Exam 2 terms Flashcards
a slowly progressive noninflammatory disorder of the diarthrodial (synovial) joints
osteoarthritis
a grave coagulopathy resulting from the overstimulation of clotting and anticlotting processes in response to disease or injury
disseminated intravascular coagulation
a marked decrease in the number of red blood cells, white blood cells, and platelets
pancytopenia
the amount of blood pumped by each ventricle in 1 minute
cardiac output
an abnormal decrease in the number of total white blood cells to <4000/uL
leukopenia
the osmotic pressure of a colloid in solution
oncotic pressure
a common disorder characterized by sustained elevation of blood pressure
hypertension
a progressive megaloblastic macrocytic anemia resulting from inadequate gastric secretion of intrinsic factor necessary for absorption of cobalamin
pernicious anemia
a maneuver that involves contraction of the chest muscles on a closed glottis with simultaneous contraction of the abdominal muscles
Valsalva maneuver
hypoxemia
low oxygen tension in the blood characterized by a variety of nonspecific clinical signs and symptoms
a continual process resulting in the dissolution of fibrin to maintain blood in its fluid form
fibrinolysis
nosebleed
epistaxis
a physical examination techinque in which the examiner taps the body with the fingertips or fist
percussion
hereditary bleeding disorders caused by defective or deficient clotting factors
hemophilia
resistance to flexion of the neck
nuchal rigidity
a reduction of the platelet count
thrombocytopenia
an autosomal recessive genetic disorder of inadequate production of normal hemoglobin
thalassemia
a condition marked by excessive platelets; a disorder that occurs with inflammation and some malignant disorders
thrombocytosis
wasting of muscle, characterized by decreased circumference and flabby appearance leading to decreased function and tone
atrophy
an autosomal recessive disease characterized by increased intestinal iron absorption and, as a result, increased tissue iron deposition
hemochromatosis
seizure characterized by a brief staring spell and a very brief loss of consciousness that usually occurs only in children and rarely continues beyond adolescence
absence (petit mal) seizures
the first episode of menstrual bleeding; indicates female has reached puberty
menarche
a physical exmination technique in which the examiner feels the texture, size, consistency, and location of certain body parts with the hands
palpation
a symptom of yellowish discoloration of body tissues that results from an increased concentration of bilirubin in the blood
jaundice
bruising
ecchymoses
vomiting of blood that indicates bleeding in the upper GI tract
hematemesis
techinique in which substances move from the blood through a semipermeable membrane and into a dialysis solution
dialysis
a group of inherited, autosomal recessive disorders characterized by the presence of an abnormal form of hemoglobin in the erythrocyte
sickle cell disease
a malignant condition characterized by proliferation of abnormal gieat, multinucleated cells, called Reed-Sternberg cells which are located in lymph nodes
Hodgkin’s lymphoma
insufficient circulation of thyroid hormones resulting in a hypometabolic state
hypothyroidism
breast conserving surgery that involves the removal of the entire tumor along with a margin of normal tissue
lumpectomy
the physiologic cessation of menses associated with declining ovarian function
menopause
an abnormal reduction of the neutrophil count to <1000uL
neutropenia
malignant neoplasms originating in the bone marrow and lymphatic structures resulting in the proliferation of lymphocytes
lymphomas
the state in which the PaO2 has fallen sufficiently to cause signs and symptoms of inadequate oxygenation
hypoxia
a thromboembolic occlusion of the pulmonary vasculature resulting from thrombi in the venous circulation or right side of the heart that travel as emoli until lodging in the pulmonay vessels
pulmonary embolism
a type of macrophage found in the liver that removes bacteria and toxins from the blood
Kupffer cells
a retrovirus that causes HIV infection and acquired immunodeficiency syndrom
human immunodeficiency virus
a broad term given to a group of malignant diseases characterized by diffuse replacement of bone marrow with proliferating leukocyte precursors
leukemia
an abnormal condition with excessive levels of red blood cells
polycythemia
chronic progressive disease of the liver characterized by extensive degeneration and destruction of the liver parenchymal cells
cirrhosis
a microcytic hypochromic anemia caused by inadequate supplies of iron needed to synthesize hemoglobin; characterized by pallor, fatigue and weakness
iron deficiency anemia
a condition in which malignant neoplastic plasma cells infiltrate the bone marrow and destroy bone
multiple myeloma
increased venous pressure in the portal circulation caused by compression and destruction of the portal and hepatic veins and sinusoids
portal hypertension
distended, tortuous, fragile veins at the lower end of the esophagus that result from portal hypertension
esophageal varices
accumlation of lymph in soft tissue with swelling resulting from inflammation, obstruction, or removal of lymph channels and nodes
