Exam 3 Flashcards

1
Q

Name the system

  • transports fluids throughout the body
  • function to transfer essential materials btw external environment and internal organs
  • carries oxygen, nutrients, and waste to and from cells
A

CIRCULATORY SYSTEM

-consist of 2 systems : Cardiovascular and lymphatic systems

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2
Q

There are 2 types of systems in the circulatory system. Name the system respectively

  • collects fluid from tissue spaces and returns it to venous circulation
  • consist of heart and blood vessels (arteries, capillaries, veins)
A
  • LYMPHATIC SYSTEM

- CARDIOVASCULAR SYSTEM

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3
Q

Describe the pathway of blood flow to and from the heart

  • How many valves (from what to what)
  • What are the 2 types of circulation (what is the flow)?
A

RIGHT ATRIUM - Right Ventricle - Pulmonary arteries - LUNGS - lung capillary beds - pulmonary veins - left atrium - left ventricle - systemic arteries - systemic capillary beds - systemic veins - RIGHT ATRIUM

**4 valves 
RA to RV (tricuspid valve) 
RV to pulmonary arteries (pulmonary valve) 
LA to LV (mitral valve) 
LV to systemic arteries (Aortic valve)
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4
Q

Name the 2 types of circulation respectively
-pumps LOW OXYGEN blood from the RV to the LUNGS (through pulmonary arteries), returns oxygen-rich blood to the left atrium of the heart via pulmonary veins

-pumps OXYGEN RICH blood from LV to all parts of the BODY through the aorta, returns blood to the right atrium of the heart through superior and inferior vena cava and cardiac veins (located on heart)

A
  • Pulmonary circulation

- Systemic circulation

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5
Q

Name the blood vessel types functions respectively

  • Arteries
  • Veins
  • capillaries

What are the exceptions?

A
  • carry OXYGEN-RICH blood under relatively HIGH PRESSURE AWAY from heart to BODY
    • exception : PULMONARY ARTERY : carry LOW-OXYGEN blood to LUNGS
  • carry blood under LOWER PRESSURE than arteries; return LOW-OXYGEN blood to heart
  • *exception: PULMONARY VEINS carry OXYGEN-RICH blood back to HEART

-connect arterial and venous circulation for nutrient, O2 and waster EXCHANGE

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6
Q

Most arteries and veins consist of 3 layers:

Which is which
-inner lining of endothelial cells (single layer) supported by delicate connective tissue; allow DIFFUSION from lumen into vessel wall

  • outer connective tissue layer
  • middle smooth muscle layer; most variable layer in thickness and amount of elastic fibers; controls arterial gasometer force (constriction and dilation of vessels)
A

TUNICA INTIMA

TUNICA ADVENTITIA

TUNICA MEDIA

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7
Q

There are 3 types of blood vessels; arteries, veins and capillaries. There blood vessels can be further divided into different types.
WHat is the name of the vessel that RECEIVE the INITIAL CARDIAC OUTPUT? How?
These same vessels can maintain a CONSTANT BP, as heart contracts and relax

A

LARGE/CONDUCTING ELASTIC arteries

  • They have many layers of elastic fibers in the TUNICA MEDIA to allow expansion and recoil during the cardiac cycle.
  • This helps maintain a constant flow of blood, minimizing changes in blood pressure as the heart contracts and relaxes

E.g Aorta, arteries that originate off ARCH of area (left subclavian, left common carotid, brachiocephalic trunk) and pulmonary trunk

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8
Q

There are 3 types of blood vessels; arteries, veins and capillaries. There blood vessels can be further divided into different types.
What is the name of the vessel that are composed primarily of the smooth muscle in the tunica media. This allows vessels to DECREASE in diameter (VASOCONSTRICT) and regulate blood flow to different parts of the body

A

MEDIUM/Distributing MUSCULAR Arteries

-E.g Most of the named arteries including FEMORAL/Thigh and BRACHIAL/arm

  • **There are 3 types of artery :
  • Large/conducting elastic artery
  • medium/distributing muscular arteries
  • small arteries and arterioles
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9
Q

There are 3 types of blood vessels; arteries, veins and capillaries. There blood vessels can be further divided into different types.

1) What has narrow lumina and THICK muscular walls?
2) What helps control the filling of capillary beds and regulate the arterial pressure in the vascular system?

A

1) Small arteries and arterioles
2) Smooth muscle walls of arterioles

E.g not named or identified during dissection, arterioles can only be observed under high magnification

  • **There are 3 types of artery :
  • Large/conducting elastic artery
  • medium/distributing muscular arteries
  • small arteries and arterioles
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10
Q

There are 3 types of blood vessels; arteries, veins and capillaries. There blood vessels can be further divided into different types.

  • What are the smallest unnamed veins that drain capillaries.
  • These join to form SMALL VEINS that empty into larger veins and unite to form what?
A
  • VENULES
  • VENOUS PLEXUS

E.g venules are not named or identified during dissection and can only be observed under MAGNIFICATION. The Dorsal VENOUS ARCH of the foot is an example of a larger venous plexus

  • *There are 3 types of veins
  • Venues
  • Medium veins
  • Large veins
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11
Q

There are 3 types of blood vessels; arteries, veins and capillaries. There blood vessels can be further divided into different types.

Name the vein type

  • drain venous plexus and accompany medium arteries
  • contain small amounts of smooth muscle
  • thickest layer is TUNICA ADVERTITIA

What does this vein have special and function?

A

MEDIUM VEINS

**have VENOUS VALVES - passive flaps that permit blood to flow toward the heart but not in reverse direction (The valves help flow against gravity)

E.g named superficial veins of upper and lower limbs (cephalon and basilica of upper limb and great and small saphenous of lower limb)

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12
Q

There are 3 types of blood vessels; arteries, veins and capillaries. There blood vessels can be further divided into different types.

Name the structure and function of LARGE VEINS

A
  • contain smooth muscle
  • A well developed tunica adventitia

E.g superior vena cava, inferior vena cava, portal vein

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13
Q

Distinguishing features of veins from arteries

1) Which have thin walls? Thick wall?
2) Which have large luminal diameter?
3) Which pulsate? Spurt when severed?
4) Which accompany the other?
5) Which have valves? Why?
6) Which can expand? How?

A

1) Veins have thin walls (especially tunica media)
2) Veins have large luminal diameter
3) Veins do not pulsate or spurt blood when severed
4) Veins tend to occur as multiple vessels that ACCOMPANY v=arteries of the same name The accompany veins (L.venae Comitantes) occur as multiple vessels adjacent to an artery in a common vascular sheath
5) veins have VALVES to prevent backflow of blood
6) Veins contain approximately 80% of blood volume due to their large diameter and ability to EXPAND (arteries don’t have same capacity for expansion)

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14
Q

What are the main differences between arteries and veins

A

ARTERIES

  • Transport blood AWAY from heart
  • carry OXYGEN rICH blood (except pulmonary artery - carry low oxygen blood to lungs)
  • Have relatively NARROW LUMEN
  • Have MORE MUSCLE and elastic tissue (helps hold their shape)
  • Transport blood under HIGH PRESSURE
  • DO NOT HAVE VALVES (except valves of pulmonary artery and aorta

VEINS

  • Transport blood TOWARD the heart
  • Carry LOW OXYGEN blood (except for pulmonary veins -carry HIGH OXYGEN BLOOD to heart)
  • Have relatively LARGE LUMEN
  • Have relatively LESS MUSCLE and elastic tissue
  • Transport blood underLOWER pressure
  • HAVE VALVES throughout main veins of the body to prevent backflow of blood to body
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15
Q

What happens at capillary beds?

A

EXCHANGE OF MATERIALS

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16
Q

What micro diameter vessel allow exchange of oxygen and nutrients in tissue spaces.

A

CAPILLARIES

**They are the smallest vascular channel averaging 50micrometers in length and
8-10 micro meters in diameter(RBC are 7.5micro meter in diameter)
**They are composed of simple endothelial cell tubes

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17
Q
  • What are networks of capillaries that connect arterioles and venules called?
  • What happens at the arteriole and venule end respectively?
A
  • CAPILLARY BEDS
  • At Arteriole end ; hydrostatic PRESSURE forces fluid containing OXYGEN and nutrients out of the blood into the cellular space for exchange
  • At VENULE END ; osmotic pressure allows waste and CO2 to be reabsorbed into blood for return to the heart
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18
Q

What are the 3 vessels that do microcirculation?

A

ARTERIOLES
CAPILLARIES
VENULES

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19
Q
  • What are principal vessels?

- Name the 3 main arteries that branch from arch of aorta (carry OXYGEN-RICH blood from LV to rest of body)

A

-Principal vessels are the MAJOR named vessels of the body
-1) BRACHIOCEPHALIC TRUNK divided into ; a) right subclavian artery (feeds upper limb) and b) right common carotid artery (to head and neck)
2) LEFT COMMON CAROTID ARTERY - supplies head and neck
3) LEFT SUBCLAVIAN ARTERY - supplies upper limb
-

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20
Q

-What are the other principal vessels going to and from the heart and what do they supply

A

1) superior and fervor vena cave - return low-oxygen blood to right atrium of heart
2) Pulmonary veins - carry oxygen rich blood into left atrium of heart
3) Pulmonary trunk - carry low-oxygen blood from the right ventricle to the lungs
4) Aorta - carries oxygen-rich blood from left ventricle to tissues throughout body
5) abdomina aorta - continuation of aorta into abdomen ; gives branches to abdomina organs, divides into common iliac arteries
6) . Common iliac arteries - divide into external and internal iliac (supplies blood to pelvis and lower limb)

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21
Q

WHat is the name of the venous system that Lin’s 2 capillary beds before returning to the heart

A

PORTAL VENOUS SYSTEM

*In certain regions, blood passes through two capillary beds before returning to the heart

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22
Q

There are 2 classes of portal venous systems

Name this

  • This system drains blood from capillary beds of the digestive tract into the hepatic portal vein, which branches into capillary beds (sinusoids) of the liver
  • This allows materials to be metabolized and DETOXIFIED before returning to the heart
A

HEPATIC PORTAL SYSTEM

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23
Q

-There are 2 classes of portal venous systems

Name this

  • This system drains blood from capillary beds at the base of the hypothalamus to a capillary plexus around the anterior pituitary gland
  • This allows Neuro secretory hormones from the hypothalamus to leave the lord and stimulate cells o the anterior pituitary gland to induce the release of pituitary hormones
A

HYPOPHYSEAL PORTAL SYSTEM

**The 2 portal venous systems are Hepatic portal and HYPOPHYSEAL portal system

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24
Q

What is a one-way drainage system for returning excess fluids and cellular debris TO THE BLOODSTREAM

What are the functions of these system

A

LYMPHATIC SYSTEM

  • transport large protein molecules that cannot pas through capillaries
  • returns up to 3L of excess fluid from cellular spaces each day
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25
Q

Name the vessel

  • network of blind/closed tubes that originate in the cellular spaces of tissue
  • occur almost everywhere blood capillaries are found except teeth, bone, bone marrow, and CNS
  • lack a basement membrane so tissue fluid, proteins, bacteria and even whole cells enter easily
A

LYMPHATIC CAPILLARIES

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26
Q

What are the following

1) Network of thin-walled, valve-containing vessels that occur throughout the body
2) clear, yellowish fluid that is transported in lymph vessels
3) Masses of lymphatic tissue that filter lymph on its way to the venous system
4) large collecting vessels that unite to form Right lymphatic duct or thoracic duct

A

1) Lymphatic vessels
2) Lymph
3) Lymph nodes
4) Lymphatic trunks

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27
Q

Lymphatic trunks are large collecting vessels that unit to form right lymphatic duct or the thoracic duct; both empty into the venous system in the neck at the junction of the internal jugular veins and the subclavian veins.

How do both drain lymph?

A

RIGHT LYMPHATIC DUCT - drains lymph from the upper right quadrant of the body
-right side of the head, neck, thorax and right upper limb

THORACIC DUCT
-drains lymph from the rest of the body
Begins at CISTERNAE CHYLI (large collecting sac that merge lymphatic trunks draining the lower half of the body)
-The thoracic duct ascends into and through the thorax and joins the venous system at the LEFT VENOUS ANGLE, the junction of the left internal jugular vein and left subclavian vein

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28
Q

Name the clinical problem

1) The most common acquired disease of the arteries that is characterized by thickening and loss of elasticity of arterial walls
2) build up of fat and cholesterol in arterial walls
3) clot formed in a blood vessel or in a chamber of the heart that DOES NOT MOVE to another part of the body (it remains in the place of origin)
4) Blood clot that detaches from place of origin and travels to the blood stream

A

1) Arteriosclerosis
2) Atherosclerosis (common form of arteriosclerosis)
3) Thrombus
4) Embolus

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29
Q

Name the clinical problem

5) obstruction of a blood vessel due to an embolus
6) Area of ischemic necrosis due to TOTAL occlusion of an artery
7) PARTIAL occlusion or narrowing of an artery associated with tissue damage
8) develops if muscle tonus/firmness of arteriole smooth muscles is above normal
9) Abnormally swollen and dilated veins usually occurring in the legs. Walls of veins lose their elasticity and damaged valves allow blood to pool in the veins rather than ascending to the heart
10) swelling of tissue due to excess amount of interstitial fluid. Lymphatic system prevents this accumulation of fluid under normal circumstance

A

5) Embolism
6) Infarct
7) Stenosis
8) Hypertension (Arteriole smooth muscle control the filling of capillary beds and regulate arterial pressure in the vascular system)
9) varicose veins
10) Edema

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30
Q

Name the clinical problem

11) Regions where blood passes directly from arterial to venous sides of circulation without passing through capillaries
12) communications between arteries that supply regions of the body. These communications can occu between multiple branches of a main artery, or btw series of smaller vessels that supply a tissue in addition to its main blood supply
13) DO NOT ANASTOMOSES with adjacent arteries. Arterial occlusion result in TISSUE NECROSIS

A

11) Arteriovenous anastomoses (AV shunts)- found in regions of skin (esp fingers) for temperature regulation. Also found in the GUT and are open except during digestion
12) Arterial anastomoses - communication provide COLLATERAL CIRCULATION that is important for maintaining blood supply to a region in the case of a blockage e.g occur around the major joints ; shoulder, elbow, wrist, knee and ankle
13) End Arteries - blockage of an end artery interrupts blood flow to the organ or organ segment it supplies (i.e retina). Functional end arteries supply regions of the brain, liver, kidneys and spleen. Vital organs supplied by end arteries usually develop TISSUE NECROSIS after arterial occlusion (e.g retinal artery blockage leads to blindness)

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31
Q

1) What is the joint between the femur and tibia called?
2) What is the sesamoid bone anterior to knee joint?
3) What is on the posterior side of knee?
4) What forms he 2 joints of the ankle?

