Exam 3

Question 1

VW Classification Type IA

Answer 1

Disopyramide
Procainamide
Quinidine

Question 2

VW Classification Type IB

Answer 2

Lidocaine

Mexiletine

Question 3

VW Classification Type IC

Answer 3

Flecainide
Moricizine
Propafenone

Question 4

VW Type II

Answer 4

BB

Question 5

VW Type III

Answer 5

Amiodarone
Dofetilide
Sotalol

Question 6

VW Type IV

Answer 6

Ca channel antagonists

Question 7

Amiodarone SE

Answer 7

photosensitivity, pulmonary toxicity, polyneuropathy, GI upset, bradycardia, tosades (rare), hepatic toxicity, thyroid dysfunction

Question 8

Management for torsades

Answer 8

IA, III

Question 9

mgmt of sustained monomorphic VT

Answer 9

IC

Question 10

Sustained polymorphic VT/VF w/o long QT

Answer 10

IA, IC, III

Question 11

Conversion of AF to fluter

Answer 11

IC

Question 12

What are the Class I recommendations for AF

Answer 12

ASA, ACE-I, BB (or CCB), SL nitro, statins

Question 13

Propanalol, Nadalol, Pindolol

Answer 13

Non-selective BB

Question 14

Metoprolol

Answer 14

B1 selective. Not selective at high doses

Question 15

Labetolol, Cavedilol

Answer 15

beta/alpha

Question 16

What drug do thiazides have a potentially lethal interaction with?

Answer 16

Quinidine - prolongation of QT interval can cause VT/torsades

Question 17

What is in a Prevpac?

Answer 17

PPI + Claritoromycin + Amox

Question 18

Quadruple therapy for GERD?

Answer 18

PPI/Rantidine + Metronidazole + Tetracycline +Bismuth subsalicylate

Question 19

What are the diet suggestions for hyperlipidemia

Answer 19

<7% daily calories from saturated fats

10-25g/day soluble fiber

Question 20

What are the SE of statins?

Answer 20

Myopathies

Increased liver enzymes (esp in alcoholics) - test baseline enzymes, repeat in 12 wks.

Question 21

What are the bile acid sequesterants?

Answer 21

Cholestyramine, Colestipol, Colsevelam

Question 22

Major risk factors for hyperlipidemia?

Answer 22

Smoking, ETOH, Low HDL, Fmhx of premature CHD, and age (<65 female)

Question 23

When are bile acid sequesterants contraindicated?

Answer 23

When TG levels >400mg/dL

Question 24

What are nicotinic acids used for?

Answer 24

Increase HDL - only niacin has been proven

Question 25

SE of nicotinic acids?

Answer 25

Flushing, hyperglycemia, hyperuricemia, upper GI distress, hepatotoxicity

Question 26

Nicotinic acids contraindicated in:

Answer 26

liver disease, severe gout, PUD

Question 27

What do fibric acids target?

Answer 27

Decrease TG (20-50%) 
*Gemfibrozil & Fenofibrate

Question 28

What should you look for in omega-3 and what do they do?

Answer 28

EPA & DHA combination <500mg/day up to 1000mg. Decrease TG

Question 29

What are the H2R blockers?

Answer 29

Zantac, Pepsid, Tagamet

Question 30

What types of drugs are used in Crohn’s/UC?

Answer 30

Sulfasalazides/Mesalamine, Steroids, Immunouppressants, Biologics

Question 31

Which drug for CD/UC react with allopurinol?

Answer 31

Azathioprine

Question 32

Serious SE of azathioprine/mercaptopurine?

Answer 32

Lymphomas, pancreatitis, nephrotoxicity

Question 33

What drugs can be used for IBS-C?

Answer 33

Chloride channel activators: Amitiza, Linzee

Question 34

Drugs used for IBS-D?

Answer 34

Bentyl/Levsin (anti-cholinergics/anti-spasmodics)
Lomotil
Loperamide (Imodium)

Question 35

SE of Bentyl and Levsin

Answer 35

Dry skin, blurred vision, constipation, dysphagia, photosensitivity

Question 36

Which anti-depressant can be used for IBS-D

Answer 36

Paroxetine - avoid in patients with pain and constipation

Question 37

What are two cholinergic agnoists used to increase motility?

Answer 37

Neostigmine, Bethanechol