Exam 3 Flashcards
Which is NOT a property of the keystone pathogen for periodontitis?
> C: becomes the main species present in disease sites
Which bacterium is considered the keystone pathogen for periodontitis?
> E: Porphyromonas gingivalis
Which disease has oral manifestations that include gummas?
> A: syphilis
Which Streptococcal virulence factor is correlated with the progression of infective endocarditis?
PAAF
5 Which of the following is characteristic of Ludwig’s angina?
> D: infection is polymicrobial (multiple species)
6 How do mucins act as antibacterial agents? 1/1
> E: mucins aggregate and clear oral bacteria via lectin-like interactions
8 Aggregatibacter actinomycetemcomitans is very typically associated with which oral disease? 1/1
> D: aggressive periodontitis
What is one of the types of oral bacteria strongly associated with acute necrotizing ulceratize gingivitis? Answer:
Answer 1: Fusobacterium nucleatum
What is a property characteristic of cariogenic bacteria (versus noncariogenic bacteria)?
> C: presence of acid stress response proteins
Name a bacterium that is a common late colonizer of dental plaque when oxygen is depleted, especially between teeth?
Prevotella
What is true of dental plaque?
Sugar consumption causes increased levels of streptococcus mutans in plaque
What bacterial gene is used in current methods for classifying bacteria, including identifying new species?
16s RNA
Which property of bacteria in a dental biofilm is associated with decreasing the risk of dental caries?
> E: upregulation of ammonia production from arginine and urea
What bacterium lacks peptidoglycan and is the agent of the most sexually transmitted infections, characterized by mucopurulent discharges?
> C: Chlamydia trachomatis
Which organism is an obligate intracellular pathogen?
> A: Chlamydia trachomatis
17 Which form of Chlamydia replicates within a host cell?
Answer 1: reticulate body
: 18 Bacteria of which genus are transmitted to humans by bites of infected ticks? 1/1
Rickettsia
What is a symptom of late stage, chronic disease associate with Borrelia burgdorferi?
Arthritis
20 What is uniquely associated with congenital syphilis?
> E: mulberry molars
Name a bacterium that may be detectable by an acid-fast staining test of a sputum smear. Answer: __1__
Answer 1: Mycobacterium tuberculosis
Which of the following is true for Mycobacterium tuberculosis?
> C: the bacterium exhibits a very slow growth rate (doubling time of 1 day)
23 What is a property of the bacterial agent of Legionnaires’ disease?
> D: lives in amoeba in water sources within ventilation systems
Name a bacterium that survives in alveolar macrophages. Answer: __1__
Answer 1: Mycobacterium tuberculosis
What type of virulence factor of Haemophilus influenzae serotype b is specifically correlated with the ability of these bacteria to cause systemic infections?
Capsule B
This Gram-negative coccobacillus is transmitted zoonotically via fleas and eventually infects lymph nodes, producing characteristic swellings called “bubos.”
Answer 1: Yersenia pestis
27 Which of the following is true about Bacillus anthracis?
> B: produces a metallo-protease called lethal factor
Which Clostridium species is part of the normal human bacterial flora? Answer: __1__
C. difficle
29 Botulism results in 1/1
> E: flaccid muscle paralysis due to blocking release of the neurotransmitter acetylcholine
These gram positive rods establish themselves in the throat and kill cells by expressing a toxin that ADP- ribosylates elongation factor 2, causing inhibition of cellular translation.
> C: Corynebacterium diphtheriae
What is a property of the dissaccharide-tetrapeptide component of bacterial peptidoglycan that is the tracheal cytotoxin of Bordetella pertussis?
> B: it is shed from bacterial cells instead of being absorbed and recycled
32 The ability of Pseudomonas aeruginosa to produce a biofilm is dependent on 1/1
> B: alginate production
33 What pathogen resides in the stomach and induces the host to secrete urea through the mucosal epithelium?
Answer 1: Helicobacter pylori
Which enteric bacterium is acquired as a zoonotic infection, often from undercooked chicken, and causes a mild, self-limiting gastroenteritis?