A

1) KNEE
2) PATELLA/Knee cap
3) Popliteal region
4) -One between tibia, fibula and talus
- another between talus and other bones of foot

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32
Q

How does the orientation of upper and lower extremities change with development?

A

Beginning in 4th week

  • UE and LE develop as buds with similar structure
  • arms and legs similar in structure with differences in FUNCTION
  • Both extremities develop as PROJECTIONS from body axis
  • Arms and legs initially have same orientation, PERPENDICULAR to SPINAL COLUMN (palms touch, soles touch)

DEVELOPMENT

  • UE rotate laterally (palms forward) **THUMB IS LATERAL
  • LE rotate medically (soles of feet back and down) **BIG TOE IS MEDIAL
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33
Q

How do dermatomes of lower extremity change through development?

Name the following body parts the nerves innervate 
L1
L3,L4
L4
S1
S1,S2
A

1)Spinal nerves are initially in SEGMENTAL BANDS (UE- C3-T2; LE L1-S2) that elongates: in adult lower extremity; reflect rotation

2) 
L1 - Inguinal ligament 
L3,L4 - anterior knee (patella) 
L4 - medial side of foot, BIG TOE (HALLUX in Latin) 
S1 - lateral side of foot, LITTLE TOE 
S1,S2 - posterior side of leg and thigh
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34
Q

1) What 2 parts do the inguinal ligament attach to?
2) What makes up the bones of the pelvis
3) What makes up the innominate bone
4) Where do the 3 bones that make up innominate bone join

A

1) Anterior superior iliac spine (palpable) and Pubic tubercle
2) 2 Innominate bones, sacrum and coccyx
3) Ilium, Ischium and Pubis
4) - all 3 join at acetabulum (vinegar cup -socket for hip joint)

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35
Q

1) What 2 parts do the inguinal ligament attach to?
2) What makes up the bones of the pelvis
3) What makes up the innominate bone
4) Where do the 3 bones that make up innominate bone join

A

1) Anterior superior iliac spine (palpable) and Pubic tubercle
2) 2 Innominate bones, sacrum and coccyx
3) Ilium, Ischium and Pubis
4) - all 3 join at acetabulum (vinegar cup -socket for hip joint)

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36
Q

1) What is the large opening surrounded by ischium, pubis and what is it covered by?
2) What is the large bony prominence on posterior part of ischium; people SIT on this and can get pressure from prolonged sitting

A

1) OBTURATOR FORAMEN
- COvered by the OBTURATOR membrane for muscle attachment
2) ISCHIAL TUBEROSITY

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37
Q

1) What is the name of the Ligament that join the sacrum with the ischial spine
2) What is the name of the ligament that join the sacrum to the ischial tuberosity

3) What is the MAIN function of these 2 Ligaments

A

1) Sacrospinous ligament
2) Sacrotuberous ligament

3) Sacrospinous and Sacrtuberous ligaments PREVENT SACRUM from ROTATING due to weight transmitted down the vertebral column

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38
Q

NAme the part of the femur

1) Which part of femur is subject to FRACTURE?
2) What is the INDENTATION on the head called ? (For ligament of head to femur)
3) What is located LATERALLY below the neck
4) What is located MEDIALLY below the neck?
5) What is the ridge that connects the 2 trochanter on ANTERIOR side?
6) What is the ridge that connects the 2 trochanter on POSTERIOR side?
7) A large ridge along the length of femur on POSTERIOR side; site of insertion of mUSCLES of thigh
8) A bump located SUPERIOR to the medial epicondyle

A

1) Neck of femur (NARROW REGION)
2) Fovea capitis
3) Greater trochanter
4) Lesser trochanter
5) INTERTROCHANTERIC line
6) Intertrochanteris CREST
7) LINEA ASPERA
8) Adductor tubercle

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39
Q

Name the parts of tibia

1) bumps on anterior side of tibia - for attachment of patella tendon
2) proximal ends of tibia that articulated with femur
3) distal end of tibia
4) oblique ridge on back of tibia

Name the 3 parts of the fibula

A

1) Tibia tuberosity
2) Medial and lateral CONDYLES
3) Medial malleolus tibia
4) SOLEAL LINE

Fibula

1) Head
2) Neck
3) Lateral malleus fibula

***The lateral malleolus and the medial malleolus forms a joint in between for DORSIFLEXION, PLANTAR FLEXION

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40
Q

What connects superficial veins to deep veins; have valves that only allow flow from SUPERFICIAL TO DEEP, Not DEEP TO SUPERFICIAL

A

PERFORATING VEINS

**SUPERFICIAL Veins drain toward body or to deep veins and the VALVES in perforating veins prevent backflow

**Incompetent perforating veins lead to VARICOSE VEINS

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41
Q

ILIOPSOAS

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Ilium, Vertebra (T2-L5)
Insertion - Femur
Action - Flex the hip joint
Nerve - Femoral nerve

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42
Q
PECTINEUS
Origin
-Insertion 
-Action 
-Nerve
A

Origin - Pubis
Insertion - Femur
Action - Flex hip joint
Insertion - Femoral nerve

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43
Q

SARTORIUS

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Ilium (Anterior Superior iliac spine)
Insertion - Tibia
Action - Flex hip Joint, Flex knee
Nerve - Femoral nerve

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44
Q

RECTUS FEMORIS

  • Origin
  • Insertion
  • Action
  • Nerve

**What is special about this muscle?

A

Origin -Ilium (Anterior Inferior Iliac spine)
Insertion - Patella
Action- Flex hip joint, extend the knee
Nerve - Femoral nerve

**It is BIFUNCTIONAL - cross both HIP and KNEE Joints

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45
Q

VASTUS LATERALIS

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin -Femur
Insertion - Patella
Action - Extend the knee
Nerve - Femoral nerve

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46
Q

VASTUS MEDIALIS

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Femur
Insertion- Patella
Action - Extend knee
Nerve - Femoral nerve

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47
Q

VASTUS INTERMEDIUS

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Femur
Insertion - Patella
Action - Extend the knee
Nerve - Femoral Nerve

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48
Q

What are he quadriceps?
WHat is there insertion?
How do they insert?

A

Quads- RECTUS femoris, VASTUS lateralis, VASTUS medialis, VASTUS INTERMEDIUS

Insertion - PATELLA

  • *Quads insert to patella via QUADRICEPS tendon
  • *Patella is linked to the Tibia via Patella tendon
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49
Q

GRACILIS

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Pubis
Insertion -Tibia
Action - ADDUCT hip joint, FLEX knee
Nerve - OBTURATOR Nerve

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50
Q

ADDUCTOR LONGUS

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Pubis
Insertion - FEMUR (linea aspera)
Action- ADDUCT hip joint
Nerve - OBTURATOR

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51
Q

ADDUCTOR BREVIS

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Pubis
Insertion- Femur (linea aspera)
Action - ADDUCT hip joint
Nerve - OBTURATOR nerve

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52
Q

ADDUCTOR MAGNUS (Adductor portion)

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Pubis, Ischium
Insertion - Femur (linea aspera)
Action - ADDUCT Hip joint
Nerve - OBTURATOR nerve

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53
Q

ADDUCTOR MAGNUS (Hamstring portion)

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Ischial tuberosity
Insertion - Femur (Adductor tubercle - Superior to the medial epicondyle)
Action - Extend the hip joint
Nerve - **SCIATIC NERVE (Tibia part)

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54
Q

OBTURATOR EXTERNUS

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - OBTURATOR membrane
Insertion - Femur
Action - LATERALLY rotate femur at hip joint
Nerve - OBTURATOR nerve

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55
Q

GLUTEUS MAXIMUS

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Ilium, sacrum, coccyx, sacrotuberous ligament
Insertion - Femur, Iliotibial tract (IT band)
Action - Extend, LATERALLY rotate femur (also keeps legs extended via IT tract/band)
Nerve - Inferior gluteal nerve

**LARGEST EXTENSORS OF THIGH
Used in running, climbing stairs and raising from stooped position

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56
Q

GLUTEUS MEDIUS

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Ilium
Insertion - Femur (Greater trochanter)
Action - ABDUCT and MEDIALLY rotate femur; (support weight when lift opposite leg)
Nerve - Superior gluteal nerve

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57
Q

GLUTEUS MINIMUS

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Ilium
Insertion - Femur (Greater trochanter)
Action - Abduct and medially rotate the femur, (support weight when lift opposite leg)
Nerve - Superior gluteal nerve

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58
Q

TENSOR FASCIA LATA

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Ilium (Anterior superior iliac spine)
Insertion - Iliotibial tract (IT band)
Action - Abduct femur (also keeps leg extended via IT tract)
Nerve - Superior gluteal nerve

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59
Q

PIRIFORMIS ** (LANDMARK)

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Sacrum
Insertion - Femur (Greater trochanter)
Action - LATERALLY rotate femur
Nerve - Nerve to PIRIFORMIS

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60
Q

OBTURATOR INTERNUS

  • Origin
  • Insertion
  • Action
  • Nerve
A

ORIGIN - OBTURATOR membrane
Insertion - Femur (Greater trochanter)
Action - LATERALLY rotate femur
Nerve - Nerve to OBTURATOR internus

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61
Q

SUPERIOR GEMELLUS

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Ischial Spine
Insertion - Femur (Greater trochanter)
Action - LATERALLY rotate femur
Nerve - Nerve to OBTURATOR internus

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62
Q

INFERIOR GEMELLUS

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Ischial tuberosity
Insertion - Femur (Greater trochanter)
Action - LATERALLY rotate the femur
Nerve - Nerve to quadratics femoris

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63
Q

QUADRATUS FEMORIS

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Ischial tuberosity
Insertion - Femur
Action - LATERALLY rotate the femur
Nerve - Nerve to quadratus femoris

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64
Q

SEMIMEMBRANOSUS

  • Origin
  • Insertion
  • Action
  • Nerve
A

ORIGIN - ISCHIAL TUBEROSITY
Insertion - Tibia
Action - Flex knee, Extend Hip joint
Nerve - Tibial part of sciatic nerve

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65
Q

SEMITENDINOSUS

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Ischial tuberosity
Insertion - Tibia
Action - Flex knee, Extend Hip joint
Nerve - Tibial part of sciatic nerve

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66
Q

BICEPS FEMORIS

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Ischial tuberosity (long head), Femur (short head)
Insertion - Tibia
Action - Flex knee, extend Hip joint (LONG HEAD only)
Nerve - Long head: Tibial part of sciatic nerve.
Short head : Common perineal part of sciatic nerve

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67
Q

ADDUCTOR MAGNUS (hamstring part)

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Ischial tuberosity
Insertion - Femur
Action - Extend hip joint
Nerve - Tibial part of sciatic nerve

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68
Q

POPLITEUS

  • Origin
  • Insertion
  • Action
  • Nerve
A

ORIGIN- Femur
Insertion - Tibia
Action - Laterally rotate the femur (unlock knee)
Nerve - Tibial nerve

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69
Q

There are 3 parts of the superficial group of the POSTERIOR LEG : Gastrocnemius, soles and plantaris

GASTROCNEMIUS

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Femur
Insertion - Calcaneous
Action - Plantar flex foot (weak flex knee)
Nerve - Tibial nerve

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70
Q

There are 3 parts of the superficial group of the posterior leg: Gastrocnemius, soleus and plantaris

SOLEUS

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Fibula, Tibia (soleal line)
Insertion - Calcaneus
Action - Plantar flex foot
Nerve - Tibial nerve

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71
Q

There are 3 parts of the superficial group of the posterior leg: Gastrocnemius, soleus, and plantaris.

PLANTARIS

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Femur
Insertion - Calcaneus
Action - Plantar flex foot
Nerve - Tibial nerve

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72
Q

There are 3 parts of the Deep group of the posterior leg: Flexor hallucis longus, flexor digitorum longus, Tibialis Posterior

FLEXOR HALLUCIS LONGUS

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Fibula
Insertion - Distal phalanx of BIG TOE
Action - Plantar flex BIG toes, Plantar flex foot
Nerve - Tibial nerve

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73
Q

There are 3 parts of the Deep group of the posterior leg: Flexor hallucis longus, flexor digitorum longus, Tibialis Posterior

FLEXOR DIGITORUM LONGUS

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Tibia
Insertion - Distal phalanges of lateral FOUR TOES
Action - Plantar flex lateral FOUR TOES, plantar flex foot
Nerve - Tibial nerve

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74
Q

There are 3 parts of the Deep group of the posterior leg: Flexor hallucis longus, flexor digitorum longus, Tibialis Posterior

TIBIALIS POSTERIOR

  • Origin
  • Insertion
  • Action
  • Nerve
A

Origin - Tibia, Fibula, Interosseous Membrane
Insertion - Navicular bone, cuneiform, cuboid, metatarsals 2-4
Action - Plantar flexes foot, Inverts foot
Nerve - Tibial nerve

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75
Q

what are the 4 principles/stages of development ?

