Exam 3 Flashcards
1
Q
How to turn OH to CHO
A
DMP
2
Q
How to turn carboxylic acid to Ester
A
EtOH, cat.HCl,
MeOH, cat.HCl
3
Q
Direct Alkylation of Mono ester
A
1) LDA/THF
2) Allyl Bromide
4
Q
Direct Alkylation of Diester
A
1)NaOEt
2) Allyl Bromide
5
Q
Ester reduction to primary alcohol
A
1)LiAlH4
2)H30
6
Q
Deprotonation to addition at primary position of monoketone
A
1)LDA/THF
2) MeI
7
Q
OH to CO2H
A
CrO3, H3O
8
Q
Reduction of Amide to Amine
A
1) LAH, H2O
9
Q
Adding NMe2 to carboxylic acid
A
1.) DCC
2.) Me2NH
10
Q
Turning amide to nitrile
A
SOCl2
11
Q
Ester to Aldehyde
A
1)DIBAL
2) H3O+
12
Q
How to add R groups to ester then de carboxylic (H3O+)
A
1) 3 equiv RMgBr
2) H3O+
13
Q
Halide -> CO2H
A
1) Mg, ether
2) CO2
3) H3O+
