Exam 3 Flashcards
adult cognition is the process of…
Acquiring
Storing
Sharing
Using information
components of adult cognition
- Language
- Thought
- Memory
- Executive function
- Organization (gather info)
- Regulation (evaluate and change behavior)
- Judgment
- Attention
- Perception
adult cognition in action
- Orientation
- Problem solving
- Psychomotor ability
- Reaction time
- Social intactness
cognition physiological changes with age
Neuron loss
- most pronounced in cerebral cortex
Brain atrophy
- decreased weight
Dendrites atrophy
- impaired synapse
- changed transmission of dopamine, serotonin, and acetylcholine
not consistent with deteriorating mental function
Slowing is NORMAL (not processing as quickly
- IMPAIRMENT IS NOT NORMAL (not being able to remember things at all)
cognitive reserve (CR)
Ability to compensate for age-related changes
“use it or lose it” - applied to cognitive function as well as physical health
- based on the concept of neuroplasticity (capacity of the brain to change in response to stimuli)
maximizes cognitive reserve
- Engage in cognitive, sensory, and motor activities
- Engage in meaningful social interaction regularly
fluid intelligence
Native intelligence or “street smarts”
Biologically determined skills INDEPENDENT of learning or experience
- thinking, inductive reasoning, abstract thinking, and integration
Ability to identify and draw conclusions
crystallized intelligence
“book smarts”
Knowledge and skills acquired during life
- verbal meaning, word association, social judgment, number skills
classic aging pattern
- Fluid intelligence decreases while crystallized intelligence remains stable
- Related to speed of cognitive processing and slower reaction time
learning late in life
basic intelligence remains unchanged with increasing years
cognitive assessment
- Evaluation of cognitive function requires formal focused assessment
- Complete assessment, including lab workup, should be performed to rule out any medical causes of medical impairment
myths about the aging brain
box 5.1, p 57
tips to improve memory
table 5.1, p 59
3 components to memory
- Immediate recall
- Short term memory
- Remote or long-term memory
memory retrieval
Recall of newly encountered information decreases with age
- Memory declines noted for complex tasks and strategies
age-associated memory impairment (AAMI)
- Considered normal memory loss (general slowness in processing, storing, and recalling new information and difficulty in remembering names and words)
- Offset with cognitive stimulation and memory training
mental health and aging
- Nearly 20% over 55 y/o experience mental health disorders that are not part of normal aging
- Underreported and not well researched
- Can be affected by cognitive and affective functioning earlier in life
common mental disorders later in life
- Depression
- Anxiety
- Mood disorders
- Alcohol abuse and dependence
stress overload
- Increased by changing environmental needs and reduced of biopsychosocial homeostatic resilience
- Diminishes ability to cope effectively
effects of stress
- Reduces coping ability
- Impairs neuroendocrine response that blunts immune function
- Research on psychoneuroimmunology explored relationship between stress and various health conditions, cancers, Alzheimer’s disease, frailty, an functional decline - pro inflammatory cytokines
flourishing despite adversity (tend to develop as you age)
Resilience
- successfully adapting to difficult and life challenging experiences
- positive interpersonal relationships
- high self-esteem and self-efficacy
- sense of purpose
- creativity and sense of humor
control, commitment, & challenge
Hardiness
- stress is a challenge and an opportunity for growth
- social connectedness
- confronting problems head-on
- extending oneself to others
- spiritual grounding
toolbox of self-control skills & belief that the tools may be used effectively
Resourcefulness
- self-control
- self-direction
- self-efficacy
Coping
- Coping may contribute more to health of older adults because they use it to optimize their resources
- Coping strategies are factors that help individuals maintain psychosocial balance during stressful periods
- Includes identifying stressor – good, bad, indifferent
- Using skills & resources
- Using past experiences as a resource
- Using these appropriately
Assessment for Coping
- Risk factors of life transition, loss, and loss of social support
- History of ability to cope with stress and life events
- Assessment of cognitive function and/or impairment