A

1) DIFFERENTIATION - single fertilized egg produce different cell types
2) MORPHOGENESIS - The different cell types are then organized into tissues
3) GROWTH - Cell division
4) MATURATION - fully formed organs continue to develop functionally (even continues after birth)

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76
Q

How does a single fertilized egg differentiate i.e produce different cell types?

HINTs
What characteristics make it possible
Same or different genome?
Activation or restriction of genes? Which genes?

A

-All have same genome
-restriction of genes that are active in different cell types
-INDUCTION
A) Paracrine factors ; signal transduction pathways - growth factors, receptors, kinase cascades
B) Positional information ; cell-cell interactions

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77
Q

A single cell can be differentiates into different cell types which the help of several factors. When these cells differentiate, how can they be organized into tissues? What is the process called?

HINT
2 WAYS OF organization into tissues

A

MORPHOGENESIS

1) Migration
2) Apoptosis

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78
Q

How do cells/tissues grow?

A

By CELL DIVISION

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79
Q

GIve a brief summary/breakdown of the timeline through out gestation

HINT
Just the weeks classification and summary of events

A

WEEKS 1-3

  • Fertilization through gastrulation
  • Primary germ layers (ectoderm, mesoderm, endoderm)

WEEKS 3-8

  • Embryonic period
  • Organogenesis ;differentiation of the 3 germ layers (cardiac, nervous, skeletal system, eye, ear, limb buds, face, GI tract, long bud, genitalia)

WEEKS 9-38

  • Fetal period
  • Maturation of tissues and organs
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80
Q

In order for cells to grow, they must divide. These cell divisions lead to distinction between inside and outside of the cell. What is this ability of cells to make this fake decision called? What are the distinctions?

When does this face decision begin?

A

EARLY FATE DECISIONS (fake decisions)

Inside cells (ICM -inner cell mass) - form EMBRYO 
Outside cells (Trophoblast) - form part of PLACENTA 

**Beings with COMPACTION of BLASTOMERES at 8 cell stage

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81
Q

What are. The 2 early. Fate decisions
What Does fate decision. Mean?
What does the fate decision ultimately lead to?

A

1) 2 early fate decisions
A) Joining adjacent cells : fertilized egg - blastocyst - differentiate to ICM (will form embryo) and trophoblast (will form part of placenta)
B) Determines whether ICM cells will form EPIBLAST (form amnion and body of embryo) or HYPOBLAST (form wall of primitive and secondary yolk sac)

2) Fate decision means that the cells become more restricted as to which cell types their progeny will become. Some genes inactivated in some cells while others remain activated

3) Fate decisions lead to formation of 3 germ layers (mesoderm, ectoderm and endoderm) by the ICM
ICM - epiblast - primitive ECTODERM - embryonic ECTODERM
ICM - epiblast - primitive ECTODERM - primitive streak -embryonic ENDODERM
ICM - epiblast - primitive ECTODERM - primitive streak - embryonic MESODERM
ICM - epiblast - primitive ECTODERM - primitive streak - extraembryonic MESDODERM
ICM - hypobast - extraembryonic ENDODERM - YOLK SAC
Trophoblast - Cytotrophoblast - Syncytiotrophoblast

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82
Q

Match the following with their appropriate primary germ layers:

1) Nervous system, skin-EPIDERMIS (hair, glands), cornea and lens
2) Muscles, bones, cartilage, skin- DERMIS, heart, blood vessels, blood cells, KIDNEY, gonads and reproductive tract
3) GI TRACT EPITHELIUM, liver, pancreas, pharynx (NECK), thyroid and parathyroid gland, respiratory tract epithelium (LUNGS), BLADDER
4) Gametes (spermatogonia and oogonia) - migrate to somatic part of gonads

A

1) ECTODERM
2) MESODERM
3) ENDODERM
4) GERM CELLS

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83
Q

WEEK 1 of early development is from fertilization to Implantation. Name the daily steps

A

Day 1 - Fertilization (zygote contain 1 set of chromosome from each parent)
Day 2 - 2 cells
Day 3 - Morula
Day 4 - Early blastocyst
Day 5 - Late blastocyst
Day 6 - BEGINNING of implantation
Day 7 - INVASION of ENDOMETRIUM (embryo is ready to implant to uterus)

*** fertilized egg - blastocyst- TROPHOBLAST and ICM

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84
Q

WHat happens in day 1 of week 1?

** What must happen for Implantation to occur of day 7?

A

FERTILIZATION

  • creates a new diploid individual (male and female pronuclei)
  • Determines SEX of individual
  • Takes place in AMPULLA of OVIDUCT (Fallopian tube)
  • Oocyte completes meiosis division
  • Sperm DNA must decondense
  • 2 pronuclei replicate DNA before first cell division

*** For Implantation to occur, blastocyst must break out of zona pellucid a

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85
Q

WHAT Is the goal of Week 2 ?

How

A

GOAL : Development of Placenta and BILAMINAR Embryo

  • Embryo fully embedded in uterine wall
  • Establishment of placental circulation
  • Formation of first germ layers
  • Formation of extraembryonic membranes and cavities

**Trophoblast - cytotrophoblast

BILAMINAR EMBRYO
ICM - HYPOBLAST (forms extraembryonic tissues) and EPIBLAST (forms all tissues of the embryo and amnion)

2 cavities

  • Epiblast - separate to 2 layers to form amniotic cavity (top layer - amnion, lower layer - embryo)
  • Cells from by HYPOBLAST line the trophoblast - form primitive yolk sac or extracoelomic cavity
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86
Q

What are the results of the Week 2 ?

A

1) 2 layer embryo
- Epiblast is primitive ECTODERM (3 germ layers)
- Hypoblast is primitive ENDODERM (yolk sac)

2) Cavities
- Amniotic membrane forms from epiblast creates amniotic cavity
- Yolk sac lined with hypoblast and spinachnic extraembryonic mesoderm

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87
Q

What are the events in Week 3

A

GASTRULATION

  • process leads to development of the 3 primitive germ layers (embryonic ectoderm, endoderm and mesoderm)
  • cell migration and differentiation converts BILAMINAR disc to TRILAMINAR disc
  • Begins with the formation of primitive groove
  • establishment of body axes (movement of cells and elongation of the embryonic disc establishes BODY AXES)
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88
Q

What happens EARLY in week 3?

A
  • the primitive streak begins to appear in the CAUDAL HALF of the BILAMINAR DISC (Anterior end is the primitive node)
  • Epiblast cells migrate LATERALLY and ANTERIORLY through the primitive streak
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89
Q

WHat is the precursor to the creation of the 3 germ layers in week 3?

A

-Invagination of EPIBALST into the streak (primitive ectoderm) creates the 3 germ layers (ectoderm, mesoderm, endoderm)

  • some replace the hypoblast to form embryonic ENDODERM
  • others moving between the epiblast and hypoblast create the embryonic MESODERM
  • remaining epiblast cells form the ECTODERM
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90
Q

In week 3, how is Notochord formed and what does it differentiate into?

A

Epiblast - Mesoderm - Notochord - SPINE

  • The ANTERIOR end of the primitive streak is the primitive node (HENSON’s NODE)
  • Mesodermal cells anterior to the node form a solid cord in the midline called the NOTOCHORD
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91
Q

In week 3, the Notochord is formed from the mesodermal cells of the epiblast,
* name 3 roles of the notochord?

A
  • signals from the NOTOCHORD induce the overlying ECTODERM to become NERVOUS😬 TISSUE
  • signals some of the MESODERMAL cells to become vertebral bodies of the SPINE (nucleus PULPOSUS)
  • Forms nucleus PULPOSUS of the vertebral disc

**egg - blastocyst - ICM - Epibast - mesoderm - Notochord - Spine (nucleus PULPOSUS of vertebral disc)

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92
Q

In Week 3, what happens with time to the notochord and primitive streak?

WHat happens to the primitive streak remnant? What is this called?

A

-With time, the notochord extends anteriorly (gets longer) while the primitive STREAK gets SHORTER

  • The remnant of the primitive streak is called SACROCOCCYGEAL TERATOMA
  • *These are generally bending tumors containing tissues derived from all 3 germ layers
  • *Mostly found in FEMALES
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93
Q

Name the following from week 3 of development

1) SITE of future ORAL CAVITY (contain only ECTODERM and ENDODERM)
2) Contributes to structures in the forebrain and oral cavity (only MESODERM)
3) SITE of FUTURE ANUS (only ECTODERM and ENDODERM

A

1) Oropharyngeal membrane
2) Prechordal plate (prechordal mesoderm)
3) Cloacal membrane

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94
Q

What happens in weeks 3-8?

A

-ORGANOGENESIS (differentiation of the 3 germ layers - ectoderm, mesoderm and endoderm)

ECTODERM - nervous system, neural crease walls, skin
MESODERM - paraxial, intermediate, lateral plate, extraembryonic mesoderm)
ENDODERM - epithelial lining of GI tract, lungs, urethra, bladder, parenchyma of thyroid and parathyroid hormone, liver, pancreas, stroma of tonsils and thymus, parts of ear

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95
Q

Between weeks 3-8, the 3 germ layers which were originally formed in week 1-3 get differentiated in a process called ORGANOGENESIS.

What are the derivatives of ECTODERM?
What problems can result?

A

1) Neural TUBE - form central and peripheral NERVOUS SYSTEM
2) Neural crest
- cells at the crest of neural fold form neural crest cells
- variety of structures in the HEAD
- ganglia
- Adrenal medulla
- Melanocytes
3) Surface ectoderm
- form epidermis and appendages of the SKIN
- glands, hair, nails
- mammary and pituitary glands
- tooth enamel

**Neural tube defects (Anencephaly, Spinal bifid - can both be prevented by folic acid)

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96
Q

What is neurulation?

WHen does it occur? Week period and day ?

A

BASICALLY notochord signal ectoderm to form neural plate

  • Ectoderm above the notochord and prechordal plate forms the NEURAL PLATE beginning at DAY 19
  • Signals from the notochord induces the overlying ECTODERM to form the NEUROECTODERM of the NEURAL PLATE
  • neuroectoderm begins to fold into a TUBE

**Ectoderm from notochord and prechordal plate - neural plate - neuroectoderm - neural tube

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97
Q

On day 19, neurulation occurs where ectoderm above the notochord join with prechordal plate to form neural plate, neural plate further differentiate into neural ectoderm to form neural tube.

How do theses neural stuff separate out?

A

1) Neural fold closes into a tube (begins in the future CERVICAL region at somite 5- fusion proceeds CRANIALLY and CAUDALLY)
2) Cells at the boundary between neural ectoderm and surface ectoderm will become Neural CREST cells (These crest cells separate from the neural tube and migrate to from parts of the PNS)
3) Surface ectoderm - cover the neural tube and rest of embryo and form the EPIDERMIS

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98
Q

How does the neural tube close i.e what are the last regions to close?
What day is it completely closed?
What will happen if neural tube don’t close completely?
What are tx/prevention?

A

1) ANTERIOR and POSTERIOR neuropore are the LAST regions to close
2) Neural tube is completely closed by DAY 28

3) NEURAL TUBE DEFECTS
A) Anencephaly - FATAL - failure to properly close the neural tube at the CRANIAL end
B) Spinal bifida - failure to close the neural tube from the CERVICAL region to the CAUDAL end

4) FOLIC ACID can prevent neural tube defects before and during pregnancy

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99
Q

What do the cells at the crest of the fold form?

What does this differentiate into?

A

1) NEURAL CREST CELLS

2) Neural crest cells migrate to other areas to form specific structures
- Dorsal root ganglion
- Sympathetic ganglion
- Developing suprarenal gland (epinephrine, norepinephrine/ flight or fight)
- preaortic ganglion
- enteric ganglia

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100
Q

NAME the following fates of the Mesoderm

1) CRANIAL end of node and LATERAL region of primitive streak
2) Midstreak
3) More caudal, splits into 2 layers - parietal/somatic and splanchnic/visceral
4) Most CAUDAL

A

1) Paraxial mesoderm (PM)
2) Intermediate mesoderm (IM)
3) Lateral plate mesoderm (lpm)
4) Extraembryonic mesoderm (eem)

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101
Q

WHat are the 2 parts of lateral plate mesoderm and what germ layer are each close to respectively?

A

1) Parietal/somatic layer - close to ECTODERM

2) Visceral/splancnic - close to ENDODERM

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102
Q

What part of the mesoderm organize into paired SOMITES adjacent to the neural tube and notochord? And form the AXIAL SKELETON, associated muscle and DERMIS of skin?

**How do the somites increase in number? Cranial to caudal or caudal to cranial?

A

PARAXIAL MESODERM

  • Development begins at the CRANIAL end and somites increase in number CAUDALLY
  • *somites increase in number 2-3 a day

***Paraxial mesoderm - somites - axial skeleton/muscle/dermis

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103
Q

In week 1-3 fertilization leads to gastrulation (form 3 germ layers)
In weeks 3-8 - differentiation of germ layers
Ectoderm - epidermis, nervous tissue, neural tube
Mesoderm - paraxial mesoderm - somites - axial skeleton/muscle/dermis?

