Exam 3 Flashcards
Which mycobacterium has a very broad host range, including badgers and brush tail possums?
Mycobacterium bovis
What is the reservoir for Mycobacterium leprae?
armadillo
What is the main host for Mycobacterium lepramurium?
cats
Which mycobacterium is dependent on Mycobactin for growth?
M paratuberculosis
What organism causes Johne’s disease?
M avium susp. paratuberculosis
What can cause a false negative on ELISA when testing for Johne’s disease in the late stages?
anergy
Are mycobacteria gram positive or negative?
gram + (and acid fast +)
Are spirochetes gram negative or positive?
gram -
Which spirochete causes swine dysentery?
Bradyspira hyodysenteriae
T/F B pilosicoli has a synergistic relationship with other anaerobes in the colon.
T
Which organism causes lesions only in the large intestine, creating a sharp demarcation at the ileocecal junction?
Bradyspira
Which organism causes rabbit syphilis?
Treponema paraluis (caniculi)
Papillomatous digital dermatitis is caused by which organism?
Treponema
Other names for papillomatous digital dermatitis (PDD)?
hairy heel warts, strawberry foot disease
Treatments for strawberry foot disease?
spray feet with antibiotic, formaldehyde foot baths
*caution carcinogens
Borrelia burgdorferi causes what?
lyme disease
What organism causes avian borreliosis?
B anserina
outer surface proteins in B. burgdorferi
C -> A in midgut of tick
A -> C in salivary glands of tick
C in mammals in early infection
Which ticks transmit B. burgdorferi?
ixodes scapularis (east US) and ixodes pacificus (west US)
How do you interpret a lyme test?
clinical signs but negative test = retest
no clinical signs but positive test = subclinical
*only treat in endemic areas
Do you always treat for Borrelia burgdorferi?
No, most infections are subclinical
Can give dogs doxy in endemic areas
*vaccine decreases incidence
How would an animal acquire a Leptospira infection?
direct contact with infected urine or water
What is a concern with a leptospira infection in a dog?
chronic kidney disease
To diagnose a leptospira infection in early stages (week 1-2), what should you PCR?
blood
To diagnose a leptospira infection in later stages (week 3-4) what should you PCR?
urine
What type of immunity is most important for a lepto infection?
humoral
Which organism could cause blood tinged milk in a cow?
L. pomona
What does L. borgpetersonni cause in cattle?
reproductive failure due to embryonic death and repeat breeding
*vaccine
How should you collect urine to diagnose Leptospira?
catch urine midstream and give Lasix
Which lepto organisms infect horses?
L. pomona and L. grypptyphosa
T/F Rickettsiales are facultative intracellular and gram +
F: obligate intracellular and gram -
Which organisms are in the family Anaplasmataceae?
anaplasma
ehrlichia
neorickettsia
What cells does anaplasma infect?
myeloid cells, neutrophils, RBC
T/F Anaplasma marginale is reportable.
T
Which tick transmits A. marginale?
Boophilus microplus
Which organism causes undulating febrile disease?
A. marginale
Which cells does A. phagocytophilum infect?
neutrophils and eosinophils
Clinical signs of A. phagocytophilum?
fever (not undulating), leukopenia, splenomegaly
Which cells does A. platys infect?
platelets
What organism causes infectious canine thrombocytopenia?
A. platys
T/F Rickettsiae are motile
F
What causes RMSF?
Rickettsia Rickettsii
What is the first clinical sign for RMSF?
vasculitis (infect endothelial cells)
What can cause RMSF to be fatal in dogs?
severe necrosis in extremities
Are there vaccines for rickettsia?
nope
What is the common name for Coxiella burnetti?
Q fever
Is C burnetti reportable?
yes, bioweapon
What is the main host of C burnetti?
sheep
What is important to remember when treating Q fever?
need an alkalinizing agent to kill in the phagosome
*chloraquine + tetracycline
T/F you can’t distinguish C. psitticai and C. burnetti clinically?
T
Which cells does Ehrlichia canis infect?
WBC; obligate intracellular
What causes canine monocytic ehrlichiosis?
E. canis
What does E. chaffeensis cause?
human monocytic ehrlichiosis
What does E. ewingii cause?
canine granylocytic ehrliciosis
What causes African heartwater?
E. ruminatum
Clinical signs of african heartwater?
capillary damage -> edema
damage to cerebrocortical capillaries = neuro signs
fever
Important diseases of Neorickettsia:
Salmon poisoning : N salmincola
Potomac Horse Fever
Do mollicutes have a cell wall?
no