exam #3 Flashcards

1
Q

iatrogenic addiction

A
  • addiction inadvertently caused from valid medical use of opioids
  • actual incidence is 1%
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2
Q

addiction

A
  • primary, chornic, neurobiological disease with genetic, psychosocial, and environmental factors influencing its development and manifestation
  • behaviors include: impaired control over drug use, compulsive use, continued use despite harm, and craving
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3
Q

physical dependence

A
  • state of adaptation that is manifested by a drug class specific withfrawal syndrome following: abrupt cessation, rapid dose reduction, decreasing blood levels, and/or administration of an antagonist
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4
Q

tolerance

A
  • state of adaptation in which exposure to a drug induces changes that result in diminution of one or more of the drug’s effects over time
  • use of words: drug seeker, clock watcher, addicted to their pain meds
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5
Q

pain transmission

A

1) tansduction
2) transmission
3) perception
4) modulation

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6
Q

categories of pain

A
  • acute: traumatic injury, surgical procedure, medical disorder
  • chornic: lasting more than 6 months
  • nociceptive pain: complex interaction between peripheral nerves and central nervous system
  • somatic: soft tissue, musculoskeletal
  • visceral: abnormal stretching, distention of smooth muscles
  • neuropathic pain: disruption to nerves
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7
Q

non-opioid, adjuvant, co-analgesic agents

A
  • NSAIDs
  • cox-2s
  • tricyclic antidepressants
  • anticonvulsants
  • alpha 2 adrenergic agonists
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8
Q

opioids

A
  • endogenous opioids
  • opioid receptors
  • agonist-antagonist
  • antagonist
  • parenteral: continuous IV, intermittent doses, combination
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9
Q

nursing points of care opioid medications

A
  • kept under double lock
  • record use
  • lost or contaminated doses must be signed for
  • counted by 2 nurses and signed
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10
Q

PCAs

A
  • patient controlled analgesics
  • anticipating pain that is severe but intermittent
  • constant pain that gets worse with activity
  • not already sedated from other medications
  • SQ administration
  • provides serum analgesia levels for comfort with minimal sedation
  • good candidates: kidney stones, constant pain that worsens with activity, capable of manipulating the dose button, motivated to use PCA, home care pts with long term pain control needs
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11
Q

advantages and disadvantages of PCAs

A
  • advantages: acute pain relief, good for post op pts, safe and effective, constant therapeutic serum level, abdominal surgery pts end up ambulating sooner, better able to cough and deep breath when pain is controlled
  • disadvantages: risk for respiration supression, LOC must be in tact to manage pain, constipation, nausea, vomiting, pruritis
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12
Q

points of care with PCAs

A
  • must determine pt baselines first
  • must determine first bolus, lock out interval between each dose, and the 1 hours and 4 hours lock out dose limits
  • always validate with another caregiver
  • current guidlines: 6-8 minute dose interval and 1 hour lockout
  • ONLY pt can touch it
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13
Q

SQ infusions

A
  • provides hydration into SQ tissues
  • candidates for continuous SQ: unable to take PO, moderaltely dehydrated and confused, pts with limited venous access
  • advantages: ease of initiation and maintenance, reduction in transfers to acute care from long term care for IV therapy, fewer complications, decreased cost
  • disadvantages: local irritation at infusion site, inappropriate for large volumes, edema, risk of infection, risk of abscess formation
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14
Q

points of care: SQ infusions

A
  • rotate site q 3-5 days, monitor access site
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15
Q

pain mngmt epidural and intrathecal medication

A
  • spinal cord and brain
  • decreases risk for thrombophlebitis and paralytic ileus
  • common epideral meds: preservative-free morphine, sublimaze (fentanyl), sufentanil, bupivacaine, lidocaine, tetracaine
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16
Q

JCAHO guidelines for pain assessment

A
  • pt right to appropriate assessment and mngmt of care
  • assess pain in all pts
  • record the results in a way that facilitates regular assessment and follow up
  • educate relevant providers in pain assessment and mngmt
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17
Q

neonate

A
  • extra uterine life up to the first 28 days
  • low birth weight and premature infants have decreased energy stores and increased metabolic needs compared with those of full term and average weight newborns
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18
Q

water

A
  • premi: 90% water
  • newborn infant: 70-80% water
  • adult: 60%
  • infants have more water in the extracellular compartmant than adults do
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19
Q