How do these somite cells differentiate to form above 3

A

Cells from Somites form :

1) DERMATOME - Dermis
2) MYOTOME - Muscle
3) SCLEROTOME - tendons/cartilage/bone/vertebra

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104
Q

In week 1-3 fertilization leads to gastrulation (form 3 germ layers)
In weeks 3-8 - differentiation of germ layers
Ectoderm - epidermis, nervous tissue, neural tube

**Mesoderm - Intermediate mesoderm
Where are the IM found?
What do they form?

A
  • IM found between PARAXIAL and LATERAL plate mesoderm)
  • forms UROGENITAL structures (parts of urinary system and somatic parts of gonad)

**GERM CELLS
-PRIMORDIAL germ cells arise from EPIBLAST
(In caudal part)
-Migrate through primitive streak to YOLK SAC
-eventually migrate to genital ridge

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105
Q

In week 1-3 fertilization leads to gastrulation (form 3 germ layers)
In weeks 3-8 - differentiation of germ layers
Ectoderm - epidermis, nervous tissue, neural tube

**Mesoderm - Lateral mesoderm - parietal/somatic and visceral/splanchnic
What do these parts form?

A

SOMATIC/PARIETAL

  • forms BODY WALL
  • DERMIS of body wall
  • Bones and CT of limbs and sternum
  • Lining of intraembryonic cavity

VISCERAL/SPLANCHNIC
-Covers organs (forms MESOTHELIUM)

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106
Q

In mesoderm,

1) What does lateral folding of the embryonic disc create?
2) How are blood cells/islands formed? Where and when?
3) What is main site of hematopoises from 2-7 months?
4) What is responsible for hematopoiesis after 7 months?

A

1) Between weeks 3-4, lateral folding of embryonic disc creates the INTRAEBRYONIC CAVITY and closes the wall of the gut
2) Blood islands formed by HAMANGIOBLASTS appear in the Mesoderm of wall of YOLK SAC beginning in week 3
3) LIVER
4) STEM cells in BONE MARROW

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107
Q

In mesoderm,

1) How are blood vessels formed?
2) What is the common precursor for both blood cells and vessels?
3) What are the 2 mechanisms?

A

1) Blood vessels are formed from mesoderm cells that differentiate into hemangioblasts
2) HEMANGIOBLASTS
3)
- Vasculogenesis : blood vessels/endothelial cells derived from BLOOD ISLANDS
-Angiogenesis : Sprouting of vessels from existing vessels

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108
Q

Name the condition of mesoderm

  • Excessive growth of blood vessels
  • Most common tumor in infants
  • Can cause secondary problems

What is the tx?

A

HEMANGIOMAS

-Tx with prednisone/surgery if bad

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109
Q

In mesoderm, As the neural tube is forming, what forms alongside?

What region?

A

**Formation of the heart

-folding of the cranial region due to growth of the neural tube brings the developing heart into the THORACIC REGION

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110
Q

In mesoderm,

1) How does head and tail fold?
2) What does this result in ?
3) What will it form?
4) what will it pull?

A

1) Head and tail fold VENTRALLY
2) Ventral fold in combination with LATERAL folding CLOSES the body wall
3) Forms gut and yolk sac becomes VITELLINE DUCT
4) Pulls amnion completely around embryo

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111
Q

What are the derivatives of Endoderm?

A
  • Epithelial lining of the GI tract, lung, urethra, bladder
  • Parenchyma of thyroid, parathyroid, liver and pancreas
  • Stroma of tonsils and thymus, parts of ear
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112
Q

1) What happens at the end of week 8?

2) what is the period from 3 months to birth called? What happens here?

A

1) All organ systems are DEVELOPED, but need further growth and maturation

2) FETAL PERIOD
- growth in length and weight

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113
Q

How do you calculate gestational age under the following timelines:

1) Pregnancy
2) Embryonic period
3) Fetal period

A

1) Pregnancy
- 266 days or 38 weeks after fertilization
- 280 days or 40 weeks after the first day of LMP

2) Embryonic period (week 3-8)
- SOMITE number

3) FETAL period (week 8-38)
- crown to rump length
- crown to heel length
- other : head circumference and femur length

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114
Q

In the 3 time periods, when is the risk of birth defects highest? Lowest ?

When is the first prenatal visit?

A

-HIGHEST risk of birth defects in EMBRYONIC PERIOD (Week 3-8)

**First prenatal visit is WEEK 8

  • LOWEST RISK (Week 1-3 and Weeks 8-38)
  • Fetal period is week 8-38
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115
Q

What are the different imaging modalities for Ionizing and Non-Ionizing radiation?

A

1) Ionizing radiation
- Radiographs (x-rays, conventional films, plain films), fluoroscopy - real time moving X-ray
- CT (computer tomography)
- NM (nuclear medicine - use radio-tracers)

2) Non-Ionizing radiation
- MRI (Magnetic Resonance Imaging - use radio waves)
- US (Ultrasound - use sound waves)

116
Q

Describe the events that led to the birth of radiology?

Who discovered X-ray?
WHen?

A
  • Nov 8th 1895 : Wilhelmina Conrad Roentgen discovered X-RAY
  • He termed this new INVISIBLE ray x-ray (x=unknown)
  • Received 1st Nobel price in physics in 1901
  • Widespread use for medical imaging by 1913
117
Q

Name the imaging modality

  • Images produced through the use of Ionizing radiation but WITHOUT added contrast material i.e barium or iodine
  • X-rays are passed through the patient and detected on the other side by film or digital detector
  • Images are named with consideration to the direction of the X-ray beam
A

CONVENTIONAL RADIOGRAPHS/Plain films

118
Q

What are the 3 common radio graphic projections?

A

1) AP - anterior posterior
2) PA - posterior anterior (chest films)
3) Lateral (from side profile view)

119
Q

An example of ionizing radiation modality is radiographs. Radiographs can be x-rays that use ionizing radiation without the use of contrast material (barium or iodine)

  • X-rays are absorbed based on the DENSITY of the tissue as they past through the body.
  • This difference in absorption produces an image

-What are the different images that can be produced?

A

1) Radiopaque/Radiodense : WHITE IMAGE. A totally OPAQUE or DENSE material will absorb all the X-rays, allowing none to pass through. E.g Lead/metal
2) Radiolucent - BLACK IMAGE. Less dense material is between the source and the film so MORE X-RAYs strike the film e.g Air
3) GRAY IMAGE - intermediate degrees of transparency e.g fat and soft tissue

120
Q

Name the 5 basic densities on radiographs (Ionizing radiation) and give examples of each

A

1) Air - RADIOLUCENT (black) - absorbs the LEAST x-ray and appears blackest on conventional radiographs
2) Fat - (dark grey)
3) Soft tissue (muscle), fluid (blood)- (light grey)
4) Bone - (Lightest grey/closer to white) most dense naturally occurring material absorbs MOST x-rays
5) Metal - RADIOPAQUE (white) absorbs ALL x-rays e.g bullets, barium

121
Q

How many views and needed for an Ionizing radiation (conventional radiography) and why?

A

MULTIPLE VIEWS (AP, PA, lateral)

  • radiographs are 2D projections of a 3D patient
  • Radiographs flatten everything
  • Multiple views are needed
122
Q

Name 4 advantages and 3 disadvantages of Plain films (Ionizing radiation)

A

Advantages

  • FAST
  • relatively INEXPENSIVE to produce
  • can be obtained almost ANYWHERE using portable or mobile machines
  • are still the most widely obtained imaging studies

Disadvantages

  • Utilizing ionizing radiation
  • soft tissue is hard to visualize or can’t be visualized at all
  • Not recommended for pregnant women except in emergency
123
Q

Name the mating modality

  • continuous beam of x-rays passes through the patient t give a MOVING, REAL-TIME image
  • used in conjunction with CONTRAST (barium, iodine)
  • constraint helpful to evaluate MOTION in intestinal tract or angiographic studies
  • Also used for catheter and tube placement, fracture repair, apparatus placement in SURGERY
A

FLUOROSCOPY (Ionizing radiation)

124
Q

Name the imaging modality?

  • introduced in 1972 by British engineer GODFREY HOUNSFIELD
  • more sensitive x-ray detection system which creates slice images through the body
  • allow capability to see through the SKULL into the brain
A

COMPUTED TOMOGRAPHY (CT)

**HOUNSFIELD UNITS is the scale used to measure CT density

125
Q

What makes CT (computed tomography) different or similar from radiography?

A
  • similar to radiography in that it uses IONIZING RADIATION. From a source to produce an image
  • source and detector rotates 360 degrees around the patient
  • computer uses a number of algorithms to construct 3D information in 2D slices
126
Q

What are the different views of CT?

What makes it have different planes?

A

-because data is MULTI-PLANAR, images can be reconstructed in different planes

SAGITTAL view (L/R) 
CORONAL view (Front and back) 
TRANSVERSE/Axial view (Horizontal)
127
Q

How are CT density numbers measured?

A

-CT density numbers are measured using the HOUNSFIELD Scale
-the CT number varies according to the density of the tissue scanned (the more dense, the higher the CT density number)
E.g air is -1000 HU and
Bone is 400 to 600 HU

128
Q

On a CT scan, what is the relationship between density, attenuation and absorbance

A

1) Denser substances absorb MORE X-RAYS have HIGH CT numbers, demonstrate INCREASED ATTENUATION and display WHITER DENSITIES e.g bone
2) Less dense substances that absorb FEWER x-rays have LOW CT numbers, demonstrate DECREASED ATTENUATION and display BLACKER DENSITIES on CT scans e.g air

129
Q

What is this called when different window settings on the computer optimize the visibility of different types of pathology after the images are obtained (e.g bone window lung window)

Give examples

A

POST-PROCESSING

  • BRAIN WINDOWS allow evaluation of brain parenchyma, hemorrhage, CSF spaces and soft tissue at the expense of bony detail
  • BONE WINDOWS allow detailed examination for FRACTURES but obscure all SOFT TISSUE detail
130
Q

Contrast or No-contrast with CT scan

A

CONTRAST

  • Contrast-enhanced or enhanced
  • Yield more diagnostic information that is more easily recognization
  • radiographic contrast agents administered to increase the differences in density between two tissues

Contrast Reactions
-IV contrast containing high iodine opacity tissues and organs to appear WHITER on images; excreted in the urine by KIDNEYS

131
Q

The following reactions can occur from what modality?

-Patient with diabetes, dehydration, multiple myeloma who have compromised RENAL FUNCTION, can end up having NEPHROTOXIC EFFECT resulting in acute tubular NECROSIS

What can this result to?
What are the side effects?

A

CONTRAST-ENHANCED CT Scans

  • *acute tubular necrosis is often reversible but a small number of patients with underlying renal insufficiency can have their renal dysfunction permanently worsen
  • *Mild side effects - nausea, vomiting, local irritation at the site of injection, itching and hives
132
Q

What are the advantages and disadvantages of CT

A

Advantages
-Excellent resolution for many areas (can see FRACTURES otherwise missed)
0can see multiple planes
-Widely available
-Cheaper than MRI
-Fast (few seconds for whole body)
-Grey scale can be manipulated on viewing screen

Disadvantages

  • High radiation doses
  • can require IV contrast (1% are allergic to CT contrast, can affect renal function)
  • cost more than radiographs
    • knee radiographs (4 views) - $154
  • *Knee CT (no contrast) - $1,200
133
Q

Who discovered MRI and how was it discovered

A
  • NIKOLA TESLA discovered the rotating magnetic field in 1882 in BUDAPEST, HUNGARY.
  • Fundamental discovery in physics
  • In 1956, the “Tesla Unit” was proclaimed by the international electro-technical commission committee of action.
  • All MRI machines are calibrated in “Tesla Units”.
  • The strength of a magnetic field is measured in Tesla or Gauss Units
  • First MRI performed in 1977 on a human beings for 5 hours
134
Q

Name the imaging modality

  • The patient is placed within the bore of a powerful magnet that passes radio waves through the body in a particular series of very short pulses
  • Each pulse causes a responding pulse to be emitted from the patient
  • A computer manipulates the data which produces an image
A

MRI - Magnetic Resonance Imaging

135
Q

What is the magnetic field strength of most MRI scanners today?

How does this differ in comparison with open MRI scanners?

What is the relationship between field strength magnets and spatial resolution?

A
  • Most scanners today have a magnetic field strength between 0.6 and 3 TESLA
  • Open MRI scanners have LOWER field strength of 0.1 - 1.0 T
  • In general, HIGHER field strength magnets have BETTER spatial resolution but are MORE expensive to install and operate compared with LOWER field strength magnets
136
Q

How do weighted Images differ with MRI scans \

What are images weighted?

A

-Images weighted to enhance different characteristics of the soft tissue

    • WATER will be DARK on T1-weighted images and BRIGHT on T2-weighted images
    • FAT is bright on bth T1 and T2

T1 - Show ORGANS best
T2 - more sensitive for pathological lesions (fluid and blood)

Increased (high) signal intensity = white or bright area
Decreased (low) signal intensity = black or dark area

137
Q

What are the advantages and disadvantages of MRI

A

Advantages

  • No ionizing radiation
  • can scan multiple planes (axial, coronal, SAGITTAL)
  • Better soft tissue detail than CT

Disadvantages
-Images CAN NOT be manipulated on the viewing screen like CT
-Narrower than CT, worse for claustrophobic or larger patients
-Noisy
-Can’t be scanned if you have certain kinds of METAL/IMPLANTS
-No movement allowed
-Adverse reactions to contrast
-Long (30-60 minutes)
**need to lie still the entire time, need to reschedule if coughing/sneezing, poor images of abdomen due to breathing and peristalsis (CT of abdomen is better)
-Expensive
*Coils $25k
Scanners $2million
Need specialty trained technologist
Limited number of patients scanned per day
Knee MRI is $2400

138
Q

What are the things you can’t bring into an MRI scanner room?
Why?

What are the safety/NOn- safety issues?

A

Anything :

  • Ferromagnetic
  • Electronic
  • Not certified MRI compatible

**The MAGET is ALWAYS on

Safety Issue

  • Metal that CAN MOVE
  • Metal in/around he eyes
  • OLD ANEURYSM CLIPS

Non-Safety Issue

  • Metal that CAN NOT move
  • FILLINGS in TEETH
  • ORTHOPEDIC hardware

**Pacemaker is an Issue because the MRI scan can ; drain the battery, make pacer fire erratically, scramble electronics or reprogram pacer

139
Q

In patients with renal insuffciency, gadolinium-based contrast agents have been associated with a rare, painful, debilitating and sometimes fatal disease called?

