Exam 2 Prototypes Flashcards
Adrenergic bronchodilators
Epinephrine (beta 1 and beta 2 subq, often given in the ED)
Adrenergic inhaler
albuterol (Proventil) selective Beta 2, short acting
Anticholinergic for respiratory inhaler
ipratropium bromide (Atrovent)
Xanthines or “ophyllines”
aminophylline
Corticosteroids chronic use inhalers
flunisolide (Aerobid)
Corticosteroids systemic
prednisone/methylprednisolone
Mast cell stabilizers
cromolyn sodium (Intal)
Leukotriene inhibitor
zafirlukast (Accolate)
1st gen Antihistamine
diphenhydramine (Benadryl)
Decongestants prototypes
Phenylephrine (Neosynephrine), Pseudoephedrine (Sudafed)
Central acting Antitussives
codeine, dextromethorphan
Peripheral acting Antitussives
glycerin
Expectorant
Guaifenesin
Mucolytic
Normal saline, acetylcysteine (Mucomyst)
Positive Inotropic, cardiovascular
digoxin (Lanoxin)
Na channel blockers (Class IB)
lidocaine (Xylocaine)
Beta Adrenergic Blockers (Class II):
propranolol (Inderal)
K channel blockers (Class III)
amiodarone (Cordarone)
Calcium channel blockers (Class IV):
verapamil (Calan)
Nitrates
nitroglycerin (Nitrostat)
Beta-adrenergic blockers:
propranolol (Inderal)
Calcium channel blockers:
verapamil (Calan)
Thiazides
hydrochlorothiazide
Loop
furosemide (Lasix)
K+ sparing or aldosterone antagoinst:
spironolactone (Aldactone)
Osmotic diuretic
mannitol (Osmitrol)
Angiotensin converting enzyme (ACE) inhibitors:
captopril (Capoten)
Angiotensin II receptor blockers:
losartan (Cozaar)
Calcium channel blockers:
verapamil (Calan)
Direct acting vasodilator (anti-hypertensive)
hydralazine (Apresoline)
Centrally acting alpha 2 agonist (anti-hypertensive):
clonidine (Catapres)
Peripheral acting alpha 1 blocker (anti-hypertensive):
prazosin (Minipress)
HTN crisis:
sodium nitroprusside (Nitropress)
American Heart Association Recommendations for patients with Heart Failure meds (3):
ACE inhibitor + Beta-blocker + Loop or Thiazide diuretic May also add: digoxin +/or Antianginal (nitrates) +/or vasodilator: hydralazine (Apresoline)
Outpatient Heart Failure Treatment
Primacor or Inocor
Anticoagulants prototype
Heparin
Heparin - antidote:
protamine sulfate
Warfarin (Coumadin) – antidote:
vitamin K
Glycoprotein 11b/111a receptor antagonist:
tirofiban (Aggrastat)
Thrombolytic
Alteplase (Activase)
Alteplase (Activase) - antidote
amicar
Hyperlipidemia
Statins
Statins prototype
lovastatin (Mevacor)
Antiplatelets (4):
- ASA 2. NSAID 3. clopidogrel (Plavix) 4. Glycoprotein 11b/111a receptor antagonist: tirofiban (Aggrastat)
American Heart Association Recommendations for Patients with CVD (5):
ACE Inhibitor + Beta-blocker + ASA + Statin + nitroglycerin PRN
Penicillin (beta lactam ring):
penicillin G
Cephalosporins (beta lactam ring):
cefazolin (Kefzol)
antibiotics that inhibit cell wall synthesis (3):
- Penicillin (beta lactam ring): penicillin G 2. Cephalosporins (beta lactam ring): cefazolin (Kefzol) 3. Vancomycin
antibiotics that inhibit bacterial protein synthesis (3):
- Aminoglycosides: gentamicin 2. Macrolides: erythromycin 3. Tetracycline
Macrolides prototype
erythromycin
Aminoglycosides prototype
gentamicin
antibiotics that inhibit nucleic acid synthesis
Fluoroquinolones: ciprofloxacin (Cipro)
Fluoroquinolones prototype
ciprofloxacin (Cipro)
ANTIVIRALS
Acyclovir (Zovirax)
antibiotics that inhibit metabolic pathways
Sulfonamides: sulfamethoxazole-trimethoprim (Bactrim, Septra)
Sulfonamides
sulfamethoxazole-trimethoprim (Bactrim, Septra)
4 types of Antiarrhythmics (ventricular):
Na channel blockers (Class IB): lidocaine (Xylocaine) Beta Adrenergic Blockers (Class II): propranolol (Inderal) K channel blockers (Class III): amiodarone (Cordarone) Calcium channel blockers (Class IV): verapamil (Calan)
3 antianginals
Nitrates: nitroglycerin (Nitrostat) Beta-adrenergic blockers: propranolol (Inderal) Calcium channel blockers: verapamil (Calan)
Diuretics (4)
Thiazides: hydrochlorothiazide Loop: furosemide (Lasix) K+ sparing or aldosterone antagoinst: spironolactone (Aldactone) Osmotic diuretic: mannitol (Osmitrol)
Antihypertensives
- Angiotensin converting enzyme (ACE) inhibitors: captopril (Capoten) - Angiotensin II receptor blockers: losartan (Cozaar) - Calcium channel blockers: verapamil (Calan) - Beta-blocker: propranolol (Inderal) - Direct acting vasodilator: hydralazine (Apresoline) - Centrally acting alpha 2 agonist: clonidine (Catapres) - Peripheral acting alpha 1 blocker: prazosin (Minipress) - HTN crisis: sodium nitroprusside (Nitropress)
While taking the diuretic furosemide (Lasix), patients need to have their serum electrolytes monitored to detect: A. Hypokalemia. B. Hyperkalemia. C. Hypercalcemia. D. Hyponatremia.
