Exam 3 Ch. 6 Flashcards

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0
Q

Virus

A
  1. Infectious agent w/ simple acellular organization
  2. No metabolism
  3. Reproduce only w/in living host cell
  4. Size 10-400 nm
  5. Infect animals, plants, fungi, Archea, bacteria
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1
Q

Virology

A

Study of viruses & other acellular agents

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2
Q

Viruses have no ___

A

Metabolism

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3
Q

Nucleocapsid

A

Protein coat + nucleic acid

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4
Q

___ ____ encodes for protein coat

A

Nucleic acid

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5
Q

Capsid

A
  1. Protective protein coat
  2. Aids in transfer of Nucleic Acid b/w host cells
  3. Sub unit is capsomer which self assembles
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6
Q

Spikes

A

Proteins projecting from envelope often used for attachment or release from host cell, some are enzymes

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7
Q

Enveloped virus

A

Virus w/ a membrane surrounding nucleocapsid

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8
Q

Non-enveloped/ Naked Virus

A

No envelope!

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9
Q

Virion

A

Complete virus particle

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10
Q

Bacteriophage

A

Virus that infects bacteria

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11
Q

Plus/positive strand RNA

A

RNA genome identical to mRNA

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12
Q

Minus/ negative strand RNA/ DNA

A

Genome complementary to mRNA

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13
Q

Steps of Viral Multiplication

A
  1. Adsorption
  2. Entry into host cell
  3. Synthesis
  4. Assembly
  5. Release
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14
Q

Adsorption

A

Receptors on host cell bind to molecules on surface of vision

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15
Q

Entry into host cell

A

Fusion w/ host cell membrane or by endocytosis or injection of nucleic acid

16
Q

Synthesis

A

Production of virus parts by host cell

17
Q

____ ____ usually take over host cell

A

Early proteins

18
Q

____ ____ usually responsible for capsid protein production, self assembly & release

A

Late proteins

19
Q

Assembly

A

Put together vision particles either in nucleus or cytoplasm

20
Q

Release

A

Budding or lysis of host cell

21
Q

Virulent phage

A

Immediately takes over host cell followed by release from host cell by lysis

22
Q

Temperate phage

A

Can either immediately take over & Lyse host cell or can remain in host cell w/out destroying it

23
Q

Lytic

A

Take over host cell & lyse

24
Q

Lysogenic

A

Phage DNA integrates into host cell chromosome & waits till induction occurs where phage DNA is triggered to come out by stress & then takes over host cell

25
Q

Lysogeny

A

Process of bacterial cell being infected by temperate phage & copying the phage every generation

26
Q

Archeal viruses can be either

A

Virulent or temperate

27
Q

Cytocidal effect

A

Results in cell death, lysis

28
Q

Cytopathic effects

A

Damage to host cell caused by viral replication/ synthesis/release like budding, viral inclusions, enlargement of cell, fusion of cells

29
Q

Oncogenic viruses

A

Viruses that cause cancer often by inactivating tumor-suppressor genes normally in host cell

30
Q

Plaques

A

Form when virus lyses host cells

31
Q

Viroids

A
  1. Naked circular ssRNA

2. Use host cell DNA-dependent RNA polymerase to maked RNA copies

32
Q

Virusoids

A
  1. Satellite
  2. Closed circular ssRNAs
  3. Have genes
33
Q

Prion

A

Proteinaceous infectious particle
Misfolded protein
Causes normal proteins to Misfold