Exam 3 Flashcards

1
Q

fat soluble vs water soluble vitamins

A

fat: ADEK
water: BC

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2
Q

fortification

A

process of adding nutrients to foods
added nutrients are generally not food in the foods or are added in much larger amounts

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3
Q

enrichment

A

adding nutrients back to foods that have lost nutrients due to processing

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4
Q

dietary supplements

A

cannot replace the benefits of a diet containing a wide variety of foods

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5
Q

vitamins in the mouth

A

chewing breaks food into small particles, helping to release vitamins

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6
Q

vitamins in the stomach

A

digestion releases vitamins, some niacin is absorbed

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7
Q

vitamins and the gallbladder

A

releases bile which emulsifies fat and helps absorb fat-soluble vitamins

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8
Q

vitamins and the pancreas

A

secretes digestive enzymes that help release vitamins

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9
Q

fat soluble vitamins in the small intestine

A

incorporated into micelles and absorbed via simple diffusion
inside the mucosal cells, they are packaged in chylomicrons, which enter the lymph

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10
Q

water soluble vitamins in the small intestine

A

absorbed directly into the blood
many depend on active transport or must bind to specific molecules in the GI tract

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11
Q

bioavailability

A
  • vitamins must be absorbed by the body in order to perform
  • fat soluble vitamins require fat
  • water soluble may require specific molecules/active transport
    some
  • some vitamins are absorbed in inactive provitamin or vitamin precursor forms that must be converted to active forms by the body
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12
Q

water soluble storage and excretion

A

easily excreted, except B12
stores can be rapidly depleted, so must be consumed regularly

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13
Q

fat soluble storage and excretion

A
  • stored in the liver and fatty tissue so it takes longer for a deficiency to develop
  • increased risk for toxicity
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14
Q

coenzymes

A
  • vitamin combines with chemical group to form functional coenzyme
  • functional coenzyme combines with incomplete enzyme to form active enzyme
  • active enzyme binds to one or more molecules and accelerates the chemical reaction to form new molecules
  • enzyme and coenzyme (vitamin) can be reused or separated
  • essential for energy metabolism
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15
Q

is fresh fruit better?

A
  • canned can provide an available, affordable source of nutrients
  • fresh can be lower in nutrients due to transport time
  • frozen can minimize nutrient loss
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16
Q

thiamin/B1

A
  • assists in energy production, carb metabolism, production of ribose, health of nervous system
  • beriberi: deficiency
  • wernicke-korsakoff: deficiency in alcoholics
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17
Q

riboflavin

A
  • easily destroyed by heat and light
  • important in citric acid cycle and for assisting with absorption of other vitamins
  • FAD and FMN are coenzyme forms
  • Ariboflavinosis: deficiency
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18
Q

niacin

A
  • can be synthesized from tryptophan
  • important in production of energy and metabolism
  • two forms: nicotinic acid and nicotinamide
  • two active coenzymes: NAD and NAPD
  • Pellagra: deficiency; symptoms are dermatitis, diarrhea, dementia, death
  • toxicity from supplements: elevated blood pressure, cardiac arrhythmia, nausea, vomiting, elevated blood sugar levels, impaired liver function
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19
Q

biotin

A

functions as a coenzyme in energy metabolism
avidin in raw eggs destroys biotin
deficiency: dermatitis

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20
Q

vitamin B6

A
  • called pyridoxine and comprises a group of compounds including pyridoxal, pyridoxine, and pyridoxamine
  • can be converted to pyridoxal phosphate, which is required for many enzyme reactions in the body
  • anemia: deficiency due to impaired hemoglobin synth and neurotransmitter issues
    toxicity from supplements: irreversible nerve damage
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21
Q

folate (folic acid)

