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CNS > Exam 3 > Flashcards

Exam 3 Flashcards

1
Q

Cyclobenzaprine Brand

A

Amrix, Flexeril, Fexmid

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2
Q

Tramadol Brand

A

Conzip, Qdolo

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3
Q

Amitriptyline Brand

A

Elavil

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4
Q

Nortriptyline Brand

A

Pamelor

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5
Q

Pregabalin Brand

A

Lyrica

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6
Q

Hydrocodone/APAP Brand

A

Lortab, Norco

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7
Q

Oxycodone Brand

A

OxyContin, Roxicodone, Xtampza

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8
Q

Morphine Sulfate Brand

A

MS Contin, Kadian

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9
Q

Naproxen Brand

A

Naprosyn

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10
Q

Ibuprofen Brand

A

Motrin, Advil

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11
Q

Cyclobenzaprine Class

A

Muscle Relaxant

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12
Q

Cyclobenzaprine MOA

A

Potentiates NE and binds to serotonin receptors, reducing spasticity

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13
Q

Cyclobenzaprine Dose

A

5-10 mg PO TID
ER: 15 mg ER qD

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14
Q

Cyclobenzaprine CI

A

Elderly, MI, Hepatic disease, arrhythmia, heart block, CHF

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15
Q

Tramadol Class

A

Opioid Agonist

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16
Q

Tramadol MOA

A

Binds mu receptors and weakly inhibits NE/serotonin reuptake, producing analgesia

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17
Q

Tramadol Dose

A

50-100 mg PO q4-6h

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18
Q

Tramadol CI

A

MAOi use, respiratory depression, asthma, GI obstruction, seizure disorder, head injury, alcohol use

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19
Q

Tramadol BBW

A

High addiction/misuse risk
Opioid analgesic REMS
Life threatening resp. depression
Concomitant use with BZD

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20
Q

Amitriptyline Class

A

Tricyclic Antidepressant

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21
Q

Amitriptyline MOA

A

Inhibits NE/serotonin reuptake

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22
Q

Amitriptyline Dose

A

50-150 mg PO qHS

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23
Q

Amitriptyline CI

A

MI recovery

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24
Q

Amitriptyline BBW

A

Suicidal thoughts

25
Q

Nortriptyline Class

A

Tricyclic Antidepressant

26
Q

Nortriptyline MOA

A

Inhibits NE/serotonin reuptake

27
Q

Nortriptyline Dose

A

50-150 mg PO qHS

28
Q

Nortriptyline CI

A

Brugada syndrome and acute MI

29
Q

Nortriptyline BBW

A

Suicidal thoughts

30
Q

Pregabalin Class

A

Anticonvulsant

31
Q

Pregabalin MOA

A

Binds to alpha2-delta subunit of calcium channels, reducing NT release

32
Q

Pregabalin Dose

A

IR: 50-100 mg PO TID
ER: 165-330 mg PO qD

33
Q

Pregabalin CI

A

Renal Disease

34
Q

Hydrocodone/APAP Class

A

Opioid combo, narcotic + non-narcotic

35
Q

Hydrocodone/APAP MOA

A

Binds to various opioid receptors + centrally acting non opioid analgesic

36
Q

Hydrocodone/APAP Dose

A

2.5-10 mg PO q4-6h PRN

37
Q

Hydrocodone/APAP CI

A

Respiratory depression, asthma, GI obstruction

38
Q

Hydrocodone/APAP BBW

A

Avoid doses of APAP >4000 mg per day

39
Q

Oxycodone Class

A

Opioid agonist

40
Q

Oxycodone MOA

A

Binds to various opioid receptors, producing analgesia and sedation

41
Q

Oxycodone Dose

A

Individualized Dosing

42
Q

Oxycodone CI

A

MAOi use, resp. depression, asthma, GI obstruction, seizure disorder, head injury, alcohol use

43
Q

Oxycodone BBW

A

High addiction/misuse risk
Opioid analgesic REMS
Life threatening resp. depression
Concomitant use with BZD

44
Q

Morphine Class

A

Opioid Agonist

45
Q

Morphine MOA

A

Binds to various opioid receptors, producing analgesia and sedation

46
Q

Morphine Dose

A

Dose varies

47
Q

Morphine CI

A

MAOi use, resp. depression, asthma, GI obstruction, seizure disorder, head injury, alcohol use

48
Q

Morphine BBW

A

High addiction/misuse potential
Resp. depression
Adverse CV events
Death

49
Q

Naproxen Class

A

NSAID

50
Q

Naproxen MOA

A

Inhibits COX, reducing prostaglandin and thromboxane synthesis

51
Q

Naproxen Dose

A

IR: 250-500 mg PO q12h
ER: 750-1000 mg PO qD

52
Q

Naproxen CI

A

ASA/NSAID induced asthma
Pregnancy (2/3)

53
Q

Naproxen BBW

A

CV/GI events

54
Q

Ibuprofen Class

A

NSAID

55
Q

Ibuprofen MOA

A

Inhibits COX, reducing prostaglandin and thromboxane synthesis

56
Q

Ibuprofen Dose

A

300-800 mg TID-QID

57
Q

Ibuprofen CI

A

ASA/NSAID induced asthma
Pregnancy (2/3)

58
Q

Ibuprofen BBW

A

CV/GI events

CNS (3 decks)

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