Exam 2: Yang Flashcards
What drug is class 2?
BB (esmolol)
What drug is class 4?
CCBs (dilt/verap)
What class is this?
1A
What class is this?
1C
What class is this?
1B
What class is Class 3?
Antiarrythmic (amiodarone)
What is going on in this image? What drugs cause this?
- a widened QRS complex
- class 1C (flecanide)
What is going on in this image? What drugs cause this?
- a increased PR
- BB
What is going on in this image? What drugs cause this?
- lengthened QT
- Quinidine (Class 1A)
- Class 3 (antiarrhythmics: amiodarone)
What is going on in this image? What drugs cause this?
- no change
- Class 1B (lidocaine, mexiletine)
What is going on in Phase 0 on the cardiac action potential? What classes are involved?
- Na+ is going in
- Class 1s (na channel blockers)
What is going on in Phase 2 on the cardiac action potential? What classes are involved?
- Ca+ going in
- CCBs
- class 4
What is going on in Phase 1/3 on the cardiac action potential? What classes are involved?
- K+ going out
- K+ channel blockers (amio/ sotolol)
- class 3
What is going on in Phase 4 on the cardiac action potential? What classes are involved?
- K+ rectifer
- class 2 (bb)
Regarding the membrane potential what is the values both inside and outside the cell?
0 = outside
- 70 = inside
What is the concentration of K+ inside vs. outside the cell?
higher inside than outside
What is the concentration of Na+/Cl- inside vs. outside the cell?
higher outside then inside
What happens to Na+? Where does it flow based on its positive charge when a membrane potential is open?
is flows inside the cell + attracted to a -. If influx occurs then it will more than likely make the inside positive
What happens to K+? Where does it flow based on its positive charge when a membrane potential is open?
since it is inside the cell, it can flow inside and outside but when it flows it is based on the value inside the membrane. If there is a sodium influx it will become positive and potassium will flow out but if it is negative it will flow in.
