Exam 3 Flashcards
In glycolysis, __ molecules of ATP are hydrolyzed to ADP in the energy investment phase in the energy payoff phase ____ molecules of ATP, ____ molecules of pyruvate, and ___ molecules of NADH are produced. Thus, the net ATO yield from glycolysis id ___ ATP.
2, 4, 2, 2, 2
What is the job of NADH in aerobic respiration?
NADH is the electron carrier during the catabolic redox reactions involved in aerobic respiration and NADH delivers electrons to the mitochondrial electron transport chain.
During pyruvate oxidation, what also occurs?
The formation of acetyl-CoA
Once they have been processed through the citric acid cycle, the acetyl-CoA molecules from a single glucose molecule produce:
2 ATP, 6 NADH, 2 FADH, 4 CO2
What is the correct sequence of steps as energy is extracted from glucose during cellular respiration?
Glycolysis -> acetyl CoA -> Citric acid cycle -> electron transport chain
Describe the citric acid cycle:
The process produces ATP, NADH, FADH2, and CO2 in the mitochondria.
What is the difference between oxidation and reduction?
The molecule that is reduced gains electrons while the molecule that is oxidized loses electrons.
Consider the reaction below. In this reaction, _____ is oxidized and ____ is reduced.
2 H-H + O=O -> 2 H-O-H
Hydrogen; Oxygen
Remembering that rotenone blocks aerobic respiration at Complex 1, which of the following treatments could have been effective for a case of rotenone poisoning?
- Extra NAD+
- Extra Oxygen gas
- Neither
Neither
Rotenone blocks aerobic respiration at Complex 1 of the electron transport chain (ETC). what would have happened as a result of Rotenone poisoning?
The production of ATP in the mitochondria will be reduced, but the production of ATP in the cytoplasm will be normal. Glycolysis will shut down. Excessive amounts of NADH will build up.
Which produces the most ATP when glucose is completely oxidized to carbon dioxide and water?
Oxidative phosphorylation (ETC + chemiosmosis)
The diet drug DNP allows protons to bypass ATP synthase when they cross the mitochondrial membrane. In other words, DNP uncouples respiration just like the proton channel in the mitochondria of brown adipose tissue. you would expect cells exposed to DNA to produce LESS ___ and produce MORE ____.
ATP; heat
When a glucose molecule loses a hydrogen atom as the result of an oxidation-reduction reaction, the glucose molecule becomes:
Oxidized
The following molecules are all participants in the electron transport chain. which molecule functions first in the pathway when electrons are delivered to the chain from FADH2?
- Ubiquinone
- Complex I
- cytochrome c
- Complex II
- Complex III
Complex II
During oxidative phosphorylation, the amount of ATO produced from the electrons provided by one NADH molecule is different than the amount of ATP produced from the electrons provided by one FADH2 molecule. Why?
The electrons provided by FADH2 enter the ETC at a different point than the electrons provided by NADH. Because of this, they pass through fewer of the protein complexes that actively transport H= ions across the inner mitochondrial membrane, resulting in fewer ATP being produced by ATP synthase.
What is the correct order by which electrons move through the electron transport chain in mitochondria?
NADH -> Complex I -> ubiunone -> Complex III -> cytochrone c -> Complex IV -> Oxygen