A

NEPHROGENIC SYSTEMIS FIBROSIS (NSF)

  • NSF produces fibrosis of skin, eyes, joints and internal organs resembling SCLERODERMA
  • Patients with preexisting renal dysfunction, especially those on dialysis are at greatest risk
  • Caution is exercised when administered get gadolinium to patients who have moderate renal disease and typically avoided in patients with severe renal disease
  • Currently NO EVIDENCE to suggest that patients with normal renal function are at risk of developing NSF and contrast - enhanced MRI imaging remains extremely safe in the vast majority of patients
140
Q

Name the imaging modality

  • Employs a transducer that produces high frequency sound waves
  • Sound reflected by body structures and is recorded by the transducer and converted to GREY IMAGE

What are the different image types?

A

ULTRASOUND (US)

1) SONODENSE - Increased echogenicity (tissue that reflects many echoes and appears BRIGHT/WHITE) e.g bones, stone, fat
2) SONOLUCENT - Decreased echogenicity (tissue that has few or no echoes and appear DARK or BLACK) e.g lymph nodes, tumors

141
Q

What is Ultrasound usually used for preferentially?

A
  • usually study of first choice in imaging the FEMALE PELVIS and PEDIATRIC patients
  • differentiating CYSTIC versus SOLID lesions in all patients
  • Noninvasive vascular imaging
  • Imaging of the fetus and placenta during PREGNANCY (It is SAFE)
  • Real-time, image-guided fluid aspiration and biopsies
142
Q

What are the advantages and disadvantages of Ultrasound?

A

Advantages

  • No ionizing radiation
  • Real-time images
  • Produces little to no patient discomfort
  • Easy to use and noninvasive
  • Inexpensive
  • Portable

Disadvantages

  • Bone and air-filled structures interfere with image
  • Difficulty penetrating obese patients
  • You can’t do an ultrasound of the skull except in a baby where the skull isn’t there yet)
143
Q

Name the imaging modality

-Uses radioactive isotopes attached to normal physiologic chemical substances to visualize particular living organs and tissues

A

RADIONUCLIDE IMAGING (NUCLEAR IMAGING)

  • offer potential to identify disease in the earliest stages as well as patient immediate response to therapeutic intervention
  • Radioactive material called RADIOTRACERS injected into the bloodstream (inhaled or swallowed)
  • Radiotracer travels through examined area and give off gamma rays detected by a special camera and a computer to create images
  • DETECT FRACTURES FAST
144
Q

Name the imaging modality

-Screening method of choice for the detection of osseous metastatic disease and for diagnosing fractures before they become visible in conventional radiography

A

BONE SCANS

  • uses technetium-99m attached to organic phosphate to find areas of increased uptake due to osteoblastic activity (increased blood flow and inflammation)
  • After the IV injection, most of the dose is uickly extracted by the bone.
  • The remaining radiopharmaceutical is excreted by the KIDNEYS and collects in the urinary bladder
145
Q

What are the advantages and disadvantages of Nuclear Medicine?

A

Advantages

  • excellent SPECIFICITY
  • provides physiologic information
  • provides EARLY DETECTION

Disadvantages

  • EXPENSIVE
  • Availability of service
  • radiation
  • poor spatial resolution
146
Q

What does radiation exposure result in?

A
  • Ionizing radiation in Large doses, (higher than medically radiographic procedure) can produce CELL MUTATIONS that lead to many forms of CANCER and anomalies
  • Only medically necessary diagnostic examinations should be performed
  • Shield the most radiation sensitive areas (Gonads, eye lens, thyroid)
  • X-rays should be avoided in PREGNANCY
147
Q

What is the average background radiation dose?
Chest radiograph?
Chest CT?

A

1) Background radiation - present in environment
Approx 2.4 mSv/yr

2) Chest Radiograph - approx 0.08 mSv (about 1 week of background radiation)
3) Chest CT - approx 7.0 mSv (about 3 years of background radiation)

***50mSv for single procedures or 100mSv for multiple procedures over short time periods are too LOW to be detectable and may be non-existent

148
Q

What are the routine views of the Hip?

A

1) AP
2) Lateral/frog view

**The femurs should be INTERNALLY ROTATED (15 degree)when obtaining an AP PELVIS FILM so as to display the femoral necks in profile

149
Q

What differentiate a normal AP film from a Femur FRACTURE?

A

Normal AP film
-SHENTON’s line (formed by the medial edge of the femoral neck and the inferior edge of the superior public ramps)

FEMORAL Neck fracture

  • frequently related to OSTEOPOROSIS
  • AVASCULAR necrosis of the femoral head occurs in 10-30% of subcapital fx due to disruption of the blood supply
  • DISRUPTED SHENTON’s LINE
  • SHORT NECK
  • Zones of INCREASED DENSITY indicating impaction
150
Q

A man is rushed into the ER from an automobile accident because his knees impacted the dashboard badly. What is the likely diagnosis?

What would the radiography look like?

A

POSTERIOR HIP DISLOCATION

  • More than 90% of all hip dislocations
  • Most common mechanism is high-energy trauma
  • In 10% of patients, sciatic nerve is injured
  • Radiographic features:
  • Femoral HEAD LATERAL and SUPERIOR to acetabulum
  • Femur in INTERNAL ROTATION and ADDUCTION
  • Affected femoral HEAD appears SMALLER
  • Fracture of the posterior rim of the acetabulum may occur
151
Q

What is the diagnoses form this radiography

  • Femoral Head MEDIAL and INFERIOR to the the acetabulum
  • Femur in EXTERNAL ROTATION and ABDUCTION
  • Affected femoral head may appear LARGER
A

ANTERIOR HIP DISLOCATION

152
Q

What are the routine views of the Knee

A

1) AP
- Good when looking for signs of osteoarthritis which include; joint space narrowing, osteophyte formation and SUBCHONDRAL CYSTS

2) Lateral
- Good for evaluating the PATELLA
- determine presence of effusion which is often seen in joint cavity superior to the patella (SUPRAPATELLAR BURSA)

153
Q

1) Why are knee injuries common?
2) What are the most commonly injured structures
3) How best evaluated
4) What is the next most common injury?

A

1) Knee injuries are most common due to LARGE SIZE and COMPLEXITY of the KNEE
2) Most commonly injured are the SOFT TISSUE and CARTILAGINOUS structures including ligaments and menisci
3) Best evaluated CLINICALLY or by MRI
4) Next most common injury are FRACTURES - occurring much more often than dislocation

154
Q

What is the diagnoses

-Common knee injury usually from direct trauma to the site or sudden forceful contraction of the uadriceps muscles in a context of sport injury

A

PATELLA FRACTURE by blunt force trauma

155
Q

Name this
Is it normal?

  • Patella with infused accessory ossification center
  • Bilaterally symmetrical
  • Occur at anatomically predictable sites i.e upper lateral aspect of patella
  • Smooth corticated edges
A

BIPARTITE PATELLA

156
Q

Name this
Is it normal?

-A SESAMOID BONE sometimes present in tendon of origin of the lateral head of the gastrocnemius muscle

A

FABELLA

**Normal variant - can be mistaken for fracture

157
Q

Name the routine views of the lower leg

A

1) AP

2) Lateral

158
Q

What is the common site for Stress fractures?

A

TIBIA

** Imaging show transverse lucency in the cortex surrounded by cortical thickening

159
Q

What are the routine views of the ANKLE

A

1) AP
2) Lateral
3) MORTISE VIEW
- AP view with 15 to 20 degree internal rotation of the foot
- lateral malleolus about same height as the medial malleolus
- Both the lateral and medial joint spaces are visualized
- Talus DOES NOT overlap portion of lateral malleolus unlike the true AP that obscures the lateral aspect of the ankle joint

160
Q

What is the most commonly injured of all the weight bearing joints in the body

A

ANKLE

-In case of ligament damage without fractures, seen on plain film as soft tissue swelling over the injury

161
Q

What are the routine views of the Foot

A

1) AP
2) Internal Oblique
3) Lateral

162
Q

Name the diagnosis

  • result of microfractures from repeated stretching and compressive fractures
  • Plain film first obtained ; may appear normal 85% of the time
  • Radionuclide bone scans usually positive within 6-72 hours after the injury
A

STRESS FRACTURE of the FOOT

**Most common location for a stress fracture of the foot is the 2nd or 3rd metatarsal also called MARCH FRACTURE

163
Q

Name the diagnosis

-CHILD with extra small piece of bone oriented longitudinally along the long axis of the shaft of the metatarsal

What is it in ADULT?

A

APOPHYSIS of the proximal 5th metatarsal

**appears on plain radiographs at age 12 for boys and 10 for girls and fuses 2-4 years later

-In ADULT ; UNFUSED Accessory ossification center of the proximal 5th metatarsal

164
Q

Name the diagnosis

  • Avulsion fracture at the base of the 5th metatarsal, at the insertion of the PERONEUS BREVIS tendon
  • Almost always oriented TRANSVERSELY across the long axis of the shaft
  • Frequently caused by PLANTAR FLEXION of the foot and INVERSION of the ankle i.e mis-stepping from a curb
A

PSEUDO-JONES FRACTURE

165
Q

1) WHat are the cell types found in cartilage?
2) What is the blood supply
3) How do cells acquire nutrients and eliminate wastes?

A

1) CONDROBLASTS and
CONDROCYTES
2) AVASCULAR (get nutrient by DIFFUSSION)
3) High water content - all nutrients enter and metabolites leave cartilage by diffusing through the ECM

  • similar to CT (cells, fiber, matrix)
  • Develop from primitive mesenchymal cells
  • Fibers and matrix depend on type of cartilage (Hyaluronic acid and GAGs)
  • Soft and pliable
  • Provides support for soft tissues
  • resist compression (acts as SHOCK ABSORBER)
  • Template for bone development
166
Q

Name the following cells of cartilage respectively

1)
- Divide MITOTICALLY
- Synthesize the cartilage Matrix and extracellular material around them
- As the cartilage model grows, the individual cells become surrounded by the ECM and trapped in matrix compartments called LACUNAE

2)
- MATURE cartilage cells
- Found in the lacunae
- Main function is to maintain the cartilage matrix
- ISOGENOUS GROUPS -groups of the cells

A

1) CHONDROBLASTS
* mesenchymal cells differentiate into chondroblasts and fibroblasts
* fibroblasts form the perichondrium

2) CHONDROCYTES

167
Q

Mesenchymal cells can also differentiate into fibroblasts that form what?

  • A DENSE IRREGULAR CT layer that invests the cartilage
  • VASCULAR
  • Formed from FIBROBLASTS
  • INNER cellular layer contains CHONDROGENIC CELLS which can differentiate into condroblasts, secrete cartilage matrix and become trapped in lacunae as condrocytes
  • PERIPHERAL layer contain Dense vascular connective tissue and type 1 collagen
  • Found on peripheries of HYALINE (except articular) and ELASTIC CARTILAGE
A

PERICHONDRIUM

  • The inner cellular layer contains CHONDROGENIC CELLS
  • can differentiate into chondroblasts
  • secrete the cartilage matrix
  • become trapped in LACUNAE as chondrocytes
168
Q

WHat type of cartilage is this ?

  • Developing skeleton of embryo
  • epiphyseal plate of growing bone (replaced by bone during endochondral ossification)
  • Articular cartilage (Knee joint, No perichondrium)
  • End of ribs, respiratory tract
  • Provides a firm structural and flexible support
  • Numerous branching elastic fibers in its matrix (confers structural support and increased flexibility)
  • can CALCIFY with aging
  • MOST COMMON in the body
  • serves as a SKELETAL MODEL for most bones
  • TYPE II COLLAGEN
A

HYALINE CARTILAGE

**TYPE II COLLAGEN, proteoglycans (contain water)
MOST COMMON TYPE
Glassy appearance 
PERICHONDRIUM 
MODEL TEMPLATE for growth of skeleton
169
Q

What type of cartilage is this?

  • Found in Ear, epiglottis, Eustachian tube, larynx,
  • TYPE II COLLAGEN
  • Elastic fibers (Make the cartilage much more flexible so it can bend without breaking)
  • PERICHONDRIUM
  • Matrix DOES NOT calcify with aging (Maintains its high flexibility)
  • Contains branching elastic fibers
A

ELASTIC CARTILAGE

170
Q

What type of cartilage is this? (HiNt 3 types)

  • INTERVERTEBRAL DISCS ; annulus fibrosis
  • MENISCUS of knee, mandible, sternoclavicular joints, pubic symphysis
  • TYPE II collagen
  • TYPE I collagen in dense regular pattern (help provide additional tensile strength)
  • Cells in ROWS (CHONDROCYTES and fibroblasts)
  • Provides tensile strength (resist BOTH compression and stretching)
  • Bears weight
  • NO PERICHONDRIUM
A

FIBROCARTILAGE

171
Q

There are 2 possible ways cartilage can grow : appositional growth and interstitial growth. Identity the type of growth and where it occurs

  • Cells from the inner layer of perichondrium differentiate into CHONDROBLASTS
  • Deposit matrix next to existing matrix
  • INCREASES cartilage WIDTH
A

APPOSITIONAL GROWTH

**Occurs on the PERIPHERY of the cartilage

172
Q

There are 2 possible ways cartilage can grow : appositional growth and interstitial growth. Identity the type of growth and where it occurs

  • Growth of chondroblasts by MITOSIS within the cartilage matrix
  • New territorial matrix deposited (btw and around the newly formed cells)
  • INCREASES cartilage growth and size from WITHIN (LENGTH AND WIDTH)
  • forms ISOGENOUS groups (groups of chondrocytes)
A

INTERSTITIAL GROWTH

173
Q

SUMMARY TABLE
3 types of cartilage

Cell organization: Which type has cells in ROWS

A

FIBROCARTILAGE

Condrocytes and fibroblasts

174
Q

SUMMARY TABLE
3 types of cartilage

Matrix

1) Which type has Type II collagen
2) Which has Type I collagen

A

1) All have type II - Hyaline, elastic, FIBROCARTILAGE

2) Only FIBROCARTILAGE has Type I

175
Q

SUMMARY TABLE
3 types of cartilage

Which has elastic fibers?