A. Hypokalemia – loop diuretics can cause a decrease in K levels
Patients on Sulfa drugs should be encouraged to: Drink small amounts of water. Drink large amounts of water. Take it without regard to meals. Take it with milk products.
Drink large amounts of water. (to prevent crystal formation in the kidneys)
Which of the following factors predispose a patient to infection? Complete bed rest Hypotension Normal bacteria flora in the colon Angina
Complete bed rest – changes the breathing pattern and makes them at higher risk for pneumonia and skin breakdown
Your patient has a mixed infection and is receiving cefazolin, a cephalosporin, and gentamicin, an aminoglycoside antibiotic. To minimize adverse effects, which lab test should be closely monitored? Calcium Potassium Creatinine Sodium
Creatinine – Creatinine is the most reliable test of kidney function. As this lab value rises it is correlated with increasing damage to the kidney.
What is the purpose of dysrhythmic drugs? To change the flow of blood through the heart. To substitute for implantable cardiac defibrillators. To prevent, suppress, or treat a disturbance in cardiac rhythm. To increase or decrease the contractility of the heart muscle.
To prevent, suppress, or treat a disturbance in cardiac rhythm.
Your patient is receiving alteplase (Activase). She complains of abdominal pain and vomits 100 mL of dark coffee ground emesis. Her BP has dropped to 80/40 mmHg. You should anticipate the administration of which of the following drugs? Protamine sulfate Vitamin K Amicar Narcan
Amicar
Your patient takes a statin, Zocor, for hypercholesteremia. She has a history of alcohol and drug abuse. Which of the following interventions would be appropriate for her? Baseline and serial liver function tests Monthly CBC Monthly urine drug screen Baseline renal function tests
Baseline and serial liver function tests
The difference between Heparin and Activase is that: (A) Heparin requires an unsafe dose to dissolve clots (B) Heparin dissolves clots whereas Activase prevents further clot formation (C) Heparin prevents further clot formation whereas Activase dissolves clots (D) Activase decreases the risk of hemorrhage during therapy
(C) Heparin prevents further clot formation whereas Activase dissolves clots
Your patient is being prescribed a statin, Mevacor. Patient teaching should include to contact the health care provider immediately for: Severe muscle pain. Diarrhea. Intermittent headaches. Nausea.