lymphedema
erosion of the GI mucosa that results from the digestive action of HCl acid and pepsin
peptic ulcer disease
itching
pruritus
an anemia caused by destruction of RBCs at a rate that exceeds production
hemolytic anemia
small purplish lesions
petechiae
recurrent attacks of acute arthritis associated with increased levels of serum uric acid
gout
a chronic, systemic autoimmune disease characterized by inflammation of connective tissue in the diarthrodial joints, typically with periods of remission and exacerbation
rhematoid arthritis
the thickening of the skin as a result of proliferation of kerationcytes with accentuation of the normal markings of the skin often caused by repeated scratching of a pruritic lesion
lichenification
a syndrome characterized by decreased tissue perfusion and impaired cellular metabolism resulting in an imbalance between the supply of and demand for oxygen and nutrients
shock
an abnormal condition that may affect the heart’s arteries and produce various pathologic effects, especially the reduced flow of oxygen and nutrients to the myocardium
coronary artery disease
an acute life threatening hypersenstivity reaction to a sensitizing substance, such as a drug, chemical, vaccine, food, or insect venom
anaphylactic shock
a disorder of connective tissue characterized by fibrotic, degenerative, and occasionally inflammatory changes in the skin, blood vessels, synovium, skeletal muscle, and internal organs
scleroderma
clinical syndrome characterized by a rise in serum creatinine and/or a reduction in urine output
acute kidney injury
a systemic disorder of mineral and bone metabolism due to progressive deterioration in kidney function
chronic kidney disease
an infectious disease caused by Mycobacterium tuberculosis; usually involves the lungs, but also occurs in the larynx, kidneys, bones, adrenal glands, lymph nodes, and meninges and can be disseminated throughout the body
tuberculosis
a surgical opening into the trachea through which an indwelling tube may be inserted
tracheostomy
an inflammatory condition of the urinary bladder characterized by pain, urgency, frequency of urination, and hematuria
cystitis
an autoimmune disease of the neuromuscular junction characterized by the fluctuating weakness of certain skeletal muscle groups
myasthenia gravis
the transplantation of stem cells obtained from the peripheral blood in an outpatient procedure; often takes more than one procedure to obtain enough stem cells
peripheral stem cell transplantation
a device that is applied externally or internally into the path of flowing blood to augment or replace the action of the ventricle of the heart
ventricular assist device
a tumor arising in cells producing melanin, usually the melanocytes of the skin
malignant melanoma
a diagnostic study using an IV contrast medium excreted through the urinary system; used to examine the structure and function of the urinary system
intravenous pyelogram
the resulting damage to the heart muscle and heart valves from rheumatic fever, a chronic condition characterized by scarring and deformity of the heart valves
rheumatic heart disease
an acute, life-threatening situation in which the lung alveoli become filled with serous or serosanguineous fluid, caused most commonly by heart failure
pulmonary edema
a chronic multisystem inflammatory disorder associated with abnormalities of the immune system
systemic lupus erythematosus
a systemic inflammatory response to infection
sepsis
a chronic inflammatory lung disease that results in airflow obstruction; characterized by recurring episodes of paroxymal dyspnea, wheezing on expiration, and/or inspiration caused by constriction of the bronchi, coughing, and viscous mucoid bronchial secretions
asthma
a chronic, progressive degenerative disorder of the central nervous system characterized by disseminated demylination of nerve fibers of the brain and spinal cord
multiple sclerosis
redness or inflammation of the skin or mucous membranes that result from dilation and congestion of superficial capillaries
erythema
the presence of kidney damage or decreased glomerular filtration rate for at least 3 months with functional or structural abnormalities, with or without decreased glomerular filtration rate
chronic kidney disease
a chronic skin disorder characterized by circumscribed red patches covered by thick, dry, silvery, adherent scales
psoriasis
a pruritic skin eruption characterized by transient wheals of varying shapes and sizes with well-defined erythematous margins and pale centers; usually an allergic phenomenon
urticaria
a metabolic bone disease characterized by low bone mass and structural deterioration of bone tissue, leading to increased bone fragility and pathologic fractures
osteoporosis
a chronic neurologic disorder caused by the brain’s inability to regulate sleep-wake cycles normally; results in fleeting urges to sleep throughout the day
narcolepsy
an immune related inflammation of the glomeruli characterized by proteinuria, hematuria, decreased urine production, and edema
glomerulonephritis
a malignant tumor that originates from embryonal mesoderm that becomes connective tissue, muscle, bone and fat
sarcoma