A
  • Hyaline (branching elastic fibers)

- Elastic (elastic fibers)

176
Q

SUMMARY TABLE
3 types of cartilage

What is the vascular supply?

A

All are AVASCULAR (get nutrient by diffusion)
Hyaline
Elastic
FIBROCARTILAGE

177
Q

SUMMARY TABLE
3 types of cartilage

Which has PERICHONDRIUM

A
  • Hyaline (except Articular cartilage)
  • Elastic

FIBROCARTILAGE HAS NO Pericondrium

178
Q

SUMMARY TABLE
3 types of cartilage

Which is located in the ear, epiglottis, Eustachian tube and larynx

A

ELASTIC CARTILAGE

179
Q

SUMMARY TABLE
3 types of cartilage

Which is located in the epiphyseal plate of growing beings, Articular cartilage, ends of ribs, respiratory tract

A

HYALINE CARTILAGE

180
Q

SUMMARY TABLE
3 types of cartilage

Which is located in intervertebral discs, meniscus of knee, mandibles, sternoclavicular joints, pubic symphisis

A

FIBROCARTILAGE

181
Q

SUMMARY TABLE
3 types of cartilage

Which function to

  • provide firm structural and flexible support
  • serves as a skeletal model for most bones
A

HYALINE CARTILAGE

182
Q

SUMMARY TABLE
3 types of cartilage

Which function to
-Make the cartilage muscle more FLEXIBLE so it can BEND without breaking

A

ELASTIC CARTILAGE

183
Q

SUMMARY TABLE
3 types of cartilage

Which function to

  • provide tensile strength
  • resist both compression and stretching
  • bears weight
A

FIBROCARTILAGE

184
Q

What is this ?

  • consist of cells, fibers and matrix
  • mineral deposits make bone stronger
  • Functions : weight bearing, attachment of muscles protection of internal organs, site of HEMATOPOIESIS, reservoir for minerals (CALCIUM)
A

BONE

185
Q

There are 2 possible bone structures

Identify which is which
1) LESS dense, lines marrow cavities, at the END of LONG BONEs, arranged in trabeculae (spicules) to create more surface area

2) DENSE bone on the OUTSIDE of LONG BONES, ARRANGED IN LAMELLAE (OSTEONS)
- found in cortex
- contains concentric layers (lamellae) of cells and matrix around a central canal

A

1) CANCELLOUS (spongy or trabecular)

In long bones

  • In center/medulla of the bone
  • Contains irregular arrangement of cells and matrix forming TRABECULAE

In flat bones (Skull and sternum)
-In center/medulla of bone

2) COMPACT BONE

186
Q

There are 5 parts of long bone
Identify each
1) Articular cartilage, spongy bone, RED bone marrow
2) Epiphyseal line, spongy bone, RED bone marrow, bone deposition occurs
3) COMPACT bone, YELLOW bone marrow, shaft, medullary cavity (marrow) , has periosteum and endosteum
4) region of growth plate where bone deposition occurs
5) Articular cartilage

A

1) PROXIMAL epiphysis
2) Metaphysis
3) Diaphysis
4) Metaphysis
5) Distal epiphysis

  • **Epiphysis is at the ends of the long bones
  • articular cartilage growth plate extends the length of bones
  • epiphyseal line is remnant of the growth plate
187
Q

What is this?

  • Provides nutrition for the bone
  • Continuous supply of new osteoblasts for growth, remodeling and bone repair
  • found on the diaphysis/shaft of long bone
A

PERIOSTEUM

188
Q

What is this?

  • Single layer of cells lining INNER body surfaces
  • Functions to : provide nutrition for the bone and continuous supply of new osteoblasts for growth, remodeling and bone repair
A

ENDOSTEUM

189
Q

Identify which of the 4 bone cell types

  • Undifferentiated, pluripotent stem cells derived from MESENCHYME
  • stem cells that give rise to OSTEOBLASTS
  • squamous cells
  • Found lining the bone in the periosteum and endosteum
A

OSTEOPROGENITOR CELLS

190
Q

Identify which of the 4 bone cell types

  • Derived from OSTEOPROGENITOR CELLS
  • CUBOIDAL epithelial like cells
  • Form new bone (BONE FORMING)
  • secrete OSTEOID
  • contribute to mineralization
  • present on the SURFACES of bone
A

OSTEOBLASTS

  • *secrete OSTEOID
  • Organic components of the new bone matrix (TYPE I COLLAGEN fibers, several glycoproteins, proteoglycans)
  • Uncalcified
  • DOES NOT contain any minerals
  • Shortyly after its deposition, it is rapidly mineralized and becomes hard bone
191
Q

Identify which of the 4 bone cell types

-Mature forms of OSTEOBLASTS that become surrounded by the mineralized bone matrix
-Osteoblasts that become trapped in OSTEOID
-SMALLER than osteoblasts
-become principal cells of the bone
Reside in LACUNAE (remodeled bone)
-contribute to CALCIUM and PHOSPHATE homeostasis

A

OSTEOCYTES

  • In contrast to cartilage, only 1 osteocyte is found in each bony LACUNA
  • Because mineralized bone matrix is much harder than cartilage, nutrients and metabolites CANNOT freely diffuse through it to the osteocytes (Bone is highly VASCULAR, canaliculi)
  • GAP JUNCTIONS (connect highly branched cells with processes to their osteocytes through CANALICULI)
192
Q

Identify which of the 4 bone cell types

  • Derived from MONOCYTES/MACROPHAGE lineage (large and multinucleated)
  • Found along BONE SURFACES where resorption, remodeling and repair of bone take place
  • Reside in HOWSHIP LACUNAE
  • respond to hormones to satisfy the body’s needs for calcium
  • BREAKDOWN bone during remodeling
A

OSTEOCLASTS

  • reside in HOWSHIP LACUNAE
  • shallow depressions in the bone matrix
  • Enzyme-eroded depressions
  • BREAKDOWN BONE
  • creases an acidic environment that causes dimineralization (H-ATPase)
  • organic compounds degraded enzymatically
193
Q

Name the following components of bone

1) What is the collagen type?
2) Organic component?
3) Inorganic component?
4) Blood supply?

A

1) TYPE I collagen fibers
2) Organic component
-OSTEOID
(Proteoglycans, Non-collagenous proteins; osteopontin, osteocalcin, osteonectin, bone sialoprotein).
-RESIST TENSION
3) Inorganic component
-CALCIUM PHOSPHATE
-RESIST COMPRESSION
4) Highly vascularized with blood vessels from periosteum to aid diffusion through calcified matrix

194
Q

Bone can be prepared in 2 ways;

Which is which

  • Bone is soaked in a weak acid to REMOVE CALCIUM
  • The soft block is sectioned for slides as usual
  • Cells are left intact but structure is hard to see
A

DECALCIFIED BONE

195
Q

Bone can be prepared in 2 ways;
Which is this?

  • A SMALL BLOCK of bone is ground down thin
  • Dipped in ink to show structure is visible (cellular components are destroyed by process)
  • can see osteons well
A

GROUND BONE

196
Q

Tell me about Osteon (haversian system)

A

-In compact bone
-Composed of lamella/rings surrounding a Haversian canal and the canal itself
-LAMELLA, surrounding the blood vessels and loose CT
-maintained by a single capillary in Haversian canal
-mostly run lengthwise/longitudinally in a long bone
-circumferential lamella on outer and inner surface
-interstitial lamella
(Partial osteons in the middle of the compact bone, remnants of former osteons from remodelling process

197
Q

Tell me about volkmann’s canal

A
  • Canal that runs transversely across the long axis of the long bone
  • Carry capillaries that interconnect longitudinal haversian capillaries or carry capillaries into the bone from periosteum
198
Q

There are 2 mechanisms for bone formation. WHICH IS which

1)
- forms directly in mesenchyme
- process used to form skull bones, parts of mandible and clavicles

2)
- forms in cartilage templates
- process used to form long bones

A

1- INTRAMEMBRANOUS OSSIFICATION
2- ENDOCHONDRAL OSSIFICATION

**Both begin by forming TRABECULAE of spongy bone (later remodeled into compact bone)

199
Q

Identify which ossification mechanism is used for bone formation

  • During fetal development
  • mesenchyme (primitive CT)
  • mesencymal cells are pluripotent stem cells (fibroblasts, CHONDROBLASTS, osteoblasts)
  • mesenchyme becomes VASCULARIZED
  • Aggregrates of mesenchymal cells differentiate into osteoblasts
  • Osteoblasts secrete OSTEOID to form an ossification center
  • ossification center enlarge and fuse to form TRABECULAE
  • Trabeculae continue to enlarge by APPOSITION GROWTH
  • CALCIUM PHOSPHATE is deposited in OSTEOID
  • entrapped osteoblasts become osteocytes
  • bones formed are; mandible, maxilla, clavicle, flat SKULL bones
A

INTRAMEMBRANOUS OSSIFICATION

  • *Mesenchymal cells - osteoblasts - OSTEOID form ossification center - trabeculae (enlarge by APPOSITIONAL GROWTH)
    • entrapped osteoblasts become osteocytes
200
Q

Identify which ossification mechanism is used for bone formation

-bones of extremities, vertebral column, and pelvis
-most bones develop by this process
-during development, HYALINE CARTILAGE template form first
-chondrocytes at the site of a primary ossification center secrete factors that induce the growth of blood vessels from the perichondrium
-progenitor cells of perichondrium form a collar of bone on the outer part of the shaft (convert perichondrium into periosteum)
-cartilage matrix becomes calcified
-CHONDROCYTES undergo apoptosis as matrix calcifies
(OSTEOPROGENITOR cells differentiate into osteoblasts on the surface of the calcified matrix and deposit osteoid on the cartilage framework)
-blood vessels bring in OSTEOPROGENITOR and hematopoietic stem cells
-INTERSTITIAL GROWTH of cartilage increases in the LENGTH of the template
-cartilage is replaced by bone advancing from the ossification center
-secondary ossification center appears in the epiphyseal after birth
-cartilage remains only at Articular surface and the epiphyseal plate

A

ENDOCHONDRAL OSSIFICATION

201
Q

After ossification process, hw does bone further grow at the epiphyseal plate

A

-After the ossification of the cartilage template is complete, all INCREASE IN LENGTH take place at the epiphyseal plate
-At puberty, the epiphyseal plate is sealed and no further increase in length occurs
-Increase in width occurs by appositional growth from the periosteum and resorption of bone at the endosteum
-bone is continuously remodeled by the action of osteoclasts and osteoblasts
(Must maintain balance of deposition and degrading)

202
Q

In order to maintain a balance of deposition and degradation, bone must be continuously remodeled by the action of osteoclasts and osteoblasts.

Identify which is which

1) Reduced osteoclasts activity resulting in TOO MUCH BONE
2) TOO MUCH DEGRADATION and not enough deposition causes weakness

A

1) OSTEOPETROSIS

2) OSTEOPOROSIS

203
Q

What is the name of the first bone formed?

  • has collagen fibers in random orientation
  • More ground substance
  • less mineralization
  • NONLAMELLAR
  • seen during fetal bone development and bone repair
A

IMMATURE WOVEN BONE

204
Q

Dense immature woven bone is remodelled not what?

  • Formation of lamella into collagen fibers in regular bundles
  • CONCENTRIC LAMELLAE around the central canal is found in adults
  • collage fibers exhibit parallel arrangements that follow a helical course
  • osteocytes are arranged around the central canal
A

MATURE COMPACT BONE

205
Q

How is bone repaired after a fracture?

A
  • A fracture hematoma forms
  • A fibrocartilaginous (soft callus) forms (regenerating blood vessels) -FROM fibroblasts and OSTEOPROGENITOR cells (help stabilize the fracture)
  • A hard/bony callus forms
  • The bone is remodeled (compact bone at break site)

Fracture hematoma - fibrocartilaginous/soft callus - hard/bony callus - remodeled bone

  • *progenitor cells not close to blood vessels differentiate to CHONDROBLASTS and for cartilage scaffold/skeleton
  • *Progenitors near blood vessels differentiate into osteoblasts and convert cartilage to woven. Bone
  • *Woven bone later converted to lamellar/compact bone
206
Q

What is the thick covering of the thigh called?

What is it attached to superiority?

A

1) FASCIA LATA

2) Superiorly attached to the PELViS, INGUINAL LIGAMENT and SARPA’S FASCIA

207
Q

1) What is the thickened lateral part of fascia LATA called?
2) What is. It’s function?
3) What is the superior and inferior attachment?
4) What inserts into it (2)

A

1) ILIOTIBIAL TRACT (IT Tract)
2)
-Keep knee extended
-Provides lateral stability when standing
-extends legs after other muscles like quadriceps have extended the knee
3)
Superior - Ilium
Inferior - Lateral condole of Femur
4)
Tensor fascia LATA
Gluteus Maximus

208
Q

Name the thigh compartment

Muscle action - EXTEND KNEE (some FLEX HIP)
Nerve - Femoral nerve
Artery - Femoral artery

What are the muscles?

