EXAM 3 - Blood Disorders Pt 2

Question 1

Major functions of plasma

Answer 1

Maintenance of blood volume

suspended cellular elements: RBCs, WBCs, PLTs

o2/co2

nutrient exchange

hormone transport

waste evacuation

temperature regulation

Question 2

RBC Antigens

Answer 2

80 diff types of antigens on RBC

ABO

A antigens, B antigens or Neither =O

A and B dominant over O, but codominant with each other

Rh:
If present then Rh +
if not present then Rh-

**Positive is dominate over negative

Question 3

Antibody vs antigen

Answer 3

***Antibody in PLASMA

***Antigens (A,B,AB, O) ON CELLS

Question 4

Rh Factor

Answer 4

Rh:
If present then Rh +
if not present then Rh-

Cannot give + blood to - person. Antigen (rh factor) will develop antibodies and no work.

NEG can go to POS, but not POS to NEG

Question 5

Blood Component Therapy

Answer 5

Transfusion:
Administration of whole blood or blood components directly into blood stream

Process regulated by federal government

Stringent requirements on collection, testing, storage and distribution

American Association of Blood banks

Question 6

Transfusion Options

Answer 6

Homologous Blood:
collected from volunteer donors

Autologous Blood:
collected from intended recipient prior to planned procedures

Salvaged during surgery “cell saver”

eliminates risk of alloimmunization, immune mediated transfusion reactions and transmission of viral disease

Designated (directed) blood

Collected from donor: designated by recipient