- Assessment of substance abuse and suicide risk
Coping Interventions
- Enhancing characteristics of hardiness, resilience, and resourcefulness
- Enhancing functional status and independence
- Promoting sense of control
- Fostering social supports and relationships
- Education regarding available resources
Factors Influencing Mental Health Care
Attitudes & Beliefs
- stigma
- myth that it is normal
Availability & Adequacy of Care
- access
- ability to pay
Care Settings
- place of treatment
- who is providing care (staffing)
Cultural & Ethnic Disparities
- poverty
- language
- cultural understanding
anxiety disorder
NOT part of the normal aging process
- Life events and stressors may contribute to development of anxiety disorders
Associated with:
- excessive healthcare use
- decreased physical activity and functional status
- substance abuse
- decreased life satisfaction
- increased mortality rates
anxiety assessment
- Difficult to diagnose in older adults
- Denial
- Coexisting medical conditions can mimic anxiety
- Common side effect of certain drugs
- Drug and alcohol withdrawal also can cause anxiety symptoms
anxiety interventions
Treatment choices depend on symptoms, specific anxiety diagnosis, comorbid medical conditions, and current medications
Therapeutic relationship between patient and HCP is the foundation for any intervention
anxiety pharmacological treatment
Antidepressants - SSRIs
- First line
Short acting benzodiazepines
- Second line and short, bridge course
Non-benzodiazepine anxiolytic agents
anxiety non-pharmacological interventions
- Cognitive behavioral therapy (CBT)
- Mindfulness-Based Stress Reduction (MBSR)
- Meditation
- Exercise (Yoga)
depression
NOT a normal part of aging
- MOST common mental health problem of late life
- one in ten older adults visiting a physician suffers from depression
- Depression and illness are likely to co-occur
- r/t medical conditions
- Medication SE - ACEI, antidysrhythmic, antibiotics…
depression is associated with
- Major source of morbidity in older adults
- Increased disability
- Delayed recovery from illness and surgery
- Excessive use of health services
- Cognitive impairment
- Decreased quality of life
- Increased suicide and non-suicide related death
etiology of depression
Multifactorial
- Health and chronic conditions (box 28.14, p 357)
- Gender (female)
- Developmental needs
- Socioeconomics
- Environment
- Personality
- Losses
- Functional decline
- Medications (box 28.16, p 357)
presentation of depression in older adults
- Comedic medical conditions strongly related to depression in older adults
- More somatic complaints (physical symptoms)
- Hypochondriasis (constant complaining and criticism)
- Decreased energy and difficulties completing ADLs
- Social withdrawal
- Decreased libido
- Preoccupation with death
- Memory problems
- *Strong association of depression with dementia
- Risk factors for depression in older adults (box 28-16)
depression assessment
- geriatric depression scale (GDS), H&P, functional and cognitive assessment, medication review, lab analysis, comorbid conditions
(box 28.17, p 358)
depression interventions
- If GDS is positive, need further assessment
- Treatment should begin promptly
- Combination of pharmacologic therapy and psychotherapy (CBT) and counseling (BEST)
- Music, dance
medications for depression
SSRIs (fluoxetine, sertraline)
SNRIs - second line (venlafaxine)
- Tailored to specific patient needs
- Trials of alternate medications and psychotherapy required in many patients
- ECT therapy
Avoided: tricyclics, older MAOIs (higher risk of falls)
ECT therapy
Safe therapy for older adult patients at risk for harm due to suicidal ideation, psychotic depression, or severe malnutrition
- Efficacy rates ranging from 60-80%
depression
suicide and older adults
- Older adults account for 15% of population but 20% of suicide deaths
- Higher than any other age group
- White and Native American men have the HIGHEST suicide rate in older adult population
- Older widowers MOST vulnerable
- Up to 75% of older adults who die from suicide visited physician within one month of death (routine depression screening important for all older adults)
suicide assessment
- ANY reference to ending life must be taken seriously
- Establish trusting and respectful relationship
- Behavioral cues (goodbyes, giving away possessions)
suicidal interventions
If suicide risk suspected, as direct questions
- Have you ever thought about killing yourself?
- How often have you had these thoughts?
- Do you have a plan to carry it out/How would you do it?