A

ANTERIOR THIGH COMPARTMENT

1) The quadriceps (largest extensor of leg at hip joint)
- RECTUS femoris (bifunctional -flex hip and extend knee)
- VASTUS INTERMEDIUS - extend knee
- VASTUS lateralis ; extend knee
- VASTUS medialis ; extend knee
* All 4 converge on QUADRICEPS TENDON which attaches to patella
2) ILIOPSOAS - Flex hip joint
3) PECTINEUS - flex hip joint
4) SARTORIUS - flex hip joint and flex knee

209
Q

Name the thigh compartment

Muscle action - FLEX KNEE and also EXTEND HIP
Nerve - Tibial part of sciatic nerve
Artery - Perforating arteries

What are the muscles?

A

POSTERIOR THIGH COMPARTMENT

1) HAMSTRING MUSCLES
- semimembranosus; flex knee and extend hip joint
- SEMITENDINOSUS ; flex knee and extend hip joint
- LONG HEAD biceps femoris; flex knee and extend hip joint
- SHORT HEAD biceps femoris; FLEX KNEE ONLY (innervate common perineal part of sciatic nerve)
- Adductor Magnus (Hamstring portion); EXTEND HIP JOINT

  • *EXCEPTION IN Posterior
    2) POPLITEUS - laterally rotate femur (unlock the knee joint)
210
Q

Name the thigh compartment

Muscle action - ADDUCT HIP
Nerve - OBTURATOR nerve
Artery - Profunda femoris artery

What are the muscles?

A

MEDIAL THIGH COMPARTMENT

1) GRACILIS; ADDUCT hip joint and flex knee
2) Adductor longus; ADDUCT hip joint
3) Adductor brevis; ADDUCT hip joint
4) Adductor Magnus (adductor portion); ADDUCT hip joint
* *
5) Adductor Magnus (Hamstring part) ; extend hip joint
* *
6) OBTURATOR externus; laterally rotate femur at hip joint

211
Q

Name the thigh compartment

Muscle action - ABDUCT HIP
Nerve - superior and inferior gluteal nerves
Artery

What are the muscles?

A

LATERAL THIGH COMPARTMENT

GLUTES

1) Gluteus medius; abduct and medially rotate femur
2) Gluteus minimus; abduct and medially rotate the femur
3) Tensor fascia LATA; Abduct femur (also keep leg extended via IT band)

212
Q

What 3 muscles form PES ANSERINUS (goose’s foot)?

What do they insert to?

A

1) SEMITENDINOSUS
2) GRACILIS
3) SARTORIUS

All 3 insert to the TIBIA
*All flex knee

213
Q

What are the 2 muscles of the anterior compartment of the thigh that insert into the FEMUR

A

ILIOPSOAS
PECTINEUS

*BOTH FLEX HIP

214
Q

What is the deepest and largest muscle?

What are the 2 parts?

Origin and insertion?

A

ADDUCTOR MAGNUS

1) Adductor part
- Origin - pubis and ischium
- Insertion; Linea aspera of femur
- Action: ADDUCT thigh
- Nerve: OBTURATOR NERVE

2) Hamstring part
- Origin; ischial tuberosity
- insertion; Adductor tubercle of femur
- Action ; Extends thigh
- Nerve; tibial part of sciatic nerve

***GAP is adductor Magnus is called ADDUCTOR HIATUS

215
Q

1) What are the BORDERS of the femoral triangle?
2) What are the CONTENTS of the femoral TRIANGLE?
3) What does the femoral SHEATH surround?
4) Why is the femoral ARTERY in the femoral triangle IMPORTANT?

A

1)
- Superior; Inguinal ligament
- Medial; Adductor longus
- Lateral; SARTORIUS
- Floor; Adductor longus and PECTINEUS

2) From Lateral to medial (NAVL)
- Femoral Nerve
- Femoral Artery
- Femoral Vein
- lymphatic (in Femoral canal)

3) Femoral sheath is the continuation of TRANSVERSALIS FASCIA; it surrounds femoral artery, femoral vein and femoral canal, NOT FEMORAL NERVE

4)
- site of FEMORAL PULSE and good place for compression of artery (against head of femur and ILIOPSOAS)
- site of insertion of CATHETER FOR ANGIOGRAPHY (cardiac and branches of abdominal aorta)

216
Q

What structure is this?

  • contained in medial part of femoral sheath
  • contains lymph vessels from lower limb that drain to external iliac nodes in abdomen
  • opens superiorly into abdomen; opening is called FEMORAL RING
A

FEMORAL CANAL

217
Q

Name the clinical disorder;

  • Femoral ring is point of potential weakness of abdominal wall
  • loop of bowel can protrude into femoral canal and become strangulated (constricted blood supply)
  • more common in females
A

FEMORAL HERNIA

**Inguina Hernia more common in males

218
Q

How do you differentiate femoral from inguinal hernia?

A

-made by comparing location of neck of hernia (entrance to abdomen) to location of inguinal ligament

  • *Femoral hernia; neck of hernia is BELOW (inferior to) the Inguinal ligament, pubic tubercle
  • *Inguinal hernia; neck of hernia is ABOVE (superior to) the Inguinal ligament, pubic tubercle

**reduce femoral hernia by cutting the inguinal ligaments to push contents back

219
Q

What cutaneous nerves innervate the following

1- femoral
2- OBTURATOR
3- sciatic

A

1- femoral; L2-L4
2-OBTURATOR; L2-L4
3-sciatic; L45, S123

220
Q

What are the cutaneous nerves of the following

A- gluteal region
B- thigh
C-leg
D- foot

A

A; gluteal region
-posterior cutaneous nerve of thigh

B; thigh
1- lateral femoral cutaneous nerve of thigh ; LATERAL side
2- femoral nerve; ANTERIOR side
3- OBTURATOR nerve; MEDIAL side

C; leg
1- saphenous nerve - MEDIAL side form femoral (all remaining branches are from sciatic nerve)
2- Lateral dural cutaneous nerve - lateral side
3- sural nerve - posterior side

D; foot
1- superficial peroneal nerve - dorsal
2- medial and lateral Plantar nerves (from tibial nerve) - sole of foot

221
Q

What is the overview of the arterial supply to the lower extremity?

A

A; left ventricle - Aorta -common iliac arteries - internal (to pelvis) and external iliac artery (to lower extremity)

B; external iliac artery - femoral (inguinal ligament) - popliteal (adductor hiatus) - anterior and posterior tibial arteries

**posterior tibial arteries is main blood supply in FOOT

222
Q

What are the 2 arterial anastomoses and where are they located?

A

1) CRUCIATE anastomosis -located at HIP JOINT (unites branches of internal iliac and femoral artery)
2) GENICULAR anastomoses - located at KNEE JOINT

223
Q

1) what provides most of the blood supply to the head of the femur?
2) What will happen is the artery is damaged?

A

1- MEDIAL femoral circumflex artery
*passes POSTERIORLY btw PECTINEUS and ILIOPSOAS

2- ISCHEMIC NECROSIS OF HEAD OF FEMUR
*medial femoral circumflex artery can be damaged in fracture of neck of femur (broken hip)

224
Q

Name the artery

  • passes laterally, deep to RECTUS femoris
  • supplies lateral side of thigh, neck of femur
  • has DESCENDING BRANCH that is part of genicular anastomosis at knee joint
A

LATERAL FEMORAL CIRCUMFLEX ARTERIES

225
Q

Name the artery

  • important, provide blood supply to posterior compartment of thigh
  • perforate adductor magus muscle
  • located deep, adjacent to femur
A

PERFORATING ARTERIES

226
Q

NAME the artery

  • small branch arises from femoral before entering adductor hiatus
  • part of genicular anastomosis at knee
A

DESCENDING GENICULAR ARTERY

227
Q

What are the 4 parts of cruciate anastomosis?

A

1) Superior -Inferior gluteal artery (from internal iliac)
2) Medial - medial femoral circumflex (from profunda femoris)
3) Lateral - lateral femoral circumflex (from profunda femoris)
4) Inferior - First perforating artery (from profunda femoris)

**femoral artery can be ligated ABOVE the profunda femoris due to cruciate anastomosis which will maintain blood supply around the hip joint BY COLLATERAL CIRCULATION

228
Q

1- what are you doing to your hip and Knee when you move anteriorly
2- what are you doing to hip and knee POSTERIORLY

A

1- flex hip, extend knee

2- extend hip, flex knee

229
Q

Name the disorder

-caused by injury to SUPERIOR GLUTEAL NERVE or POLIOMYELITIS (also congenital dislocation of hip joint)

A

GLUTEAL GAIT/ Positive trendelenburg sign

*Pelvis tilts down on non-paralyzed side when you lift foot of opposite, non-paralyzed leg

230
Q

What nerves and vessels separates the gluteus minimus from gluteus Maximus ?

A

SUPERIOR GLUTEAL NERVES AND VESSELS

231
Q

1) WHAT are bags of fluid that surrounded by connective tissue called?
2) WHat is their function?
3) where is bursae found?

A

1) BURSAE
2) Function as SHOCK ABSORBERS, reduce friction of movement of muscle tendons against bones or other tendons

3) BURSAE are found adjacent to ISCHIAL TUBEROSITY and GREATER TROCHONTER
- trochanter bursae
- ischial bursa

232
Q

Posterior dislocation of hip joint can lead to damage of what nerve?

A

SCIATIC NERVE

-give injection in UPPER LATERAL QUADRANT of gluteal region to avoid damage to sciatic nerve

** sciatic nerve branches to tibial and common peroneal nerve. Early branching leads to PIRIFORMIS SYNDROME (cause pain)

233
Q

What is the wear and stretch of adductor group at Pubis where?

A

PULLED GROIN

234
Q

Name the muscle

  • unlocks the knee joint
  • when you extend the leg, the femur tends to rotate medially, pulling tendons and ligaments taut and locking the knee
  • this muscle acts to ROTATE FEMUR LATERALLY when beginning to flex leg; this unlocks the knee joint
A

POPLITEUS MUSCLE

235
Q

Name the vessel

  • largest branch of femoral artery
  • arises POSTERIORLY in femoral triangle and passes between PECTINEUS and adductor longus
A

PROFUNDA FEMORIS artery

236
Q

Name the vessel

  • passes directly POSTERIORLY between PECTINEUS and ILIOPSOAS
  • provides most of blood supply to HEAD OF FEMUR
A

MEDIAL FEMORAL CIRCUMFLEX artery

237
Q

Name the vessel

  • passes laterally, deep to RECTUS femoris
  • supplies lateral side of thigh, neck of femur
  • has DESCENDING BRANCH that is part of genicular anastomosis at knee joint
A

LATERAL FEMORAL CIRCUMFLEX ARTERY

238
Q

There are 5 main joints in the lower extremity; Knee joint, hip joint, flints between tibia and fibula, ankle joint and joint of inversion and eversion of foot.

Name this joint

  • synovial ball and socket articulation between head of femur and acetabulum,
  • specialized for support of body weight but allows freedom of movement
  • has 3 features ; Articular surfaces, joint capsule, ligament of head of femur
A

HIP JOINT

239
Q

1) What is the C-shape articular surface of acetabulum called?
2) what is the inferior gap ?
3) what deepens the cavity of acetabulum? What other function?
4) what ligament strengthens the Deepened cavity?
5) the articular surfaces of the acetabulum and femur are covered with what cartilage?

A

1) lunate articular surface
2) Acetabular notch
3- acetabulum labrum (rim of fibrocartilage)- it bridges the notch
4- transverse acetabular ligament
5- hyaline cartilage

240
Q

The joint capsule is a strong fibrous layer that encloses the joint; it is lined by a synovial membrane and has thickened regions that prevent excessive joint movements called INTRINSIC LIGAMENTS. Identify the 3 types of intrinsic ligaments respectively

1- STRONGEST ligament in body, shaped like an inverted Y, attached above the ilium, below to the intertrochanteric line and prevents OVEREXTENSION OF HIP
2- TRIANGULAR ligament attached to superior ramps of pubis and interchocanteric line, limits EXTENSION AND ABDUCTION
3- SPIRAL shaped; attached to ischium and greater trochanter, limits EXTENSION

A

1- ILIOFEMORAL LIGAMENT
2- PUBOFEMORAL LIGAMENT
3- ISCHIOFEMORAL LIGAMENT

241
Q

Name the ligament associated with hip joint

  • inside joint capsule; attached to head of femur at FOVEA CAPITIS and to transverse acetabular ligamnet
  • transmits artery of ligament of head of femur (branch of OBTURATOR artery)
A

LIGAMENT OF HEAD OF FEMUR

242
Q

What is he difference between congenital and traumatizing hip dislocation?

A

CONGENITAL

  • Dislocate SUPERIORLY
  • upper lip of acetabulum may fail to form and head of femur may dislocate superiorly
  • leg is rotated MEDIALLY by action of gluteus medius and minimus which all appear to be shorter

TRAUMATIC

  • dislocate POSTERIORLY
  • rare due to strength of intrinsic ligaments
243
Q

There are 5 main joints in the lower extremity; Knee joint, hip joint, flints between tibia and fibula, ankle joint and joint of inversion and eversion of foot.

Name this joint

  • a condyloid synovial joint between condyles of femur and tibia
  • acts like a hinge type joint which also permits limited rotation
  • has following feature; articular surfaces, capsule, bursae, extracapsular ligaments, intracapsular ligaments and minisci
A

KNEE JOINT

244
Q

Identify the bursa types

1- outpocketing of synovial cavity of knee joint posterior to quadriceps tendon.
2- in subcutaneous tissue between skin ad patella; inflammation is called HOUSEMAID’S KNEE
3- between skin and patella ligament; inflammation is called CLERYGYMAN’S KNEE

A

1- SUPRAPATELLAR BURSA
2- PREPATELLA BURSA
3- SUPERFICIAL INFRAPATELLA BURSA

245
Q

What LIGAMENTS prevents movements of tibia medially and laterally?