> E: Campylobacter jejune
What is a property of cholera toxin and the system for spreading the genes encoding it?
> D: the toxin genes are encoded in a phage genome
Which of the following is true about cholera?
> B: supportive rehydration therapy is the main method used for treatment
Which enteric bacterium can invade M cells in the gut, survive in macrophages, and eventually infect many different organs in the body?
> A: Salmonella enterica serovar typhi
L I 38 Most cases of cytitis (bladder infections) are caused by which bacterial genus? 1/1
> A: Escherichia
L I 39 What is the effect of shiga toxin on the host? 1/1
> C: removal of a specific adenine base from 28S rRNA
Hemolytic uremic syndrome is a complication of infection by which organism?
> B: Escherichia coli O157:H7
Which programmed alteration of bacterial cell-surface protein expression is due to recombination of silent gene loci into the expressed gene locus for the protein?
> A: antigenic variation
Which of the following is the mostly likely characteristic of Campylobacter jejune?
> C: acquired as a zoonotic infection, often from undercooked chicken, and causes a mild, self-limiting gastroenteritis
To what surface feature of enteric bacteria does the term H-antigen refer?
flagella
What is not a property associated with Salmonella enterica serovar typhi?
> C: produces a cholera-like toxin
Which bacterium produces the vast majority (70-90%) of urinary tract infections (bladder infections, for example)?
> B: Escherichia coli
Bacteroides fragilis is the most frequently isolated bacterium from abscesses caused by intestinal bacteria. This is partly because
> D: its ability to resist phagocytosis
Which of the following is not a virulence factor for Helicobacter pylori?
> D: Shiga-like toxin
Shiga toxin
> C: removes a specific adenine base from 28S rRNA, stopping translation
Which of the following is not a property of Pseudomonas aeruginosa?
> E: obligate intracellular pathogen
These gram positive pleiomorphic rods produce a pseudomembrane in the throat that can block the airway.
> C: Corynebacterium diphtheriae
Clostridium botulinum produces an A-B exotoxin that blocks the release of which neurotransmitter from axon endings at neuromuscular junctions?
> A: acetylcholine
Which Clostridial species is part of the normal human bacterial flora?
> B: Clostridium difficile
Which organism produces alpha toxin (a lecithinase-phospholipase C) and theta toxin (a hemolytic toxin), that partially account for the organism’s tissue-destructiveness that often requires amputation to save the patient’s life?
> C: Clostridium perfringens
Which of the following best describes tetanospasmin, a virulence factor for Clostridium tetani?
> D: A-B exotoxin that blocks release of the neurotransmitter glycine
This Gram-negative coccobacillus is transmitted zoonotically mainly from contact with wild animals such as birds, rabbits, or tick bites. The bacteria are able to grow in macrophages, resulting in systemic spread that can lead to ulceroglandular, oculoglandular, and pulmonary infections. A vaccine is available for high-risk individuals.
> B: Francisella tularensis
What virulence property does Haemophilus influenzae capsule b confer on these bacteria?
> A: allows the bacteria to cause systemic infections
What bacterium lives inside amoeba in the environment and is typically transmitted by an aerosol route to humans through ventilation systems in buildings?
> A: Legionella pneumophila
This Gram-negative coccobacillus is transmitted zoonotically via fleas and eventually infects lymph nodes, where it can cause a purulent infection. In some individuals the bacteria can subsequently spread to the lungs and be
transmitted by aerosol from human to human.
> A: Yersinia pestis
Which of the following is true for cord factor of Mycobacterium tuberculosis?
> B: is a glycolipid that adheres to cell surface mycolic acids
Which of the following is true for leprosy?
> A: individuals normally clear the bacterial agent via cell-mediated immunity