Exam 3 Flashcards
Obstructive Lung Diseases (3)
- Asthma
- Chronic Bronchitis
- COPD (emphysema)
Characterisitics of COPD
- chronic airway obstruction
- airflow limitation
- generally progressive over time
- may have airway hyperactivity (reversible component)
define Emphysema
a pathologic diagnosis based on a permanent abnormal dilation and destruction of the alveolar ducts and air spaces distal to the terminal bronchioles
define Chronic Bronchitis
a clinical diagnosis based on the presence of a cough and sputum production occurring on most days for at least a 3-month period during 2 consecutive years without another explanation. Cough is not necessarily accompanied by airflow limitation.
Identify this condition and describe the management:
cc: shortness of breath while exercising
exam: pt is thin, breathing through pursed lips and using accessory muscles, and has no cough or sputum production
x-ray:
Emphysema - Pink Puffer
managment:
- stop smoking
- inhaled beta-2 agonists (Albuterol); anticholinergic (Ipratropium)
- inhaled/oral corticosteroids
- theophylline
- oxygen therapy (end-stage)
- antibiotics
- influenza and pneumococcal vaccines
on x-ray note: hyperinflation, hyperlucency, increased retrosternal air space, flat diaphragm, small heart, bullae formation
pt will also have decreased P02 and normal or decreased PCO2
Identify this condition and describe the management:
cc: coughing up phlegm and shortness of breath while exercising and just sitting at home
exam: you note the pt is obese
x-ray:
Chronic Bronchitis (ain’t no body got time for that) - Blue Bloater
managment:
- stop smoking
- inhaled beta-2 agonists (Albuterol); anticholinergic (Ipratropium)
- inhaled/oral corticosteroids
- theophylline
- oxygen therapy (end-stage)
- antibiotics
- influenza and pneumococcal vaccines
x-ray findings: normal or incrased lung markings, cardiomegaly, pulmonary HTN, cor pulmonale
pt will have reduced PO2 and elevated PCO2
Identify this condition:
pt is a 25 year old non smoker complaining of shortness of breath on exertion
CXR shows a panacinar distribution of emphysema
Alpha-1-antitrypsin deficiency
management: replace alpha-1-antitrypsin, eliminate exacerbating factors, COPD management (fpnotebook.com)
Stage 1 Mild COPD
FEV1/FVC < 70%
FEV1 > 80% predicted
with or without chronic symptoms
Stage 2 Moderate COPD
FEV1/FVC < 70%
30 < FEV1
with or without chronic symptoms
Stage 3 Severe COPD
FEV1/FVC < 70%
FEV1 < 30% predicted or < 50% predicted plus respiratory failure or clinical signs of right heart failure
Identify this condition and describe the managment:
pt: reports shortness of breath on exertion, chronic wet cough
exam: little or no sputum production, elevated jugular venous pressure and hepatomegaly
CXR: enlarged RV and PA
Cor Pulmonale
RV hypertrophy and eventual failure
results from pulmonary disease: hypoxia, pulmonary vascular disease, COPD
diagnosis:
ECHO excludes LV dysfunction
ECG changes: RVH, tall peaked P waves, right axis deviation
Chantix (varenicline)
targets the same receptors as nicotine and blocks nicotine from binding
helps reduce the urge to smoke
Clinical Strategies for Smoking Cessation (5 A’s)
ASK - identify smokers at each visit
ADVISE - urge smokers to quit
ASSESS - readiness to make an attempt to quit
ASSIST - counseling and meds
ARRANGE - schedule follow-up contact
Asthma Symptoms
- Cough - with or without expectoration of excessive mucus
- Hemoptysis - part of Churg-Strauss vasculitis or allergic bronchopulmonary aspergillosis
- Shortness of breath
- Wheeze
- Chest tightness or pain
- Hyperventilation Syndrome
Asthma Control: Medications
follow-up every 1-6 months to make sure control is being maintained - use the lowest effective dose
Long-term control - medication taken daily to achieve and maintain control
- corticosteroids
- cromolyn sodium and nedocromil
- long acting beta-2-agonists
- leukotriene modulators
Quick-relief - medications taken to provide prompt relief
- short acting beta-2-agonists
- anticholinergics
- systemic corticosteroids
Complementary Alternative Medicine
- epinephrine
- ephedra
Asthma Exam Findings
- wheezing (cannot be used as a predictor of severity of airflow obstruction)
- use of accessory muscles of breathing - inspiration
- eczema, atopic dermatitis or other types of allergic skin disorders
Asthma History
- history of intermittent, seasonal waxing/waning of symptoms
- noctural episodes
- exacerbation of symptoms on exposure to:
- exercise
- excitement
- stress
- cold air
- aeroallergens (pollen, mold, animal dander)
- URI
- strong odors
Pathophysiology of Asthma
smooth muscle dysfunction
airway inflmmation
airway remodeling
Differential Diagnosis of Cough - Adults
- COPD
- Heart Failure
- PE
- Laryngeal dysfunction
- Tumor
- Pulmonary infiltration with eosinophilia
- Secondary to drugs
- Vocal cord dysfunction
- GERD
Differential Diagnosis of Cough - Children
- allergic, rhinitis and sinusitis
- foreign body in trachea or bronchus
- vocal cord dysfunction
- vascular rings or laryngeal webs
- enlarged lymph nodes or tumor
- cystic fibrosis
- heart disease
- GERD
Asthma Control Components (4)
- assessment and monitoring
- education for parternship in care
- control of environmental factors and comorbid conditions
- medications
Diagnosis of Asthma
Spirometry
FEV1 is the most important variable - declines in direct/linear proportion with obstruction; increases after successful treatment
FEV1/FVC ratio > 75 is normal
Histamine/methacholine challenge - increase dose until FEV drops 20%
Short acting bronchodilator - increase FEV >12% of 200 mL - significant reversibility
Definition of Asthma
chronic inflammation disorder
airflow obstruction
severe narrowing of the airways
wheezing, coughing, breathlessness, chest tightness
reversible
recurrent episodes
Risk Factors of Death from Asthma
- past hx of sudden severe exacerbations
- prior intubations for asthma
- admission to ICU for asthma
- 2+ hospitalizations for asthma
- 3+ ER visits for asthma
- low socioeconomic status
- >2 canisters/month of inhaled short acting beta-agonist
- current use of systemic corticosteroids
- difficulty perceiving airflow obstruction
- illicit drug use