Exam 3 Flashcards
Hepatic artery
Brings blood into the liver for filtration
Where does filtered blood go after liver
Returns to right heart through hepatic vein
Portal vein
Brings nutrient-rich blood from GI to liver
Hepatocytes
Liver cells that perform liver functions
Causes of impaired liver function
Cirrhosis
Portal hypertention
Hepatitis, liver infections
Wilson’s disease
Autoimmune disorders -
Liver cancer
Fatty liver disease (nonalcoholic fatty liver or nonalcoholic steatohepatitis)
Risk factors for liver disease
ETOH use
Multiple medication use
Foreign travel
Hepatitis risk
Liver function dx
Abdominal xray - liver enlargement
Cholangiogram - picture of bile ducts
Liver scan - IV contrast detects liver cycts/masses
Liver biopsy - evaluates damage and extent of liver cancer
Manifestations of liver dysfunction
Jaundice
Portal hypertension
Ascites
Hepatic encephalopathy
Nutritional deficits
What is produced from liver impairment
Ammonia
Complications of liver disorders
Portal hypertension
Esophageal varices
Fluid volume overload - ascites
Hepatic encephalopathy
Portal hypertension patho
Portal vein narrows d/t scar tissue
Restricts blood flow to liver
What does an enlarged spleen (splenomegaly) causes
Decreased platelets and WBC’s
Impaired liver s/sx
Fatigue
Increased peripheral venous pressure
Ascites
Enlarged liver and spleen
JVD
Anorexia, GI distress
Weight gain, dependent edema
How to dx ascites
Fluid wave test
Shifting dullness in abdomen
Striae or blood vessel engorgement in abdomen
What can ascites lead to
Hypokalemia
Dehydration
Spontaneous peritonitis
Management of ascities
Low sodium diet
Diuretics
Bed rest
Paracentesis - remove fluid
TIPS (transjugular intrahepatic portosystemic shunt) or peritoneovenous shunt (PVS)
Second line therapy for ascites/varices if diet/fluid modifications are ineffective
Bypass injured liver to decrease fluid retention
Improves fluid and sodium retention
Improves diuretic response
Ascites nursing management
Abd girth, daily wts
Monitor for fluid and electrolyte imbalances - respiratory complications
Sodium restriction - 2g/day
Diuretics - spironolactone
Bed rest, raise HOB
Surgery - shunt
Hepatic encephalopathy patho
Unable to detoxify ammonia and other toxins in the brain
Hepatic encephalopathy risk factors
Cerebral depressants (opioids)
Constipation
Dehydration
Hypokalemia
Infection
Paracentesis
TIPS