High risk patients need to be hospitalized
Moderate and low risk treated as outpatients
- adequate social support
- no access to lethal means
substance abuse in older adults
Alcohol
- Often a coping mechanism in old age to deal with loss, anxiety, depression, chronic illness
- Most severe abuse seen in ages 60-80
Gender Issues
- Late onset alcohol abuse associated with illness, retirement, loss of spouse
- White men 4x more likely to abuse alcohol
- Number and impact of older female drinkers expected to increase
Drug effects
- Prescription and OTC medications have many adverse effects when combined with alcohol
Physiology
- Age related changes in water and body fat cause higher blood alcohol levels
- Liver and kidney function interferes with alcohol metabolism and excretion
- Increased risk of GI bleeding
substance abuse assessment
- Screening for alcohol and drug use
- Comorbid conditions may mask decline caused by alcohol
substance abuse interventions
- Must address quality of life and adapt it to meet needs
- Treatment focuses on cognitive and behavioral approaches
- Screening for alcohol and drug abuse
- Education and counseling about alcohol and prescription, OTC, and illicit drug use
- Referral to specialist and community resources
acute alcohol withdrawal
- Life threatening emergency
- Detoxification should be done in inpatient setting
substance abuse concerns
- Misuse of prescription and OTC medications
- Polypharmacy effects exacerbated with alcohol use
- Inappropriate prescribing and ineffective monitoring of controlled substances
delirium
MEDICAL EMERGENCY
- Cognitive changes in older people often labeled as confusion by providers and frequently accepted as a normal part of aging
- Delay in treatment contributes to negative outcomes with delirium
- Associated with increased length of stay, morbidity and mortality, institutionalization, and comorbid illnesses
- Significant distress for patient and family
Assessment tool: CAM
delirium incidence and prevalence
- Occurs in older adults across the continuum of care
- Among medical inpatients, delirium is present on admission to the hospital in 10-31% of older patients
- During hospitalization, 11-42% of older adults develop delirium
- Highest incidence is in ICUs and subacute settings
- Prevalence of delirium in the community is low
delirium superimposed on dementia
- Older patients with NCDs are 3-5x more likely to develop delirium
- Delirium superimposed on NCDs can accelerate the trajectory of cognitive decline and is associated with a high mortality
risk factors for delirium
- Acute illness
- Infections*
- Medications
- Invasive equipment
- Metabolic disturbances
- Dehydration*
- box 29.2
- Alcohol or drug abuse
- Sensory impairments
- Unrelieved pain
- Surgery
- Hip fracture
- Cognitive impairment (hx of dementia)
- Age
Early onset dementia (<60) is more related to genetic susceptibility (if their daily life is impaired, it’s more likely dementia, not delirium)
mild cognitive impairment
Gradual onset with steady decline
In elderly, often seen as a normal part of aging
- Decline - Yes, “forgetfulness”
- Dementia - No
(represent serious pathological alterations)
Any mental status change in older adult warrants a comprehensive assessment
dementia
IRREVERSIBLE state that progresses over years in decline of intellectual function
Clinical features include at least one of the following:
- Aphasia
- Apraxia
- Agnosia
- Disturbances in executive functioning (attention, decision making, consciousness, memory, problem solving)
partial or total loss of the ability to articulate ideas or comprehend spoken or written language
aphasia
partial or total loss of the ability to perform coordinated movements or manipulate objects in the absence of motor or sensory impairment
apraxia
loss of the ability to interpret sensory stimuli, such as sounds or images
agnosia
Alzheimer’s disease (AD)
Most common form of dementia
Age 30-60 (early onset) - less than 5%
- Familial Alzheimer’s disease (FAD) - genetic
Age 60+ (late onset) - accounts for most cases
- Not specifically genetic
- Environmental factors, lifestyle, and genetic mutations
2/3 are women -> r/t “survivor bias”
6th leading cause of death and 3rd most expensive medical condition
Increased number of ß-amyloid proteins (plaques) outside the neuron and accumulation of tau proteins (tangles) inside the neuron
Starts where memories are stored
- Most recent memories lost first d/t issues learning/retaining information
Decrease the risks for neurodegenerative disorders (box 23.11)
preclinical stage of Alzheimer’s disease
NO symptoms
- Biological/neurological changes started
- Amyloid building may be detectable with:
