Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharm Remediation > Exam 3- Diabetic Meds > Flashcards

Exam 3- Diabetic Meds Flashcards

1
Q

Metformin/Glucophage

A

Biguanides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Chlorpropamide/Diabinese

A

Sulfonylurea (1st gen)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Tolbutamide/Orinase

A

Sulfonylurea (1st gen)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Glipizide/Glucotrol

A

Sulfonylurea (2nd gen)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Glyburide/Micronase, Diabeta

A

Sulfonylurea (2nd gen)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Glimepiride/Amaryl

A

Sulfonylurea (2nd gen)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Nateglinide/Starlix

A

Meglitinides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Repaglinide/Prandin

A

Meglitinides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Rosiglitazone/Avandia

A

Thiazolidinediones (Glitazones)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Pioglitazone/ACTOS

A

Thiazolidinediones (Glitazones)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Troglitazone/Rezulin

A

Thiazolidinediones (Glitazones) (LETHAL SE)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Acarbose/Precose

A

Alpha-glucosidase inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Miglitol/Glyset

A

Alpha-glucosidase inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Sitagliptin/Januvia

A

Dipeptidyl peptidase-4 (DPP-4) inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Pramlinitide/Smylin

A

Aylin Agonist Analog (Injectable)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Exenatide/Byetta

A

Incretin mimetics (Injectable)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

1 Dec liver production of glucose #2 increase insulin sensitivity in the periphery

A

Biguanide (Metformin/Glucophage)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Increase insulin production in the pancreas (secretagogues); bind ATP sensitive K+ channels in beta cells = inc insulin release

A

Sulfonylurea (Glipizide/Glucotrol); Meglitinides (Nateglinide/Starlix)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

dec peripheral insulin resistance in skeletal m., fat cells, and liver cells by affecting gene expression of PPAR gamma #2 dec liver production of glucose

A

Thiazolidinediones (TZDs) / Glitazones (Rosiglitazone/Avandia)

20
Q

Interferes with carbohydrate absorption at the GI Brush border

A

Alpha-glucosidase inhibitors (Acarbose/Precose)

21
Q

Diminish the inactivation of GLP-1 and GIP, which serves to increase the secretion of insulin and suppress release of glucagon.

A

Dipeptidyl peptidase-4 (DPP-4) inhibitors

22
Q

Slow gastric emptying and suppress glucagon production

A

Aylin agonist analogs (Pramlintide/Symlin)

23
Q

Enhance glucose-dependent insulin secretion and suppress increased glucagon secretion and also slow gastric emptying (mimics Glucagon-like peptide 1)

A

Incretin mimetics (Exenatide/Byetta)

24
Q

Do not give to people with sulfa allergies

A

Sulfonylureas: Chlorpropamide/Diabinese, Tolbutamide/Orinase, Glipizide/Glucotrol, Glyburide/Micronase, Diabeta, Glimepiride/Amaryl

25
Q

B12 def

A

Biguanide (Metformin/Glucophage)

26
Q

Lactic acidosis, esp in ppl with renal impairment

A

Biguanide (Metformin/Glucophage)

27
Q

weight loss

A

Biguanide (Metformin/Glucophage)

28
Q

weight gain

A

Sulfonylureas (Glipizide/Glucotrol)

29
Q

Ineffective after 5-10 years

A

Sulfonylureas (Glipizide/Glucotrol)

30
Q

Med induced hypoglycemia

A

Sulfonylureas (Glipizide/Glucotrol) and Meglitinides (Nateglinide/Starlix)

31
Q

Do not use with Sulfonylureas

A

Meglitinides (Nateglinide/Starlix)

32
Q

Rapid absorption, rapid clearance

A

Meglitinides (Nateglinide/Starlix)

33
Q

Takes 6-14 wks for full effects

A

Glitazones (TZDs) (Rosiglitazone/Avandia)

34
Q

CHF

A

Glitazones (TZDs) (Rosiglitazone/Avandia)

35
Q

Only ACTOS with insulin

A

Glitazones (TZDs) (Rosiglitazone/Avandia)

36
Q

Liver function tests

A

Glitazones (TZDs) (Rosiglitazone/Avandia)

37
Q

Inc bone fractures

A

Glitazones (TZDs) (Rosiglitazone/Avandia)

38
Q

Fatal hepatic failure (rare)

A

Alpha-Glucosidase Inhibitors (Acarbose/precose)

39
Q

If hypoglycemia, use glucose not sucrose

A

Alpha-Glucosidase Inhibitors (Acarbose/precose)

40
Q

C/I with intestinal dz

A

Alpha-Glucosidase Inhibitors (Acarbose/precose)

41
Q

Inc risk for pancreatitis

A

Dipeptidyl peptidase-4 (DPP-4) Inhibitors (Sitagliptin/Januvia)

42
Q

Ok with Metformin, TZDs, Sulfonylureas but NO INSULIN

A

Dipeptidyl peptidase-4 (DPP-4) Inhibitors (Sitagliptin/Januvia)

43
Q

First approved injectable since insulin

A

Aylin Agonist Analogs (Pramlintide/Symlin)

44
Q

Synthetic version of amylin (produced with insulin in beta cells)

A

Aylin Agonist Analogs (Pramlintide/Symlin)

45
Q

Synthetic exendin-4

A

Incretin mimetics (Exenatide/Byetta)

46
Q

Gila monster spit

A

Incretin mimetics (Exenatide/Byetta)

47
Q

Used for both Types 1 and 2 DM

A

Incretin mimetics (Exenatide/Byetta); Aylin Agonist Analogs (Pramlintide/Symlin)

Pharm Remediation (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions