Exam 3 Flashcards
Natural Substance Drugs
Natural substances
Marijuana, Cocaine, Opium, Caffeine, Alcohol
Artificial Drugs
LSD (acid), MDMA (ecstasy), Amphetamines
Three main effects of psychoactive effects
◦ Stimulants, Depressants, Hallucinogens
Tolerance
◦ Continued use of a drug leads to tolerance
◦ The drug’s effect lessens as the brain adapts
◦ As a result, it will take larger doses to produce the
same effect as before
Withdrawal
-If the drug is no longer used, the user may experience
discomfort and distress
-Withdrawal effects can occur even if the person is not
addicted to the drug
Dependence
Absence of the drug may lead to feelings of physical
pain and intense cravings (physical dependence)
and/or negative emotions (psychological dependence)
Wanting vs. Liking
Addiction results in increased craving, without
increased enjoyment
◦ Liking
Hedonic pleasure from a reward
◦ Wanting
Motivation and pursuit of a reward
◦ Different neural systems for liking versus wanting
◦ Addictive drugs hyper sensitize “wanting” centers of brain, but “liking” centers habituate
◦ Leads to chronic cravings for drug but drug no longer
feels good
All psychoactive drugs work by . . .
All psychoactive drugs work by altering synaptic transmission by stimulating, inhibiting, or mimicking neurotransmitters
◦ But, expectations can also influence how the
drugs affect us
What are stimulants?
Stimulants are drugs that excite neural activity and
speed up body functions
What are common stimulants?
◦ Common stimulants: caffeine, nicotine, cocaine,
ecstasy, amphetamines, methamphetamines
Psychological effects of Stimulants
Psychological effects
◦ Elevates mood
◦ Increases alertness
Stimulants often lead to a “crash” after use
◦ fatigue, irritability, headaches, depression
Physiological effects of Stimulants
Physiological effects
◦ Increase heart rate and breathing
◦ Pupil dilation
◦ Decrease appetite and increase energy
Methamphetamines
Methamphetamines
Such as “crystal meth”
◦ Also, produces psychological euphoria
Due to dopamine release
◦ Increase neural activity and speed-up body functions
◦ With drastic side effects
Insomnia, seizures, high blood pressure, and tendency towards
violent behavior
◦ Highly addictive
Chronic use can leads to drastic weight lose, poor health, bad
teeth, premature aging
Why is crack cocaine more addictive than pure cocaine?
Cocaine
◦ Caused euphoria lasting up to 30 minutes
◦ Followed by crash into an agitated depression
Crack Cocaine
◦ Can be smoked
◦ Lead to a faster high, more intense “high” that last
longer than pure cocaine
◦ But, also leads to a worse crash and more intensive
cravings
Ecstasy
Ecstasy
◦ MDMA (methylene-dioxy-meth-amphetamine)
◦ Powerful stimulant and hallucinogenic
◦ Triggers the release of dopamine and blocks the
reuptake of serotonin
◦ Produces euphoria and feelings of social
connectedness
Famous as a “party” drug
What are Depressants?
Depressants are drugs that reduce neural activity and slow body functions
Common depressants
Common depressants
◦ Alcohol
◦ Barbituates (tranquilizers)
◦ Opiates
Opiates
Opiates are derived from opium ◦ Heroin and morphine ◦ Depresses neural activity ◦ Decreases pain and anxiety ◦ Slower breathing and heart rate ◦ Pupil’s constrict ◦ Can generate feelings of bliss and euphoria Negative effects ◦ Often leads to withdrawal ◦ Reduces levels of natural endorphins in the body ◦ Withdrawal leads to intense cravings ◦ Overdose is common
Hallucinogens
Hallucinogens
◦ Distort perceptions
◦ May generate sensory images in the absence
of actual sensory input
i.e. see, hear, or feel things that aren’t really there
Common Hallucinogens
Common hallucinogens
◦ LSD
◦ PCP
◦ Cannabis
LSD
LSD (lysergic acid diethylamide)
◦ Chemically similar to a form of serotonin
LSD mimics the action of serotonin while blocking the
action of natural serotonin
◦ Can generate intense emotional experiences that
can be either positive (euphoria) or negative
(panic and terror)
Expectations play a role
Why do plants carry drugs?
◦ Plants can’t run
◦ Plant defenses are chemical warfare
Cyanide in apples and cherries deter herbivores eating
leaves
Capsaicin in hot peppers prevents most animals from
eating them
Caffeine in coffee makes small mammals sick
Nicotine in tobacco is an insecticide
Cocaine, opiates are potent toxins
DMT
-Studies the relationship between religious
experiences and a natural psychoactive compound
-DMT (dimethyltryptamine)
active ingredient of ayahuasca, a hallucinogen used by tribes in South America
-Like other psychedelic substances, DMT acts by altering the monoamine neurotransmitters
- Studies involving controlled administration of DMT
lead subjects to feel quasi-religious feelings
-Sensations of bliss, timelessness, out of body experiences, floating towards a light, presence of other beings or spirits
Neurotheology
◦ The neuroscience of exceptional human
experiences
◦ What happen in the brain when people feel the
presence of the supernatural?
Common causes of hallucinations
◦ Mental illness (schizophrenia) ◦ Drugs ◦ Extreme duress Sleep deprivation, Starvation, Illness ◦ Ritualized behavior Chanting, self-flagellation, deep meditation ◦ Sensory deprivation Like in a sensory deprivation tank
Form Constants of Hallucinations
◦ Colors and geometric shapes ◦ Tunnels ◦ Spirals ◦ Grids ◦ Cobwebs
Near Death Experiences
◦ Experiences where people feel like they had
died or been close to dying
◦ May feel like they have returned from the grave
Common experiences of near death
◦ Similar experiences reported by many Seeing a light at the end of a tunnel Visions of a world beyond Like their relatives waiting in heaven Or, how their energy would become one with the universe Intense emotions Usually positive Out of body experiences The presence of other beings
Terror Management Theory
Terror Management Theory
◦ Humans only animal aware of own mortality
◦ Awareness of mortality theorized to arouse feelings of
terror and anxiety that need to be managed
◦ To cope with the terror of mortality salience, the Self
seeks connection with things that will exist death
◦ Attitudes change in predictable ways
Become more patriotic, more religious, more family
oriented, more supportive of the extended Self
Increased drive to believe that the individual is a part
of something that will continue after death
Effects of Mortality Salience Priming
◦ Defense of cultural worldview
Patriotism, religion, family values
Greater love and tolerance others (with some exceptions)
◦ Greater dislike of people with negative view of country
◦ Greater support of harsh tactic used against national enemies
◦ Greater dislike of abstract art
Because abstract art doesn’t have a clear “meaning”