
Blood:Gas Partition Coefficient
MAC
B:G = 0.46
MAC = 104%
Desflurane
Blood:Gas Partition Coefficient
MAC
Vapor Pressure
B:G = 0.42
MAC = 6.6%
Vapor Pressure = 669 torr
Sevoflurane
Blood:Gas Partition Coefficient
MAC
Vapor Pressure
B:G = 0.69
MAC = 1.8%
Vapor Pressure = 157 torr
1 Hz/second decreasing to 0.1 Hz q 10 seconds
Single Twitch
3 short bursts followed by 3 short bursts
Uses 50 Hz
Double Burst
4 stimuli at 2 Hz in ½ second
Train of Four
Very rapid, 50 Hz for 5 seconds – Continuous
Tetanic Stimulation
Single twitch 3 seconds after tetanic stimulation
Post-Tetanic Stimulation
Succinylcholine:
Dose
Onset
Duration
1 mg /kg IV
Onset - 30 to 60 seconds
Duration - 3 to 5 minutes
Lower Dibucaine # indicates what?
Prolonged Succinylcholine effects - No butyrylcholinesterase
High Dibucaine # indicates what?
Normal response to Succinylcholine
Dantrolene
Use
Dose
Max dose
Malignant Hyperthermia
2 mg/kg IV
Max dose 10 mg/kg IV