ped IV therapy

A
  • illness, increased muscular activity, thermal stress, congenital abnormalities and resp distress syndrome influence metabolic demands
  • metabolic demand of an infant is 2Xhigher per unit of weight than that of an adult
  • for high-risk infants, calorie requirement is up to 100% higher than normal newborn
  • renal fxn, acid base balance, body surface area, and electrolyte concentrations must be taken into consideration when planning fluid needs
  • renal fxn is not completely developed, kidneys have limited concentrating ability and require more water to excrete a given amount of solutes
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20
Q

candidates for neonatal and infant IV fluids

A
  • neonatal: congenital cardiac disorders, GI defects, neurologic defects
  • infant: dehydration, diarrhea, abx therapy, nutritional support, antineoplastic therapy
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21
Q

pediatric physical assessment

A
  • measurement of the head circumference (up to 1 year)
  • height or length
  • weight
  • vital signs
  • skin turgor
  • presence of tears
  • mucous membranes
  • urinary output
  • fontanelles
  • level of activity
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22
Q

peds assessment of fluid needs

A
  • meter square method (body surface area): nomogram used
  • weight method: 100-150ml/kg to estimate fluid requirements
  • caloric method: calculates the usual metabolic expenditue of fluid
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23
Q

IV site selection in peds

A
  • age, size, condition of vein, reason for therapy, general pt condition, mobility, level of activity, gross and fine motor skills, sense of body image, fear of mutilation, cognitive ability of the child
  • sites: subclavian, cephalic, brachial, temporal, posterior auricular, jugular, basilic
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24
Q

geriatric iv therapy

A
  • loss of cells and loss of physiologic reserve make up the dominant processes of aging
  • major changes: homeostatic changes, immune system, cardio changes, skin and connective tissue changes
  • less fluid
  • less ability to adapt readily to rapid changes
  • renal changes: decreased GFR
  • total body water reduced by 6%
  • cardio and resp changes combine to contribute to a slower response time to blood loss, fluid depletion, shock, acid base imbalances
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25
Q

assessment guidelines for geriatric patients

A
  • skin turgor forehead or sternum
  • tempareate
  • rate and filling of veins in hand or foot
  • daily weight
  • I&Os
  • tongue
  • orthostatic
  • swalloing ability
  • fxnl assessment
26
Q

tips for fragile veins in elderly

A
  • to prevent hematoma, avoid overextension
  • avoid multiple tapping of the vein
  • use the smallest gauge needle necessary
  • lower the angle of approach
  • pull the skin taut and stabalize the vein
  • one handed technique
27
Q

basic immunohematology

A
  • science that deals with antigens of the blood and their antibodies
  • genetically inherited
  • antigens of RBCs = A, B, AB, and the absence of antigens, O
  • RH system: 2nd most important RBC antigen is the D antigen; D, C, E,c, e; presence of D antigen = Rh positive, ; absence of D antigen = Rh negative
  • HLA antigen: present on most cells in the body, important in pts with transplants or multiple transfusions and paternity typing; possible cause of hemolytic transufison reactions
28
Q

blood donor testing

A
  • ABO group and Rh type
  • specific screening tests: hep B surface antigen (HBxHg), hep B core antibody (anti-HBc), hep C virus antibody (anti-HCv), HIV-1 and HIV-2 antibody, serology for syphillis, west nile virus
  • blood bank has two objectives: prevent antigen-antibody reactions in the body, identify antibody that the recipient may have and to supply blood that lacks the corresponding antigen
29
Q

blood donor collections method

A
  • homologous: someone other than the recipient
  • autologous: pt own blood (no age limit, underweight pts exclused, drawn a week prior to need)
  • types: predeposit or peroperative (autologous), acute normovolemic hemodilution (donate to reduce hematocrit), intraoperative blood salvage (give back if needed), designated (donate to specific people)
30
Q

storage of blood

A
  • food source must be provided to maintain adequate nutrtion to the stored cells
  • anticoagulation must be acheived to ensure that the blood remains in its liquid cellular state for the duration of the storage period
  • citrate nutrition with anticoags
31
Q

items that can be used in blood

A
  • RBCs
  • granulocytes
  • plasma
32
Q

whole blood

A
  • RBCs, plasma, WBCs, platelets

- 500ml, 200ml, RBCs, 300ml plasma

33
Q

RBCs

A
  • packed RBC volume of approx 300ml
  • advantages: decreased plasma volume, decreased risk of circulatory overload, less citrate/potassium/ammonia/other metabolic by products are transfused
  • leukocyte-reduced red blood cells:
  • modified blood products
  • filtered with a special filter
  • prevention of febrile, nonhemolytic transfusion reactions
  • deglycocerolized red blood cells:
  • allows for freezing for long term storage
  • rare units
  • autologus donor units
34
Q

irradiated blood products

A
  • donor lymphocytes become incapable of replication
  • prevention of graft vs. host disease
  • acute leukemia and lymphoma
  • bone marrow or stem cell transplant
  • immunodeficiency disorders
  • neonates and low birth weight infants
35
Q

granulocytes

A
  • replaced by neupogen (helps body make WBCs)
36
Q

platelets

A
  • random-donor concentrates or single-donor concentrates
37
Q

plasma and fresh frozen plasma

A
  • liquid used to replace plasma proteins lost from injury

- FFPlasma provide replacement coagulation factors

38
Q

cryoprecipitate

A
  • hypofibrinogenemia: massive transfusion, congenital deficiency, acquired deficiency (DIC)
  • factor VIII deficiency
  • uremia with bleeding
  • dysfunctional fibrinogen
39
Q

albumin

A
  • plasma protein supplies 80% of plasma’s osmotic activity
40
Q

administration of blood components

A
  • always check with 2 RNs
  • use 18gauge when you can
  • run blood with normal saline
  • consent like a transplant
  • saline can be mixed with blood to thin it out
  • run blood wide open and then slow it down over time
  • check VS q mins then q15 then q 30 for 12 hours
  • benadryl, solumedrol and tylenol given for reactions
  • never give 2 units of blood at same time, different sites
  1. verify physician’s orders
  2. blood typing and crossmatching the recipient
  3. selecting and preparing the equipment (catheters, solution, admin set, special filters, fluid/blood warmers)
  4. prepare pt
  5. obtain blood product from blood bank
  6. prepare for admin
  7. initatie transfusion
  8. monitor transfusion
  9. discontinue the transfusion
41
Q

complications of blood admin

A
  • acute hemolytic rxn: result of clerical error, incorrect labeling, not identifying the rt pt
  • delayed hemolytic rxn
  • nonhemolytic febrile rxn
  • allergic rxn
  • alloimmunization and regractoriness (antibodies develop to blood after several infusions)
  • graft vs host disease
  • non immune rxns: circulatory overload, potassium toxicity, hypothermia, citrate toxicity, bacterial contamination
42
Q

pall blood filter

A

filter

43
Q

transfusion transmitted diseases

A
  • hepatitis
  • CMV
  • HIV
  • West Nile
  • Creutzfeldt jakob disease, mad cow disease
  • severe acute resp syndrome
  • smallpox
  • parasitic infections
44
Q

phlebotomy technique

A
  1. preparation of healthcare worker
  2. assessing the pt physical disposition
  3. identifying pt
  4. approach pt
  5. selecting puncture site
  6. selecting and preparing equipment and supplies
  7. prepare site
  8. chose venipuncture method
  9. colleting the samples in the appriparite tubes and in the correct order
  10. labeling samples
  11. assess the pt after withdrawl of the blood specimen
  12. considering any special circumstance that occured during the phelbotomy procedures
  13. assess criteria for sample recollection or rejection
  14. prioritizing patients and sample tubes
45
Q

test requisitions

A
  • pt full name
  • pt ID or medical number
  • pt dob
  • types of test to be performed
  • date of test
  • room number and bed
  • physician’s name and or code
46
Q

tube guide

A
  • purple: CBC
  • red: cell separator, clots, drug levels
  • blue: PT INR
47
Q

nutritional support

A
  • care of individuals with potential or known nutritional alterations
  • parenteral nutrition may be a factor in supporting and sstaing life
  • the dilemma of withholding versus withdrawing therapy has been a topic of much debate and many publications
  • goals: provide all essential nutrients when oral or parenteral routes arent sufficient; preserve or restore the body’s protein metabolism and prevent development of protein or caloric malnutrition; diminish rate of weight loss; promote wound healing; replace nutritional deficits
48
Q

concepts of nutrition

A
  • nutritional balance depends on 3 things: intake of nutrients, relative need for nutrients, ability of the body to use nutrients
  • nutrients are required for the provision of energy, growth and support of tissues, and regulation of physioloiigcal processess within the body
  • malnutrition: present when an imbalance occurs between nutrient intake and requirements
  • three types of malnutrition:
  • marasmus: decease in intake of calories with adequate protein calrieu ratio, gradual wasing = anorexics
  • kwashiorkor: adequate intake of calories along with a poor protien intake, 3rd world hunger, big bellies
  • mixed malnutrition: hospital patients, both aspects of malnutrition
49
Q

effects of malnutrition

A
  • loss of muscle mass
  • impaired wound healing
  • impaired immunologic fxn
  • decreased appetite (when in a state of starvation)
  • loss of calcium and phosphate from bone
  • anovulation and amenorrhea in women
  • decreased testicular function in men
50
Q

specific disease states

A
  • gastrointestinal: cant absorb properly
  • cardiac: energy all goes to heart and impedes digestion
  • pulmonary
  • liver: injured organs can heal if put on TPN
  • pancreatitis
  • short bowel syndrome (bowel removed, on TPN for life)
  • renal failure
  • cancer
  • cirtical illness - ICU intubation
  • AIDS
51
Q

nutritional assessment

A
  • anthropometric measurements: mild malnutrition 85-95% IBW, moderate 75-84% IBW, severe less than 75%
  • biochemical assessment: serum albumin and transferrin levels, prealbumin and retinol-binding protein, total lymphocyte count, serum electrolytes
  • energy requirements: BSA, age, genter
  • physical exam
  • nitrogen balance
  • prognostic nutritional index (related risk of morbidity to nutritional status)
52
Q

nutritional requirements

A
  • carbs: provide energy, 10-20% glucose
  • protein: body building nutrient promotes tissue growth and repair and replacement of body cells
  • TPN: hypertonic solution, given via CVA device
  • fats: primary source of heat and energy
  • electrolytes: indused as a component already contained in the amino acid solution or as an additive
  • vitamins: necessary for growth and maintenance, multiple metabolic processes
  • trace elements: basic requirements are very small but essential
53
Q

parenteral nutrition medication additives

A
  • insulin
  • heparin
  • histamine 2 inhibitors (GERD, GI issues)
54
Q

considerations for parenteral nutrition

A
  • patient unable to ingest sufficient nutrietns through Gi tract
  • the least invasive, lease expensive nutritional support should be considered
  • Gi route should always be used if appropriate
  • goal is for pt to gain 1/2 lb per week
  • turn off TPN 3-5 mins before drawing blood
  • general rule: when 5-7 days have passed with insufficient enteral intake, parenteral nutrition should be considered
55
Q

admixture complications

A
  1. amts of calcium and phosphorus added
  2. phosphate ions
  3. line should be flushed: incompatible components
  4. lipid emulsion: obscure presence of precipitates
  5. filter used for administration 1.2 micron
  6. administered within 24 hours after mixing or removal from refrigerator
  7. symptoms of acute resp distress, pulmonary emobolus or interstitial pneumonitis develop stop immediately
56
Q

antineoplastic therapy, chemotherapy

A
  • goal: curative, palliative
  • nurse responsibility: knowledge of disease process, drug classifications, pharmacologic indications, actions, side effects, adverse rxns, method of admin, rate of delivery, tx, goal, drug properties
57
Q

giving antineoplastic therapy

A
  1. smaller the tumor burden the easier the patient is to tx
  2. surgical debulking decreases the tumor burden and recruits malignant cells to start dividing, therby increasing the sensitivity to chemo
  3. higher the dose, the better the chance for response
  4. doses are altered basedo n the degree of toxicity the pt experiences
  5. therapuetic margin is the diff between the dose producing the desired benefit and the dose resulting in unacceptable toxicity
  6. theraputic margin is narrow compared with that of other types of drug
58
Q

antineoplastic agents

A
  • classifications: classified according to the cell life cycle, specific and non specific to cell cycles
  • combination chemo: drugs given in specific combinations to work at diff phases of the cell cycle
  • reductive therapy: debulking, decreases the body burden of cancer cells
  • adjuvant chemo: admin of chemo to destroy micrometastasis and to prevent secondary tumors
  • intermittent therapy: intermittent high dose therapy with CCS and CCNs agents gives better therpeutic results with fever toxic side ffects than more frequent divided doses. yields better cell kill
59
Q

shrot term complications of antineoplastic therapies

A
  • venous fragility
  • alopecia
  • diarrhea
  • constipation
  • altered nurtitional status
  • anorexia and alteration in taste
  • fatigue
60
Q

acute rxns from chemo

A
  • hypersensitivity, anaphylaxis
  • extravasation
  • stomatitis
  • mucositis
  • n/v
  • myelopsupression
  • neutropenia
  • thombocytipenia
  • anemia
61
Q

toxicities from chemo

A
  • neurotoxicity: vinonstine
  • cardiac toxicity: adreomycin
  • pulmonary toxicity: bliomyocin
  • renal toxicity: processed in kidneys
62
Q

chemo routes of admin

A
  • iv
  • intrathecal
  • regional
  • intraarterial
  • intraperitoneal
  • cerebrospinal fluid resevroirs
  • infusion pumps