A
  • folate enzymes needed for DNA synthesis and the metabolism of some amino acids
  • low intake in early pregnancy is associated with an increased risk of NTDs
  • low intake associated with increased risk of heart disease related to the metabolism of homocysteine
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22
Q

vitamin B12

A
  • necessary for proper absorption of iron in the body
  • most readily absorbed from animal products, vegan diets need to be supplemented with readily absorbable forms of B12
  • atrophic gastritis may lead to deficiencies
  • pernicious anemia: deficiency, form of anemia that does not respond to iron supplementation
  • excessive intake of folic acid can mask B12 deficiencies
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23
Q

vitamin C

A
  • known as ascorbic acid or ascorbate
  • can be destroyed in food by oxygen, light, heat, contact with copper or iron cookware
  • antioxidant in the body
  • helps maintain the immune system
  • important in the production of collagen
  • aids in iron absorption
  • deficiency: scurvy
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24
Q

malabsorption of fat soluble vitamins

A
  • fat malabsorption leads to deficiencies of fat soluble vitamins
  • alcohol abuse and intestinal diseases affect absorption of some B vitamins
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25
Q

vitamin A

A
  • found preformed, from animal products or supplements, or in precursor form, from plant foods
  • key role in night vision, cell differentiation, growth regulation
  • retinoids: reformed vitamin A compounds; derivative of retinoic acid is used for skin
  • carotenoids: precursors to vitamin A found in plants
    hypercarotenemia: turn orange
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26
Q

vitamin D

A
  • 80% of vitamin D consumed is incorporated into micelles
  • no RDA due to variation in sunlight exposure
  • AI: 5 micrograms for under 51, 10 - 15 for over
  • light skinned can produce from casual sun
  • infants are born w it but recommended supplementation
  • increases calcium absorption
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27
Q

vitamin D deficiency and toxicity

A
  • rickets: deficiency in children
  • ostromalacia: deficiency in adults
  • deficiency means dietary Ca cannot be absorbed efficiently -> improper bond mineralization and abnormalities in bone structure
  • over supplementation: high blood and urine Ca concentration, depositing Ca in blood vessels and kidneys, CV damage, death
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28
Q

vitamin K

A
  • named for koagulation; Danish word for coagulation
  • phylloquinone: vitamin K in plants
  • menaquinone: vitamin K in animals and formed by bacteria
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29
Q

vitamin K deficiency

A
  • rare in the US
  • abnormal blood coagulation
  • excess vitamin A and E interferes with vitamin K
  • newborns are injected with vitamin K, breastmilk is a poor source
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30
Q

vitamin K absorption, storage, and excretion

A
  • absorption requires bile and pancreatic enzymes
  • 80% absorbed in small intestine
  • 10% of menaquinones synthesized by intestinal bacteria is absorbed in colon
  • stored in liver and incorporated into lipoproteins
  • excretion is primarily by bile
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31
Q

vitamin K and antibiotics

A
  • destroy intestinal bacteria
  • inhibit vitamin K synthesis and absorption
  • potential for excessive bleeding
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32
Q

major mineral vs minor

A

major: needed in over 100 mg/day or are present in over 0.01% of body weight

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33
Q

compounds that interfere with absorption

A

phytates can limit Ca, Zn, Fe, Mg
Oxalates can limit Ca, Fe
Tannins can limit Fe

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34
Q

minerals as cofactors

A
  • bind to incomplete enzymes to form complete enzyme
  • can be reused or separated from enzyme
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35
Q

calcium functions

A
  • provide structure to bones and teeth and has important regulatory roles
  • in fluid, plays a role in nerve transmission, muscle contractions, blood pressure regulation, release of hormones
  • most abundant mineral in body
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36
Q

osteoporosis

A

low bone mineral density/mass

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37
Q

calcium absorption

A
  • high concentration allows for absorption by passive diffusion
  • low/moderation concentration requires active transport
  • vitamin D turns on synthesis of Ca transport proteins, which shuttle Ca from lumen across the mucosal cell
  • Ca pump requires energy to move Ca from mucosal cell into blood stream
  • bioavailability decreased in the presence of tannins, fiber, phytates, oxalates
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38
Q

calcium regulation

A

high blood Ca: triggers calcitonin release from thyroid gland, which inhibits Ca release from bones
low blood Ca: triggers PTH release from parathyroid gland, which promotes Ca reabsorption by kidney, stimulates activation of vitamin D by kidney, and stimulates Ca release from bone. active vitamin D increases intestinal Ca absorption

