Exam 3 Flashcards
(20 cards)
What are the functions of the 3 zones of the respiratory system?
- ORONASAL ZONE (OZ) - humidifies and warms air, filters air (slows airflow)
- CONDUCTING ZONE (CZ) - filters air, further slows air, some biotransformation
- RESPIRATORY ZONE (RZ) - gas exchange
What layers of the respiratory membrane must a toxicant traverse?
- Fluid layer with surfactant
- Alveolar epithelium
- Epithelial basement membrane
- narrow interstitial space
- Capillary basement membrane
- Capillary endothelial membrane
How do pulmonary and systemic circuits differ in regards to O2 and CO2 content?
What are the components of the circulatory system?
What are the similarities btwn clinical signs seen with rapid-acting vs. slow-acting respiratory irritants?
What are the differences btwn clinical signs seen with rapid-acting vs. slow-acting respiratory irritants?
What do differences between clinical signs w/ rapid/slow acting respiratory irritants exist?
What are decontamination steps to consider for exposure to respiratory irritants?
What is the concentration-related progression of signs from H2S exposure?
How are hypoxemia and hypoxia defined?
What mechanisms of action would cause hypoxia? Hypoxemia?
How do simple asphyxiants differ from systemic asphyxiants??
What is the progression of signs associated with decreasing concentrations of inhaled oxygen?
What are different ways that some systematic asphyxiants interfere with oxygen transport?
How do some systematic asphyxiants interfere with cellular respiration?
How do CO, CN, H2S and methemoglobin inducers interfere with normal respiratory functioning?
How does hyperbaric oxygen therapy work in treating several of the systemic asphyxiants?
How does hydroxocobalamin wowrk in treating CN toxicosis?
What role does the enzyme roadnese play in detoxifying CN and in the mechanism by which hydroxocobalamin works?