- > PET scan
- > CSF analysis
Mild Cognitive Impairment (MCI) stage of Alzheimer’s disease
Noticeable changes in memory and thinking
- Can be measured
- May not yet effect day-to-day life
- Difficulty managing money issues
- Increased forgetfulness
- > Appointments
- > Social engagements
- > Lose train of thought
- Decision making becomes overwhelming
- Trouble finding way around
- Impulsive
- Irritability/aggression
- Anxiety
- Apathy
Alzheimer’s Dementia stage of Alzheimer’s disease
Multiple changes and deficits now present
Other cognitive aspects:
- word finding
- vision/spatial issues
- impaired reasoning/judgment
At this stage, individuals may:
- Require full-time assistance with ADLs
- Lose awareness of experiences and surroundings
- Have changes in physical abilities
- > Walking, sitting, eating/swallowing
- Have increased difficulty communicating
- Become vulnerable to infections, especially pneumonia
Alzheimer’s disease diagnosis
Decline from previous level of functioning
- Documented exam
Onset was insidious
- Without being specifically apparent
Gradual regression in cognitive abilities
- Beyond what is expected of age and education
AD non-pharmacological interventions
More effective and improve quality of life
Activities, therapies, exercise, sensory stim, reminiscence, environmental design, staffing, lighting, relaxation, distraction, non-confrontational approaches
- Person-centered care
- Foster abilities
- Support limitations
- Ensure safety
- Enhance QOL
- Prevent disability
- Maintain function
- Structured environment
- Promote relationships
AD pharmacological interventions
Aimed at slowing cognitive decline
First Line: Cholinesterase Inhibitors (CIs)
- Acetylcholine -> memory and thinking
- Donepezil (Aricept) -> all stages
- Galantamine (Razadyne) & Rivastigmine (Exelon) -> mild to moderate decline
Other medications:
- Memantine (Namenda) -> used in combination with CIs for learning and memory
- Sleep aids
- Antidepressants
- Antipsychotics
Communication box 29.14
Precipitating factors box 29.17
AD behavior concerns
Anxiety Depression Hallucinations Delusions Aggression Screaming Restlessness Agitation Resistance to care
Progressively Lowered Stress Threshold model (PLST)
box 29.16
Stressors that may trigger symptoms
- Fatigue
- Change in environment, routine, caregiver
- Misleading or inappropriate stimuli
- Demands to perform beyond abilities
- Pain, illness, depression
Care
- Structured to decrease stressors
- Provide safe and predictable environment
Outcomes
- Improved sleep, less sedatives, better nutrition, socialization, decreased anxiety/agitation, care giver satisfaction
Need-Driven Dementia-Compromised Behavior Model (NDB)
box 29.15
Behaviors have meaning and are attempted to communicate
- Interaction between background and proximal factors
Background
- Cognitive changes, gender, ethnicity, culture, education, personality, responses to stress
Proximal - physiologic needs
- Food, pain relief, mood, physical environment (light, noises)
Care
- Manipulate proximal factors
- Maximize strengths
- Minimize limitations of background factors
AD nursing assessment
Behavior and psychological symptoms of dementia (BPSD)
- All behavior is meaningful and expression of need
First rule out medical problems
- > infection, dehydration, pain, fractures, impaction
- > GI/GU problems cause much distress
Consider psychosocial problems
- > fear, discomfort, unfamiliar things, fatigue, depression, loss of control/autonomy, etc.
- > May misinterpret stimuli
AD nursing intervention care: Wandering
Wandering
- Difficult problem to manage
- Not well understood
- Risk -> falls, elopement, injury, death
Things to do:
- Music, exercise, refreshments, social interaction
- Camouflage doorways, enclosed areas for walking, electronic bracelets
60% will wander and become lost at some point
wandering interventions/avoiding getting lost (box 29.25)
AD nursing intervention care: Bathing
Can lead to distressing behaviors
Nursing Actions:
- Explain actions
- Don’t push
- Positive feedback
- Demonstration
- Encourage self-care
- box 29.23
AD nursing care: Nutrition
Older adults with dementia are particularly at risk for weight loss and inadequate nutrition
- Patients need to be fed
- Choke
- Refuse food
Tube feeding at end-stage dementia
- Not generally recommended (not shown to extend life or improve QOL)
- Careful hand feeding -> as they want (box 29.27)
AD care of patient: 4 nursing roles
Magician
- See the world through their eyes
- Use tricks to augment behavior
Detective
- Investigate clues r/t behaviors
Carpenter
- Tools to individualize care
Jester
- Use humor
- Spread joy