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39
Q

phosphate

A

-1% of adult body, 85% in bones and teeth
- important component of molecules with structural or regulatory toles
- ATP
- more readily absorbed than Ca
- deficiency can lead to bone loss, weakness, loss of appetite
- toxicity is rare, but can lead to bone resorption

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40
Q

magnesium

A

-50-60% found in bond, rest is in cells
- cofactor for over 300 enzymes, necessary for generation of energy from carbons, lipids, and proteins
- deficiency: rare, occurs with alcoholism, malnutrition, kidney and GI disease, and diuretics. may cause nausea, muscle weakness and cramping, mental derangement, changes in blood pressure and heart beat

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41
Q

sulfur

A
  • found in protein foods and sulfur containing amino acids in vitamins
  • sulfur containing AA (methionine, cysteine) are needed for protein synthesis
  • also found in nonfood additives
  • vitamins thiamin and biotin contain sulfur
42
Q

trace minerals

A

Fe, Zn, Cu, Mn, Se, I, F, Cr, Mb
- difficult to study bc difficult to remove from diet
- rate of bioavailability is a concern for trace elements

43
Q

iron absorption and function

A
  • absorbed into intestinal mucosal cells
  • essential for delivery of oxygen to cells
44
Q

hemoglobin

A
  • iron containing component of blood
  • most of the iron in the body
  • heme iron: from animal products, more efficiently absorbed
  • nonheme iron: from plant products, iron cookware
45
Q

ferritin, transferrin, hemosiderin

A
  • ferritin: major iron storage protein
  • transferrin: iron transport protein in the blood
  • hemosiderin: insoluble iron storage compound produced by the body when iron exceeds the storage capacity of ferritin
46
Q

iron deficiency

A
  • hemoglobin cannot be produced
  • iron deficiency anemia: when there is insufficient hemoglobin, red blood cells are microcytic and hypochromic and unable to deliver sufficient oxygen to the tissues
  • risk: women with menstruation, pregnant, infants, children, teens, low meat diets, high phytates and fiber diets, poverty, intestinal parasites
47
Q

iron toxicity

A
  • poisoning can be life threatening, can damage intestinal lining and cause abnormalities in body pH, shock, and liver failure
  • overload can happen over time and accumulates in tissues like heart and liver
  • hemochromatosis: most common form of iron overload
48
Q

zinc

A
  • essential for growth and development
  • animal sources absorbed better than plant
  • can be bound by phytates, affecting bioavailability
  • most abundant intracellular trace element
  • toxic in excess
  • involved in functioning of over 300 enzymes, including superoxide dismutase which is important for protecting cells from free radicals
49
Q

copper

A
  • important in helping to prevent certain types of anemia
  • richest source is organ meat, also in seafood, chocolate, nuts, seeds, whole grain foods
  • Zn can decrease bioavailability
  • metallothionein binds to Cu, limiting absorption; synthesis is stimulated by high levels of Zn
50
Q

manganese

A
  • sources: whole grains and nuts
  • constituent of some enzymes and an activator of others
  • Mn requiring enzymes are involving in AA, CHO, and cholesterol metabolism, cartilage formation, urea synthesis, and antioxidant protection
  • needed for the activity of a form of superoxide dismutase
51
Q

selenium

A
  • Se content of plant foods depends on soil
  • deficiency: muscular discomfort and weakness, can lead to Keshan disease, affective the heart and muscle
  • high intake: brittle hair and nails
52
Q

iodine

A
  • content depends on soil where plants are grown or where animals graze
  • soil near ocean is higher in I
  • most dietary I comes from iodized salt (fortified, natural sea salt may be low)
  • more than half I in the body is in thyroid gland
  • essential for thyroid hormones, including thyroxine
53
Q