A

EXTRACAPSULAR LIGAMENTS

1- lateral collateral ligaments; prevent tibia from moving laterally
2- medial collateral ligaments; prevents tibia from moving medially

** Note: Unlike Lateral Collateral ligament, Medial Collateral ligament is firmly attached to medial meniscus. Both Medial and Lateral Collateral ligaments are taut in extension of knee joint and pull femur against tibia; joint is ‘locked’ when extended.

246
Q

What ligaments prevents movement of tibia anteriorly and POSTERIORLY?

A

INTRACAPSULAR LIGAMENT

1- Anterior cruciate ligament; prevent movement of tibia anteriorly, attached between condyles of tibia,
anterior to intercondylar eminence; passes upward, laterally, and posteriorly to attach to medial side of lateral femoral condyle

2- Posterior cruciate ligament; prevent movement of tibia POSTERIORLY, attached btw condyles of tibia, attachés to lateral side of medial femoral condyle

247
Q

HOW DO YOU TEST FOR TEARS IN THE CRUCIATE ligaments

A

Tear Anterior Cruciate Ligament - can draw tibia anteriorly.

Tear Posterior Cruciate Ligament - can push tibia posteriorly

248
Q

A blow to the lateral side of knee can result in what ?

A

TERRIBLE TRIAD of knee joint

-tear in medial collateral ligament, anterior cruciate ligament and medial meniscus

249
Q

Joints between tibia and fibula have 2 features,

1) broad sheet of connective tissue links shafts of tibia and fibula; has gap for Anterior Tibial artery and vein.
2) ligaments that join bones above ankle joint

A

1- INTEROSSEUS MEMBRANE

2- Inferior articulation
Anterior and Posterior Inferior Tibia-fibula ligaments

250
Q

Name the joint

  • Uniaxial, synovial hinge type joint;
  • permits dorsiflexion and plantar flexion (not inversion or eversion which occurs at joints between tarsal bones).
  • Joint is between talus inferiorly and the tibia and fibula superiorly, capsule surrounds joint
A

ANKLE JOINT

251
Q

IDENTIFY THE FOLLOWING LIGAMENTS OF ANKLE JOINT

1) very STRONG triangular shaped, attaches to medial malleolus of tibia, below to medial surface of talus and calcaneus, permits FREE DORSIFLEXION/PLANTAR FLEXION but limits eversion of foot
2) WEAKER, all attach above to lateral malleolus of fibula, permit FREE DORSIFLEXION/PLANTAR FLEXION but limit inversion of foot

A

1) DELTOID LIGAMENTS

2) LATERAL LIGAMENTS
- anterior and posterior talk Fibula ligaments to talus
- calcaneofibular ligaments to calcaneous

252
Q

1) what causes ankle sprain?

2) what causes POTTS’S fracture

A

1- ANKLE STRAIN

  • caused by EXCESSIVE INVERSION
  • ANTERIOR TALOFIBULAR and CALCANEOFIBULAR ligaments are commonly torn or stretched

2- POTT’S FRACTURE

  • caused by EXCESSIVE EVERSION
  • strong DELTOID LIGAMENT doesn’t rupture but medial malleolus is fractured, also break shaft of fibula
253
Q

Name the following joints of inversion/eversion of the foot

1- between the talus and calcaneous
2- between talus and navicular bones medially, calcaneous and cuboid bones laterally

A

1- SUBTALAR JOINTS

2- TRANSVERSE TARSAL JOINT

254
Q

IDENTIFY the following clinical presentations

1- Distal bone in joint is PARALLEL to midline
2- Distal bone at a joint is deviated LATERALLY away from midline of body
3- Distal bone at a joint is deviated TOWARD midline

A

1- NORMAL
2- GENU VALGUS - knocked knee (normal in infants 3-5)
3- GENU VARUS - bow-legged (normal in infants to age 3)

255
Q

Identify 4 causes of GENU VARUS

A

BOW-LEG

1- blount’s disease (black kids)
2- growth disturbance (epiphyseal dysphasia)
3- Post-trauma
4- Rickets (lack of vitamin D)

256
Q

What are the major inverters of the foot?

Major Everter

What are the antagonist? What is their insertion/

A

1- Major invert foot ; Tibialis anterior and Tibialis posterior

2- major evert foot; peroneus longus, peroneus BREVIS, peroneus tertius

3- ANTAGONISTS- Tibialis anterior and peroneus longus
-they both insert to; medial cuneiform and first metatarsal

257
Q

What are the components of genicular anatomosis

A

1- superior medial genicular artery; anastomosis with descending genicular artery (from femoral artery)
2- superior lateral genicular artery; anastomoses with descending branching of lateral femoral circumflex artery
3- inferior medial genicular artery; anastomoses with recurrent branch of anterior tibial artery
4- Inferior Lateral genicular artery; anastomoses with recurrent branch of anterior tibial artery

258
Q

Name the compartment of leg

Muscle action - Plantar flex foot, Flex toes, Invert foot
Nerve - Tibial nerve
Artery - posterior tibial artery

A

POSTERIOR COMPARTMENT OF LEG

259
Q

NAME the leg compartment

Muscle action - DORSIFLEXION foot, extend toes, invert foot
Nerve - Deep peroneal nerve
Artery - Anterior tibial artery

A

ANTERIOR COMPARTMENT OF LEG

260
Q

Name the leg compartment

Muscle action - evert the foot
Nerve - superficial peroneal nerve
Artery - posterior tibia artery (lateral branch)

A

LATERAL COMPARTMENT OF LEG

261
Q

What is the muscle that usually contain sesamoid bone?

What tendon also contain sesamoid bone?

A

1) LATERAL HEAD of gastrocnemius

2) Flexor hallucis brevis tendon

262
Q

What is the Achilles’ tendon reflex?

A

-tap on tendo calcaneous results in plantar FLEXION of foot

Tests S1 AND S2

263
Q

NAME THE condition and associated symptoms

  • area beneath flexor reticulum, swelling of synovial sheaths
  • can compress tibial nerve
A

TARSAL TUNNEL SYNDROME

-symptoms; numbness of sole of foot, toes and weakened FLEXION of toes (intrinsic muscles of foot)

264
Q

there are 2 components of the lateral compartment of the leg.

Name this
-starts laterally in leg and ends on medial side of foot

A

PERONEUS LONGUS (Major everter)

Origin- fibula
Insertion - medial cuneiform and first metatarsal
Action - evert foot
Nerve - superficial peroneal nerve

265
Q

there are 2 components of the lateral compartment of the leg.

Name this
-starts laterally in leg and ends laterally

A

PERNEOUS BREVIS

Origin - fibula
Insertion - fifth metatarsal
Action - evert foot
Nerve - superficial peroneal nerve

266
Q

1) On the anterior side of leg, what extends from tibia to fibula
2) what is Y-shaped and extends from calcaneous to medial malleolus

A

1 - superior extensor reticulum

2- inferior extensor reticulum

267
Q

There are 5 components of the anterior compartment of leg ; Tibialis anterior, extensor hallucis longus, extensor digitorum longus, peroneus tertius, extensor digitorum brevis

TIBIALIS ANTERIOR

A

MAJOR INVERTER OF Foot and antagonist to peroneus longus

Origin- tibia
Insertion - medial cuneiform and first metatarsal
Action - invert the foot, DORSIFLEX foot
Nerve - deep peroneal nerve

268
Q

There are 5 components of the anterior compartment of leg ; Tibialis anterior, extensor hallucis longus, extensor digitorum longus, peroneus tertius, extensor digitorum brevis

EXTENSOR HALLUCIS LONGUS

A

Origin- fibula and interosseus membrane
Insertion - distal phalanx of big toe
Action - dorsiflex foot, extend big toe
Nerve - deep peroneal nerve

269
Q

There are 5 components of the anterior compartment of leg ; Tibialis anterior, extensor hallucis longus, extensor digitorum longus, peroneus tertius, extensor digitorum brevis

EXTENSOR DIGITORIUM LONGUS

A

Origin - tibia, fibula and interosseus membrane
Insertion - extensor expansions of 4 lateral toes
Action - dorsiflex foot, extend toes
Nerve - deep peroneal nerve

270
Q

There are 5 components of the anterior compartment of leg ; Tibialis anterior, extensor hallucis longus, extensor digitorum longus, peroneus tertius, extensor digitorum brevis

PERONEUS TERTIUS

A

Origin - fibula and interosseus membrane
Insertion - fifth metatarsal
Action - evert foot, dorsiflex foot
Nerve - deep peroneal nerve

271
Q

There are 5 components of the anterior compartment of leg ; Tibialis anterior, extensor hallucis longus, extensor digitorum longus, peroneus tertius, extensor digitorum brevis

EXTENSOR DIGITORIUM BREVIS

A

Origin - calcaneous
Insertion - extensor expansions of toes 2-4
Action - extend toes
Nerve - deep peroneal nerve

272
Q

Name the condition

  • narrowing of posterior tibial artery due to artherosclerosis
  • produces ischemia
  • patients have painful cramps when walking but pain subsides after rest
A

INTERMITTENT CLAUDICATION

273
Q

1) WHERE IS pulse of posterior tibial artery taken?

2) where is pulse of Dorsalis pedis taken?

A

1) Posterior tibial artery taken between medial malleolus and tendo calcaneous
2) Dorsalis pedis pulse taken on dorsum of the foot between medial and lateral malleolus

274
Q

Anterior tibial artery passes through interosseus membrane to anterior compartment, it descends with deep peroneal nerve. Name the branches;

1) part of anastomosis of knee
2- form anastomosis of ankle
3- continuation of anterior tibial artery
4- branch of Dorsalis pedis, gives rise to dorsal digital arteries to toes

A

1- Anterior tibial recurrent artery
2- lateral and medial malleolar arteries
3- Dorsal is pedis
4- arcuate artery

275
Q

What parts of foot function like springs that store energy in walking (important in design of prosthetic?

A

LIGAMENTS AND ARCHES OF FOOT

276
Q

What is ;

  • thickened, tough band of deep fascia on sole of foot,
  • extends from calcaneous and distally divides into connective tissue bands for all five toes
  • protects underlying structures and helps support arch (lateral longitudinal arch) of foot
A

PLANTAR APONEUROSIS

277
Q

What is ;

  • thickened bands attached to side of phalanges
  • form tunnels for passages of long tendons to toes and prevents bowstringing (tendons popping out when muscles contract)
A

FIBROUS DIGITAL SHEATHS

278
Q

There are 4 layers of the muscles of the foot

What comprises of the first layer? Actions and nerves

A

1- Flexor DIGITORIUM brevis
action - flex lateral four toes
Nerve - medial plantar nerve

2- Abductor hallucis
Action - abduct and flex big toe
Nerve- medial plantar nerve

3- Abductor digiti minimi
Action - abduct and flex little toe
Nerve - lateral plantar nerve

279
Q

There are 4 layers of the muscles of the foot

What comprises of the second layer? Actions and nerves

A

1) Lumbricals
Action - flex toes at metatarsophalangeal joint and extend toes at interphalangeal joint
Nerve - lumbrical 1 is medial plantar nerve
Lumbicals 2-4 is lateral plantar nerve

2) quadratus Plantar
Action - assist in flexing lateral four toes
Nerve - lateral plantar nerve

280
Q

There are 4 layers of the muscles of the foot

What comprises of the third layer? Actions and nerves

A

1- Flexor hallucis brevis (has sesamoid bones)
Action - flex big toe
Nerve - medial plantar nerve

2- flexor digiti minimi brevis
Action - flex little toe
Nerve - lateral plantar nerve

3- adductor hallucis
Action - ADDUCT and flex big toe
Nerve- lateral plantar nerve

281
Q

There are 4 layers of the muscles of the foot

What comprises of the fourth layer? Actions and nerves

A

1- Plantar interosseous muscles (PAD)
Action - ADDUCT toes and flex metatarsophalangeal joint
Nerve - lateral plantar nerve

2- Dorsal interosseous muscles (DAB)
Action - abduct toes and flex metatarsophalangeal joint
Nerve - lateral plantar nerve

282
Q

1 - Posterior tibial artery divides into what?

A

Divides into medial and lateral plantar arteries

1) Lateral plantar artery - gives rise to plantar arterial arch, located deep in foot, plantar arch gives rise to plantar metatarsal arteries which branch to sides of toes as plantar digital arteries
2) medial plantar artery - smaller branch to medial foot

283
Q

Tibial nerve divides into what

A

Divides into lateral and medial plantar nerves

1) medial plantar nerve
- sensory branches 3.5 digits and medial part of sole
- motor branches muscles of BIG TOE (flexor hallucis brevis, abductor hallucis, Flexor DIGITORIUM brevis, first lumbrical)

2- lateral plantar nerve ;

  • sensory branches to lateral 1.5 digits and lateral sole
  • motor branches to remaining intrinsic muscles of sole of foot
284
Q

There are 3 arches of the foot

WHich is this

  • HIGHEST arch, responsible for ‘fallen arches’
  • formed by- calcaneous, talus, navicular, cuneiform and medial 3 metatarsal bones, talus is highest point of arch
  • supported by ligaments and muscles
A

MEDIAL LONGITUDINAL ARCH

1- plantar CALCANEONAVICULAR LIGAMENT - spring ligament, most important ligament that keeps head of talus high off ground (stretch this ligament will result in flat feet)
2- Tibialis posterior and Tibialis anterior - insert to medial side of foot and support arch

285
Q

There are 3 arches of the foot

WHich is this
a. formed by - calcaneus, cuboid and lateral two metatarsals;
cuboid is highest point of arch.
B. Supported by long plantar ligament and plantar aponeurosis, peroneal tendons

A

LATERAL LOGITUDINAL ARCH

-smaller than medial

286
Q

There are 3 arches of the foot
Which is
-formed by cuneiform and cuboid bones and metatarsals
-supported by interosseus muscles and peroneus longus tendon

A

TRANSVERSE ARCH