Severe muscle pain – Rhadomyolysis, a serious adverse drug effect
Epinephrine (beta 1 and beta 2 subq, often given in the ED)
Adrenergic bronchodilators
albuterol (Proventil) selective Beta 2, short acting
Adrenergic inhaler
ipratropium bromide (Atrovent)
Anticholinergic for respiratory inhaler
aminophylline
Xanthines or “ophyllines”
flunisolide (Aerobid)
Corticosteroids chronic use inhalers
prednisone/methylprednisolone
Corticosteroids systemic
cromolyn sodium (Intal)
Mast cell stabilizers
zafirlukast (Accolate)
Leukotriene inhibitor
diphenhydramine (Benadryl)
1st gen Antihistamine
Phenylephrine (Neosynephrine), Pseudoephedrine (Sudafed)
Decongestants prototypes
codeine, dextromethorphan
Central acting Antitussives
glycerin
Peripheral acting Antitussives
Guaifenesin
Expectorant
Normal saline, acetylcysteine (Mucomyst)
Mucolytic
digoxin (Lanoxin)
Positive Inotropic, cardiovascular
lidocaine (Xylocaine)
Na channel blockers (Class IB)
propranolol (Inderal)
Beta Adrenergic Blockers (Class II):
amiodarone (Cordarone)
K channel blockers (Class III)
verapamil (Calan)
Calcium channel blockers (Class IV):
nitroglycerin (Nitrostat)
Nitrates
propranolol (Inderal)
Beta-adrenergic blockers:
verapamil (Calan)
Calcium channel blockers:
hydrochlorothiazide
Thiazides
furosemide (Lasix)
Loop
spironolactone (Aldactone)
K+ sparing or aldosterone antagoinst:
mannitol (Osmitrol)
Osmotic diuretic
captopril (Capoten)
Angiotensin converting enzyme (ACE) inhibitors:
losartan (Cozaar)
Angiotensin II receptor blockers:
verapamil (Calan)
Calcium channel blockers:
hydralazine (Apresoline)
Direct acting vasodilator (anti-hypertensive)
clonidine (Catapres)
Centrally acting alpha 2 agonist (anti-hypertensive):
prazosin (Minipress)
Peripheral acting alpha 1 blocker (anti-hypertensive):
sodium nitroprusside (Nitropress)
HTN crisis:
ACE inhibitor + Beta-blocker + Loop or Thiazide diuretic May also add: digoxin +/or Antianginal (nitrates) +/or vasodilator: hydralazine (Apresoline)
American Heart Association Recommendations for patients with Heart Failure meds (3):
Primacor or Inocor
Outpatient Heart Failure Treatment
Heparin
Anticoagulants prototype
protamine sulfate
Heparin - antidote:
vitamin K
Warfarin (Coumadin) – antidote:
tirofiban (Aggrastat)
Glycoprotein 11b/111a receptor antagonist:
Alteplase (Activase)
Thrombolytic
amicar
Alteplase (Activase) - antidote
Statins
Hyperlipidemia
lovastatin (Mevacor)
Statins prototype
- ASA 2. NSAID 3. clopidogrel (Plavix) 4. Glycoprotein 11b/111a receptor antagonist: tirofiban (Aggrastat)
Antiplatelets (4):
ACE Inhibitor + Beta-blocker + ASA + Statin + nitroglycerin PRN
American Heart Association Recommendations for Patients with CVD (5):
penicillin G
Penicillin (beta lactam ring):
cefazolin (Kefzol)
Cephalosporins (beta lactam ring):
- Penicillin (beta lactam ring): penicillin G 2. Cephalosporins (beta lactam ring): cefazolin (Kefzol) 3. Vancomycin
antibiotics that inhibit cell wall synthesis (3):
- Aminoglycosides: gentamicin 2. Macrolides: erythromycin 3. Tetracycline
antibiotics that inhibit bacterial protein synthesis (3):
erythromycin
Macrolides prototype
gentamicin
Aminoglycosides prototype
Fluoroquinolones: ciprofloxacin (Cipro)
antibiotics that inhibit nucleic acid synthesis
ciprofloxacin (Cipro)
Fluoroquinolones prototype
Acyclovir (Zovirax)
ANTIVIRALS
Sulfonamides: sulfamethoxazole-trimethoprim (Bactrim, Septra)
antibiotics that inhibit metabolic pathways
sulfamethoxazole-trimethoprim (Bactrim, Septra)
Sulfonamides
Na channel blockers (Class IB): lidocaine (Xylocaine) Beta Adrenergic Blockers (Class II): propranolol (Inderal) K channel blockers (Class III): amiodarone (Cordarone) Calcium channel blockers (Class IV): verapamil (Calan)
4 types of Antiarrhythmics (ventricular):
Nitrates: nitroglycerin (Nitrostat) Beta-adrenergic blockers: propranolol (Inderal) Calcium channel blockers: verapamil (Calan)
3 antianginals
Thiazides: hydrochlorothiazide Loop: furosemide (Lasix) K+ sparing or aldosterone antagoinst: spironolactone (Aldactone) Osmotic diuretic: mannitol (Osmitrol)
Diuretics (4)
- Angiotensin converting enzyme (ACE) inhibitors: captopril (Capoten) - Angiotensin II receptor blockers: losartan (Cozaar) - Calcium channel blockers: verapamil (Calan) - Beta-blocker: propranolol (Inderal) - Direct acting vasodilator: hydralazine (Apresoline) - Centrally acting alpha 2 agonist: clonidine (Catapres) - Peripheral acting alpha 1 blocker: prazosin (Minipress) - HTN crisis: sodium nitroprusside (Nitropress)
Antihypertensives