chromium

A
  • sources: brewer’s yeast, liver, nuts, whole grains, cooking in stainless steel
  • involved in carb and lipid metabolism
  • enhances glucose uptake by the cell
54
Q

fluoride

A
  • important for dental health, makes teeth resistant to decay
  • present in small amounts in almost all soil, water, plants, and animals
  • sources: fluorinated water, tea, marine fish eaten with their bones such as canned salmon or sardines, topical toothpaste
  • Ca rich foods reduce F bioavailability
  • deficiency makes teeth susceptible to dental caries
  • fluorosis: toxicity, teeth appear mottled
55
Q

calcium dri

A

1000 mg/day

56
Q

Na and Cl in the diet

A
  • necessary to maintain extracellular fluid volume and plasma osmolarity
  • 98% absorbed, excess excreted in urine
  • major adverse effect is elevated blood pressure, which is risk factor
  • most NaCl in the diet is added during processing
  • immediate, deliberate reduction is needed
57
Q

water function

A
  • lubricant and cleanser (tears, synovial fluid in joints, saliva, spinal fluid)
  • regulating body temp by holding onto heat and changing temp slowly
  • metabolism: hydrolysis and dehydration
  • osmosis in response to concentration of dissolved substances
58
Q

water in blood

A
  • blood is 90% water
  • blood transports O2 and nutrients to cells and removes CO2 and waste products
59
Q

thirst mechanism

A
  • decrease in blood volume and increase in solute concentration in blood
  • dry mouth + brain signals = thirst
  • consumption of water increases blood volume and decreases solution concentration
60
Q

antidiuretic hormone

A
  • in response to decrease in blood volume and increase in solute concentration, pituitary gland secretes ADH
  • ADH signals kidneys to increase water reabsorbed into blood, less water lost in urine
61
Q

3 principal electrolytes

A

Na: major pos extracellular
K: major pos intracellular
Cl: major neg extracellular

62
Q

electrolyte

A
  • pos and neg charged ions that conduct an electrical current in solution
  • distribution affects distribution of water throughout the body
  • nerve conduction
63
Q

Na K ATP ase

A

Na extracellular, K intracellular

64
Q

blood pressure regulation

A
  • decrease in blood pressure triggers kidneys to release enzyme renin
  • renin converts angiotensinogen to angiotensin I which is activated to angiotensin II by ACE
  • Angiotensin II increases blood pressure by constricting walls of blood vessels and stimulates aldosterone from adrenal gland
  • aldosterone increases Na reabsorption by kidneys
  • water follows Na, decreasing urine output, increase in blood pressure
65
Q

electrolyte deficiency

A

fluid loss and medications

66
Q

electrolyte toxicity

A

K supplements or renal disease can cause toxicity
Na toxicity is rare as fluid is usually increased to compensate

67
Q

hypertension

A

high blood pressure where there is an increase in the pressure of the blood against the arterial wall

68
Q

overload principle

A

assumes the body will adapt to the stresses placed on it

69
Q

aerobic exercise

A
  • includes endurance exercises that increase heart rate and requires oxygen in metabolism
  • regular aerobic exercise strengthens the heart muscle, increases stroke volume, and decreases the resting heart rate
70
Q

aerobic capacity

A

body’s max ability to generate ATP by aerobic metabolism during exercise
AKA VO2 max

71
Q

hypertrophy

A
  • stress or overload during exercise causes muscles to adapt by increasing in size and strength
  • people who are fit have a greater proportion of lean body tissue than those who are not fit
72
Q

atrophy

A

when muscles are not used, they become smaller and weaker

73
Q

aerobic metabolism

A
  • metabolism in the presence of oxygen
  • glucose, fatty acids, and amino acids are completely broken down to form CO2 and H2O and to produce ATP
74
Q

anaerobic metabolism

A
  • metabolism in the absence of oxygen
  • each glucose produces two ATP
  • when oxygen cannot be supplied quickly enough to the tissues
  • AKA anaerobic glycolysis
75
Q

instant energy

A
  • energy from stored ATP
  • creatine phosphate broken down to form more ATP
76
Q

short term energy

A

anaerobic metabolism of glucose, obtained either from blood or muscle glycogen

77
Q

long term energy

A

oxygen delivery to muscles has increased enough to support aerobic metabolism, which uses fatty acids and glucose to produce ATP

