Exam 3

Question 1

Cystic Fibrosis Class 1

Answer 1

No functional CFTR is made

Question 2

Cystic Fibrosis Class 2

Answer 2

CFTR is made but is folded incorrectly, causing the protein to not localize to the right place.

Question 3

Cystic Fibrosis Class 3

Answer 3

CFTR is made and successfully localized, but it does not open

Question 4

Cystic Fibrosis Class 4

Answer 4

CFTR is made and successfully localized, but the function is not sufficient

Question 5

Cystic Fibrosis Class 5

Answer 5

CFTR is made and successfully localized, but it is not made in sufficient amounts

Question 6

Ivacaftor, tezacaftor, and elexacaftor use

Answer 6

Helps localize CFTR and allow it to open

Question 7

cAMP function

Answer 7

Secondary messenger molecule that amplifies signals and activates PKA. There are tons in the cell that work together to amplify signals

Question 8

PKA function

Answer 8

Activates phosphorylase kinase via phosphorylatioin

Question 9

Which cells have glucagon receptors?

Answer 9

Liver cells, because they help break down glycogen to release glucose into the bloodstream