Exam 3 Flashcards
Acute incontinence characteristics
acute onset, reversible, may have associated dysuria
types of incontinence
acute, stress, urge, overflow, functional, mixed
types of persistent incontinence
stress, urge, overflow, functional, mixed
stress incontinence
small volumes of leakage caused by increased intra-abdominal pressure
causes of stress incontinence
sphincter problems, TURP
urge incontinence
strong, sudden urge with inability to delay
cause of urge incontinence
overactive bladder contractions
overflow incontinence
due to urinary retention, may be associated with pelvic/abdominal pain
functional incontinence
unwilling or unable to reach toilet
causes of functional incontinence
osteoarthritis, dementia etc
mixed incontinence
usually stress and urge mixed
how to ask about incontinence
do you have bladder problems that are bothersome or do you leak urine
reversible causes of incontinence DISAPPEAR mnemonic
Delirium, improper fluid Intake, Stool impaction, Atrophic vaginitis/urethritis, Psychological problems, Pharmaceuticals, Excess urine output, Abnormal lab values, Restricted mobility
what conditions can cause excess urine output
DM, hypercalcemia, CHF, other volume overload conditions, venous insufficiency when legs elevate
what medications can cause incontinence
diuretics, benadryl, anticholinergics, opioids, calcium channel blockers
what causes atrophic vaginitis
decrease in estrogen levels
causes of fixed incontinence
age-related weakness in pelvic floor or sphincter, obstruction (BPH or prolapse), neurologic, previous surgery/radiation
causes of neurologic incontinence
stroke, spinal cord injury/cauda equina, dementia, Parkinsons? DM, MS
normal bladder capacity
300-600 mL
external bladder sphincter is what kind of muscle
skeletal
what parts of bladder/sphincter is smooth muscle
detrusor, internal sphincter
sympathetic innervation of bladder
L1-L3 closes bladder and inhibits parasympathetics to relax bladder and hold urine in
parasympathetic innervation of bladder
S2-S4 contracts bladder to void
what carries info on bladder fullness to spinal cord
afferent pathways via somatic and autonomic nerves
when does first urge to void bladder occur
150-350 mL
what counterbalances bladder pressure
urethral pressure
under what circumstances does involuntary bladder contraction occur
neurogenic bladder
medications causing incontinence due to reduced control
diuretics, sedatives, tamsulosin (alpha adrenergic blockers), ETOH, caffeine
meds causing incontinence due to urinary retention
anticholinergics, psych meds, alpha agonists, calcium channel blockers
what is considered urinary retention on post-void residual
> 150 mL
Major concern with hematuria
cancer until proven otherwise
cutoff for microscopic hematuria
3 or more RBCs per hpf in 2 of 3 specimens
problem with urine dip re: hematuria
cannot distinguish between myoglobin, hemoglobin, diet
major cause of stress incontinence in men
removal of prostate
causes of hematuria
UTI, urolithiasis, BPH, cancer, vaginal bleeding, vigorous exercise, urethral trauma, nephritic syndrome
high-risk hematuria
smoking, chemical exposure, older than 40, pelvic radiation, analgesic abuse, history of UTIs
what suggests kidney etiology of hematuria
protein, creatinine, casts
upper urinary tract evaluation
CT, IV urography, renal ultrasound
lower urinary tract evaluation
cystoscopy, voided urine cytology
only method of reliably detecting transitional cell carcinoma of bladder/urethra
cystoscopy
definition of asymptomatic bacteriuria
2 consecutive counts of over 100K of the same bacteria
Primary sleep disorders that increase with age
sleep-related breathing disorders, RLS, circadian rhythm disorders
age-related changes of total sleep time, slow-wave sleep, REM sleep
decrease
age-related changes of daytime napping, stages N1 and N2, wake after sleep onset
increase
neck circumference associated with OSA
> 16 inches
which questionnaire is used to evaluate OSA
STOP-Bang
elements of STOP-Bang
Snoring, Tiredness, Observed apnea, high blood Pressure, BMI, Age, Neck circumference, Gender
predisposition to sleep disordered breathing
age over 40, commercial motor vehicle driver, family history, male, obesity, postmenopausal, retrognathia, reduced distance and increased angles from chin to thyroid
periodic limb movement disorders
repetitive, stereotypic leg movements that occur during non-REM sleep
Restless leg syndrome
uncontrollable urge to move legs with an unpleasant sensation that improves with movement
diagnosis of PLMS, RLS
polysomnography for PLMS, RLS is clinical
Possible causes or provoking factors for RLS
iron deficiency, meds (antiemetics, antipsychotics, SSRIs, tricyclics, diphenhydramine)
treatment for RLS
dopamine agonist (pramipexole, ropinirole), gabapentin
rapid eye movement during sleep is associated with what disorders
neurodegenerative
cause of insomnia in elderly
degeneration of suprachiasmatic nucleus leading to a reduction in melatonin production and decreased external cues
first line treatment for chronic insomnia
CBT-I
some agents used for insomnia in older adults
mirtazapine, trazodone, melatonin
definition of pulmonary nodule
well-defined lesion less than or equal to 3 cm
benign pulmonary nodules appearance
diffuse, central, popcorn, concentric
malignant pulmonary nodules appearance
ground-glass, eccentric
nodule < 6mm
no follow-up
solid nodule less than 8 mm
repeat CT in 6-12 months
solid nodule greater than 8 mm
CT in 3 months then 12 months
ground glass nodule
CT at 6-12 months
part solid between 6-8mm
CT at 3-6 months
part sold >8mm
PET/CT with biopsy/resection
multiple nodules solid
CT 3-6 months
multiple nodules subsolid any size
CT 3-6 months
DDX of benign solitary pulmonary nodule
infectious granuloma, hamartoma, AV malformation
DDX of malignant solitary pulmonary nodule
Adenocarcinoma, SCC, metastatic disease, small cell carcinoma, carcinoid tumor
diagnosis of pulmonary HTN
right heart cath: mean PA>20, pulmonary artery wedge pressure <15, pulmonary vascular resistance > 3 woods units
pathophys changes in PAH
arterial remodelling and inflammation, thickening of adventitia and media, proliferation and migration of smooth muscle cells and fibroblasts
PH group 1
PAH (idiopathic, heritable, drug/toxin-induced)
PH group 2
left heart-induced
PH group 3
lung disease/hypoxia related
PH group 4
chronic thromboembolic
PH group 5
unclear/multifactorial
Pulm HTN EKG
RAD, RVH, right atrial enlargement, RV strain
Pulm HTN CXR
large central pulm arteries, enlarged right heart, could be normal
Pulm HTN TTE
elevated right systolic ventricular pressure
medication treatment for chronic thromboembolic pulmonary htn
riocoguat
treatment of pulm htn
endothelin receptor antagonists (end in -entan), phosphodiesterase 5 inhibitors (sildenafil), treat underlying conditions