78
Q

sports nutrition issues

A

unhealthy weight loss practices
making weight
female athlete triad
eating disorders
healthy weight gain
sports anemia
dehydration

79
Q

micronutrient needs to athletes

A

can meet needs through diet
special attention: B vitamins, antioxidant vitamins like C and E, iron, calcium, vitamin D

80
Q

sports fluid needs

A
  • water needed to eliminate heat, transport O2 and nutrients to the muscles, and to remove waste
  • adult loses 4.5C of water per day through evaporation
  • if heat cannot be lost from the body, temp rises and performance and health can be jeopardized
  • even with regular consumption, it may not be possible to consume sufficient fluid
81
Q

dehydration

A

when water loss is great enough for blood volume to decrease
reduces the body’s ability to deliver oxygen and nutrients to muscles

82
Q

hyponatremia

A

replacing just water dilutes sodium

83
Q

common nutrient deficiencies

A

iron, vitamin A, iodine, zinc, selenium, calcium

84
Q

sustainable agriculture

A

food production methods that prevent damage to the environment and allow the land to restore itself so food can be produced indefinitely

85
Q

local food

A

can minimize energy costs and pollution due to food transport

86
Q

organic foods

A

minimally processed and ecologically packaged can minimized environmental impacts

87
Q

biotechnology

A
  • uses techniques to manipulate DNA for the purpose of changing the characteristics of an organism or creating a new product
  • speeds up the process of introducing new traits that can be passed through generations
88
Q

applications of biotech

A
  • improving crop yield by producing crops that are herbicide resistant, insect resistant, and disease resistant
  • improving nutritional quality, food safety, production
  • combating human disease
89
Q

consumer safety of genetically modified foods

A
  • concern that it may cause health problems and cause environmental damage
  • allergens and toxins may be introduced or created
  • changing nutrient content
  • antibiotic resistance
  • GM foods do not currently carry special labels
  • FDA has focused on the characteristics of a food, not how it’s produced
90
Q

environmental concerns of GM foods

A

gene diversity may change, gene banks and seed banks established as precautions
superweeds and superbugs may be created

91
Q

FDA vs USDA vs EPA

A

FDA: regulated safety and labeling
USDA: regulates agricultural products and research concerning development of new plant varieties
EPA: regulates GM foods that are able to protect themselves from insects or disease

92
Q

orthorexia nervosa

A

fixation of the virtue of food or unhealthy obsession with healthy eating

93
Q

1943: basic seven

A

people don’t eat nutrition, they eat food

94
Q

NOVA

A
  • published system that groups foods according to the nature, extent, and purposes of the industrial processes they undergo
  • seeks to relate food processing as the primary driver of diet quality
95
Q

ultraprocessed foods

A

made from processed substances extracted or refined from whole foods with little or not whole foods

96
Q

nutrient profiling

A

classify or rank foods according to their nutritional composition for reasons related to preventing disease and promoting health

97
Q

dietary guidelines committee

A
  • considers original systematic reviews, reports, NHANES, only human studies, food pattern modeling analysis
  • issues technical report with recommendation, DHHS/USDA uses this to develop dietary guidelines
98
Q

healthy pattern limits

A

sat fat: <10% kcal/day
trans fat: as low as possible
added sugars: <10% kcal/day
sodium: <2300 mg/day

99
Q

protein and nitrogen

A

g protein = g N * 6.25

100
Q

vitamin E

A

antioxidant
deficiency: broken RBC, nerve damage